Exploring the plant-derived bioactive substances as antidiabetic agent: An extensive review

Biomedicine & Pharmacotherapy, Journal Year: 2022, Volume and Issue: 152, P. 113217 - 113217

Published: June 6, 2022

Diabetes mellitus (DM) is a metabolic syndrome. has become more common in recent years. Chemically generated drugs are used to lessen the effects of DM and its following repercussions due unpleasant side such as weight gain, gastrointestinal issues, heart failure. On other hand, medicinal plants could be good source anti-diabetic medications. This article aims determine any plant matrix's positive potential. Food restriction, physical activity, use antidiabetic plant-derived chemicals all being promoted effective ways manage diabetes because they less expensive have fewer or no effects. review focuses on plants, along with their bioactive constituent, chemically characterization, plant-based diets for management. There minimal scientific data about mechanism action product been found. The purpose this highlight compounds that properties. It also provides researchers may build future strategies, identifying promising molecules make management easier.

Language: Английский

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Green Synthesis of Nanoparticles and Their Energy Storage, Environmental, and Biomedical Applications

Crystals, Journal Year: 2023, Volume and Issue: 13(11), P. 1576 - 1576

Published: Nov. 8, 2023

Green synthesis offers a superior alternative to traditional methods for producing metal and oxide nanoparticles. This approach is not only benign safe but also cost-effective, scalable, straightforward, operating under ambient conditions. Notable metals nanoparticles, such as manganese oxides, iron silver, gold, have been produced using various bio-reductants derived from plant extracts. These biological agents expedite the reduction process stabilize serving dual roles reducing capping agents. review presents green of nanoparticles (NPs) obtained biogenic wastes The green-synthesized nanostructured MnO2 are evaluated potential photocatalyst water treatment an electrode material in lithium-ion batteries supercapacitors. green-derived examined promising antioxidant, anti-inflammatory, anti-diabetic Additionally, this discusses precious specifically silver (Ag NPs) gold (Au NPs), highlighting their medical applications areas like antiviral treatments cancer therapy.

Language: Английский

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Fungal Mushrooms: A Natural Compound With Therapeutic Applications

Frontiers in Pharmacology, Journal Year: 2022, Volume and Issue: 13

Published: July 13, 2022

Fungi are extremely diverse in terms of morphology, ecology, metabolism, and phylogeny. Approximately, 130 medicinal activities like antitumor, immunomodulation, antioxidant, radical scavenging, cardioprotective antiviral actions assumed to be produced by the various varieties mushrooms. The polysaccharides, present mushrooms β-glucans, micronutrients, antioxidants glycoproteins, triterpenoids, flavonoids, ergosterols can help establish natural resistance against infections toxins.. Clinical trials have been performed on Agaricus blazei Murrill Kyowa for their anticancer effect , A. its antihypertensive effects, some other had also evaluated neurological effects. human evaluation dose studies toxicity was from literature number All were found safe at a 2000 mg/kg but with mild side safety therapeutic effectiveness fungal shifted interest biotechnologists toward nanobiotechnology as drug delivery system due vast advantages nanotechnology systems. In complement vital nutritional significance mushrooms, numerous species identified sources bioactive chemicals. Moreover, there unanswered queries regarding safety, efficacy, critical issues that affect future mushroom medicine development, could jeopardize usage twenty-first century.

Language: Английский

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A review on the green synthesis of nanoparticles, their biological applications, and photocatalytic efficiency against environmental toxins

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(27), P. 69796 - 69823

Published: May 12, 2023

Language: Английский

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Green Synthesis of Nanoparticles: A Biological Approach

IntechOpen eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 11, 2023

Nanoparticles are often associated with their small size and numerous applications. However, the synthesis process is equally important as it determines properties of nanoparticles. While traditional nanoparticle methods require use hazardous chemicals high-energy consumption, green offers a sustainable, cost-effective, environmentally friendly alternative. This approach utilizes natural resources biologically active compounds that can act reducing, stabilizing, or capping agents in one-step Green advantages, including development processes minimal environmental impact improved safety for synthesis. Overall, nanoparticles using chemistry promising sustainable efficient production. chapter provides general overview nanoparticles, applications, synthesis, highlights various biological used these factors affecting

Language: Английский

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Green synthesis of metal oxide nanoparticles, and their various applications

