medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Sept. 14, 2023
Abstract
Introduction
The
COVID-19
pandemic
had
large
impacts
on
mental
health;
however,
most
existing
evidence
is
focused
the
initial
lockdown
period
and
high-income
contexts.
By
assessing
trajectories
of
health
symptoms
in
India
over
two
years,
we
aim
to
understand
effect
later
time
periods
characteristics
a
lower-middle
income
context.
Methods
We
used
data
from
Real-Time
Insights
(RTI
COVID-India)
cohort
study
(N=3,662).
covariate-adjusted
linear
regression
models
with
generalized
estimating
equations
assess
associations
between
(PHQ-4
score)
as
well
(COVID-19
cases
deaths,
government
stringency,
self-reported
financial
impact,
infection
household)
explored
modification
by
age,
gender,
rural/urban
residence.
Results
Mental
dropped
immediately
following
but
rose
again
during
delta
omicron
waves.
Associations
stages
were
stronger
for
adults
45
years
age
older
(p<0.001).
PHQ-4
scores
significantly
independently
associated
all
considered,
including
estimated
deaths
difference
0.041
SD
units;
95%
Confidence
Interval
0.030
-
0.053),
stringency
index
(0.060
0.048
0.072),
major
(0.45
0.41-0.49),
household
(0.11
0.07-0.16).
Conclusion
While
stress
largest
Indian
adults,
effects
persisted
time,
especially
among
middle-age
adults.
highlight
importance
investments
supports
services
address
consequences
cyclical
waves
infections
disease
burden
due
or
other
emerging
pandemics.
Comprehensive Psychiatry,
Journal Year:
2024,
Volume and Issue:
131, P. 152465 - 152465
Published: Feb. 17, 2024
The
COVID-19
pandemic
has
wrought
a
profound
impact
on
mental
health
in
Sub-
Saharan
Africa,
exacerbating
existing
disparities
and
rendering
individuals
undergoing
treatment
particularly
susceptible.
This
comprehensive
critical
review
delves
into
the
scope,
nature,
extent
of
services
while
concurrently
elucidating
pivotal
lessons
exemplary
practices
learnt
from
periods
lockdown.
Comprehensive Psychoneuroendocrinology,
Journal Year:
2023,
Volume and Issue:
15, P. 100186 - 100186
Published: May 18, 2023
The
COVID-19
pandemic
has
caused
significant
negative
consequences
to
mental
health.
Increased
inflammatory
factors
and
neuropsychiatric
symptoms,
such
as
cognitive
impairment
("brain
fog"),
depression,
anxiety
are
associated
with
long
COVID
[post-acute
sequelae
of
SARS-CoV-2
infection
(PASC),
termed
neuro-PASC].
present
study
sought
examine
the
role
predictors
symptom
severity
in
context
COVID-19.
Adults
(n
=
52)
who
tested
or
positive
for
were
asked
complete
self-report
questionnaires
provide
blood
samples
multiplex
immunoassays.
Participants
assessed
at
baseline
a
follow-up
visit
(∼4
weeks
later).
Individuals
without
reported
significantly
lower
PHQ-4
scores
visit,
compared
(p
0.03;
95%
CI-1.67
−0.084).
experienced
neuro-PASC
had
moderate
range.
majority
people
experiencing
brain
fog
(70%
vs.
30%).
Those
more
severe
higher
scores,
those
mild
disease
0.008;
CI
1.32
7.97).
Changes
accompanied
by
alterations
immune
factors,
particularly
monokine
induced
gamma
interferon
(IFN-γ)
(MIG,
a.
k.a.
CXCL9).
These
findings
add
growing
evidence
supporting
usefulness
circulating
MIG
levels
biomarker
reflecting
IFN-γ
production,
which
is
important
because
individuals
have
elevated
responses
internal
proteins.
BMC Psychiatry,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 18, 2025
Major
depressive
disorder
(MDD)
is
an
important
public
health
problem
among
adolescents
and
young
adults,
its
increasing
prevalence
underscores
the
need
for
region-specific
age-specific
interventions.
