Health and social service provider perspectives on challenges, approaches, and recommendations for treating long COVID: a qualitative study of Canadian provider experiences DOI Creative Commons

Anh T. P. Nguyen,

Chantal F. Ski, David R. Thompson

et al.

BMC Health Services Research, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 8, 2025

Many people who contract the SAR-CoV-2 virus present with multiple persistent and debilitating physical, cognitive mental health symptoms that endure beyond acute infection period. This new syndrome - generally referred to as long COVID negatively affects patients' emotional wellbeing quality of life, presents a major challenge for treatment providers. Considering lack evidence-based supports, this qualitative descriptive study explores experiences Canadian social service providers working individuals COVID, well their suggestions intervention development. Twenty between ages 29 57 across Canada completed virtual individual interviews discuss care recommendations COVID. Participants were from range sectors, including primary care, rehabilitation, health, community support. Interviews recorded, transcribed, analyzed using codebook thematic analysis. Four themes illustrated providers' (1) selecting personalized treatments based on patient presentation similar conditions amidst uncertainty; services, (2) building an integrated model care; (3) providing holistic support patients families through psychoeducation daily living resources; (4) caring in are adopting approaches address symptom persistence face considerable knowledge gap. A comprehensive, pathway is needed physical psychosocial while increasing provider preparedness treat complex condition.

Language: Английский

Long COVID science, research and policy DOI Creative Commons
Ziyad Al‐Aly, Hannah Davis, Lisa McCorkell

et al.

Nature Medicine, Journal Year: 2024, Volume and Issue: 30(8), P. 2148 - 2164

Published: Aug. 1, 2024

Long COVID represents the constellation of post-acute and long-term health effects caused by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every organ system be severely disabling. The cumulative global incidence long around 400 million individuals, which estimated to have an annual economic impact approximately $1 trillion-equivalent about 1% economy. Several mechanistic pathways are implicated in COVID, including viral persistence, immune dysregulation, mitochondrial dysfunction, complement endothelial inflammation microbiome dysbiosis. devastating impacts on individual lives and, due its complexity prevalence, also has major ramifications for systems economies, even threatening progress toward achieving Sustainable Development Goals. Addressing challenge requires ambitious coordinated-but so far absent-global research policy response strategy. In this interdisciplinary review, we provide synthesis state scientific evidence assess human health, systems, economy metrics, forward-looking roadmap.

Language: Английский

Citations

138
The lived experience of long COVID: A qualitative study of mental health, quality of life, and coping DOI Creative Commons

C Kennelly,

Anh T. P. Nguyen,

Natasha Y. Sheikhan

et al.

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(10), P. e0292630 - e0292630

Published: Oct. 13, 2023

The majority of people who contract COVID-19 experience a short period symptomatic infection. However, symptoms persist for months or years following initial exposure to the virus in some cases. This has been described as long COVID. Little is known about lived this condition, it only recently emerged. study aimed explore experiences mental health, quality life, and coping among living with A sample 47 adults participated web-based focus groups. Separate groups were held 24 individuals pre-existing health conditions 23 without conditions. Data analyzed using codebook thematic analysis approach. Five themes identified integral COVID experience: Emotional Landscape Long COVID, New Limits Daily Functioning, Grief Loss Former Identity, COVID-related Stigmatization, Learning Cope Persisting Symptoms. These findings illustrate immense impact on life. Minimal differences found between those conditions, both substantially impacted by condition. Attention perspectives necessary inform future directions research clinical practice.

Language: Английский

Citations

24
Explaining Long COVID: A Pioneer Cross-Sectional Study Supporting the Endocrine Hypothesis DOI Creative Commons
Taïeb Ach,

Nassim Ben Haj Slama,

Asma Gorchane

et al.

