Can we predict sleep health based on brain features? A large-scale machine learning study DOI Creative Commons
Federico Raimondo, Hanwen Bi, Vera Komeyer

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 13, 2024

Abstract Objectives Normal sleep is crucial for brain health. Recent studies have reported robust associations between disturbance and various structural functional traits. However, the complex interplay health macro-scale organization remains inconclusive. In this study, we aimed to uncover links imaging features diverse health-related characteristics by means of Machine Learning (ML). Methods We used 28,088 participants from UK Biobank calculate 4677 neuroimaging markers. Then, employed them predict self-reported insomnia symptoms, duration, easiness getting up in morning, chronotype, daily nap, daytime sleepiness, snoring. built seven different linear nonlinear ML models each characteristic assess their predictability. Results performed an extensive analysis that involved more than 100,000 hours computing. observed relatively low performance predicting all (e.g., balanced accuracy ranging 0.50-0.59). Across models, best achieved was 0.59, using a Linear SVM morning. Conclusions The capability multimodal markers characteristics, even under optimization large population sample suggests relationship organization.

Language: Английский

Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study DOI Creative Commons
Yanwei You, Yuquan Chen, Ruidong Liu

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: March 15, 2024

Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting healthy aging. This study aims to (i) identify the sleep duration trend US adults; (ii) investigate relationship between and phenotypic age; (iii) explore role of exercise this relationship. Phenotypic age as novel index was calculated according biomarkers collected from adults based on National Health Nutrition Examination Survey (NHANES). information self-reported by participants discerned through individual interviews. The principal analytical method employed weighted multivariable linear regression modeling, which accommodated for complex multi-stage sampling design. potential non-linear explored using restricted cubic spline (RCS) model. Furthermore, subgroup analyses evaluated effects sociodemographic lifestyle factors primary outcomes. A total 13,569 were finally included in, thereby resulting population 78,880,615. An examination temporal trends revealed declining proportion individuals with insufficient markedly deficient time since 2015-2016 cycle. Taken normal group reference, extreme short [β (95% CI) 0.582 (0.018, 1.146), p = 0.044] long 0.694 (0.186, 1.203), 0.010] both positively associated fully adjusted According dose-response age, benefit regular activity, whereas more tended have higher age. There an inverted U-shaped durations represents important step forward our understanding By shedding light topic providing practical recommendations habits, researchers help live longer, healthier, fulfilling lives.

Language: Английский

Citations

53
Sleep duration, chronotype, health and lifestyle factors affect cognition: a UK Biobank cross-sectional study DOI Creative Commons

Raha West,

Ryan Wong, Ji‐Eun Park

et al.

BMJ Public Health, Journal Year: 2024, Volume and Issue: 2(1), P. e001000 - e001000

Published: May 1, 2024

To explore the nuanced relationship between sleep patterns, chronotype, quality and influence of health lifestyle factors on cognitive performance. This cross-sectional analysis used ordinary least squares regression within UK Biobank database, assessing 26 820 participants aged 53-86 years, categorised into two cohorts: Cohort 1 (10 067 participants, 56% female; completed all four tests Fluid Intelligence/reasoning, Pairs Matching, Reaction Time Prospective Memory) 2 (16 753 only assessments Matching Time). Participant's self-reported duration, chronotype quality. Cognitive function was assessed through standardised computerised tests. The adjusted for demographic comorbidity covariates. performance scores were evaluated against parameters including sex, age, vascular cardiac conditions, diabetes, alcohol intake, smoking habits body mass index. highlighted a positive association normal duration (7-9 hours) in (β=0.0567, 95% CI 0.0284 to 0.0851), while extended negatively impacted across both cohorts (Cohort 1: β=-0.188, -0.2938 -0.0822; 2: β=-0.2619, -0.3755 -0.1482). Chronotype distinctions, particularly intermediate evening types, linked superior function. Gender, angina, high blood pressure, intake emerged as significant influencers. study delineates multifaceted variables, determining outcomes. These findings highlight vital role health.

Language: Английский

Citations

6
Threshold effects of sleep duration and cognitive function in older adults with BMI ≥ 25 kg/m2 DOI Creative Commons
Kunyu Qiu, Yilei Liu, Chengwei Hu

et al.

Frontiers in Aging Neuroscience, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 7, 2025

It has been demonstrated that older adults' cognitive capacities can be improved with sleep duration. However, the relationship between overweight, obesity, and decline remains a subject of debate. The impact duration on performance in seniors body mass index (BMI) ≥ 25 kg/m2 is largely unknown. This makes it an intriguing to explore further. study used data from National Health Nutrition Examination Survey (NHANES) (2011-2014) 2,243 participants. Weighted multivariate linear regression smooth curve fitting were employed investigate non-linear relationships. A two-part model was determine threshold effects. Additionally, subgroup analysis interaction tests conducted. Results showed negative association found scores fully adjusted Consortium Establish Registry for Alzheimer's Disease (CERAD) test, Animal Fluency test (AFT), Digit Symbol Substitution (DSST). two-piecewise then applied effect performance. When less than 5 6 h per day, positively correlated CERAD [ß (95% CI): 2.11 (1.17, 3.05), p < 0.0001], AFT [β 0.25 (-0.17, 0.67), = 0.2376], DSST 0.49 (-0.57, 1.56), 0.3654]. there where reached three inflection points. In overweight obese adults, clear inverted U-shaped function, consistent results across different subgroups. Sleep durations around 5-6 may help prevent adults BMI kg/m2.

