Metabolic Characteristics of Hashimoto’s Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management—An Overview

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(12), P. 6580 - 6580

Published: June 13, 2022

Hashimoto's thyroiditis (HT) is the most common autoimmune disease and leading cause of hypothyroidism, in which damage to thyroid gland occurs due infiltration lymphocytes. It characterized by increased levels antibodies against peroxidase thyroglobulin. In this review, we present metabolic profile, effectiveness micronutrient supplementation impact dietary management patients with HT. For current literature databases PubMed, Cochrane, Medline Embase were reviewed from last ten years until March 2022. This article provides a comprehensive overview recent randomized controlled trials, meta-analyses, clinical trials. Many HT, even euthyroid state, have excess body weight, disorders, reduced quality life. Due frequent concomitant nutritional deficiencies, role vitamin D, iodine, selenium, magnesium, iron B12 currently debated. Several studies underlined benefits D selenium supplementation. There still no specific diet recommended for but protective effect an anti-inflammatory rich vitamins minerals low animal foods has been suggested. insufficient evidence support gluten-free all HT patients. Pharmacotherapy, along appropriate nutrition supplementation, are important elements medical care The abovementioned factors may decrease autoantibody levels, improve function, slow down inflammatory process, maintain proper relieve symptoms, prevent deficiencies development disorders

Language: Английский

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The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis

Annals of Agricultural and Environmental Medicine, Journal Year: 2019, Volume and Issue: 27(2), P. 184 - 193

Published: Oct. 2, 2019

1. Krysiak R, Szkróbka W, Okopień B. The Effect of Gluten-Free Diet on Thyroid Autoimmunity in Drug-Naïve Women with Hashimoto's Thyroiditis: A Pilot Study. Exp Clin Endocrinol Diabetes. 2018 Jul 30. https://doi.org/10.1055/a-0653.... CrossRef Google Scholar

Language: Английский

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Subclinical Hypothyroidism in Patients with Obesity and Metabolic Syndrome: A Narrative Review

Nutrients, Journal Year: 2023, Volume and Issue: 16(1), P. 87 - 87

Published: Dec. 27, 2023

The literature on the connection between obesity, metabolic syndrome, and subclinical hypothyroidism is critically analyzed in this narrative review. These conditions are frequently observed among adult populations various studies meta-analyses have assessed their association. prevalence of obese individuals higher than non-obese subjects trend more pronounced unhealthy obesity phenotypes. However, diagnosis treatment can be difficult patients. Exaggerated body fat linked to thyroid hypoechogenicity as evident through ultrasonography euthyroid people greater TSH, FT3, FT3/FT4 ratios a condition. Moreover, reduced expression TSH receptor altered function deiodinases has been found adipose tissue Current data do not support necessity pharmacological correction isolated hyperthyrotropinemia patients because with hormone does significantly improve weight loss increase serum reversible after hypocaloric diet or bariatric surgery. On other hand, elevated leptin levels. Inflammation raise risk Hashimoto thyroiditis, which increases likelihood that will experience overt hypothyroidism. Both syndrome associated atherosclerosis, liver kidney disease. Hence, association these two illnesses may potentiate adverse effects noted each them. Subclinical should identified treated appropriate doses L-thyroxine according lean mass weight. Randomized controlled trials necessary verify whether deficiency could counteract expected risks.

Language: Английский

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Dietary Patterns and Hypothyroidism in U.S. Adult Population

Nutrients, Journal Year: 2024, Volume and Issue: 16(3), P. 382 - 382

Published: Jan. 28, 2024

The thyroid gland produces hormones that are essential for various body functions. Hypothyroidism is defined as insufficient hormone production. Several studies have found associations between specific micronutrients and overall function; however, the amount of evidence regarding relationship dietary patterns hypothyroidism among U.S. population limited. Data from three cycles National Health Nutrition Examination Surveys (NHANES), 2007-2008, 2009-2010, 2011-2012, were used (n = 8317). Subjects with serum stimulating >4.5 mIU/L or on levothyroxine considered to hypothyroidism. Age, sex, race/ethnicity, mass index, several lifestyle factors covariates. Three extracted using factor analysis. These labeled fat-processed grains-sugars-meats (FPSM), oils-nuts-potatoes-low-fat meats (ONPL), fruits-whole grains-vegetables-dairy (FWVD) patterns. In a weighted multiple logistic regression, FPSM ONPL inversely associated (OR, 0.75; 95% CI, 0.57-1; p 0.049 OR, 0.81; 0.67-0.97; 0.025, respectively). However, FWVD demonstrated no association (p 0.63). conclusion, but not in adults. Nutrient deficiencies their interactions may be linked

