Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

Vaccines, Journal Year: 2022, Volume and Issue: 10(8), P. 1356 - 1356

Published: Aug. 19, 2022

Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who hesitant to receive the vaccine. Studies assessing factors associated with hesitancy inconclusive. This study aimed assess global prevalence of and determine potential such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, Web Science. Extraction required information was each study. A single-arm meta-analysis hesitancy; related vaccine were analyzed using a Z-test. total 56 included our analysis. found that 25%. Being woman, being 50-year-old or younger, single, unemployed, living household five more individuals, having educational attainment lower than undergraduate degree, non-healthcare-related job considering vaccines be unsafe higher risk In contrast, children at home, maintaining physical distancing norms, ever tested COVID-19, history influenza past few years vaccination. Our provides valuable on hesitancy, we recommend special interventions sub-populations increased reduce

Language: Английский

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Coronavirus Disease 2019 (COVID-19) Pandemic across Africa: Current Status of Vaccinations and Implications for the Future

Vaccines, Journal Year: 2022, Volume and Issue: 10(9), P. 1553 - 1553

Published: Sept. 17, 2022

The introduction of effective vaccines in December 2020 marked a significant step forward the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is need describe current status vaccine uptake continent. An exploratory study was undertaken investigate these aspects, challenges, lessons learnt Africa provide future direction. Senior personnel 14 African countries completed self-administered questionnaire, descriptive analysis data. Vaccine roll-out commenced March 2021 most countries. COVID-19 vaccination coverage varied from low Cameroon Tanzania up 39.85% full Botswana at end 2021; that is, all doses advocated by initial protocols versus total population, rates increasing 58.4% June 2022. greatest increase people being fully vaccinated observed Uganda (20.4% increase), (18.5% Zambia (17.9% increase). Most were obtained through WHO-COVAX agreements. Initially, prioritised for healthcare workers (HCWs), elderly, adults co-morbidities, other at-risk groups, now commencing among children administering booster doses. Challenges included irregular supply considerable arising misinformation fuelled social media activities. Overall, fair reasonable access countries, enhanced government initiatives. must be addressed context-specific interventions, including proactive programmes HCWs, medical journalists, public.

Language: Английский

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Knowledge, attitude and acceptability of COVID-19 vaccine among residents in rural communities in Ghana: a multi-regional study

BMC Infectious Diseases, Journal Year: 2023, Volume and Issue: 23(1)

Published: Jan. 31, 2023

Abstract Background The Coronavirus Infectious Disease 2019 (COVID-19) pandemic has continuously affected human life with several devastating effects. Currently, there are effective vaccines to protect people from COVID‐19 and the World Health Organization (WHO) highlighted strategies influence COVID-19 vaccine uptake in hard-to-reach communities Ghana. However, prior studies on acceptability Ghana online surveys targeting literates those urban areas, leaving residents far-flung communities. We assessed knowledge, attitude of among rural Methods This study was a community-based cross-sectional conducted at three selected regions (Northern, Ashanti Western North) May November, 2021. included 15–81 years, living for more than 1 year. Study participants were recruited questionnaires administered collect data acceptance vaccine. Statistical analyses performed using Package Social Science (SPSS) version 26.0 GraphPad Prism Version 8.0 software. Results Of 764 this study, half had inadequate knowledge (55.0%), poor attitudes (59.4%) bad perception about (55.4%). 41.9%. Ashanti, Northern North 32.5%, 26.2% 29.6% respectively. In multivariate logistic regression analysis, receiving recent or previous such as HBV [aOR = 1.57, 95% CI (1.23–3.29), p 0.002], having good towards 61.47, (29.55–127.86), < 0.0001] 3.87, (1.40–10.72), independently associated higher odds accepting Conclusion More Ghanaian have is generally low Residents must be educated benefits achieve vaccination program.

Language: Английский

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Persisting Vaccine Hesitancy in Africa: The Whys, Global Public Health Consequences and Ways-Out—COVID-19 Vaccination Acceptance Rates as Case-in-Point

