Journal of Public Health, Journal Year: 2019, Volume and Issue: 28(5), P. 605 - 622
Published: April 5, 2019
Language: Английский
Journal of Public Health, Journal Year: 2019, Volume and Issue: 28(5), P. 605 - 622
Published: April 5, 2019
Language: Английский
Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15
Published: March 11, 2024
Background Poor sleep quality significantly impacts academic performance in university students. However, inconsistent and inconclusive results were found a study on among students several African nations. Therefore, this aimed to estimate the pooled prevalence associated factors of poor Africa. Methods The databases PubMed, Scopus, Cochrane Library, Science Direct, Journal Online, Google Scholar searched identify articles. A total 35 primary articles from 11 countries assessed included systematic review meta-analysis. Data extracted by using Microsoft Excel spreadsheet exported STATA version 14 for analysis. I 2 test was used assess statistical heterogeneity. random effect meta-analysis model employed with 95% confidence intervals. Funnel plots analysis Egger regression tests check presence publication bias. subgroup sensitivity done. Results 16,275 participants studies review. overall Africa 63.31% (95% CI: 56.91-65.71) = 97.2. shows that combined East, North, West, South 61.31 56.91-65.71), 62.23 54.07-70.39), 54.43 47.39-61.48), 69.59 50.39-88.80) respectively. Being stressed (AOR= 2.39; 1.63 3.51), second year 3.10; 2.30 4.19), use electronic device at bedtime 3.97 2.38 6.61)) having comorbid chronic illness (AOR 2.71; 1.08, 6.82) quality. Conclusion This there is high stressed, year, devices bedtime, addressing contributing implementing routine screenings are essential reduce burden Systematic Review Registration https://www.crd.york.ac.uk/prospero/ , identifier CRD42023493140.
Language: Английский
Citations
16BMC Medical Education, Journal Year: 2012, Volume and Issue: 12(1)
Published: Aug. 1, 2012
The relationship between the sleep/wake habits and academic performance of medical students is insufficiently addressed in literature. This study aimed to assess sleep duration with students. was conducted December 2009 January 2010 at College Medicine, King Saud University, included a systematic random sample healthy first (L1), second (L2) third (L3) levels. A self-administered questionnaire distributed demographics, schedule, habits, duration. Daytime sleepiness evaluated using Epworth Sleepiness Scale (ESS). School stratified as “excellent” (GPA ≥3.75/5) or “average” <3.75/5). final analysis 410 (males: 67%). One hundred fifteen (28%) had performance, 295 (72%) performance. group higher ESS score percentage who felt sleepy during class. In contrast, an earlier bedtime increased TST weekdays. Subjective feeling obtaining sufficient non-smoking were only independent predictors Decreased nocturnal time, late bedtimes weekdays weekends daytime are negatively associated
Language: Английский
Citations
183SLEEP, Journal Year: 2013, Volume and Issue: 36(5), P. 769 - 779
Published: May 1, 2013
We hypothesize that extremes of sleep duration are associated with elevated C-reactive protein (CRP), a pro-inflammatory marker for cardiovascular disease risk. Cross-sectional. Population-based research. Nationally representative sample 2007-2008 National Health and Nutrition Examination Survey participants (n = 5,587 adults). None. Associations between CRP self-reported total time (TST) were examined. Explanatory models considered contributions sex, age, race/ethnicity, body mass index (BMI), BMI squared (BMI2). Models also explored the role insomnia symptoms, apnea, active medical illness, antidiabetic/antihypertensive treatment. Differential patterns among race/ethnicity groups examined using interactions stratified analyses. Nonlinear relationships TST assessed polynomial multinomial regression (< 5, 6, 7, 8, 9, > 9 h). Linear terms significant in all complete sample, notable differences by sex ethnoracial group. Overall, adjusted sociodemographics BMI, different observed non-Hispanic white (elevated < 5 h h), black/African-American 8 Hispanic/Latino Asian/ Other (higher lower 6 h) groups. Ethnoracial demonstrated patterning sex. In American adults, was extreme durations. Sex, disorders, comorbidity influenced these associations. Differences along dimensions should be future research on related disparities influencing cardiometabolic
Language: Английский
Citations
161Current Diabetes Reports, Journal Year: 2016, Volume and Issue: 16(11)
Published: Sept. 23, 2016
Language: Английский
Citations
160Physiological Genomics, Journal Year: 2012, Volume and Issue: 44(20), P. 981 - 991
Published: Aug. 29, 2012
Sleep deprivation is a common problem of considerable health and economic impact in today's society. loss associated with deleterious effects on cognitive functions such as memory has high comorbidity many neurodegenerative neuropsychiatric disorders. Therefore, it crucial to understand the molecular basis effect sleep brain. In this study, we combined genome-wide traditional biological approaches determine cellular impacts mouse hippocampus, brain area for forms memory. Microarray analysis examining 5 h gene expression hippocampus found 533 genes altered expression. Bioinformatic revealed that prominent was downregulate translation, potentially mediated through components insulin signaling pathway mammalian target rapamycin (mTOR), key regulator protein synthesis. Consistent analysis, reduced levels total phosphorylated mTOR, returned baseline after 2.5 recovery sleep. Our findings represent first they suggest detrimental may be by reductions synthesis via downregulation mTOR. Because mTOR activation are required long-term formation, our study improves understanding mechanisms underlying impairments induced deprivation.
