Natural antioxidants from some fruits, seeds, foods, natural products, and associated health benefits: An update

Food Science & Nutrition, Journal Year: 2023, Volume and Issue: 11(4), P. 1657 - 1670

Published: Jan. 13, 2023

Abstract Antioxidants are compounds that inhibit the oxidation of other molecules and protect body from effects free radicals, produced either by normal cell metabolism or as an effect pollution exposure to external factors responsible for premature aging play a role in cardiovascular disease. degenerative diseases such cataracts, Alzheimer's disease, cancer. While many antioxidants found nature, others obtained synthetic form reduce oxidative stress organisms. This review highlights pharmacological relevance fruits, plants, natural sources their beneficial on human health through analysis in‐depth discussion studies included phytochemistry effects. The information this was collected several scientific databases (ScienceDirect, TRIP database, PubMed/Medline, Scopus, Web Science), professional websites, traditional medicine books. Current evidence have shown various present some seeds, foods, products different health‐promoting Adopting functional foods with high antioxidant potential will improve effective affordable management radical while avoiding toxicities unwanted side caused conventional medication.

Language: Английский

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Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation

Journal of Personalized Medicine, Journal Year: 2022, Volume and Issue: 12(9), P. 1515 - 1515

Published: Sept. 15, 2022

Alzheimer's disease (AD) is a neurodegenerative characterized by tangle-shaped accumulation of beta-amyloid peptide fragments and Tau protein in brain neurons. The pathophysiological mechanism involves the presence Aβ-amyloid peptide, protein, oxidative stress, an exacerbated neuro-inflammatory response. This review aims to offer updated compendium most recent promising advances AD treatment through administration phytochemicals. literature survey was carried out electronic search following specialized databases PubMed/Medline, Embase, TRIP database, Google Scholar, Wiley, Web Science regarding published works that included molecular mechanisms signaling pathways targeted phytochemicals various experimental models vitro vivo. results studies showed use against has gained relevance due their antioxidant, anti-neuroinflammatory, anti-amyloid, anti-hyperphosphorylation properties protein. Some bioactive compounds from plants have been shown ability prevent stop progression Alzheimer's.

Language: Английский

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Optimization of Extraction Parameters and Anti-hyperglycemic Assessment of Standardized Extract from Santalum album L. leaves

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100577 - 100577

Published: Jan. 1, 2025

Language: Английский

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Exploring the potential of Ulva Lactuca: Emerging extraction methods, bioactive compounds, and health applications – A perspective review

South African Journal of Chemical Engineering, Journal Year: 2023, Volume and Issue: 47, P. 233 - 245

Published: Dec. 1, 2023

Ulva lactuca, commonly known as sea lettuce, is a green seaweed species that has attracted significant attention due to its remarkable potential prolific source of bioactive compounds. This comprehensive review explores the various extraction techniques harnessed isolate these compounds from Lactuca while shedding light on diverse health applications encompass. Within review, considerable emphasis placed detailing plethora inherent spanning polysaccharides, phenolic compounds, fatty acids, pigments, minerals, and vitamins. Furthermore, analysis benefits constituents provided, encompassing their roles in antioxidant activity, anti-inflammatory properties, cardiovascular health, neuroprotection, skin enhancement. Addressing broader scope this given challenges currently permeate field research, including issues related sustainability, standardization processes, formulation strategies, avenues for further exploration. examination culminates realization promising versatile reservoir ingredients, potentially revolutionising industries such food, pharmaceuticals, cosmetics. Consequently, future promises exciting prospects continued exploration exploitation Lactuca's wealth

Language: Английский

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Natural essential oils as a new therapeutic tool in colorectal cancer

Cancer Cell International, Journal Year: 2022, Volume and Issue: 22(1)

Published: Dec. 13, 2022

Colorectal cancer (CRC) is the third most revalent type of in world and second common cause death (about 1 million per year). Historically, natural compounds their structural analogues have contributed to development new drugs useful treatment various diseases, including cancer. Essential oils are odorous products made up a complex mixture low molecular weight with recognized biological pharmacological properties investigated also for prevention The aim this paper highlight possible role essential CRC, composition preclinical studies involving them. It has been reviewed determine experimental models used anticancer potential mechanisms action CRC. Searches were performed following databases PubMed/Medline, Web science, TRIP database, Scopus, Google Scholar using appropriate MeSH terms. results analyzed showed that EOs exhibited wide range bioactive effects like cytotoxicity, antiproliferative, antimetastatic on cells through action. This updated review provides better quality scientific evidence efficacy as chemotherapeutic/chemopreventive agents Future translational clinical needed establish effective dose humans well suitable route administration maximum bioavailability efficacy. Given positive obtained from studies, can be considered efficient complementary therapies chemotherapy

Language: Английский

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A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeonia emodi Wall. ex Royle: current landscape and future perspectives

Chinese Medicine, Journal Year: 2023, Volume and Issue: 18(1)

