High Q-Factor, High Contrast, and Multi-Band Optical Sensor Based on Plasmonic Square Bracket Dimer Metasurface DOI Creative Commons
Bin Ni,

Guanghu Chu,

Zheyang Xu

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(5), P. 421 - 421

Published: Feb. 25, 2024

A high-performance resonant metasurface is rather promising for diverse application areas such as optical sensing and filtering. Herein, a metal-insulator-metal (MIM) sensor with merits of high quality-factor (Q-factor), multiple operating bands, spectrum contrast proposed using plasmonic square bracket dimer metasurface. Due to the complex itself, structure two oppositely placed brackets, array configuration, kinds mode coupling can be devised in inner outer elements within metasurface, enabling four channels sensitivities higher than 200 nm/RIU refractive index sensing. Among them, special channel based on reflection-type surface lattice resonance (SLR) mechanism has full width at half maximum (FWHM) only 2 nm, peak-to-dip signal 0.82, Q-factor 548, it also behave good thickness measurement deposition layer. The multi-band work normally large or range, number further increased by simply breaking structural symmetry changing polarization angle incident light. Equipped unique advantages, suggested great potential sensing, monitoring, filtering, other applications.

Language: Английский

Exosome Isolation and Detection: From Microfluidic Chips to Nanoplasmonic Biosensor DOI
Jianing Shen,

Zhengtai Ma,

Jiaqi Xu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: April 27, 2024

Exosomes are becoming more widely acknowledged as significant circulating indicators for the prognosis and diagnosis of cancer. Circulating exosomes essential to development spread cancer, according a growing body research. Using existing technology, characterizing is quite difficult. Therefore, direct, sensitive, targeted approach exosome detection will aid in illness prognosis. The review discusses new strategies isolation technologies from microfluidic chips nanoplasmonic biosensors, analyzing advantages limitations these technologies. This serves researchers better understand methods help develop isolating detecting devices clinical applications.

Language: Английский

Citations

10
Aptamer-based biosensors for wastewater surveillance of influenza virus, SARS-CoV-2, and norovirus: A comprehensive review DOI Creative Commons
Yilei Wang, Mohan Amarasiri, Wakana Oishi

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123484 - 123484

Published: March 1, 2025

Wastewater-based epidemiological (WBE) surveillance has emerged as a crucial tool for monitoring infectious diseases within communities. However, its broader application is frequently constrained by the high costs, labor-intensive processes, and extended timeframes required sample collection, transportation, processing. Aptamer-based biosensors offer promising alternative, leveraging specific binding properties of aptamers to biomolecules on-site rapid quantification disease biomarkers in wastewater. This review systematically evaluates recent advancements aptamer-based detection key pathogens, including influenza viruses, SARS-CoV-2, norovirus, wastewater matrices. The discussion encompasses technical stability reliability signal transmission associated with these biosensors, well current challenges faced real-world implementation. Noteworthy progress been made development WBE, achieving limits low femtomolar (fM) levels buffer linear dynamic ranges extending up five orders magnitude viruses such SARS-CoV-2. Despite this progress, considerable hurdles remain be addressed before technologies can effectively deployed practical settings, especially complex environments. Key factors affecting performance include matrix interference, environmental variability, diminished both viral targets aptamer-target interactions not only highlights but also outlines potential avenues future research aimed at enhancing functionality applicability ultimately contributing more effective public health strategies.

Language: Английский

Citations

0
Recent Advancements in Microfluidic Biosensors for Clinical Applications DOI Creative Commons
Haiyan Wang, Wenjuan Wu

iLABMED, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

ABSTRACT The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid accurate detection complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, treatment management. Advances novel biomaterials have led to device integration into wearable implantable systems point‐of‐care testing. Here, we review recent advances clinical detecting nucleic acids, proteins, metabolites, pathogens, cellular components. We outline the prospects devices based on analysis biofluids such as sweat discuss remaining challenges facing application biosensors.

Language: Английский

Citations

0
The development of droplet-based microfluidic virus detection technology for human infectious diseases DOI

Jiayan Liu,

Bingyang Zhang, Li Wang

et al.

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(7), P. 971 - 978

Published: Jan. 1, 2024

Virus-based human infectious diseases have a significant negative impact on people's health and social development. The need for quick, accurate, early viral infection detection in preventive medicine is expanding. A microfluidic control particularly suitable point-of-care-testing virus diagnosis due to its advantages of low sample consumption, quick speed, simple operation, multi-functional integration, small size, easy portability. It also thought development potential wide range application prospects the research technology. In an effort aid researchers creating novel tools detection, this review highlights recent developments droplet-based microfluidics discusses challenges opportunities rapid detection.

Language: Английский

Citations

3
High Q-Factor, High Contrast, and Multi-Band Optical Sensor Based on Plasmonic Square Bracket Dimer Metasurface DOI Creative Commons
Bin Ni,

Guanghu Chu,

Zheyang Xu

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(5), P. 421 - 421

Published: Feb. 25, 2024

A high-performance resonant metasurface is rather promising for diverse application areas such as optical sensing and filtering. Herein, a metal-insulator-metal (MIM) sensor with merits of high quality-factor (Q-factor), multiple operating bands, spectrum contrast proposed using plasmonic square bracket dimer metasurface. Due to the complex itself, structure two oppositely placed brackets, array configuration, kinds mode coupling can be devised in inner outer elements within metasurface, enabling four channels sensitivities higher than 200 nm/RIU refractive index sensing. Among them, special channel based on reflection-type surface lattice resonance (SLR) mechanism has full width at half maximum (FWHM) only 2 nm, peak-to-dip signal 0.82, Q-factor 548, it also behave good thickness measurement deposition layer. The multi-band work normally large or range, number further increased by simply breaking structural symmetry changing polarization angle incident light. Equipped unique advantages, suggested great potential sensing, monitoring, filtering, other applications.

Language: Английский

Citations

2