Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Fish Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: 51(1)
Published: Jan. 6, 2025
Language: Английский
Citations
1Journal of genetics and genomics/Journal of Genetics and Genomics, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
1Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Journal Year: 2025, Volume and Issue: unknown, P. 111804 - 111804
Published: Jan. 1, 2025
Language: Английский
Citations
0Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742173 - 742173
Published: Jan. 1, 2025
Language: Английский
Citations
0Marine Biotechnology, Journal Year: 2025, Volume and Issue: 27(1)
Published: Feb. 1, 2025
Language: Английский
Citations
0Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742461 - 742461
Published: March 1, 2025
Language: Английский
Citations
0Genes, Journal Year: 2024, Volume and Issue: 15(9), P. 1238 - 1238
Published: Sept. 23, 2024
17α-Methyltestosterone (MT) is a widely used androgen for all-male fish production in aquaculture. However, the molecular mechanism underlying MT-induced masculinization remains unclear. In this study, we aim to identify key gene responsible using Nile tilapia (Oreochromis niloticus) amhy, dmrt1, and gsdf mutants, which exhibit male-to-female sex reversal. fry from these three mutant lines were treated with 50 μg/g MT 5 30 days after hatching (dah). The results showed that amhy but not dmrt1 masculinized by treatment. Gonadal transcriptome analysis revealed genes involved steroidogenesis germ cell development MT-treated mutants exhibited similar expression pattern of wild type (WT) XX. addition, cannot be co-treatment aromatase inhibitor fadrozole. treatment completely blocked early steroidogenic enzyme (Star2, Cyp17a2, Cyp19a1a) independent gsdf, dmrt1. A luciferase directly suppressed basal Sf-1-activated cyp19a1a promoter activity through ara arb cultured HEK293 cells. Furthermore, inhibited proliferation mutants. Consistently, was induced WT XX, -amhy, -gsdf Taken together, suggest indispensable functions inhibiting steroid synthesis activating promote testis development.
Language: Английский
Citations
2Andrology, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 27, 2024
Oligoasthenoteratozoospermia (OAT) is a common cause of male infertility, which the causes remain largely unknown. Recently, BCORL1 was identified as contributor to infertility from non-obstructive azoospermia (NOA) OAT.
Language: Английский
Citations
1Aquaculture Reports, Journal Year: 2024, Volume and Issue: 37, P. 102247 - 102247
Published: July 15, 2024
Language: Английский
Citations
0BMC Veterinary Research, Journal Year: 2024, Volume and Issue: 20(1)
Published: July 19, 2024
Abstract To evaluate Tribulus terrestris and Mucuna pruriens for inducing all-male tilapia, mixed-sex Nile Oreochromis niloticus, (mean weight 0.025 ± 0.009 g; mean length 1.25 0.012 cm) , were given a meal supplemented with either T. powder (commercial fish feed, 40% crude protein) (TT group), M. seed extract (MP MP + TT (mixed 17α-methyl testosterone (MT, control positive), or without supplements (control negative). The extracts significantly increased ( P < 0.05) the final weight, gain, gain rate, specific growth rate while feed conversion ratio was decreased 0.05). Plant markedly improved survival proportion of males, total compared to MT. Estrogen levels lower in groups plant than other groups. Fifteen days post-feeding, Amh gene expressed brain O. niloticus fries higher MP, TT, MT Additionally, expression Sox9 Dmrt1 genes as male related fry gonads revealed fed on after 30-day whereas; Foxl2 female 30 post feeding. Histologically, MT, mixture all exhibited solely reproductive traits noticeable abnormalities. This study concluded that each can induce sex reversal tilapia having no negative health impact treated group
Language: Английский
Citations
0