Published: March 2, 2023

Abstract Paeonia emodi Wall. ex Royle is commonly known as Himalayan paeony has great importance a food and medicine. The practice of very ancient it conventionally used for wide range illnesses in the folk system medicine because its beneficial phytochemical profile. main purpose current review was synthesis recent data on botany, ethnopharmacology, phytochemistry potential pharmacological mechanisms action Royle, thus offering new prospects development adjuvant natural therapies. Using scientific databases such PubMed/MedLine, Scopus, Web Science, ScienceDirect, Google Scholar, Springer, Wiley, comprehensive literature search performed Royle. For searching, we next MeSH terms: “Biological Product/isolation purification”, Products/pharmacology”, “Drug Discovery/methods”, “Ethnopharmacology, Medicine”, “Traditional/methods”, “Paeonia/chemistry”, “Plant Extracts/pharmacology”, “Phytochemicals/chemistry”, “Phytochemicals/pharmacology”, “Plants, Medicinal”. results most studies were analyzed important summarized tables figures. Phytochemical research led to isolation triterpenes, monoterpenes, phenolic acids, fatty organic compounds, steroids, free radicals some other classes primary metabolites. In addition, diverse activities like antibacterial, antifungal, anticoagulant, airway relaxant lipoxygenase beta-glucuronidase inhibiting activity, radical scavenging phytotoxic insecticidal have been reported Different bioactive compounds proven their therapeutic modern biomedical cure numerous gastrointestinal nervous disorders. future, further vitro vivo are required identify action, pharmacokinetics studies, pharmaceutical formulations target transport possible interaction with allopathic drugs. Also, regarding quality evaluation, toxicity safety humans needed.

Language: Английский

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Natural sources and pharmacological properties of santalenes and santalols

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 214, P. 118567 - 118567

Published: April 18, 2024

Language: Английский

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Phytosynthesis of silver nanoparticles using aqueous sandalwood (Santalum album L.) leaf extract: Divergent effects of SW-AgNPs on proliferating plant and cancer cells

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(4), P. e0300115 - e0300115

Published: April 25, 2024

The biogenic approach for the synthesis of metal nanoparticles provides an efficient eco-friendly alternative to chemical synthesis. This study presents a novel route biosynthesis silver using aqueous sandalwood (SW) leaf extract as source reducing and capping agents under mild, room temperature conditions. bioreduction Ag + o (SW-AgNPs) was accompanied by appearance brown color, with surface plasmon resonance peak at 340-360 nm. SEM, TEM AFM imaging confirm SW-AgNP’s spherical shape size range 10-32 DLS indicates hydrodynamic 49.53 nm predominant negative Zeta potential, which can contribute stability nanoparticles. FTIR analysis involvement derived polyphenols, proteins lipids in reduction SW-AgNPs. XRD determines face-centered-cubic crystalline structure SW-AgNPs, is key factor affecting biological functions cell culture methodologies evaluate effects SW-AgNPs on proliferating cells originating from plants human cancer. Exposure groundnut calli resulted enhanced proliferation leading over 70% higher biomass control, defense enzyme activities, secretion metabolites implicated biotic stress resistance (Crotonyl isothiocyanate, Butyrolactone, 2-Hydroxy-gamma-butyrolactone, Maltol) plant (dl-Threitol). MTT NRU were performed determine cytotoxicity cervical cancer cells. specifically inhibited lines SiHa (IC 50 –2.65 ppm) CaSki –9.49 ppm), indicating potential use treatment. opposing effect (enhanced proliferation) (inhibition) are both beneficial point safe application culture, agriculture

Language: Английский

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Microencapsulation of Sandalwood Essential Oil with Melamine Formaldehyde and β‐Cyclodextrin: Analysis of Study on Aroma Profile Components and Antibacterial Properties

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(16)

Published: April 1, 2025

Abstract To maintain the biological activities of sandalwood essential oil (SEO), antibacterial microcapsules were prepared through encapsulation SEO with melamine formaldehyde (MF) resin and β‐cyclodextrin (β‐CD). The micromorphology, chemical structure, thermal stability MF β‐CD characterized scanning electron microscopy, Fourier‐transform infrared spectroscopy, thermogravimetric analysis. results compared to highlight differences between microcapsules. Additionally, changes in aroma components during microencapsulation process analyzed. volatile organic compounds (VOCs) their relative contents retained throughout examined. VOCs both identified via headspace‐solid phase microextraction combined gas chromatography‐mass spectrometry. revealed that β‐santalol α‐santalol primary SEO. Even after microencapsulation, successfully its characteristic VOCs. properties evaluated using plate coating counting method. These confirmed microencapsulated maintained significant activity against Escherichia coli Staphylococcus aureus . This study provides valuable theoretical insights support future research on release behavior

Language: Английский

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Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications

Chinese Medicine, Journal Year: 2022, Volume and Issue: 17(1)

Published: Sept. 29, 2022

Abstract Background A biennial or perennial plant of the Apiaceae family, Eryngium caeruleum M. Bieb. is traditionally used in medicine as an antitoxic, diuretic, digestive, anti-inflammatory and analgesic drug. This widely distributed temperate regions around world. Young leaves are cooking aromatic cooked vegetables various local products Iran. Purpose The current review aimed to highlight complete updated information about species, regarding botanical, ethnopharmacological, phytochemical data, pharmacological mechanisms well some nutritional properties. All this scientific evidence supports use species complementary medicine, thus opening new therapeutic perspectives for treatment diseases. Methods provided collected from several databases such PubMed/Medline, ScienceDirect, Mendeley, Scopus, Web Science Google Scholar. Ethnopharmacology books professional websites were also researched. Results composition aerial parts roots E. represented by components essential oil (EO), phenolic compounds, saponins, protein, amino acids, fiber, carbohydrates, mineral elements. antioxidant, antimicrobial, antidiabetic, antihypoxic, properties have been confirmed experiments with extracts using vitro vivo methods. syrup relieved dysmenorrhea effectively Ibuprofen blinded, randomized, placebo-controlled clinical study. Conclusion Current experimental studies has shown that different bioactive compounds present multiple beneficial effects on human health, being potentially active many Thus, traditional uses supported based evidence. In future, translational necessary establish effective doses humans.

Language: Английский

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