World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(3), P. 140 - 179
Published: March 16, 2024
This
review
paper
highlights
the
role
of
phytocannabinoids
in
controlling
triple-negative
breast
cancer
(TNBC).
Triple-negative
(TNBC)
is
a
specific
subtype
that
does
not
express
estrogen
receptor
(ER),
progesterone
(PR),
or
human
epidermal
growth
factor
2
(HER-2),
which
has
clinical
features
include
high
invasiveness,
metastatic
potential,
proneness
to
relapse,
and
poor
prognosis.
TNBC
one
most
aggressive
subtypes
often
associated
with
patient
outcomes
because
development
metastases
secondary
organisms
like
brain,
bone,
lungs.
kind
have
any
receptors
are
commonly
found
cancer.
The
highest
number
cases
been
recorded
India.
Currently,
highly
prevalent
among
Indian
women
develops
approximately
20%
43%
all
patients
an
malignancy
requires
effective
targeted
drug
therapy.
Patients
develop
metastasis
recurrence
over
time
reduced
survival
compared
other
Pre-clinical
studies
demonstrated
exert
important
antitumor
properties
main
subtypes,
particularly
TNBC,
where
different
synthetic
cannabinoids
shown
interesting
therapeutic
actions.
Neither
CBD
nor
THC
universally
efficacious
reducing
cell
viability.
Focusing
on
vitro
studies,
effect
viability
ranges
from
no
effect,
modest
reduction,
significant
cytotoxicity
depending
concentrations,
lines,
conditions,
performed
assays,
exposure.
However,
it
should
also
be
noted
research
into
efficacy,
dosage
safety
tumor
therapy
still
long
way
go,
especially
regard
trials
conducted,
through
alone
benefits
advantages
for
but
possible
risks
can
defined.
Biochar,
Journal Year:
2025,
Volume and Issue:
7(1)
Published: Jan. 14, 2025
Abstract
Over
the
past
10–15
years,
biochar
has
garnered
significant
global
attention
in
agriculture
and
environmental
science.
While
most
research
focused
on
benefits
of
application
soil
enhancement,
water
quality
improvement,
climate
change
mitigation,
potential
risks
associated
with
its
use
have
often
been
overlooked.
This
oversight
is
critical,
as
fate
contingent
upon
understanding
these
risks.
Once
released
into
environment,
can
interact
media,
potentially
releasing
pollutants
threatening
ecosystems.
Therefore,
it
essential
to
evaluate
unintended
health
during
production
select
appropriate
types
for
sustainable
development.
review
was
conducted
by
systematically
analyzing
synthesizing
relevant
studies
from
Web
Science,
focusing
recent
advancements
key
debates
field.
It
categorizes
endogenous
exogenous
based
source
carried
biochar.
The
analyzes
detail
impacts
raw
materials,
preparation
processes,
scenarios
Furthermore,
provides
a
thorough
overview
adverse
effects
animals,
plants,
microorganisms,
human
health,
elucidating
mechanisms
pollutant
release,
aging,
nano-effects
geochemical
processes
involving
Additionally,
this
summarizes
risk
assessment
methods
biochar,
providing
reference
safe
development
biochar-related
research.
Graphical
World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(2), P. 170 - 183
Published: Feb. 14, 2024
Cannabis
has
been
used
for
thousands
of
years
recreational,
medicinal,
or
religious
purposes
and
the
therapeutic
potential
medicinal
was
demonstrated
in
various
medical
conditions.
The
legalization
is
an
important
source
economic
growth
as
it
contributes
to
growing
revenue
tax,
creation
new
workplaces.
maturity
market
varies
across
globe
mainly
due
differing
legal
environments
public
attitudes
towards
Cannabis.
Some
countries
such
Canada
United
States
have
adopted
fully
regulated
frameworks
that
allow
cultivation,
consumption,
retail
distribution
products.
Uruguay
became
first
country
world
legalize
production,
consumption
cannabis
2013.
USA
experiencing
rapid
country's
recreational
use.
Regulations
can
also
differ
regarding
how
used.