Language: Английский

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Comprehensive Analysis of Novel Synergistic Antioxidant Formulations: Insights into Pharmacotechnical, Physical, Chemical, and Antioxidant Properties

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 690 - 690

Published: May 27, 2024

(1) Background: Oxidative stress plays a pivotal role in the pathogenesis of various diseases, including neurodegenerative disorders, cardiovascular cancer, and diabetes, highlighting pressing need for effective antioxidant interventions. (2) Methods: In this study, we aimed to develop characterise two novel formulations, F3 F4, as therapeutic interventions oxidative stress-related conditions. (3) Results: The physicochemical characterisation, preformulation analysis, formulation, preparation filling powders capsules, capsule content evaluation, activity assessment formulations were assessed. These comprise combination well-established antioxidants like quercetin, biotin, coenzyme Q10, resveratrol. Through comprehensive testing, formulations' efficacy, stability, potential synergistic interactions evaluated. (4) Conclusions: findings underscore promising these disorders highlight significance mitigating their progression.

Language: Английский

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Assessment of Vitamin Concentrations in Patients with Hashimoto’s Thyroiditis and Their Relationships with Thyroid Function, Biochemical Status, and Anthropometric Parameters—A Preliminary Study

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1694 - 1694

Published: May 29, 2024

Hashimoto’s thyroiditis (HT) is the leading cause of hypothyroidism, affecting mainly female population. Many patients with HT have metabolic disorders and nutritional deficiencies. The aim this study was to evaluate vitamin D, A, E, B2, B6 concentrations, thyroid function, profile, anthropometric parameters thyroiditis. In 81 (study group), A B2 concentrations were significantly lower than in 34 healthy women (control group). No differences noted between groups. Moreover, had similar parameters, lipid profiles, glucose insulin compared controls. This showed some relationships or biochemical profiles patients. Among others, group, concentration D positively correlated level HDL negatively BMI, total fat mass, level, which influence cardiovascular risk. results indicate that should be routinely tested for prevent Further studies are also needed on role vitamins development progression presence complications

Language: Английский

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The association between dietary inflammatory index and dietary total antioxidant capacity and Hashimoto’s thyroiditis: a case-control study

BMC Endocrine Disorders, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 5, 2024

Language: Английский

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Nutrition, intestinal microbiota, and thyroid autoimmune pathology

Russian Journal of Preventive Medicine, Journal Year: 2025, Volume and Issue: 28(1), P. 102 - 102

Published: Jan. 1, 2025

Language: Английский

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The relationship between immigrant status, cultural/racial background, and hypothyroidism among middle-aged and older Canadians: An analysis of Canadian Longitudinal Study on Aging data

Archives of Gerontology and Geriatrics Plus, Journal Year: 2025, Volume and Issue: unknown, P. 100129 - 100129

Published: Feb. 1, 2025

Language: Английский

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Physical Activity, Nutritional Behaviours and Depressive Symptoms in Women with Hashimoto’s Disease

Healthcare, Journal Year: 2025, Volume and Issue: 13(6), P. 620 - 620

Published: March 13, 2025

An important element of supporting pharmacotherapy in hypothyroidism is a pro-health lifestyle, with rational nutrition and recreational physical activity playing roles. Objectives: The aim this study was to analyse selected behavioural determinants depressive states women Hashimoto’s disease. Methods: This conducted among 219 aged 20–50 using the following: (i) author’s questionnaire nutritional behaviours for people (QNB); (ii) International Physical Activity Questionnaire (IPAQ); (iii) Beck Depression Scale (SDB). Statistical analysis performed Statistica 13.1 JASP programmes, Spearman’s R correlation analysis, Kruskal–Wallis variance regression at significance level α = 0.05. Results: It found that symptoms were weakly negatively associated moderate activity. At same time, low levels demonstrated higher vigorous than high depression. decreased implementation some dietary recommendations, including consumption products rich iodine, iron, zinc, selenium, vitamin D, A polyunsaturated omega-3 fatty acids. occurrence constipation, requiring high-fibre diet, positively Regression showed model consisting all QNB items explained 18% depression symptoms. Conclusions: In summary, disease, choices lower intensity Promoting healthy lifestyle may help improve mental state patients

Language: Английский

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