Studies
in
the
field
of
experimental
hypnosis
highlighted
role
hypnotizability
physiological
variability
general
population.
It
is
associated,
fact,
with
a
few
differences
which
are
observable
ordinary
state
consciousness
and
absence
suggestions.
The
aim
present
scoping
review
summarizing
them,
indicate
their
relevance
to
neural
mechanisms
prognosis
treatment
medical
conditions.
Individuals
high,
medium
low
scores
display
different
cerebral
functional
–
i.e.,
equivalence
between
imagery
perception/action,
excitability
motor
cortex,
interoceptive
accuracy
-
possibly
related
brain
structural
characteristics
-,
control
blood
supply
at
peripheral
level,
likely
due
availability
endothelial
nitric
oxide.
These
reviewed
support
idea
participation
hypnotic
behaviour
prognostic
therapeutic
usefulness
Molecular Psychiatry,
Journal Year:
2023,
Volume and Issue:
28(9), P. 3625 - 3637
Published: Sept. 1, 2023
Abstract
The
human
body
harbors
a
diverse
ecosystem
of
microorganisms,
including
bacteria,
viruses,
and
fungi,
collectively
known
as
the
microbiota.
Current
research
is
increasingly
focusing
on
potential
association
between
microbiota
various
neuropsychiatric
disorders.
resides
in
parts
body,
such
oral
cavity,
nasal
passages,
lungs,
gut,
skin,
bladder,
vagina.
gut
gastrointestinal
tract
has
received
particular
attention
due
to
its
high
abundance
role
psychiatric
neurodegenerative
However,
presents
other
tissues,
though
less
abundant,
also
plays
crucial
immune
system
homeostasis,
thus
influencing
development
progression
For
example,
imbalance
associated
periodontitis
might
increase
risk
for
Additionally,
studies
using
postmortem
brain
samples
have
detected
widespread
presence
bacteria
brains
patients
with
Alzheimer’s
disease.
This
article
provides
an
overview
emerging
host
disorders
discusses
future
directions,
underlying
biological
mechanisms,
reliable
biomarkers
microbiota,
microbiota-targeted
interventions,
this
field.
Advances in Therapy,
Journal Year:
2024,
Volume and Issue:
41(3), P. 901 - 914
Published: Jan. 30, 2024
Dysbiosis
corresponds
to
the
disruption
of
a
formerly
stable,
functionally
complete
microbiota.
In
gut,
this
imbalance
can
lead
adverse
health
outcomes
in
both
short
and
long
terms,
with
potential
increase
lifetime
risks
various
noncommunicable
diseases
disorders
such
as
atopy
(like
asthma),
inflammatory
bowel
disease,
neurological
disorders,
even
behavioural
psychological
disorders.
Although
antibiotics
are
highly
effective
reducing
morbidity
mortality
infectious
diseases,
antibiotic-associated
diarrhoea
is
common,
non-negligible
clinical
sign
gut
dysbiosis
(and
only
visible
one).
Re-establishment
normal
(functional)
microbiota
promoted
by
completion
clinically
indicated
course
antibiotics,
removal
any
other
perturbing
external
factors,
passage
time
(i.e.
recovery
through
microbiota's
natural
resilience),
appropriate
nutritional
support,
and-in
selected
cases-the
addition
probiotics.
Systematic
reviews
meta-analyses
trials
have
confirmed
strain-specific
efficacy
some
probiotics
(notably
yeast
Saccharomyces
boulardii
CNCM
I-745
bacterium
Lactobacillus
rhamnosus
GG)
treatment
and/or
prevention
children
adults.
Unusually
for
probiotic,
S.
eukaryote
not
therefore
directly
affected
antibiotics-making
it
suitable
administration
cases
diarrhoea.
A
robust
body
evidence
from
shows
that
timely
an
adequately
dosed
probiotic
(upon
initiation
antibiotic
or
within
48
h)
help
prevent
resolve
consequences
(such
diarrhoea)
promote
resilience
return
pre-antibiotic
state.
focus
on
prescription
evidence-based,
should
limit
unjustified
potentially
ineffective
self-medication.
Pathogens,
Journal Year:
2024,
Volume and Issue:
13(3), P. 195 - 195
Published: Feb. 23, 2024
Recent
studies
have
suggested
that
periodontal
disease
and
alterations
in
the
oral
microbiome
may
be
associated
with
cognitive
decline
Alzheimer’s
(AD)
development.
Here,
we
report
a
case-control
study
of
microbiota
diversity
AD
patients
compared
to
healthy
seniors
from
Central
Asia.
We
characterized
bacterial
taxonomic
composition
(n
=
64)
group
71)
using
16S
ribosomal
RNA
sequencing.
According
our
results,
has
higher
microbial
diversity,
an
increase
Firmicutes
decrease
Bacteroidetes
group.
LEfSe
analysis
showed
specific
differences
at
genus
level
both
groups.
A
region-based
compartment
was
also
performed,
were
identified,
along
absence
richness
on
functional
side.
Noteworthy
findings
demonstrated
periodontitis-associated
bacteria
Distinct
revealed
distribution
metabolic
pathways
between
two
Our
confirms
is
altered
AD.
However,
comprehensive
picture
complete
requires
further
investigation.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(8), P. 1732 - 1732
Published: Aug. 22, 2024
Stroke
represents
a
significant
global
health
burden,
with
substantial
impact
on
mortality,
morbidity,
and
long-term
disability.
The
examination
of
stroke
biomarkers,
particularly
the
oral
microbiome,
offers
promising
avenue
for
advancing
our
understanding
factors
that
contribute
to
risk
developing
strategies
mitigate
risk.
