Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings
A. S. Alberts,
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Dana-Ionela Tudorache,
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Adelina-Gabriela Niculescu
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et al.
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent
advancements
in
wound
dressing
materials
have
significantly
improved
acute
and
chronic
management
by
addressing
challenges
such
as
infection
control,
moisture
balance,
enhanced
healing.
Important
progress
has
been
made,
especially
with
hydrogels,
foams,
antimicrobial
for
creating
optimized
dressings.
Hydrogels
are
known
maintaining
optimal
levels,
while
foam
dressings
excellent
exudate
absorbents.
Meanwhile,
incorporates
various
agents
to
reduce
risks.
These
options
healing
time
focusing
on
customized
patient
needs.
Therefore,
this
review
highlights
the
newest
research
prototypes
applications,
emphasizing
their
particular
benefits
clinical
importance.
Innovations
stimuli-responsive
hydrogels
hybrid
bioengineered
composites
discussed
relation
properties,
including
responsiveness
pH,
temperature,
glucose,
or
enzymes
drug
delivery
precision.
Moreover,
ongoing
trials
included,
demonstrating
potential
of
emerging
solutions
be
soon
translated
from
laboratory
settings.
By
discussing
interdisciplinary
approaches
that
integrate
advanced
materials,
nanotechnology,
biological
insights,
work
provides
a
contemporary
framework
patient-centric,
efficient
care
strategies.
Language: Английский
Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats
Jing Li,
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Linai Li,
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Yue Yu
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et al.
Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: Jan. 29, 2025
Skin
wound
healing
is
a
complex
physiological
process
that
involves
many
different
cell
types
and
signaling
molecules.
In
traditional
Chinese
medicine,
A.
membranaceus
Panax
notoginseng
are
commonly
used
together
for
the
treatment
of
injury
their
significant
efficacy.
The
application
new
materials
may
make
-P.
(AP)
play
better
curative
effect.
this
study,
we
fabricated
Carboxymethyl
chitosan-Sodium
alginate
hydrogel
loaded
with
extract
Astragalus
-
P.
(APCS),
which
showed
favorable
stability,
biocompatibility,
ability
to
rapidly
release
drugs.
Cell
culture
experiments
demonstrated
APCS
dramatically
increased
fibroblast
proliferation,
migration,
differentiation
into
myofibroblast.
vivo
on
SD
rats
hydrogels
significantly
accelerated
skin
healing,
reduced
inflammatory
response,
enhanced
formation
blood
vessels,
granulation
tissues,
collagen
fibers,
promoted
re-epithelialization
at
site.
Increased
expression
catalase,
VEGF,
PGP9.5
tissue
indicated
inhibited
oxidative
stress
vascular
neuronal
regeneration.
summary,
displayed
great
potential
as
dressing
achieving
satisfactory
full-thickness
wounds.
Language: Английский
Exploring the therapeutic potential of ligand-decorated nanostructured lipid carriers for targeted solid tumor therapy
Zrien Naz,
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Mohammad Fareed,
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Abdur Rahman Hamidullah Chaudhary
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et al.
International Journal of Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
678, P. 125687 - 125687
Published: May 9, 2025
Language: Английский
Mechanistic Wound Healing of Ficus trijuja Leaf Extract and Its Lipid Nanocapsule Supported by Metabolomic Profiling and In Vivo Studies
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(3), P. 928 - 928
Published: Jan. 23, 2025
This
study
explores
the
metabolic
profile
and
wound-healing
capabilities
of
Ficus
trijuja,
a
species
within
Moraceae
family,
for
first
time.
plants
contain
variety
secondary
metabolites
such
as
flavonoids,
triterpenoids,
alkaloids,
known
their
antioxidant,
anti-inflammatory,
cytotoxic
properties.
Previous
studies
demonstrated
effectiveness
extracts
in
wound
healing,
with
evidence
improved
contraction,
strength,
faster
epithelization.
shows
impact
F.
trijuja
extract
gel
base
well
when
delivered
through
lipid
nanocapsules
(LNCs)
formula,
on
all
phases
rats,
by
determining
expression
levels
key
markers.
The
results
indicated
that
treatment
accelerated
particularly
applied
nanocapsulation,
which
comparable
efficacy
to
standard
treatments
like
MEBO®
approximately
2.62%
improvement
healing
compared
itself.
Understanding
these
molecular
markers
offers
insights
developing
targeted
therapies
optimize
prevent
complication
development.
To
unravel
phytochemical
composition
extract,
LC-HRESIMS
analysis
was
implemented,
revealed
24
belonging
different
classes
terpenoids,
megastigmane.
In
conclusion,
both
its
nanoformulation
have
proven
vivo
can
be
further
investigated
potential
clinical
use.
Language: Английский
Polymer‐ and Lipid‐Based Nanostructures Serving Wound Healing Applications: A Review
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 14, 2024
Abstract
Management
of
hard‐to‐heal
wounds
often
requires
specialized
care
that
surpasses
the
capabilities
conventional
treatments.
Even
most
advanced
commercial
products
lack
functionality
to
meet
needs
wounds,
especially
those
complicated
by
active
infection,
extreme
bleeding,
and
chronic
inflammation.
The
review
explores
how
supramolecular
nanovesicles
nanoparticles—such
as
dendrimers,
micelles,
polymersomes,
lipid‐based
nanocarriers—can
be
key
introducing
wound
healing
monitoring
properties
address
complex
wounds.
Their
potential
enable
functions
essential
for
next‐generation
products—such
hemostatic
functions,
transdermal
penetration,
macrophage
polarization,
targeted
delivery,
controlled
release
pharmaceutical
ingredients
(antibiotics,
gaseous
products,
anti‐inflammatory
drugs,
growth
factors)—is
discussed
via
an
extensive
overview
recent
reports.
These
studies
highlight
integration
systems
in
is
crucial
advancing
toward
a
new
generation
addressing
significant
gaps
current
management
practices.
Current
strategies
improvements
regarding
personalized
therapies,
promising
critically
evaluated
but
underexplored
polymer‐based
nanovesicles,
including
polymersomes
proteinosomes,
healing.
Language: Английский
Tacrolimus: Physicochemical stability challenges, analytical methods, and new formulations
Sara Sajjadi,
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Ali Shayanfar,
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Farhad Kiafar
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et al.
International Journal of Pharmaceutics X,
Journal Year:
2024,
Volume and Issue:
8, P. 100285 - 100285
Published: Sept. 15, 2024
Language: Английский
Contemporary strategies in glioblastoma therapy: Recent developments and innovations
Mariya Khan,
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Modassir Nasim,
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Mohammadamin Feizy
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et al.
Neuroscience,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 1, 2024
Language: Английский
Multifaceted Role of Nanocomposite Hydrogels in Diabetic Wound Healing: Enhanced Biomedical Applications and Detailed Molecular Mechanisms
Gege Xiong,
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Qiwei Chen,
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Qiuyu Wang
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et al.
Biomaterials Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Nanocomposite
hydrogels
offer
a
promising
approach
to
treating
diabetic
wounds.
Key
findings
include
enhanced
mechanical
properties,
antibacterial
effects,
and
the
ability
regulate
wound
microenvironment.
Language: Английский