Prevalence of sleep problems among medical students: a systematic review and meta-analysis DOI
Haitham Jahrami, Julia Dewald‐Kaufmann, MoezAlIslam E. Faris

et al.

Journal of Public Health, Journal Year: 2019, Volume and Issue: 28(5), P. 605 - 622

Published: April 5, 2019

Language: Английский

Sleep quality and associated factors among university students in Africa: a systematic review and meta-analysis study DOI Creative Commons
Girum Nakie, Girmaw Medfu Takelle, Gidey Rtbey

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: March 11, 2024

Background Poor sleep quality significantly impacts academic performance in university students. However, inconsistent and inconclusive results were found a study on among students several African nations. Therefore, this aimed to estimate the pooled prevalence associated factors of poor Africa. Methods The databases PubMed, Scopus, Cochrane Library, Science Direct, Journal Online, Google Scholar searched identify articles. A total 35 primary articles from 11 countries assessed included systematic review meta-analysis. Data extracted by using Microsoft Excel spreadsheet exported STATA version 14 for analysis. I 2 test was used assess statistical heterogeneity. random effect meta-analysis model employed with 95% confidence intervals. Funnel plots analysis Egger regression tests check presence publication bias. subgroup sensitivity done. Results 16,275 participants studies review. overall Africa 63.31% (95% CI: 56.91-65.71) = 97.2. shows that combined East, North, West, South 61.31 56.91-65.71), 62.23 54.07-70.39), 54.43 47.39-61.48), 69.59 50.39-88.80) respectively. Being stressed (AOR= 2.39; 1.63 3.51), second year 3.10; 2.30 4.19), use electronic device at bedtime 3.97 2.38 6.61)) having comorbid chronic illness (AOR 2.71; 1.08, 6.82) quality. Conclusion This there is high stressed, year, devices bedtime, addressing contributing implementing routine screenings are essential reduce burden Systematic Review Registration https://www.crd.york.ac.uk/prospero/ , identifier CRD42023493140.

Language: Английский

Citations

16

The relationship between sleep and wake habits and academic performance in medical students: a cross-sectional study DOI Creative Commons
Ahmed S. BaHammam, Abdulrahman Alaseem, Abdulmajeed Alzakri

et al.

BMC Medical Education, Journal Year: 2012, Volume and Issue: 12(1)

Published: Aug. 1, 2012

The relationship between the sleep/wake habits and academic performance of medical students is insufficiently addressed in literature. This study aimed to assess sleep duration with students. was conducted December 2009 January 2010 at College Medicine, King Saud University, included a systematic random sample healthy first (L1), second (L2) third (L3) levels. A self-administered questionnaire distributed demographics, schedule, habits, duration. Daytime sleepiness evaluated using Epworth Sleepiness Scale (ESS). School stratified as “excellent” (GPA ≥3.75/5) or “average” <3.75/5). final analysis 410 (males: 67%). One hundred fifteen (28%) had performance, 295 (72%) performance. group higher ESS score percentage who felt sleepy during class. In contrast, an earlier bedtime increased TST weekdays. Subjective feeling obtaining sufficient non-smoking were only independent predictors Decreased nocturnal time, late bedtimes weekdays weekends daytime are negatively associated

Language: Английский

Citations

183

Extreme Sleep Durations and Increased C-Reactive Protein: Effects of Sex and Ethnoracial Group DOI Open Access
Michael A. Grandner, Orfeu M. Buxton, Nicholas Jackson

et al.

SLEEP, Journal Year: 2013, Volume and Issue: 36(5), P. 769 - 779

Published: May 1, 2013

We hypothesize that extremes of sleep duration are associated with elevated C-reactive protein (CRP), a pro-inflammatory marker for cardiovascular disease risk. Cross-sectional. Population-based research. Nationally representative sample 2007-2008 National Health and Nutrition Examination Survey participants (n = 5,587 adults). None. Associations between CRP self-reported total time (TST) were examined. Explanatory models considered contributions sex, age, race/ethnicity, body mass index (BMI), BMI squared (BMI2). Models also explored the role insomnia symptoms, apnea, active medical illness, antidiabetic/antihypertensive treatment. Differential patterns among race/ethnicity groups examined using interactions stratified analyses. Nonlinear relationships TST assessed polynomial multinomial regression (< 5, 6, 7, 8, 9, > 9 h). Linear terms significant in all complete sample, notable differences by sex ethnoracial group. Overall, adjusted sociodemographics BMI, different observed non-Hispanic white (elevated < 5 h h), black/African-American 8 Hispanic/Latino Asian/ Other (higher lower 6 h) groups. Ethnoracial demonstrated patterning sex. In American adults, was extreme durations. Sex, disorders, comorbidity influenced these associations. Differences along dimensions should be future research on related disparities influencing cardiometabolic

Language: Английский

Citations

161

Sleep Duration and Diabetes Risk: Population Trends and Potential Mechanisms DOI
Michael A. Grandner, Azizi Seixas,

Safal Shetty

et al.

