Journal of Personalized Medicine,
Journal Year:
2022,
Volume and Issue:
12(12), P. 2070 - 2070
Published: Dec. 15, 2022
The
present
study
aims
to
provide
a
critical
overview
of
the
literature
on
relationships
between
post-acute
COVID-19
infection
and
cognitive
impairment,
highlighting
limitations
confounding
factors.
A
systematic
search
articles
published
from
1
January
2020
July
2022
was
performed
in
PubMed/Medline.
We
followed
Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses
(PRISMA)
guidelines.
Only
studies
using
validated
instruments
assessment
impairment
were
included.
Out
5515
screened
records,
72
met
inclusion
criteria.
available
evidence
revealed
presence
executive
functions,
speed
processing,
attention
memory
subjects
recovered
COVID-19.
However,
several
reviewed
should
be
highlighted:
most
small
samples,
not
stratified
by
severity
disease
age,
used
as
cross-sectional
or
short-term
longitudinal
design
provided
limited
different
domains.
Few
investigated
neurobiological
correlates
deficits
individuals
Further
with
an
adequate
methodological
are
needed
in-depth
characterization
Infectious Diseases,
Journal Year:
2021,
Volume and Issue:
53(10), P. 737 - 754
Published: May 22, 2021
Long
COVID
or
post-COVID-19
syndrome
first
gained
widespread
recognition
among
social
support
groups
and
later
in
scientific
medical
communities.
This
illness
is
poorly
understood
as
it
affects
COVID-19
survivors
at
all
levels
of
disease
severity,
even
younger
adults,
children,
those
not
hospitalized.
While
the
precise
definition
long
may
be
lacking,
most
common
symptoms
reported
many
studies
are
fatigue
dyspnoea
that
last
for
months
after
acute
COVID-19.
Other
persistent
include
cognitive
mental
impairments,
chest
joint
pains,
palpitations,
myalgia,
smell
taste
dysfunctions,
cough,
headache,
gastrointestinal
cardiac
issues.
Presently,
there
limited
literature
discussing
possible
pathophysiology,
risk
factors,
treatments
COVID,
which
current
review
aims
to
address.
In
brief,
driven
by
long-term
tissue
damage
(e.g.
lung,
brain,
heart)
pathological
inflammation
from
viral
persistence,
immune
dysregulation,
autoimmunity).
The
associated
factors
female
sex,
more
than
five
early
symptoms,
dyspnoea,
prior
psychiatric
disorders,
specific
biomarkers
D-dimer,
CRP,
lymphocyte
count),
although
research
required
substantiate
such
factors.
preliminary
evidence
suggests
personalized
rehabilitation
training
help
certain
cases,
therapeutic
drugs
repurposed
other
similar
conditions,
myalgic
encephalomyelitis
chronic
syndrome,
postural
orthostatic
tachycardia
mast
cell
activation
also
hold
potential.
sum,
this
hopes
provide
understanding
what
known
about
COVID.
International Journal of Clinical Practice,
Journal Year:
2021,
Volume and Issue:
75(10)
Published: May 12, 2021
To
identify,
systematically
evaluate
and
summarise
the
best
available
evidence
on
frequency
of
long
COVID-19
(post-acute
syndrome),
its
clinical
manifestations,
criteria
used
for
diagnosis.
Reviews in Medical Virology,
Journal Year:
2021,
Volume and Issue:
32(4)
Published: Dec. 9, 2021
Summary
The
effects
of
coronavirus
disease
2019
(COVID‐19),
a
highly
transmissible
infectious
respiratory
that
has
initiated
an
ongoing
pandemic
since
early
2020,
do
not
always
end
in
the
acute
phase.
Depending
on
study
referred,
about
10%–30%
(or
more)
COVID‐19
survivors
may
develop
long‐COVID
or
post‐COVID‐19
syndrome
(PCS),
characterised
by
persistent
symptoms
(most
commonly
fatigue,
dyspnoea,
and
cognitive
impairments)
lasting
for
3
months
more
after
COVID‐19.
While
pathophysiological
mechanisms
PCS
have
been
extensively
described
elsewhere,
subtypes
not.
Owing
to
its
multifaceted
nature,
this
review
proposes
characterises
six
based
existing
literature.
are
non‐severe
multi‐organ
sequelae
(NSC‐MOS),
pulmonary
fibrosis
(PFS),
myalgic
encephalomyelitis
chronic
fatigue
(ME/CFS),
postural
orthostatic
tachycardia
(POTS),
post‐intensive
care
(PICS)
medical
clinical
(MCS).
Original
studies
supporting
each
these
documented
review,
as
well
their
respective
potential
interventions.
Ultimately,
subtyping
proposed
herein
aims
provide
better
clarity
current
understanding
PCS.
European Respiratory Journal,
Journal Year:
2022,
Volume and Issue:
60(2), P. 2102174 - 2102174
Published: Feb. 10, 2022
Patients
diagnosed
with
coronavirus
disease
2019
(COVID-19)
associated
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
infection
frequently
experience
symptom
burden
post-acute
or
post-hospitalisation.
We
aimed
to
identify
optimal
strategies
for
follow-up
care
that
may
positively
impact
the
patient's
quality
of
life
(QoL).
A
European
Respiratory
Society
(ERS)
Task
Force
convened
and
prioritised
eight
clinical
questions.
targeted
search
literature
defined
timeline
“long
COVID”
as
1–6
months
post-infection
identified
evidence
in
patients.
Studies
meeting
inclusion
criteria
report
an
association
characteristics
persistent
symptoms,
thromboembolic
events
period,
evaluations
pulmonary
physiology
imaging.
Importantly,
this
statement
reviews
QoL
consequences,
burden,
disability
home
follow-up.
Overall,
patients
long
COVID
is
limited.
International Journal of Environmental Research and Public Health,
Journal Year:
2021,
Volume and Issue:
18(5), P. 2695 - 2695
Published: March 7, 2021
Background:
Severe
COVID-19
infection
often
leads
to
impairments
requiring
pulmonary
rehabilitation
(PR)
following
the
acute
phase.
Little
is
known
about
efficacy
of
PR
in
these
patients.
We
therefore
compared
post-COVID-19
patients
(PG)
referred
with
other
lung
diseases
(LG).
Methods:
99
PG
were
admitted
PR.
In
a
prospective
design,
results
collected
and
LG
2019
(n
=
419)
according
Functional
Independence
Measurement
(FIM),
Cumulative
Illness
Rating
Scale
(CIRS),
6-min
walk
test
(6-MWT),
duration
PR,
Feeling
Thermometer
(FT).
Results:
According
age,
sex,
CIRS,
both
groups
showed
no
significant
differences.
The
improvements
6-MWT
pre
post
comparison
on
average
180
(±101)
meters
for
102
(±89)
(p
<
0.001).
FT
enhancement
21
(±14)
points
17
(±16)
0.039),
while
FIM
significantly
increased
by
11
(±10)
7
(±8)
Conclusions:
Comprehensive
very
effective
FIM,
FT.
Therefore,
we
recommend
severe
infections.