Despite
burden,
comprehensive
data
on
regional
longitudinal
trends
in
MDD
are
scarce.
This
study
analyzed
global,
regional,
national
incidence,
prevalence,
disability-adjusted
life
years
(DALYs)
individuals
aged
10-24
from
1990
to
2021,
while
examining
differences
by
gender,
age,
socio-demographic
factors,
emerging
risk
factors
guide
targeted
mental
strategies.
With
2021
Global
Burden
of
Disease
Study,
we
conducted
analysis
age-standardized
DALYs
due
sex,
age
group,
21
geographic
regions
with
a
special
focus
sociodemographic
index
(SDI)
levels,
which
measures
development
scale
low
high.
Key
such
as
bullying
intimate
partner
violence,
were
also
assessed
order
understand
their
contribution
burden
MDD.
Between
global
increased
substantially.
Prevalence
rose
56.36%
globally,
particularly
men
adults
20-24
years,
largest
increases
observed
Eastern
Sub-Saharan
Africa
(184.26%
increase).
Incidence
grew
56.11%,
experiencing
steepest
rise
compared
slower
other
regions.
56.32%,
greatest
Africa.
Bullying
violence
leading
contributors
across
all
childhood
sexual
abuse
MDD-related
DALYs,
peaking
at
ages
10-14,
had
higher
impact
females,
rising
sharply
after
2006.
Post-
2020,
metrics
(prevalence,
DALYs)
sharply,
high-SDI
regions,
likely
specific
impacts
COVID-
19
pandemic,
prolonged
lockdowns,
social
isolation,
disruptions
services.
highlights
culturally
sensitive
policies
focusing
prevention
early
intervention,
providing
insights
improve
resource
allocation
support
further
research
adolescent
health.
Not
applicable.
BMJ Global Health,
Journal Year:
2024,
Volume and Issue:
9(1), P. e013365 - e013365
Published: Jan. 1, 2024
The
COVID-19
pandemic
had
large
impacts
on
mental
health;
however,
most
existing
evidence
is
focused
the
initial
lockdown
period
and
high-income
contexts.
By
assessing
trajectories
of
health
symptoms
in
India
over
2
years,
we
aim
to
understand
effect
later
time
periods
characteristics
a
lower-middle
income
context.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Oct. 4, 2024
The
COVID-19
pandemic
has
left
a
profound
mark
on
global
health,
leading
to
substantial
morbidity
and
mortality
worldwide.
Beyond
the
immediate
symptoms
of
infection,
emergence
“long
COVID”,
long-term
effects
SARS-CoV-2,
become
significant
public
health
concern.
Long
COVID
is
multifaceted
condition
affecting
various
organs
systems,
including
cardiovascular,
digestive,
nervous,
endocrine
systems.
Individuals
diagnosed
with
polycystic
ovary
syndrome
(PCOS)
may
face
an
increased
risk
severe
infection.
It
crucial
comprehend
how
long
affects
PCOS
patients
devise
effective
treatment
care
strategies.
Here,
we
review
detrimental
its
reproductive
function,
inflammation,
metabolism,
cardiovascular
body
composition,
lifestyle,
mental
in
PCOS.
We
offer
recommendations
for
post-covid-19
management
PCOS,
emphasizing
necessity
comprehensive,
multidisciplinary
approach
patient
care.
Furthermore,
discuss
prospective
research
directions,
highlighting
significance
continued
investigations
clinical
trials
evaluate
approaches
ramifications
individuals
PLoS Medicine,
Journal Year:
2023,
Volume and Issue:
20(4), P. e1004224 - e1004224
Published: April 24, 2023
In
this
editorial,
guest
editors
Vikram
Patel,
Daisy
Fancourt,
Lola
Kola,
and
Toshi
Furukawa
discuss
the
contents
of
special
issue
on
pandemic
global
mental
health,
highlighting
key
themes
providing
important
context.
