Predictors and incidence of depression and anxiety in women undergoing infertility treatment: A cross-sectional study

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(4), P. e0284414 - e0284414

Published: April 13, 2023

The global incidence of infertility is increasing year by year, and the association between mental illness has been widely concerned. aim this study was to investigate anxiety depression in infertile women China explore risk factors which might lead depression. From January 2020 December 2020, female patients who received assisted reproduction technology (ART) treatment at West Second Hospital were recruited a total 1712 eligible finally enrolled study. Generalized Anxiety Disorder-7 (GAD-7) Patient Health Questionaire-9 (PHQ-9) used evaluate patients' psychological status. reliability all scales evaluated Cronbach's α Spearman-Brown half coefficient, Kaiser-Meyer-Olkin (KMO) value calculated factor analysis validity. Univariate multivariate logistic regression applied for assessing independent depression, respectively. 25.2% 31.3%, coefficients half-fold GAD-7 PHQ-9 0.870, 0.825, 0.852 0.793, showed that education level (junior college degree or above, OR:1. 6, 95% CI: 1.2-2.1, P = 0.003), somatic symptoms (severe symptoms, OR:15.2, 95%CI: 5.6-41.3, P<0.001), sleep quality (poor quality, OR:9.3, CI:4.7-18.4, P<0.001) anxiety. And age>35 years old, moderate severe poor Somatic are both woman. high educated above) more likely be complicated with while elderly (age>35) prone symptoms.

Language: Английский

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The definition of treatment resistance in anxiety disorders: a Delphi method‐based consensus guideline

World Psychiatry, Journal Year: 2024, Volume and Issue: 23(1), P. 113 - 123

Published: Jan. 12, 2024

Anxiety disorders are very prevalent and often persistent mental disorders, with a considerable rate of treatment resistance which requires regulatory clinical trials innovative therapeutic interventions. However, an explicit definition treatment-resistant anxiety (TR-AD) informing such is currently lacking. We used Delphi method-based consensus approach to provide internationally agreed, consistent clinically useful operational criteria for TR-AD in adults. Following summary the current state knowledge based on international guidelines available systematic review, survey free-text responses 29-item questionnaire relevant aspects TR-AD, online meeting, panel 36 multidisciplinary experts stakeholders voted anonymously written statements three rounds. Consensus was defined as ≥75% agreeing statement. The agreed set 14 recommendations providing detailed pharmacological and/or psychotherapeutic treatment, well potential staging model. also evaluated further regarding epidemiological subgroups, comorbidities biographical factors, terminology vs. "difficult-to-treat" preferences attitudes persons these future research directions. This expected serve systematic, practical guideline aid designing mechanistic studies facilitate purposes. effort could ultimately lead development more effective evidence-based stepped-care algorithms patients disorders.

Language: Английский

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Anxiety Symptoms in Patients with Major Depressive Disorder: Commentary on Prevalence and Clinical Implications

Neurology and Therapy, Journal Year: 2023, Volume and Issue: 12(S1), P. 5 - 12

Published: April 1, 2023

The prevalence of major depressive disorder (MDD) has been increasing, and MDD is now a leading cause global disability. Depression often coexists with anxiety, the 5th edition Diagnostic Statistical Manual Mental Disorders (DSM-5) introduced 'anxious distress' specifier to identify those patients within category who have anxiety as well. anxious depression high, studies suggesting that 50–75% meet DSM-5 criteria for depression. However, it can be difficult discern whether patient or an triggered episode In fact, approximately 60–70% comorbid experience first, but leads seek treatment. Patients also significantly worse psychosocial functioning poorer quality life compared without anxiety. addition, take longer achieve remission, are less likely than Therefore, essential physicians high index suspicion in depression, symptoms effectively treated. This commentary based on virtual symposium presented at 33rd International College Neuropsychopharmacology (CINP) World Congress, Taipei, Taiwan, June 2022.

Language: Английский

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Factorial invariance of the generalized anxiety disorder scale (GAD-7) in Latin America and the Caribbean

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 30, 2025

Introduction The prevalence of Generalized Anxiety Disorder (GAD) has increased rapidly, highlighting the importance its detection using quick tools applicable to men and women from different countries. Objective To analyze psychometric properties Test (GAD-7) by gender country in Latin America Caribbean (LAC). Method A cross-sectional e-health study with 12,124 participants 15 LAC countries (54.32% women, 45.68% men) was conducted, including Argentina (7.3%), Bolivia (6.7%), Colombia (10.3%), Chile (6.9%), Costa Rica (4.9%), El Salvador (5.7%), Ecuador (7.2%), Guatemala (4.7%), Panama (5.1%), Paraguay Peru (8.6%), Puerto Rico (5.8%), Dominican Republic (6.6%), Uruguay (6.3%), Venezuela (8.2%). All completed GAD-7 scale digitally. Results unidimensional structure confirmed, explaining 70% variance. model fit indices were adequate (RMSEA = 0.062; CFI 0.997; TLI 0.995; SRMR 0.017; p &lt; 0.001), factor loadings for each item satisfactory (&gt; 0.70). Additionally, showed measurement invariance between genders countries, at all levels (configural, metric, scalar, strict), suggesting that measurements are equivalent both contexts. Finally, internal consistency high, a McDonald’s Omega coefficient 0.91. Conclusions exhibits is across demonstrating validity reliability rapid GAD symptoms within region.

