Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
137(1)
Published: Nov. 7, 2024
Abstract
Precise
synthesis
of
carboxylic
acids
via
catalytic
carboxylation
with
CO
2
is
highly
appealing.
Although
considerable
advancements
have
been
achieved
in
difunctionalizing
unsaturated
hydrocarbons,
the
asymmetric
variants
are
conspicuously
underdeveloped,
particularly
addressing
axially
chiral
alkenes.
Herein,
we
report
first
atroposelective
alkynes
.
A
variety
valuable
obtained
good
yields
and
high
chemo‐,
regio‐,
Z/E
enantio‐selectivities.
Notably,
an
unexpected
anti
‐selective
carbo‐carboxylation
observed
sp
‐hybrid
carbo‐electrophile‐initiated
reductive
alkynes.
Mechanistic
studies
including
DFT
calculation
elucidate
origin
induction
‐selectivity
vinyl‐carboxylation
Bulletin of the Chemical Society of Japan,
Journal Year:
2023,
Volume and Issue:
97(1)
Published: Dec. 1, 2023
Abstract
Nanotechnology
has
revealed
the
science
of
nanoscale.
The
global
challenge
that
will
follow
is
to
build
functional
materials
with
knowledge
nanoscale
phenomena.
This
task
carried
out
by
nanoarchitectonics
as
a
postnanotechnology
concept.
goal
material
systems
architecting
atoms,
molecules,
and
nanomaterials
building
blocks.
Fundamentally,
all
are
made
atoms
molecules.
Therefore,
nanoarchitectonics,
which
architects
from
can
be
universal
way
create
materials.
It
may
said
method
for
everything
in
science.
From
basic
units,
living
cells,
complex
systems,
components
nanoarchitectonics.
paper
presents
recent
examples
research
at
various
size
levels,
atomic
cellular
level,
specifically,
(i)
atomistic
(ii)
molecular
(iii)
supramolecular
(iv)
inorganic
(v)
biomolecular
(vi)
cell-mimic
(vii)
cell-based
possibility
science,
an
integrative
then
explored.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(5), P. 2919 - 2927
Published: Jan. 26, 2024
Dicarboxylic
acids
and
derivatives
are
important
building
blocks
in
organic
synthesis,
biochemistry,
the
polymer
industry.
Although
catalytic
dicarboxylation
with
CO2
represents
a
straightforward
sustainable
route
to
dicarboxylic
acids,
it
is
still
highly
challenging
limited
generation
of
achiral
or
racemic
acids.
To
date,
asymmetric
give
chiral
has
not
been
reported.
Herein,
we
report
first
1,3-dienes
via
Cu
catalysis.
This
strategy
provides
an
efficient
environmentally
benign
high
regio-,
chemo-,
enantioselectivities.
The
copper
self-relay
catalysis,
that
is,
Cu-catalyzed
boracarboxylation
carboxylated
allyl
boronic
ester
intermediates
subsequent
carboxylation
C–B
bonds
dicarboxylates,
key
success
this
dicarboxylation.
Moreover,
protocol
exhibits
broad
substrate
scope,
good
functional
group
tolerance,
easy
product
derivatizations,
facile
synthesis
liquid
crystalline
polyester
drug-like
scaffolds.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(22)
Published: March 26, 2024
Abstract
Upgrading
CO
2
to
value‐added
chiral
molecules
via
catalytic
asymmetric
C−C
bond
formation
is
a
highly
important
yet
challenging
task.
Although
great
progress
on
the
of
centrally
carboxylic
acids
has
been
achieved,
construction
axially
with
never
reported
date.
Herein,
we
report
first
synthesis
,
which
enabled
by
nickel‐catalyzed
dynamic
kinetic
reductive
carboxylation
racemic
aza‐biaryl
triflates.
A
variety
acids,
are
valuable
but
difficult
obtain
catalysis,
generated
in
an
enantioconvergent
version.