Children,
Journal Year:
2023,
Volume and Issue:
10(7), P. 1213 - 1213
Published: July 13, 2023
The
aim
of
this
research
was
to
evaluate
the
effects
social
determinants
(i.e.,
gender,
educational
vulnerability,
and
socioeconomic
status)
resilience
on
mental
health
Chilean
adolescents
in
pre-,
during,
post-COVID-19
pandemic
contexts.
study
included
a
group
684
students,
ranging
age
from
12
18
years,
who
were
attending
institutions
city
Arica.
Child
Adolescent
Assessment
System
(SENA)
used
measure
problems,
Brief
Resilience
Scale
for
Children
Youth
(CYRM-12)
resilience,
Vulnerability
Index
Educational
Institutions
vulnerability.
results
suggest
increases
depressive,
anxious,
anxiety
symptomatologies
over
time
(wave
by
year,
2018,
2020,
2021).
In
addition,
multiple
linear
regression
models
showed
predictive
COVID-19
pandemic,
vulnerability
index,
status,
resilient
behaviors
problems.
worsening
indicators
requires
greater
coordination
integration
experts
most
vulnerable
centers.
IJID Regions,
Journal Year:
2024,
Volume and Issue:
12, P. 100396 - 100396
Published: June 26, 2024
Outbreaks
are
associated
with
increased
risk
of
anxiety
disorders,
depression,
and
severe
mental
conditions.
Integrating
health
psychosocial
support
(MHPSS)
into
outbreak
response
facilitates
the
delivery
holistic
care
to
affected
community.
As
there
is
an
increasing
incidence
outbreaks
globally,
integrating
MHPSS
preparedness
plans
paramount
strengthen
capacity
existing
systems
respond
needs.
However,
attention
given
during
critically
low.
The
objectives
this
study
were
identify
areas
integration
explore
challenges
that
hinder
integrated
response.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Oct. 28, 2024
This
study
examined
the
relation
between
pandemic-related
stressors
and
mental
health
among
young
people
(YP)
in
India
during
two
time
points
waning
phase
of
pandemic.
We
use
data
from
cross-sectional
waves
over
20,000
YP
aged
5–19
February
2022,
peak
Omicron
wave,
October
a
reduction
infections
easing
restrictions.
COVID
illness/death
family's
social
network,
current
lockdown
stringency,
significant
change
household
income
were
to
adult
respondents'
reports
internalizing
symptoms.
Internalizing
symptoms
declined
slightly
2022.
COVID-19
network
was
generally
associated
with
more
Higher
stringency
lower
levels
households
increases
tended
have
Many
associations
driven
by
older
adolescents
stronger
earlier
(Feb-2022)
than
later
(Oct-2022)
collection
time-points.
The
findings
illustrate
importance
anchoring
results
within
study's
specific
geographic
context,
including
concurrent
events
period.
Importantly,
that
may
initially
seem
counterintuitive
ultimately
illuminate
dynamic
complex
processes
underlying
child
adolescent
health.
Clinical Gerontologist,
Journal Year:
2023,
Volume and Issue:
unknown, P. 1 - 11
Published: Nov. 3, 2023
Many
older
adults
in
Colombia
have
lived
through
violent
and
stressful
life
events,
particularly
areas
of
poverty.
The
aim
this
qualitative
study
was
to
understand
the
impact
events
on
mental
health
wellbeing
Colombians
living
relative
poverty.Older
(aged
60+)
Turbo
region
were
interviewed
face-to-face
between
August
December
2021.
Transcripts
coded
Spanish
English
by
at
least
two
researchers,
using
inductive
thematic
analysis.Twenty-six
participated
study.
Four
overarching
themes
generated:
Living
dangerous
communities;
Disturbing
gender
violence
roles;
Lack
awareness;
Coping
mechanisms.
Older
experienced
a
long
narrative
events.
Younger
generations
appeared
disrespect
members
Society.
Without
any
support,
coped
accepting
extreme
situations
or
seeking
solace
their
faith.The
system
Government
need
build
up
trust
generate
an
awareness
health,
as
will
not
approach
psychological
support
otherwise.
Intergenerational
community-based
interventions
may
provide
first
avenue
support.