Association of screen exposure/sedentary behavior and precocious puberty/early puberty DOI Creative Commons
Xinyu Wu, Ling-Mei Wang, Peng Xue

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: Sept. 23, 2024

Background In recent years, with the development of society, children's daily exposure to screen time has gradually increased. Screen and sedentary behavior have brought a host harms lives. The aim this study was explore effects on precocious puberty early development. Methods This is cross-sectional in school-based population. A total 3,560 children were recruited from Qufu City, Shandong province using multistage stratified cluster random sampling. All subjects had physical examination by professional pediatricians October 2019, investigated health questionnaires. Precocious defined as secondary sexual signs boys before 9 years or girls 8 years. calculated average weekdays weekend days, days. After adjusting for potential confounders, logistic regression used examine association between puberty. Results Sedentary risk factor (OR = 1.428, 95% CI 1.087–1.876) without adjustment. No significant found both boys. Conclusions Excessive associated an increased puberty, especially girls, while there no addition, further longitudinal investigations are needed determine causal relationship exposure,

Language: Английский

Effects of Blue Light on Puberty and Ovary in Female Rats DOI Creative Commons
Aylin Kılınç Uğurlu, Aysun Bıdecı, Mürşide Ayşe Demırel

et al.

Journal of Clinical Research in Pediatric Endocrinology, Journal Year: 2023, Volume and Issue: 15(4), P. 365 - 374

Published: May 22, 2023

What is already known on this topic?Blue light a source in our lives.However, recent years, exposure to blue has increased with the use of mobile devices and tablets.The severity impacts increases as eye-screen distance decreases.The these children increased, melatonin suppression cause disruption circadian rhythm, appetite, obesity.However, its effects puberty are unknown.What does study add?Early was observed due prepubertal period.When apoptosis polycystic ovary appearance were detected ovaries.

Language: Английский

Citations

5

Is blue light exposure a cause of precocious puberty in male rats? DOI Creative Commons
Aylin Kılınç Uğurlu, Aysun Bıdecı,

Ayşe Mürşide Demirel

et al.

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: June 20, 2023

Purpose Our study aimed to examine the effects of blue light exposure on prepubertal male rats’ puberty and testis tissue. Methods Eighteen 21-day-old Sprague Dawley rats were divided into three groups consisting six in each group: Control Group (CG), Blue Light-6 hours (BL-6), Light-12 (BL-12). CG maintained with 12/12-hour light-dark cycles. The BL-6 BL-12 exposed (450-470nm/irradiance level 0.03uW/cm2) for 6 12 hours, respectively. Rats until first signs puberty. ELISA method was used analyze serum levels FSH, LH, testosterone, DHEA-S, leptin, ghrelin, melatonin, glutathione, glutathione peroxidase, malondialdehyde. Testes dissected histomorphological examination. Results medians pubertal entry days CG, BL-6, 38 th , 30 28 days, (p:0.001) testosterone concentrations all similar. FSH concentration increased as LH (r: 0.82 p: 0.001). DHEAS decreased, respectively -0.561, 0.01) (r:-0.55 p:0.01). Testicular lengths weights BL smaller compared (p: 0.03),(p: 0.04). GPx higher than (p:0.021, p:0.024). Testis tissue compatible period groups. As time increased, spermatogenesis suppressed, capillary dilatation edema increased. Conclusion is show process. And we showed that duration lead precocious rats. suppressed spermatogenesis, marked vasodilatation interstitial area testis, disrupted integrity basement membrane. These findings intensified increasing time.

Language: Английский

Citations

5

Clinical Management and Therapy of Precocious Puberty in the Sapienza University Pediatrics Hospital of Rome, Italy DOI Creative Commons
Ginevra Micangeli, Roberto Paparella, Francesca Tarani

et al.

Children, Journal Year: 2023, Volume and Issue: 10(10), P. 1672 - 1672

Published: Oct. 10, 2023

Puberty identifies the transition from childhood to adulthood. Precocious puberty is onset of signs pubertal development before age eight in girls and nine boys, it has an incidence 1/5000–1/10,000 with F:M ratio ranging 3:1 20:1. can be divided into central, also known as gonadotropin-dependent precocious or true puberty, peripheral, recognized gonadotropin-independent pseudopuberty. Thus, main aim this narrative report describe standard clinical management therapy according experience expertise pediatricians pediatric endocrinologists at Policlinico Umberto I, Sapienza University Rome, Italy. In suspicion early sexual maturation, important collect information regarding onset, speed maturation secondary features, exposure exogenous sex steroids presence neurological symptoms. The objective examination, addition evaluation characteristics, must include auxological parameters. Initial laboratory investigations should serum gonadotropin levels (LH FSH) steroids. Brain MRI performed indicated by 2009 Consensus Statement all boys regardless chronological 6 years age. gold treatment central represented GnRH analogs, whereas, far peripheral forms are concerned, triggering cause identified treated. At moment there no reliable data establishing criteria for discontinuation analog therapy. However, numerous pieces evidence suggest that suspended physiological which occurs.

Language: Английский

Citations

4

Early Puberty Trend during the COVID-19 Pandemic in Singapore: A Retrospective Review in a Single Tertiary Centre DOI Creative Commons
Annie Leong, Rashida Farhad Vasanwala

Journal of the ASEAN Federation of Endocrine Societies, Journal Year: 2024, Volume and Issue: 39(1), P. 6 - 11

Published: May 25, 2024

We aimed to study the trend of referrals for precocious puberty during COVID-19 pandemic compared pre-COVID years, explore differences in demographic and clinical features, evaluate contributing factors.

Language: Английский

Citations

1

Association of screen exposure/sedentary behavior and precocious puberty/early puberty DOI Creative Commons
Xinyu Wu, Ling-Mei Wang, Peng Xue

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: Sept. 23, 2024

Background In recent years, with the development of society, children's daily exposure to screen time has gradually increased. Screen and sedentary behavior have brought a host harms lives. The aim this study was explore effects on precocious puberty early development. Methods This is cross-sectional in school-based population. A total 3,560 children were recruited from Qufu City, Shandong province using multistage stratified cluster random sampling. All subjects had physical examination by professional pediatricians October 2019, investigated health questionnaires. Precocious defined as secondary sexual signs boys before 9 years or girls 8 years. calculated average weekdays weekend days, days. After adjusting for potential confounders, logistic regression used examine association between puberty. Results Sedentary risk factor (OR = 1.428, 95% CI 1.087–1.876) without adjustment. No significant found both boys. Conclusions Excessive associated an increased puberty, especially girls, while there no addition, further longitudinal investigations are needed determine causal relationship exposure,

Language: Английский

Citations

1