This
new
methodology
features
good
functional
group
tolerance,
easy
scale‐up,
facile
transformation
and
avoids
cumbersome
steps,
handling
organometallic
reagents
using
stoichiometric
materials.
Mechanistic
investigations
indicate
process
induced
nickel
catalysis.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(22)
Published: March 26, 2024
Abstract
Upgrading
CO
2
to
value‐added
chiral
molecules
via
catalytic
asymmetric
C−C
bond
formation
is
a
highly
important
yet
challenging
task.
Although
great
progress
on
the
of
centrally
carboxylic
acids
has
been
achieved,
construction
axially
with
never
reported
date.
Herein,
we
report
first
synthesis
,
which
enabled
by
nickel‐catalyzed
dynamic
kinetic
reductive
carboxylation
racemic
aza‐biaryl
triflates.
A
variety
acids,
are
valuable
but
difficult
obtain
catalysis,
generated
in
an
enantioconvergent
version.
This
new
methodology
features
good
functional
group
tolerance,
easy
scale‐up,
facile
transformation
and
avoids
cumbersome
steps,
handling
organometallic
reagents
using
stoichiometric
materials.
Mechanistic
investigations
indicate
process
induced
nickel
catalysis.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
64(1)
Published: Aug. 16, 2024
Herein,
we
report
a
synergistic
photoredox/palladium
catalytic
system
for
the
efficient
enantioconvergent
synthesis
of
axially
chiral
esters
from
racemic
heterobiaryl
(pseudo)halides
(bromides/triflates)
with
CO
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
64(1)
Published: Nov. 7, 2024
Abstract
Precise
synthesis
of
carboxylic
acids
via
catalytic
carboxylation
with
CO
2
is
highly
appealing.
Although
considerable
advancements
have
been
achieved
in
difunctionalizing
unsaturated
hydrocarbons,
the
asymmetric
variants
are
conspicuously
underdeveloped,
particularly
addressing
axially
chiral
alkenes.
Herein,
we
report
first
atroposelective
alkynes
.
A
variety
valuable
obtained
good
yields
and
high
chemo‐,
regio‐,
Z/E
enantio‐selectivities.
Notably,
an
unexpected
anti
‐selective
carbo‐carboxylation
observed
sp
‐hybrid
carbo‐electrophile‐initiated
reductive
alkynes.
Mechanistic
studies
including
DFT
calculation
elucidate
origin
induction
‐selectivity
vinyl‐carboxylation
Journal of Physics Condensed Matter,
Journal Year:
2024,
Volume and Issue:
37(5), P. 053001 - 053001
Published: Nov. 8, 2024
Abstract
Nanotechnology
has
elucidated
scientific
phenomena
of
various
materials
at
the
nano-level.
The
next
step
in
developments
is
to
build
up
materials,
especially
condensed
matter,
based
on
such
nanotechnology-based
knowledge.
Nanoarchitectonics
can
be
regarded
as
a
post-nanotechnology
concept.
In
nanoarchitectonics,
functional
material
systems
are
architected
from
nanounits.
Here,
this
review
would
like
focus
layered
structures
terms
structure
formation.
unit
mostly
two-dimensional
or
thin-film
materials.
They
attractive
that
have
attracted
much
attention
modern
matter
science.
By
organizing
them
into
structures,
we
expect
develop
functions
communication
between
layers.
Building
by
assembling
nano-layers
units
typical
approach
nanoarchitectonics.
discussion
will
divided
following
categories:
hard
hybrid,
soft
and
living
object.
For
each
target,
several
recent
research
examples
given
illustrate
discussion.
This
paper
extract
what
aspects
considered
important
creation
component.
Layering
strategies
need
adapted
characteristics
components.
type
structural
precision
functionality
required
highly
dependent
flexibility
mobility
Furthermore,
needed
nanoarchitectonics
discussedas
future
perspectives.