Journal of Hazardous Materials Advances, Journal Year: 2024, Volume and Issue: 13, P. 100401 - 100401

Published: Jan. 13, 2024

Bio-synthesized metal oxide (MeO) nanoparticles (NPs) have triggered a huge global research interest owing to their advancement and various environmental remediation, personal care products, medical, energy, sensing, water treatment applications. They demonstrate developing assets in industries, remarkably with heightened physicochemical, optical, mechanical, electronic attributes. The physical chemical routes been sticking point the production of MeO NPs, natural risks linked utilizing these approaches. growth NPs via biologic method employing plants microorganisms as precursor material for metal-ions (MIs) reduction stabilization has focus scientists recent years. Hence, this review, comprehensive brief bio-synthesis approaches using plant extracts (PEs) microorganism components well factors affecting bio-production applications toxicity were considered.

Language: Английский

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Selenium Nanoparticles: Green Synthesis and Biomedical Application

Molecules, Journal Year: 2023, Volume and Issue: 28(24), P. 8125 - 8125

Published: Dec. 15, 2023

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. "Green" synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers biosynthesis mechanism of bacteria, fungi, algae, plants, including role various biological substances processes reducing selenium compounds SeNPs their further packaging. Modern information approaches possible biomedical use presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, other properties, as well mechanisms these processes, that have important potential therapeutic value.

Language: Английский

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Revolutionizing agriculture with nanotechnology: Innovative approaches in fungal disease management and plant health monitoring

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 928, P. 172473 - 172473

Published: April 13, 2024

Language: Английский

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Innovative ultrasound assisted synthesis of sponge like cerium dioxide nanostructure using Rosa Damascena extract and its efficient performance for cancer therapy

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 6, 2025

In this work, cerium dioxide nanostructures were synthesized in an easy sonochemical way. CeO2 nanoparticles have received much attention nanotechnology. CeO2NPs, exhibit biomimetic properties depending on their size, ratio of valency surface, and the ambient physico-chemical properties. Nanomedicine has emerged as a promising avenue for targeted cancer therapy, aiming to develop innovative approaches with improved efficacy reduced side effects. Here, production nanostructures, new natural capping agent called Rosa Damascena extract was utilized, well ceric ammonium nitrate metal precursor. The results characterization oxide sample fabricated presence demonstrated that sponge-like morphology, which pure cubic crystal phase, formed. cytotoxicity effect NPs glioblastoma neuroblastoma cell lines (T98, SHSY5Y) studied using MTT test; exhibited effects T98 SHSY5Y lines, compared control. cytotoxic can be due plant secondary metabolites involved green synthesis NPs. Consequently, revealed acceptable inhibitory impact upon lines.

Language: Английский

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Gelatin/PLA-loaded gold nanocomposites synthesis using Syzygium cumini fruit extract and their antioxidant, antibacterial, anti-inflammatory, antidiabetic and anti-Alzheimer’s activities

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 15, 2025

Nanotechnology has experienced significant advancements, attracting considerable attention in various biomedical applications. This innovative study synthesizes and characterizes Ge/PLA/AuNCs (gelatin/PLA/gold nanocomposites) using Syzygium cumini extract to evaluate their The UV–Visible spectroscopy results an absorption peak at 534 nm were primarily confirmed by synthesis. FTIR spectrum showed functional groups the XRD patterns crystalline shape structure of nanocomposites. FESEM HRTEM a oval with average particle size 21 nm. Ge/PLA/AuNC's remarkable antioxidant activity, as evidenced DPPH (70.84 ± 1.64%), ABTS activity (86.17 1.96%), reducing power (78.42 1.48%) concentration 100 μg/mL was observed. zone inhibition against Staphylococcus aureus (19.45 0.89 mm) Echericia coli (20.83 0.97 revealed excellent antibacterial Ge/PLA/AuNCs. anti-diabetic supported α-amylase (82.56 1.49%) α-glucosidase (80.27 1.57%). anti-Alzheimer AChE (76.37 1.18%) BChE (85.94 1.38%) enzymes. In vivo studies zebrafish embryos that have biocompatibility nontoxicity. SH-SY5Y cell line demonstrated improved viability (95.27 1.62%) enhanced neuronal growth following treatment. conclusion, present highlights cost-effective non-toxic properties Furthermore, it presents attractive promising approach for future

Language: Английский

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