Language: Английский

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Depressive symptomatology in Brazil: perspectives of statistical and psychometrics analyses of the PHQ-9 at four time-points (2020–2023) in the COVID-19 pandemic

Frontiers in Psychology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 5, 2025

The present research assessed the psychometric properties of Patient Health Questionnaire-9 (PHQ-9) through an examination its internal structure, invariance analysis, and standardization. Social distribution analyses measure were conducted using linear binomial logistic regression. sample consisted 10,069 adults from all 27 states in Brazil. data obtained four collections across different years COVID-19 pandemic (2020, 2021, 2022, 2023), independent samples. Confirmatory Factor Analysis (CFA) indicated that is unidimensional with satisfactory fit indices. model was invariant relation to variables investigated at levels (configural, metric, scalar, strict). standardization supported hypothetical cut scores indicating severity depressive symptoms, categorized as very low (0 6), (7 13), moderate (14 19), high (20 23), (≥ 24). We found sex/gender, skin color/ethnicity, age, education level, year predictors symptoms adjusted regression analysis. showed higher chances for a positive screening diagnosis depression, Odds Ratio follows: 2021 (OR adj = 1.275) 2023 1.409), women 1.900), Pardos individuals 1.252), up school 1.272), being northeast region resident 2.127), younger people 1.716). findings this study indicate suitability PHQ-9 assessing depression population recommend use monitoring coming Clinical implications include developing interventions address psychological impact any future health crises.

Language: Английский

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Psychometric properties of the patient health questionnaire-8 and general anxiety disorder-7 in adolescents and young adults from three Latin American cities: Internal structure, invariance, internal consistency and divergent validity

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 378, P. 138 - 146

Published: Feb. 26, 2025

Language: Английский

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Estradiol is Pro-Nociceptive and Associated with a Small-Fiber Neuropathy Among Premenopausal Women with Sickle Cell Disease

Hemoglobin, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: April 14, 2025

Vaso-occlusive crisis (VOC) pain episodes often occur with menses and concurrent hormonal contraceptive use may reduce their frequency. This study tested the hypothesis that among women sickle cell disease (SCD), sex hormones are associated detection thresholds. Women SCD aged minimum 18 years regular menses, without acute illnesses, pregnancy, oophorectomy, or within three months prior were included. Pain thresholds for heat (HPT) pressure (PPT), serum estradiol, progesterone testosterone measured at follicular luteal phases. The Adult Sickle Cell Quality-of-Life Measurement Information System assessed quality-of-life VOC frequency severity scores. Generalized linear mixed models performed, including day of cycle standardized by length. Among 125 participants, neither nor phase menstrual was PPT HPT. In multivariate analyses, worse scores (β = 1.7) severe genotype -46.0) higher lower trapezius PPT, respectively. Older age forearm HPT -0.1). leg measurements, ovulatory cycles -1.1) hydroxyurea -1.2) HPT, while 0.1) Higher estradiol -0.02), an interaction 0.001) predicting earlier in same level. Estradiol is a time-varying, length-dependent small-fiber neuropathy women; be potential therapeutic target biomarker pain.

Language: Английский

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Burden of Common Mental Disorders in Ulcerative Colitis and Irritable Bowel Syndrome Patients: An Analysis of Risk Factors

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 499 - 499

Published: Jan. 14, 2025

Background: Common mental disorders are an underdiagnosed comorbidity, which can significantly worsen the prognosis of main disease and decrease quality life. We aimed to investigate prevalence depression anxiety in a cohort irritable bowel syndrome with diarrhea (IBS-D) ulcerative colitis (UC) patients evaluate risk factors for their occurrence. Materials Methods: A total 112 were evaluated. Multivariable analysis was used determine associations between patient common disorders, evaluated PHQ-9 GAD-7 questionnaires. Results: found higher moderate severe among IBS-D, when compared UC group (p < 0.01). Linear regression revealed inverse association anti-TNF-alpha monoclonal antibodies treatment score = 0.02). Multivariate that, UC, presence children has been associated 0.01), both individually combination duration disease. For active employment status religious belief, educational level, as well belief correlated scores 0.03, p 0.03 0.02, respectively). Conclusions: Infliximab improved parameters depression. Patients who have university education longer at increased developing anxiety, especially if they care. Regarding IBS-D work status, beliefs caregivers anxiety.

Language: Английский

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A Deep Learning-Based Technique for Detection of Generalized Anxiety Disorder using CNN and ResNet-like Approach

Arabian Journal for Science and Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Language: Английский

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Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults

Cochrane library, Journal Year: 2025, Volume and Issue: 2025(3)

Published: March 25, 2025

Language: Английский

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