Reactions Weekly, Journal Year: 2021, Volume and Issue: 1883(1), P. 151 - 151
Published: Nov. 1, 2021
Language: Английский
Acta Neurologica Scandinavica, Journal Year: 2021, Volume and Issue: 145(1), P. 5 - 9
Published: Nov. 8, 2021
SARS-CoV-2 and adverse reactions to vaccinations show a tropism for neuronal structures tissues. This narrative review was conducted collect discuss published data about neurological side effects of vaccines in order discover type, frequency, treatment, outcome these effects. The most frequent are headache, Guillain-Barre syndrome (GBS), venous sinus thrombosis (VST), transverse myelitis. Other occur much lower frequency. Neurological with any the approved but VST particularly occurs after vaccination vector-based vaccines. Treatment is not at variance from similar conditions due other causes. worst associated VST, why it should be missed treated appropriately time. In conclusion, safety concerns against backed by an increasing number studies reporting them GBS, Healthcare professionals, neurologists involved management patients having undergone vaccinations, aware stay vigilant recognize early treat adequately.
Language: Английский
Citations
153
European journal of medical research, Journal Year: 2023, Volume and Issue: 28(1)
Published: Feb. 25, 2023
Following the COVID-19 virus epidemic, extensive, coordinated international research has led to rapid development of effective vaccines. Although vaccines are now considered best way achieve collective safety and control mortality, due critical situation, these have been issued emergency use licenses some their potential subsequence side effects overlooked. At same time, there many reports after getting a vaccine. According reports, vaccination can an adverse event, especially on nervous system. The most important common complications cerebrovascular disorders including cerebral venous sinus thrombosis, transient ischemic attack, intracerebral hemorrhage, stroke, demyelinating transverse myelitis, first manifestation MS, neuromyelitis optica. These often acute transient, but they be severe even fatal in few cases. Herein, we provided comprehensive review documents reporting neurological databases from 2020 2022 discussed possibly caused by vaccination.
Language: Английский
Citations
60
Diagnostics, Journal Year: 2022, Volume and Issue: 12(7), P. 1555 - 1555
Published: June 26, 2022
The novel mRNA vaccinations against COVID-19 are gaining worldwide attention for their potential efficacy, as well the diagnosis of some post-vaccination-reported adverse reactions. In this state-of-the-art review article, we present current evidence regarding mainly spontaneous allergic reactions, skin occurrences, vascular, blood, endocrine and heart events, respiratory reports, gastrointestinal, hepatic kidney reproductive pregnancy issues muscle ear, eye, neurologic psychiatric events following vaccination COVID-19. We further strategies, provide important information side effects associated with spike protein based LNP-mRNA vaccine its adjuvants, all possible dangerous roles protein, discuss our expert opinion on knowns unknowns towards topic.
Language: Английский
Citations
40
Seizure, Journal Year: 2024, Volume and Issue: 121, P. 8 - 16
Published: July 18, 2024
Language: Английский
Citations
4
Epilepsy & Behavior, Journal Year: 2022, Volume and Issue: 134, P. 108822 - 108822
Published: June 29, 2022
Language: Английский
Citations
15
Frontiers in Immunology, Journal Year: 2022, Volume and Issue: 13
Published: Dec. 7, 2022
Several COVID-19 vaccines list "uncontrolled epilepsy" as a contraindication for vaccination. This consequently restricts vaccination against in patients with epilepsy (PWE). However, there is no strong evidence that can exacerbate conditions PWE. study aims to determine the impact of on PWE were prospectively recruited from 25 centers. We recorded seizure frequency at three time periods (one month before first and one after second vaccinations). A generalized linear mixed-effects model (GLMM) was used analysis, adjusted incidence rate ratio (AIRR) 95% CI presented interpreted accordingly. Overall, 859 included analysis. Thirty-one (3.6%) 35 (4.1%) found have increased two doses, respectively. Age had an interaction time. The adults decreased by 81% dose (AIRR=0.19, CI:0.11-0.34) 85% (AIRR=0.16, CI:0.08-0.30). In juveniles (<18), it 25% (AIRR=0.75, CI:0.42-1.34) 51% (AIRR=0.49, CI:0.25-0.95), Interval between last (ILSFV) significant effect Seizure hereditary significantly higher than unknown etiology (AIRR=1.95, CI: 1.17-3.24). Two hundred seventeen (25.3%) experienced non-epileptic but not serious adverse reactions. inactivated vaccine does increase limitations should focus aspects other control status. Juvenile be greater concern because they lower safety. Finally, reduce dosage anti-seizure medication during peri-vaccination period.
Language: Английский
Citations
7
Seminars in Neurology, Journal Year: 2023, Volume and Issue: 43(02), P. 297 - 311
Published: April 1, 2023
Abstract The benefits of coronavirus disease 2019 (COVID-19) vaccination significantly outweigh its risks on a public health scale, and has been crucial in controlling the spread SARS-CoV-2. Nonetheless, several reports adverse events following have published. To summarize to date assess extent quality evidence regarding possible serious neurological COVID-19 vaccination, focusing Food Drug Administration (FDA)-approved vaccines United States (BNT162b2, mRNA-1273, Ad26.COV2.S). A review literature from five major electronic databases (PubMed, Medline, Embase, Cochrane Library, Google Scholar) was conducted between December 1, 2020 June 5, 2022. Articles included were systematic reviews meta-analysis, cohort studies, retrospective case–control case series, reports. Editorials, letters, animal studies excluded, since these did not include quantitative data side effects human subjects. Of 149 total articles 97 (65%) or series. Three phase 3 trials initially for BNT162b2, MRNA-1273, Ad26.COV2.S analysis. amount context FDA-approved vaccinations is overall low tier. current body continues suggest that high safety profile; however, must continue be closely monitored.
Language: Английский
Citations
3
Epilepsy & Behavior, Journal Year: 2023, Volume and Issue: 147, P. 109387 - 109387
Published: Aug. 23, 2023
Language: Английский
Citations
2
Nöro Psikiyatri Arşivi, Journal Year: 2023, Volume and Issue: unknown
Published: Jan. 1, 2023
The current study evaluates the effects of COVID-19 infection and safety vaccines in patients with epilepsy (PWEs).
Language: Английский
Citations
1
Vestnik of Saint Petersburg University Medicine, Journal Year: 2023, Volume and Issue: 18(2), P. 112 - 140
Published: Jan. 1, 2023
Acute respiratory infection caused by the SARS-CoV-2 coronavirus was cause of pandemic announced in March 2020. To prevent this disease, various vaccines have been developed and introduced into mass use, including on an innovative gene platform. The aim review is to analyze foreign literature post-vaccination complications with use vaccines, as well whole-virion for period 2021 — January 2023. sources used publication were obtained from Medline database, articles peer-reviewed journals official reports. Post-vaccination are associated specific damage organs or systems either directly vaccine itself indirectly a result exacerbation chronic process. pathogenesis depends composition vaccine. All grouped systems. Vaccines containing antigens can activate autoimmune reactions due homology, activation existing predisposed patients, which confirmed effectiveness immunosuppressive therapy. Innovative platforms using technologies so complex profoundly active that they be broad medical practice only after thorough comprehensive study effects mechanisms. Scientific achievements should follow ethical principles healing, above all primum non nocere. Experts around world emphasize need continued monitoring people’s condition order protect their health assess long-term safety drugs.
Language: Английский
Citations
1