Language: Английский

Citations

0
Sleep Patterns and Human Brain Health DOI Creative Commons
Anders M. Fjell, Kristine B. Walhovd

The Neuroscientist, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

It is a widely held opinion that sleep important for human brain health. Here we examine the evidence this view, focusing on normal variations in patterns. We discuss functions of and highlight paradoxical implications theories seeing as an adaptive capacity versus theory benefits clearance metabolic waste from brain. also evaluate proposition plays active role consolidation memories. Finally, review research possible effects chronic deprivation find causal health surprisingly weak relative to amount attention science society. While there are well-established associations between parameters aspects health, results generally not consistent across studies measures, it clear what extent alterations patterns represent symptoms or causes. Especially, long (>8 hours) general beneficial long-term humans seems lack empirical support. suggest directions future establish solid foundation knowledge about based longitudinal with frequent sampling, individual differences, more ecologically valid intervention studies.

Language: Английский

Citations

0
Association between sleep duration and disability in activities of daily living among Chinese older adults: a nationwide observational study DOI Creative Commons
Dan Cai,

Yanxin Zeng,

Min Chen

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: May 21, 2025

Background This study aims to explore the relationship between sleep duration and Activity of Daily Living (ADL) disability among older adults in China. ADL severely impacts quality life is associated with various physical mental health issues. With aging population China, burden increasing. Methods Data were sourced from 2018 national follow-up Chinese Longitudinal Healthy Longevity Survey (CLHLS), including 9,572 participants aged 65 above. Sleep was assessed via self-reported questionnaire categorized into short (&lt;7 h), medium (7–8 long (≥9 h). evaluated through Basic Activities (BADL) Instrumental (IADL). Logistic regression models used analyze disability, subgroup analyses conducted differences by gender activity. Results The found a significant non-linear disability. Compared 7–8 h, those over 9 h had significantly higher risk BADL IADL (OR = 1.36, OR 1.35). Subgroup indicated that this existed different genders, age, activity levels. Conclusion For maintaining may be an effective strategy for preventing Both excessively are increased population.

Language: Английский

Citations

0
Shorter self-reported sleep duration is associated with worse virtual spatial navigation performance in men DOI Creative Commons
Emre Yavuz, Christoffer J. Gahnstrom, Sarah Goodroe

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 19, 2024

Sleep has been shown to impact navigation ability. However, it remains unclear how different sleep-related variables may be independently associated with spatial performance, and as whether gender play a role in these associations. We used mobile video game app, Sea Hero Quest (SHQ), measure wayfinding ability US-based participants. Wayfinding performance on SHQ correlate real-world wayfinding. Participants were asked report their sleep duration, quality, daytime sleepiness nap frequency duration typical night (n = 766, 335 men, 431 women, mean age 26.5 years, range 18-59 years). A multiple linear regression was identify which self-reported performance. Shorter durations significantly worse men only. Other showed non-significant trends of association When removing non-typical sleepers (< 6 or > 9 h night), the significant between no longer present. These findings from U.S.-based participants suggest that an important contributor successful men.

Language: Английский

Citations

2
The effects of sleep deprivation on risky decision making DOI

Wei Xue,

Junshu Ma,

Sijia Liu

et al.

Psychonomic Bulletin & Review, Journal Year: 2024, Volume and Issue: unknown

Published: July 30, 2024

Language: Английский

Citations

2
Shorter self-reported sleep duration in men is associated with worse virtual spatial navigation performance DOI Open Access
Emre Yavuz, Alpár S. Lázár, Christoffer J. Gahnstrom

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 9, 2023

Abstract Sleep has been shown to impact navigation ability. However, it remains unclear how different sleep-related variables may be independently associated with spatial performance, and as whether gender play a role in these associations. We used mobile video game app, Sea Hero Quest (SHQ), measure wayfinding ability US-based participants. Wayfinding performance on SHQ correlate real-world wayfinding. Participants were asked report their sleep duration, quality, daytime sleepiness nap frequency duration typical night (n = 737, 409 men, 328 women, mean age 27.1 years, range 18-59 years). A multivariate linear regression was identify which self-reported performance. For longer durations better no such association found. While other showed trends of none significantly our model. These findings from younger U.S.-based participants suggest that an important contributor successful men.

Language: Английский

Citations

4
Association between residential greenness and incident delirium: A prospective cohort study in the UK Biobank DOI
Qida He, Mengtong Sun, Yu Wang

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 937, P. 173341 - 173341

Published: May 24, 2024

Language: Английский

Citations

1
Sex differences in dorsolateral prefrontal cortical and superior colliculus activities support the impact of alcohol use severity and sleep deficiency on two-back memory DOI Open Access
Guangfei Li,

Cao Yingjie,

Chunlan Yang

et al.

Quantitative Imaging in Medicine and Surgery, Journal Year: 2024, Volume and Issue: 14(7), P. 4972 - 4986

Published: June 29, 2024

Working memory refers to a process of temporary storage and manipulation information support planning, decision-making, action. Frequently comorbid alcohol misuse sleep deficiency have both been associated with working deficits. However, how interact impact remains unclear. In this study, we aim investigate the neural processes inter-relating misuse, memory.

Language: Английский

Citations

1