Vaccines, Journal Year: 2022, Volume and Issue: 10(11), P. 1934 - 1934

Published: Nov. 15, 2022

Vaccine hesitancy (VH) is the seventh among WHO’s top 10 threats to global public health, which has continued perpetuate transmission of vaccine preventable diseases (VPDs) in Africa. Consequently, this paper systematically reviewed COVID-19 acceptance rates (VARs)—including uptake and vaccination intention—in Africa from 2020 2022, compared within five African regions determined context-specific causes VH Generally, VARs ranged 21.0% 97.9% 8.2% 92.0% with mean 59.8 ± 3.8% 58.0 2.4% 2021 respectively. Southern eastern had two 83.5 6.3% 68.9 6.6% 2021, 64.2 4.6% 61.2 5.1% Based on population types, healthcare workers a marginal increase their 55.5 5.6% 60.8 5.3% 2022. In other populations, decreased 62.7 5.2% 54.5 4% As 25 October lags behind world only 24% full vaccinations 84%, 79% 63% reported, respectively, Australian continent, upper-middle-income countries globally. Apart problems confidence, complacency, convenience, communications context, factors driving are inequality, lack production/maintenance facilities, insecurity, high illiteracy level, endemic corruption, mistrust some political leaders, spreading unconfirmed anti-vaccination rumors instability. With an overall rate 58%, still subsists The low have detrimental health implications, as it could facilitate emergence immune invading SARS-CoV-2 variants concern, may spread there need confront these challenges frontally engage traditional religious leaders fight against Africa, restore trust safety efficacy vaccines generally. availability improves, pets zoo-animals reverse zoonotic been reported recommended, limit evolution new concern avert possible epizootic or panzootic susceptible animal species.

Language: Английский

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COVID-19 Vaccine Hesitancy among Healthcare Workers and Trainees in Freetown, Sierra Leone: A Cross-Sectional Study

Vaccines, Journal Year: 2022, Volume and Issue: 10(5), P. 757 - 757

Published: May 11, 2022

Despite having safe and efficacious vaccines against COVID-19, vaccine hesitancy is widespread. Although a trusted source of information, has been reported among healthcare professionals, yet few studies have explored this phenomenon in sub-Saharan Africa. We conducted cross-sectional survey professionals Sierra Leone from January to March 2022. Measures included sociodemographic/health-related information COVID-19-related concerns. From the responses, we constructed (VAX) score, with higher scores implying negative attitudes or unwillingness vaccinate. Multivariate linear regression was used access factors associated hesitancy. Overall, 592 participants submitted responses (67.2% female, mean age 29 years, 5.6% physicians/pharmacists, 44.3% medical students, 29.2% nurses, 20.9% nursing students). The VAX score 43.27 ± 8.77, 60.1% respondents classified as hesitant (>50th percentile) 13.8% highly (>75th percentile). Worries about unforeseen future effects (76.3%), preference for natural immunity (59.5%), profiteering/mistrust health authorities (53.1%) were most common Being student (β = 0.105, p 0.011) previously refusing recommended 0.177, < 0.001) predictors COVID-19 Our findings call addressing an essential component strategies aimed at increasing uptake setting.

Language: Английский

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Global COVID-19 vaccine acceptance rate: Systematic review and meta-analysis

Frontiers in Public Health, Journal Year: 2022, Volume and Issue: 10

Published: Dec. 8, 2022

A vaccine against COVID-19 is a vital tool in managing the current pandemic. It becoming evident that an effective would be required to control COVID-19. Effective use of vaccines very important controlling pandemics and paving way for acceptable exit strategy. Therefore, this systematic review meta-analysis aims determine global acceptance rate necessary better management

Language: Английский

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COVID-19 vaccine acceptance and associated factors in 13 African countries: A systematic review and meta-analysis

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 10

Published: Jan. 24, 2023

Background The COVID-19 pandemic has severely affected the entire world, especially sub-Saharan Africa. As a result, researchers and government agencies are working to create effective vaccinations. While vaccination campaigns moving rapidly in high-income nations, is still ruthlessly affecting people low-income nations. However, this difference spread of disease not because lack vaccine but mainly due people's reluctance. review summarized data on adoption factors related among nations Method Comprehensive searches were conducted using PubMed, Embase, Medline, Web Science, Google Scholar, Cochrane Library databases. risk bias methodological quality each published article that fit selection criteria evaluated Critical Appraisal Checklist tools. All statistical analysis was done by STATA 16. Results This based 29 studies with 26,255 participants from Using random-effects model, pooled prevalence acceptance study 55.04% (95 % CI: 47.80–62.27 %), I 2 = 99.55%. Being male [POR 1.88 (95% 1.45, 2.44)], having positive attitude toward 5.56 3.63, 8.51)], good knowledge 4.61 1.24, 8.75)], trust 7.10 2.37, 21.32)], undergone testing past 4.41 (95%CI: (2.51, 7.75)] significant predictor variables. Conclusion showed respondents had decreased acceptance. Sex, attitude, knowledge, trust, statistically significantly correlated characteristics acceptability vaccine. stakeholders should be actively involved increasing uptake thereby reducing consequences COVID-19. can increased conclusion as an indicator for governments, healthcare professionals, health policymakers their work testing.