Language: Английский
Citations
155SLEEP, Journal Year: 2017, Volume and Issue: unknown
Published: July 22, 2017
The metabolic impact of inadequate sleep has not been determined in healthy individuals outside laboratories. This study aims to investigate the duration on five syndrome components a adult cohort.A total 162121 adults aged 20-80 years (men 47.4%) MJ Health Database, who were obese and free from major diseases, recruited followed up 1996 2014. Sleep insomnia symptoms assessed by self-administered questionnaire. Incident cases identified follow-up medical examinations. Cox proportional hazard ratios (HRs) calculated for three categories "< 6 hours/day (short)," "6-8 (regular)," "> 8 (long)" with adjustment potential confounding factors. Analyses stratified assess whether modified association between syndrome.Compared regular duration, short significantly (p < .001) increased risk central obesity 12% (adjusted HR 1.12 [1.07-1.17]), elevated fasting glucose 6% 1.06 [1.03-1.09]), high blood pressure 8% 1.08 [1.04-1.13]), low high-density lipoprotein-cholesterol 7% 1.07 [1.03-1.11]), hypertriglyceridemia 9% 1.09 [1.05-1.13]), [1.05-1.13]). Long decreased 0.89 [0.84-0.94]) 0.93 [0.88-0.99]). Insomnia did modify effects duration.Sleep may be significant determinant health.
Language: Английский
Citations
123Sleep Medicine Clinics, Journal Year: 2020, Volume and Issue: 15(2), P. 319 - 340
Published: May 5, 2020
Language: Английский
Citations
120American Journal of Clinical Nutrition, Journal Year: 2012, Volume and Issue: 96(3), P. 492 - 497
Published: July 27, 2012
Language: Английский
Citations
118SLEEP, Journal Year: 2014, Volume and Issue: 37(8), P. 1327 - 1336
Published: July 31, 2014
Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loophelix family member e41) causal of short sleepers, who needed just 6 h sleep per night. We evaluated whether there were other variants this gene two well-phenotyped cohorts.Sequencing the gene, electroencephalographic data, and delta power analysis functional studies using cell-based luciferase.We identified new cohorts had either acute deprivation (n = 200) or chronic partial 217). One variant, Y362H, at another location same exon occurred one twin dizygotic pair was associated with reduced duration, less recovery following deprivation, fewer performance lapses during than homozygous twin. Both twins almost identical amounts non rapid eye movement (NREM) sleep. This variant ability to suppress CLOCK/BMAL1 NPAS2/BMAL1 transactivation vitro. Another exome no effect on response transactivation. Random mutagenesis number that affect its function.There are mutations BHLHE41. Mutations reduce total while maintaining NREM provide resistance effects loss. modify normal inhibition Thus, clock mechanisms likely involved setting length magnitude homeostasis.Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI. A novel is humans. SLEEP 2014;37(8):1327-1336.
Language: Английский
Citations
117Sleep Medicine, Journal Year: 2013, Volume and Issue: 14(3), P. 229 - 236
Published: Jan. 23, 2013
Language: Английский
Citations
114