This
review
highlights
correlations
between
diseases,
such
as
periodontitis
caries,
onset
stroke.
Periodontal
pathogens
within
microbiome
have
been
identified
contributing
factor
in
exacerbation
stroke,
including
obesity,
dyslipidemia,
atherosclerosis,
hypertension,
endothelial
dysfunction.
alteration
may
these
conditions,
emphasizing
vital
role
prevention
cardiovascular
disease.
integration
dental
medical
practices
enhancing
efforts
improving
patient
outcomes.
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(1), P. 122 - 122
Published: Jan. 9, 2025
Alzheimer's
disease
(AD),
the
most
common
form
of
dementia,
is
a
progressive
neurodegenerative
disorder
that
profoundly
impacts
cognitive
function
and
nervous
system.
Emerging
evidence
highlights
pivotal
roles
iron
homeostasis
dysregulation
microbial
inflammatory
factors
in
oral
gut
microbiome
as
potential
contributors
to
pathogenesis
AD.
Iron
disruption
can
result
excessive
intracellular
accumulation,
promoting
generation
reactive
oxygen
species
(ROS)
oxidative
damage.
Additionally,
agents
produced
by
pathogenic
bacteria
may
enter
body
via
two
primary
pathways:
directly
through
or
indirectly
cavity,
entering
bloodstream
reaching
brain.
This
infiltration
disrupts
cellular
homeostasis,
induces
neuroinflammation,
exacerbates
AD-related
pathology.
Addressing
these
mechanisms
personalized
treatment
strategies
target
underlying
causes
AD
could
play
critical
role
preventing
its
onset
progression.
American Journal of Critical Care,
Journal Year:
2025,
Volume and Issue:
34(3), P. 208 - 217
Published: May 1, 2025
Oral
bacteria
can
be
pathogenic
and
may
change
during
hospitalization,
potentially
increasing
risk
for
complications
older
adults,
including
residents
of
skilled
nursing
facilities
(SNFs).
To
compare
the
oral
microbiome
at
hospital
admission
by
prehospital
residence
(SNF
vs
home)
in
adults
not
receiving
mechanical
ventilation
to
assess
changes
their
hospitalization.
This
prospective,
observational
study
included
46
hospitalized
(≥65
years
old)
ventilation,
enrolled
within
72
hours
hospitalization
(15
admitted
from
SNF,
31
home).
health
was
assessed
with
Health
Assessment
Tool
baseline
days
3,
5,
7.
Genomic
DNA
extracted
unstimulated
saliva
specimens
profiling
using
16S
ribosomal
RNA
sequencing.
Taxonomic
composition,
relative
abundance,
α-diversity
(Shannon
Index),
β-diversity
(Bray-Curtis
dissimilarity)
bacterial
communities
were
determined.
Most
patients
female
(70%)
White
(74%)
or
Hispanic
(11%).
Mean
age
78.7
years.
More
SNFs
than
home
had
cognitive
impairment
(P
<
.001),
delirium
=
.01),
frailty
comorbidities
.04).
Patients
more
associated
disease,
lower
higher
.01).
In
28
completers,
altered
over
time
.001).
A
significant
interaction
found
between
groups
after
adjusting
covariates
Hospitalized
experience
microbial
disparities.
Introduction:
Dietary
factors
may
play
an
important
role
in
periodontal
health.
However,
current
evidence
from
observational
studies
remains
inconclusive.
Objective:
This
study
aimed
to
investigate
the
causal
relationships
between
dietary
exposures
and
disease
risks
using
Mendelian
randomization
analysis.
Methods:
Large-scale
genome-wide
association
summary
statistics
for
20
were
obtained
MRC-IEU
consortium.
Multivariable
univariable
2-sample
analyses
performed
assess
effects
of
each
exposure
on
6
outcomes,
including
gingivitis
periodontitis.
Results:
Genetically
predicted
higher
dried
fruit
intake
was
significantly
associated
with
reduced
acute
(odds
ratio
[OR]:
0.02;
95%
confidence
interval
[CI]:
0.00–0.42;
P
=
0.01)
bleeding
gums
(OR:
0.96;
CI:
0.93–0.99;
0.01).
Higher
fresh
water
showed
protective
against
chronic
0.18;
0.04–0.91;
0.04
OR:
0.15;
0.04–0.53;
0.00)
0.95;
0.92–0.981;
0.00
0.98;
0.96–0.99;
0.02).
Alcohol
frequency
processed
meat
risk
1.01;
1.00–1.02;
0.01
1.05;
1.01–1.08;
painful
1.00–1.01;
1.02;
1.01–1.03;
0.00).
Most
genetic
predisposition
specified
diseases
remained
statistically
significant
(P
<
0.05)
after
adjusting
dentures,
smoking,
type
2
diabetes
multivariable
models.
Conclusions:
The
findings
suggest
potential
other
problems,
while
alcohol
increase
disease.
Our
provides
preliminary
diet
health
could
inform
prevention
strategies
targeting
habits
improve
oral
Knowledge
Transfer
Statement:
suggests
that
protect
disease,
meats
risk,
informing
guidelines
Genes,
Journal Year:
2024,
Volume and Issue:
15(10), P. 1263 - 1263
Published: Sept. 27, 2024
:
A
growing
body
of
research
supports
the
role
microbial
communities
residing
in
digestive
system
host's
cognitive
functioning.
Most
these
studies
have
been
focused
on
gut
microbiome
and
its
association
with
clinical
phenotypes
middle-aged
older
adults.
There
is
an
insufficiency
population-based
exploring
normative
functioning
particularly
oral
microbiota.