Current Diabetes Reports, Journal Year: 2016, Volume and Issue: 16(11)

Published: Sept. 23, 2016

Language: Английский

Citations

160

Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus DOI
Christopher G. Vecsey, Lucı́a Peixoto,

Jennifer Choi

et al.

Physiological Genomics, Journal Year: 2012, Volume and Issue: 44(20), P. 981 - 991

Published: Aug. 29, 2012

Sleep deprivation is a common problem of considerable health and economic impact in today's society. loss associated with deleterious effects on cognitive functions such as memory has high comorbidity many neurodegenerative neuropsychiatric disorders. Therefore, it crucial to understand the molecular basis effect sleep brain. In this study, we combined genome-wide traditional biological approaches determine cellular impacts mouse hippocampus, brain area for forms memory. Microarray analysis examining 5 h gene expression hippocampus found 533 genes altered expression. Bioinformatic revealed that prominent was downregulate translation, potentially mediated through components insulin signaling pathway mammalian target rapamycin (mTOR), key regulator protein synthesis. Consistent analysis, reduced levels total phosphorylated mTOR, returned baseline after 2.5 recovery sleep. Our findings represent first they suggest detrimental may be by reductions synthesis via downregulation mTOR. Because mTOR activation are required long-term formation, our study improves understanding mechanisms underlying impairments induced deprivation.

Language: Английский

Citations

155

Short Sleep Duration Increases Metabolic Impact in Healthy Adults: A Population-Based Cohort Study DOI Open Access
Han‐Bing Deng, Tony Tam, Benny Zee

et al.

SLEEP, Journal Year: 2017, Volume and Issue: unknown

Published: July 22, 2017

The metabolic impact of inadequate sleep has not been determined in healthy individuals outside laboratories. This study aims to investigate the duration on five syndrome components a adult cohort.A total 162121 adults aged 20-80 years (men 47.4%) MJ Health Database, who were obese and free from major diseases, recruited followed up 1996 2014. Sleep insomnia symptoms assessed by self-administered questionnaire. Incident cases identified follow-up medical examinations. Cox proportional hazard ratios (HRs) calculated for three categories "< 6 hours/day (short)," "6-8 (regular)," "> 8 (long)" with adjustment potential confounding factors. Analyses stratified assess whether modified association between syndrome.Compared regular duration, short significantly (p < .001) increased risk central obesity 12% (adjusted HR 1.12 [1.07-1.17]), elevated fasting glucose 6% 1.06 [1.03-1.09]), high blood pressure 8% 1.08 [1.04-1.13]), low high-density lipoprotein-cholesterol 7% 1.07 [1.03-1.11]), hypertriglyceridemia 9% 1.09 [1.05-1.13]), [1.05-1.13]). Long decreased 0.89 [0.84-0.94]) 0.93 [0.88-0.99]). Insomnia did modify effects duration.Sleep may be significant determinant health.

Language: Английский

Citations

123

Sleep, Health, and Society DOI
Michael A. Grandner

Sleep Medicine Clinics, Journal Year: 2020, Volume and Issue: 15(2), P. 319 - 340

Published: May 5, 2020

Language: Английский

Citations

120

Lifestyle determinants of the drive to eat: a meta-analysis DOI Creative Commons
Colin D. Chapman, Christian Benedict, Samantha J. Brooks

et al.

American Journal of Clinical Nutrition, Journal Year: 2012, Volume and Issue: 96(3), P. 492 - 497

Published: July 27, 2012

Language: Английский

Citations

118

A NovelBHLHE41Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans DOI Open Access
Renata Pellegrino, İbrahim Halil Kavaklı, Namni Goel

et al.

SLEEP, Journal Year: 2014, Volume and Issue: 37(8), P. 1327 - 1336

Published: July 31, 2014

Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loophelix family member e41) causal of short sleepers, who needed just 6 h sleep per night. We evaluated whether there were other variants this gene two well-phenotyped cohorts.Sequencing the gene, electroencephalographic data, and delta power analysis functional studies using cell-based luciferase.We identified new cohorts had either acute deprivation (n = 200) or chronic partial 217). One variant, Y362H, at another location same exon occurred one twin dizygotic pair was associated with reduced duration, less recovery following deprivation, fewer performance lapses during than homozygous twin. Both twins almost identical amounts non rapid eye movement (NREM) sleep. This variant ability to suppress CLOCK/BMAL1 NPAS2/BMAL1 transactivation vitro. Another exome no effect on response transactivation. Random mutagenesis number that affect its function.There are mutations BHLHE41. Mutations reduce total while maintaining NREM provide resistance effects loss. modify normal inhibition Thus, clock mechanisms likely involved setting length magnitude homeostasis.Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI. A novel is humans. SLEEP 2014;37(8):1327-1336.

Language: Английский

Citations

117

Sleep loss as risk factor for neurologic disorders: A review DOI
Jose‐Alberto Palma, Elena Urrestarazu,

Jorge Iriarte

et al.

Sleep Medicine, Journal Year: 2013, Volume and Issue: 14(3), P. 229 - 236

Published: Jan. 23, 2013

Language: Английский

Citations

114