However,
use,
marketing
Medical
sativa
(drug
Marijuana
type
)
banned
prohibited
India
presence
high
levels
psychoactive
principle
THC
(Narcotic
drug).
On
other
hand,
Industrial
(seed
fiber
type)
Hemp
legalized
2021
by
Food
Safety
Standards
Authority
(FSSAI),
Government
India,
New
Delhi.
In
Azerbaijan,
not
available
Recreational
marijuana
are
illegal
Azerbaijan.
China.
There
still
a
huge
prejudice
society
about
its
this
scenario
changing,
social
resistance
decreasing
use
(Hemp)
predicted
experience
substantial
growth,
with
projections
indicating
will
reach
₹US$100.80m
2024.
worldwide
projected
US$60.79bn
global
size
expected
USD
73.6
billion
2027
anticipated
expand
at
CAGR
18.1%
during
forecast
period.
International Journal of Science and Research Archive,
Journal Year:
2024,
Volume and Issue:
11(1), P. 2502 - 2539
Published: Feb. 28, 2024
This
review
paper
has
highlighted
a
list
of
plants
containing
active
phytochemicals
with
anticancer
potential,
as
well
data
supporting
their
use
in
cancer
therapy,
animal
models,
and
pharmacological
properties.
Cancer
is
among
the
leading
causes
morbidity
mortality
worldwide.
disease
characterized
by
abnormal
cell
division
proliferation
that
result
from
disruption
molecular
signals
control
these
processes.
abnormal,
uncontrolled
cells
body.
The
when
malignant,
invade
various
parts
body
through
bloodstream.
spread
its
or
tissue
origin
to
another
healthy
part
tissues
organs
called
metastasis.
Some
regular
characteristics
cancers
are
apoptosis,
angiogenesis,
multiple
replication,
growth
signal
production,
insensitivity
anti-growth
These
features
make
have
continuous
growth,
long
time
survival
potential
normal
cells.
Moreover,
if
activities
not
blocked,
will
continue
increase,
overwhelm
finally
kill
patient
cancer.
Oncology
study
An
oncologist
doctor
who
treats
provides
medical
care
for
person
diagnosed
may
also
be
specialist.
Today,
despite
considerable
efforts,
still
remains
an
aggressive
killer
success
rate
therapies
diminished
toxicities,
drug
resistance,
recurrence
treatment
failure.
A
significant
challenge
associated
much
art
it
science.
Therefore,
there
constant
demand
develop
new,
effective,
affordable
drugs.
Several
factors,
such
environmental
habitual
activities,
genetic
etc.,
responsible
Many
patients
seek
alternative
and/or
complementary
treatments
because
high
death
linked
adverse
side
effects
chemotherapy,
radiation
immunotherapy,
surgery,
stem
therapy.
Medicinal
could
possess
effective
compounds
used
adjuvants
existing
chemotherapy
improve
efficacy
reduce
drug-induced
toxicity;
chemotherapy-induced
nausea
vomiting
patients’
quality
life.
Cell
caused
whole
plant
extracts
via
apoptosis.
However,
majority
been
researched
prevention
rather
than
treatment,
resulting
low
uptake
practice.
Prevention
certainly
attractive
management
strategy.
Thus
might
possible
process
carcinogenesis
along
lifestyle.
Magna Scientia Advanced Research and Reviews,
Journal Year:
2024,
Volume and Issue:
10(1), P. 052 - 085
Published: Jan. 18, 2024
Food-borne
illnesses
and
diseases
are
major
threats
to
human
health.
Common
food
borne
pathogens
include
bacteria
such
as
Escherichia
coli
Serogroup
(O157),
Bacillus
cereus,
Clostridium
botulinum,
Campylobacter
sp.,
C.
perfringens,
some
Listeria
monocytogenes,
Salmonella
spp.,
Shigella
Staphylococcus
aureus,
Vibrio
spp.
etc.
Pathogenic
E.
infection
usually
causes
severe
diarrhea.
is
the
most
common
cause
of
acute
urinary
tract
infections
well
sepsis.
Diarrheagenic
pathotypes
can
be
passed
in
feces
humans
other
animals.