Journal of the Endocrine Society, Journal Year: 2024, Volume and Issue: 8(3)

Published: Jan. 10, 2024

Abstract Context In some patients, symptoms may persist after COVID-19, defined as long COVID. Its pathogenesis is still debated and many hypotheses have been raised. Objective Our primary objective was to evaluate the corticotroph somatotroph functions of patients previously infected with SARS-CoV-2 experiencing post–COVID-19 syndrome detect any deficiencies that explain Methods A cross-sectional study conducted including who had contracted a postinfection period 3 months or less 15 months, divided into 2 groups. The first group (G1) comprised fully recovered while second (G2) included outcome comparison functions. Results total 64 were groups, each consisting 32 patients. G2 exhibited more frequently anterior pituitary deficits compared G1 (P = .045): for axis (G1: 6.3% vs G2: 28.1%) 31.3% 59.4%). Baseline cortisol level significantly lower in 13.37 µg/dL 11.59 µg/dL) .045). peak also 23.60 19.14 .01). For axis, insulin growth factor-1 146.03 ng/mL 132.25 ng/mL) .369). hormone 4.82 2.89 .041). Conclusion results showed COVID our cohort likely deficiencies. endocrine hypothesis involving insufficiency can be considered

Language: Английский

Citations

15
Cognitive dysfunction after covid-19 DOI Creative Commons
Emma Ladds, Julie Darbyshire, Nawar Diar Bakerly

et al.

BMJ, Journal Year: 2024, Volume and Issue: unknown, P. e075387 - e075387

Published: Feb. 1, 2024

Language: Английский

Citations

15
Return-to-work with long COVID: An Episodic Disability and Total Worker Health® analysis DOI
Elisabeth Stelson, Devanshi Dash, Lisa McCorkell

et al.

Social Science & Medicine, Journal Year: 2023, Volume and Issue: 338, P. 116336 - 116336

Published: Oct. 20, 2023

Language: Английский

Citations

21
Post-COVID-19 Syndrome in Non-Hospitalized Individuals: Healthcare Situation 2 Years after SARS-CoV-2 Infection DOI Creative Commons
Inge Kirchberger, Christa Meisinger, Tobias Dominik Warm

et al.

Viruses, Journal Year: 2023, Volume and Issue: 15(6), P. 1326 - 1326

Published: June 5, 2023

Although “post-COVID-19 syndrome” (PCS) is reported to be common even in non-hospitalized individuals, long-term information on symptom burden, healthcare needs, utilization, and satisfaction with scarce. The objectives of this study were describe utilization experiences the offered for PCS a German sample persons 2 years after SARS-CoV-2 infection. Individuals past COVID-19 confirmed by positive polymerase chain reaction testing examined at University Hospital Augsburg from 4 November 2020 26 May 2021 completed postal questionnaire between 14 June 2022 1 2022. Participants who self-reported presence fatigue, dyspnea exertion, memory problems or concentration classified as having PCS. Of 304 participants (58.2% female, median age 53.5), 210 (69.1%) had Among these, 18.8% slight moderate functional limitations. showed significantly higher large proportion complained about lacking persistent symptoms finding competent providers. results indicate need optimize patient PCS, facilitate access specialized providers, provide treatment options primary care setting improve education

Language: Английский

Citations

19
Disparities by Social Determinants of Health: Links Between Long COVID and Cardiovascular Disease DOI Creative Commons
Amitava Banerjee

Canadian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 40(6), P. 1123 - 1134

Published: Feb. 28, 2024

Long COVID has been defined by World Health Organization as "continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection, with these lasting for at least 2 no other explanation". Cardiovascular disease is implicated a risk factor, concomitant condition and consequence COVID. As well heterogeneity in definition, presentation likely underlying pathophysiology COVID, disparities social determinants health, extensively studied described cardiovascular disease, have observed three ways. First, long-term conditions, such its factors, are associated incidence severity previously socioeconomic factors important exacerbating Second, management COVID-19 may themselves lead to distal Third, there way that diagnosed, managed prevented. Together, age, sex, deprivation ethnicity far-reaching implications this post-viral syndrome across spectrum. There similarities differences compared disease. Some fact, inequalities, i.e. rather than simply variations, they represent injustices costs individuals, communities economies. In review current literature, I consider opportunities prevent, least, attenuate special challenges research, clinical practice, public health policy which evolving.