Language: Английский

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Factors Driving COVID-19 Vaccine Hesitancy in Cameroon and Their Implications for Africa: A Comparison of Two Cross-Sectional Studies Conducted 19 Months Apart in 2020 and 2022

Vaccines, Journal Year: 2022, Volume and Issue: 10(9), P. 1401 - 1401

Published: Aug. 26, 2022

Many efficacious COVID-19 vaccines have been approved for general use but their ability to control the disease is being undermined by slow uptake. Resources are needed persuade people obtain a vaccine. Here we compare this present study and previous one assess impact of Cameroon government's policy efforts reduce vaccine hesitancy after year implementation. After obtaining ethical clearance informed consent, 6732 participants completed questionnaire about acceptance. It was observed that policies reduced significantly, not enough ensure herd immunity necessary disease. The risk factors associated with were consumption traditional herbal remedies; living in an urban setting; female, jobless or student; working education sector; politician/policy maker/administrator, engineer technician; medium income; no education/primary school/secondary/high school/professional training; informal sector. In contrast, who male, healthcare personnel, high-income earners, do consume remedies, infected knowing someone has COVID-19, having chronic illness comorbidity, Participants also gave several reasons they either hesitant willing take A more rigorous surveillance system systematically monitor drivers hesitancy, establish tailored interventions promoting acceptance, evaluate these interventions.

Language: Английский

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Novel COVID-19 vaccine hesitancy and acceptance, and associated factors, amongst medical students: a scoping review

Medical Education Online, Journal Year: 2023, Volume and Issue: 28(1)

Published: Feb. 14, 2023

Medical students are likely to be exposed COVID‐19 patients so achieving high vaccination coverage rates for this group of healthcare workers is important, as their potential role models. The aim scoping review was evaluate the current literature determine COVID-19 vaccine hesitancy and acceptance, associated factors, amongst medical students. Systematic searches Medline Ovid, Embase, PubMed, Education Resources Information Centre (ERIC) online databases conducted relevant articles with keywords: 'COVID-19', 'vaccine & acceptance' 'medical students'. Articles were included if they reported Of 258 identified, 52 met inclusion criteria underwent full-text review. Rates ranged from 5.4−86.7%, generally positive attitudes towards vaccination. main factors concerns about safety efficacy vaccines due accelerated development, being a pre-clinical student, low perceived personal risk infection. Inconsistencies found influence gender on vaccinations. Previous behaviours predictive willingness receive vaccine. Knowledge vaccinations importance deficient hesitant Generally, express levels hesitancy. However, variability in across different populations dynamic contextual nature hesitancy, it recommended that intent monitored longitudinal basis. It important map at local level allow schools develop strategies encourage specific school's needs.

Language: Английский

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Evaluation of Conspiracy Beliefs, Vaccine Hesitancy, and Willingness to Pay towards COVID-19 Vaccines in Six Countries from Asian and African Regions: A Large Multinational Analysis

Vaccines, Journal Year: 2022, Volume and Issue: 10(11), P. 1866 - 1866

Published: Nov. 4, 2022

Vaccination protects people from serious illness and associated complications. Conspiracy theories misinformation on vaccines have been rampant during the COVID-19 pandemic are considered significant drivers of vaccine hesitancy. Since hesitancy can undermine efforts to immunize population against interferes with vaccination rate, this study aimed ascertain COVID-19-vaccine-related conspiracy beliefs, hesitancy, views regarding mandates, willingness pay for among general population. A web-based, cross-sectional survey was conducted (April–August 2021) adult in six countries (Pakistan, Saudi Arabia, India, Malaysia, Sudan, Egypt). Participants were recruited using an exponential, non-discriminate snowball sampling method. validated self-completed electronic questionnaire used data collection. All participants responded questions various domains instrument, including pay. The responses scored according predefined criteria stratified into groups. entered analyzed SPSS version 22. total 2481 included (Pakistan 24.1%, Arabia 19.5%, India 11.6%, Malaysia 8.1%, Sudan 19.3%, Egypt 17.3%). There a preponderance ≤40 years old (18–25 years: 55.8%, 26–40 28.5%) females (57.1%). average score belief scale (C19V-CBS) 2.30 ± 2.12 (median 2; range 0–7). Our analysis showed that 30% respondents found achieve ideal zero, indicating no belief. mean (C19V-HS) 25.93 8.11 (range: 10–50). majority (45.7%) had C19V-HA scores 21–30 nearly 28% achieved greater than 30, higher degree positive correlation between beliefs (Spearman’s rho = 0.547, p < 0.001). Half mandate. Respondents favor governmental enforcement significantly (p 0.001) lower C19V-CBS C19V-HS scale. Nearly 52% reported they would only take if it free, 24% willing vaccines. high prevalence observed targeted countries. findings highlight dire need aggressive measures counter factors underlying

Language: Английский

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