Safeguarding
public
health
during
mass
gatherings
a
big
challenge.
Despite
recent
advances
preservation
techniques
safety,
significant
disease
outbreaks
linked
bacteria,
fungi,
viruses
still
occur
worldwide
indicating
that
these
constitute
risks
However,
at
present
conventional
method
for
detection
requires
several
days,
especially
cases
where
concentrations
low.
Enrichment
commonly
used
bacterial
isolation
increase
cell
counts
target
bacteria.
traditional
culturing
also
slow
laborious
process
requiring
series
steps
may
require
use
adjunct
methods
(e.g.
biochemical,
serological,
nucleic
acid-based
conclusive
identification)
take
up
week
The
culture-based
approaches
coupled
with
PCR,
immunoassays,
bacteriophages,
NGS,
Biosensors,
MALDI
TOF
MS
increasingly
being
identification
pathogens.
Nucleic
Real-Time
PCR
vPCR
combined
sequencing
more
widely
than
immunoassay
NGS-based
pathogen
detection.
Nanobiotechnology
latest
approach
Bacteriophages
one
unique
biological
entity
showed
excellent
host
selectivity
have
been
actively
recognition
probes
Antibiotics
efficient,
powerful,
treatment
against
pathogenic
coli.
Other
ways
treat
or
prevent
contamination,
probiotics,
antimicrobial
nanoparticles,
radiation
had
reported.
World Journal of Advanced Research and Reviews,
Journal Year:
2023,
Volume and Issue:
20(1), P. 715 - 725
Published: Oct. 22, 2023
This
review
paper
updates
the
benefits
of
using
hemp
fibre
for
production
plastic.
Traditional
fossil-fuel
based
plastic
emits
massive
levels
greenhouse
gasses,
and
material
can
take
hundreds
years
to
break
down.
Traditionally,
plastics
are
made
from
petroleum-based
compounds,
which
release
toxic
gases
into
atmosphere.
Petroleum-based
its
by-product
have
a
devastating
effect
on
land,
water,
wildlife.
Biodegradable
produced
petro-chemicals
just
like
conventional
except
some
additives
included
in
their
manufacturing
helps
them
there
fast
degradation.
Hemp
is
type
biodegradable
fibres,
has
sufficiently
high
cellulose
concentration
polymers.
The
resulting
fully
recyclable.
It
then
be
processed
various
products,
including
packaging,
consumer
goods,
automotive
parts,
more
plastics.
100%
biodegradable,
better
alternative
synthetic
also
lightweight,
with
an
impressively
density
weight
ratio.
makes
potentially
good
making
lightweight
components
car
aerospace
industry.
Conversely,
minimize
effect.
offers
great
thermal,
UV,
dimensional
stability.
Some
types
resistant
flame.
solely
extracted
plant
therefore,
causes
no
toxicity
during
production.
World Journal of Biology Pharmacy and Health Sciences,
Journal Year:
2024,
Volume and Issue:
17(2), P. 253 - 296
Published: Feb. 20, 2024
This
litrature
review
paper
highlights
the
role
of
phytocannabinoids
in
controlling
cervical
cancer.
Cervical
cancer
is
one
leading
causes
death
among
females
worldwide.
(CC)
a
malignant
form
tumor
which
originates
cervix.
cancer,
develops
woman’s
cervix,
second-most
common
women
India
The
causative
agent
persistent
infection
with
high-risk
subtypes
Human
Papillomavirus
(HPV)
and
E5,
E6
E7
viral
onco-proteins
cooperate
host
factors
to
induce
maintain
phenotype.
papillomavirus
responsible
for
subclinical/clinical
lesions
HPV
types
16
18
are
most
identified
invasive
Currently,
recommended
therapeutic
regimens
include
chemotherapy,
radiation
therapy
either
alone
or
combination
surgical
interventions.
However,
they
present
several
limitations
including
side
effects
ineffectiveness.
Medicinal
plants
Cannabis
sativa
have
been
used
decades
health
benefits
treat
different
diseases
has
thousands
years
recreational,
medicinal,
religious
purposes.