Language: Английский

Citations

8
Illness presentation and quality of life in myalgic encephalomyelitis/chronic fatigue syndrome and post COVID-19 condition: a pilot Australian cross-sectional study DOI Creative Commons
Breanna Weigel, Natalie Eaton-Fitch, Kiran Thapaliya

et al.

Quality of Life Research, Journal Year: 2024, Volume and Issue: 33(9), P. 2489 - 2507

Published: July 3, 2024

Abstract Purpose Post COVID-19 Condition (PCC), being persistent symptoms, is reminiscent of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)—a chronic multi-systemic illness characterised by neurocognitive, autonomic, endocrinological and immunological disturbances. This novel cross-sectional investigation aims to: (1) compare symptoms among people with ME/CFS (pwME/CFS) PCC (pwPCC) to inform developing diagnostic criteria; (2) health outcomes between patients without acute or (controls) highlight the burdens PCC. Methods Sociodemographic outcome data were collected from n = 61 pwME/CFS, 31 pwPCC 54 controls via validated, self-administered questionnaires, including 36-Item Short-Form Health Survey version 2 (SF-36v2) World Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). PwME/CFS also provided self-reported severity frequency derived Canadian International Consensus Criteria for case definition Results Both cohorts similarly experienced key symptoms. Few differences in observed, memory disturbances, muscle weakness, lymphadenopathy nausea more prevalent, light-headedness severe, unrefreshed sleep frequent, heart palpitations less frequent pwME/CFS (all p < 0.05). The participants’ SF-36v2 WHODAS scores comparable > 0.05); however, both returned significantly lower all domains when compared 0.001). Conclusion Australian-first demonstrates congruent debilitating nature PCC, thereby emphasising need multidisciplinary care maximise patient outcomes.

Language: Английский

Citations

8
Long COVID among healthcare workers: a narrative review of definitions, prevalence, symptoms, risk factors and impacts DOI Creative Commons
Brendan Dempsey, Ira Madan, Sharon A. M. Stevelink

et al.

British Medical Bulletin, Journal Year: 2024, Volume and Issue: 151(1), P. 16 - 35

Published: Aug. 25, 2024

Long COVID (LC) occurs when people experience symptoms for weeks, months or even years after a COVID-19 infection. This review looks at research exploring the LC definitions, prevalence, symptoms, risk factors, and associated impacts in on healthcare workers (HCWs).

Language: Английский

Citations

8
Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review DOI Creative Commons
Julian Gutzeit, Mark A. Weiss, Carolin Nürnberger

et al.

European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: July 25, 2024

Abstract Post-COVID syndrome (PCS) describes a persistent complex of symptoms following COVID-19 episode, lasting at least 4 to 12 weeks, depending on the specific criteria used for its definition. It is often associated with moderate severe impairments daily life and represents major burden many people worldwide. However, especially during first two years pandemic, therapeutic diagnostic uncertainties were prominent due novelty disease non-specific definitions that overlooked functional deficits lacked objective assessment. The present work comprehensively examines status PCS as depicted in recent reviews meta-analyses, alongside exploring impairments. We searched database Pubmed meta-analysis evaluating period between May 31, 2022, December 2023. Out 95 studies, 33 selected inclusion our analyses. Furthermore, we extended upon prior research by systematically recording linked identified studies. found fatigue, neurological complaints, exercise intolerance most frequently reported symptoms. In conclusion, over past eighteen months, there has been notable increase quantity quality studies PCS. still remains clear need improvement, particularly regard definition necessary diagnosing this syndrome. Enhancing aspect will render future more comparable precise, thereby advancing understanding

Language: Английский

Citations

7