Phytocannabinoids
cannabinoids
that
occur
naturally
cannabis
plant.
two
well
known
their
properties
are,
Δ9-tetrahydrocannabinol
(THC)
Cannabidiol
(CBD).
hold
big
promise
therapy.
there
need
understand
more
about
Endocannabinoid
system
(ECS)
normal
human
physiology
transformations.
Molecular
mechanisms
regulation
anticancer
also
be
clarified.
treatment
durations
existing
trials
concern.
Future
epidemiological
clinical
studies
required
further
assess
herbal
medicines
prevention
In
addition,
preclinical
trial
evaluations
not
specifically
conducted,
so
investigations
related
this
warranted.
Therefore,
immunization
programme
best
ideal
solution
eradication
Nitrogen,
Journal Year:
2024,
Volume and Issue:
5(3), P. 624 - 654
Published: July 18, 2024
Hemp
(Cannabis
sativa
L.),
renowned
for
its
applications
in
environmental,
industrial,
and
medicinal
fields,
is
critically
evaluated
this
comprehensive
review
focusing
on
the
impacts
of
chemical
organic
fertilizers
cultivation.
As
hemp
re-emerges
as
a
crop
economic
significance,
choice
between
fertilization
methods
plays
crucial
role
determining
not
only
yield
but
also
quality
sustainability
production.
This
article
examines
botanical
characteristics
hemp,
optimal
growth
conditions,
essential
biochemical
processes
A
detailed
comparative
analysis
provided,
revealing
that
fertilizers,
while
increasing
by
up
to
20%
compared
options,
may
compromise
concentration
key
phytochemicals
such
cannabidiol
approximately
10%,
highlighting
trade-off
product
quality.
The
presents
quantitative
assessments
nitrogen
(N),
phosphorus
(P),
potassium
(K)
from
both
fertilizer
types,
noting
K
significantly
influences
synthesis
terpenes
cannabinoids,
making
it
most
impactful
element
context
aromatic
varieties.
Optimal
rates
timing
application
these
nutrients
are
discussed,
with
focus
maximizing
efficiency
during
flowering
stage,
where
nutrient
uptake
directly
correlates
cannabinoid
Furthermore,
challenges
associated
U.S.
industrial
market
addressed,
reducing
production
costs
improving
processing
infrastructure
sustaining
industry
growth,
especially
given
slow
expansion
fiber
markets
due
bottlenecks.
concludes
offer
immediate
agronomic
benefits,
transitioning
towards
practices
long-term
environmental
viability.
future
industry,
promising,
will
depend
heavily
advancements
genetic
engineering,
management
strategies,
regulatory
frameworks
better
support
sustainable
cultivation
practices.
nuanced
approach
vital
navigate
complex
trade-offs
productivity,
health,
viability
global
market.
Magna Scientia Advanced Research and Reviews,
Journal Year:
2023,
Volume and Issue:
9(2), P. 022 - 035
Published: Nov. 12, 2023
This
review
paper
highlights
the
production
of
biodiesel
from
hemp
seed
oil
via
transesterification
reaction.
Hemp
seeds
present
a
viable
feedstock
option
for
production.
is
demonstrated
by
plants
high
yield,
ability
to
grow
on
infertile
soil,
resilience
disease
and
bugs.
performs
well
in
blends.
yield
was
calculated
at
207
gallons/ha.
higher
than
rapeseed
soybeans
oils
but
lower
that
palm
oil.
can
meet
ASTM
D6751
EN
14214
requirements.
exhibit
poor
kinematic
viscosity
oxidation
stability.
However,
this
easily
be
improved
with
use
additives.
Dilution/blending,
micro-emulsification,
pyrolysis,
trans-esterification
are
four
techniques
applied
solve
problems
encountered
fuel
viscosity.
provides
substantial
environmental
benefits.
The
amount
emission
reduction
corresponds
roughly
blend
rating
fuel.
may
used
an
alternative
highly
controversial
produced
faces
many
perception
legal
challenges
prevent
wide-scale
remains
niche
crop
food
supply
chains,
rendering
it
prohibitively
expensive
as
Legalization
increased
improve
cost
producing
subsequently
biodiesel.
International Journal of Biological and Pharmaceutical Sciences Archive,
Journal Year:
2023,
Volume and Issue:
6(2), P. 110 - 133
Published: Nov. 21, 2023
This
review
paper
highlights
the
production
of
biodiesel
from
different
plant
based
feedstocks
via
transesterification
process.
Biodiesel
is
a
renewable,
non-toxic,
environment-friendly
and
an
economically
feasible
option
to
tackle
depleting
fossil
fuels
its
negative
environmental
impact.
in
general
possess
higher
kinematic
viscosity
density
than
conventional
diesel.
However,
because
food
security
concerns,
use
edible
oil
criticized
globally.
Non-edible
oils,
waste
cooking
industry
byproducts
are
suggested
as
effective
nonedible
feedstock
does
not
compete
with
human
consumption.
High-potential
second-generation
for
uses
waist
oil,
acid
animal
tallow.
Non
crops
India
yellow
oleander
(Cascabela
thevetia),
Pongamia
(Pongamia
pinnata),
Jatropha
curcas,
Mahua
(Madhuca
longifolia),
Candlenut
(Aleurites
moluccanus),
Rubber
(Hevea
brasiliensis),
Soapnut
(Sapindus
mukorossi),
Jojoba
(Simmondsia
chinensis),
Tobacco
(Nicotiana
tabacum),
Neem
(Azadirachta
indica),
Karanja
(Millettia
Castor
(Ricinus
communis),
Polanga
(Calophyllum
inophyllum
L),
Cotton
(Gossypium),
Kusum
(Carthamus
tinctorius),
Yellow
Sea
mango
(Cerbera
odollam),
Tung
(Vernicia
fordii),
Bottle
tree
(Brachychiton
rupestris).
sustainable
liquid
bio-energy
resource
that
might
be
used
replace
diesel
fuel.
Despite
having
numerous
advantages
over
diesel,
still
struggling
various
reasons
challenges
like
availability,
high
pricing,
operational
hurdles,
supply-chain
management
challenges.
Open Access Research Journal of Biology and Pharmacy,
Journal Year:
2024,
Volume and Issue:
10(2), P. 028 - 071
Published: March 23, 2024
This
review
paper
highlights
and
updates
the
role
of
plant
based
inhibitors
in
controlling
triple-negative
breast
cancer
(TNBC)
via
blocking
TNBC
signalling
pathways.
Breast
is
most
common
women.
There
are
several
identified
types,
among
which
fatal
for
patients.
Conventionally,
defined
by
lack
estrogen
receptor
(ER),
progesterone
(PR),
human
epidermal
2
(HER2)
cells.
It
well-known
its
metastatic,
aggressive
characteristics
poor
outcome
clinic.
Till
today,
treatment
patients
still
a
challenging
task
due
to
absence
appropriate
targets
drugs.
Despite
successes
emerging
targeted
therapies,
relapse,
recurrence,
therapy
failure
rates
significantly
outpace
other
subtypes
cancer.
Mounting
evidence
suggests
an
accumulation
resistant,
Cancer
Stem
Cell
(CSC)
populations
within
TNBCs
contributes
clinical
outcomes.
These
Cells
enriched
compared
non-TNBC
cancers.
Approximately
60%
drugs
currently
used
have
been
isolated
from
natural
products.
Natural
products
treasure
house
development
novel
anticancer
Many
plant-derived
compounds
anti-cancer
properties,
including
berberine
quercetin,
formononetin,
calycosin,
polyphenols,
bioflavonoids,
carotene,
vitamins,
andminerals.
compounds,
vinka
alkaloids,
vinblastine
vincristine,
luteolin,
α-mangostin,
piperine,
silibinin,
apigenin,
fisetin,
resveratrol,
genistein,
10-gingerol,
chalcones,
curcumin,
epigallocatechin
gallate,
cyanidin-3-O-glucoside,
glycyrrhizin,
shown
especially
TNBCs.
Therefore,
more
trial
data
warranted
further
evaluation
extracts