REVIEWS ON ADVANCED MATERIALS SCIENCE,
Journal Year:
2022,
Volume and Issue:
61(1), P. 901 - 930
Published: Jan. 1, 2022
Abstract
Today,
the
growth
of
cosmetic
industry
and
dramatic
technological
advances
have
led
to
creation
functional
cosmetical
products
that
enhance
beauty
health.
Such
can
be
defined
as
topical
drugs
improve
health
functions
or
benefits.
Implementing
nanotechnology
advanced
engineering
in
these
has
enabled
innovative
product
formulations
solutions.
The
search
included
organic
molecules
used
cosmeceuticals
nanoparticles
(NPs)
field.
As
a
result,
this
document
analyses
use
inorganic
particles,
metals,
metal-oxides,
carbon-based
particles.
Additionally,
includes
lipid
solid
systems.
In
conclusion,
using
NPs
vehicles
active
substances
is
potential
tool
for
transporting
ingredients.
Finally,
review
while
presenting
progress
made
highlighting
hidden
challenges
associated
with
nanocosmeceuticals.
Cosmetics,
Journal Year:
2023,
Volume and Issue:
10(3), P. 84 - 84
Published: May 27, 2023
Vitiligo
is
an
acquired,
chronic
condition
characterised
by
depigmentation
of
the
epidermis
or
destruction/loss
melanin.
Skin
cells
(melanocytes)
are
responsible
for
producing
melanin,
substance
that
gives
pigmentation
to
skin.
This
review
aims
provide
a
comprehensive
overview
current
state
knowledge
about
vitiligo.
Although
there
no
specific
ethnic
group,
gender,
skin
type
more
prone
vitiligo
than
others,
it
can
affect
anyone.
The
most
commonly
prescribed
treatments
systemic
and
topical
phototherapy
immunomodulators
such
as
corticosteroids,
calcineurin
inhibitors,
vitamin
D
analogues,
in
addition
cosmetics
camouflage
improve
quality
life.
Even
though
typically
thought
cosmetic
disorder,
its
effects
on
physical
psychosocial
health
sufferers
cannot
be
ignored.
Molecular Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
The
high
content
of
vitamin
E,
including
tocopherols
and
tocotrienols
(TCF-TTE),
in
palm
oil
(Elaeis
guineensis)
has
made
it
a
promising
candidate
for
the
alternative
treatment
atopic
dermatitis
(AD).
However,
limited
solubility
TCF-TTE
restricted
its
therapeutic
efficacy.
In
this
study,
pluronic-based
micelles
(MCs)
encapsulating
oil-derived
were
formulated
with
dissolvable
microarray
patch-micelles
(DMP-MC)
using
carboxymethyl
cellulose
(CMC)
synthesized
from
empty
fruit
bunches
to
optimize
delivery
AD.
MC
was
prepared
direct
dissolution
method
Pluronic
F68
F127.
results
showed
that
increased
TCF-TTE,
which
further
confirmed
by
an
vitro
study
where
90.23
±
2.07%
TCF
4.56
1.36%
TTE
released
compared
unencapsulated
extract.
Furthermore,
CMC
biopolymers
integrated
into
DMP-MC
polyvinylpyrrolidone
(PVP)
exhibited
favorable
physical
properties,
such
as
mechanical
strength
penetration
ability.
also
better
platform
lower
permeation,
indicating
higher
retention
localized
effects
on
AD
skin
than
cream-MC.
Additionally,
dermatokinetic
profile
parameters
significant
improvement.
mean
residence
time
(MRT)
parameter
indicated
retained
longer
times
19.28
0.02
h
20.68
0.01
h.
Moreover,
vivo
revealed
could
relieve
symptoms
more
rapidly
oral
doses
cream-MC,
proved
be
efficient.
no
tissue
destruction
(granulation
fibrosis)
rats
treated
seventh
day.
Therefore,
successfully
developed
formula
formulation
CMC,
potentially
improve
AD's
Nanomedicine,
Journal Year:
2023,
Volume and Issue:
18(4), P. 391 - 411
Published: Feb. 1, 2023
Quercetin
is
a
well-known
plant
flavanol
that
exhibits
multiple
biological
activities,
including
antioxidant,
anti-inflammatory
and
anticancer
activities.
The
role
of
quercetin
in
wound
healing
has
been
widely
explored
by
range
researchers
different
models.
However,
the
physicochemical
properties,
such
as
solubility
permeability,
this
compound
are
low,
which
ultimately
limits
its
bioavailability
on
target
site.
To
overcome
these
limitations
for
successful
therapy,
scientists
have
developed
nanoformulations
provide
effective
therapeutic
potential.
In
review,
broad
mechanism
acute
chronic
wounds
covered.
A
compilation
recent
advances
horizon
via
incorporated
with
several
advanced
nanoformulations.
Antibiotics,
Journal Year:
2023,
Volume and Issue:
12(12), P. 1698 - 1698
Published: Dec. 4, 2023
The
skin
microbiome
is
crucial
in
maintaining
health,
and
its
disruption
associated
with
various
diseases.
Prebiotics
are
non-digestible
fibers
compounds
found
certain
foods
that
promote
the
activity
growth
of
beneficial
bacteria
gut
or
skin.
On
other
hand,
live
microorganisms,
known
as
probiotics,
benefit
sustaining
healthy
conditions
when
consumed
reasonable
quantities.
They
differ
from
postbiotics,
which
by-product
release
same
effects
their
parent
bacteria.
human
vital
it
comes
to
health
preventing
a
variety
dermatological
conditions.
This
review
explores
novel
strategies
use
microbiome-targeted
treatments
maintain
enhance
overall
while
managing
disorders.
It
important
understand
dynamic
relationship
between
these
microorganisms
diverse
microbial
communities
present
on
create
effective
for
using
probiotics
understanding
can
help
optimize
formulations
treatment
regimens
improved
outcomes
skincare,
particularly
developing
solutions
problems.
Pharmacological Reviews,
Journal Year:
2024,
Volume and Issue:
76(5), P. 689 - 790
Published: June 24, 2024
The
purpose
of
this
review
is
to
summarize
essential
biological,
pharmaceutical
and
clinical
aspects
in
the
field
topically
applied
medicines
that
may
help
scientists
when
trying
develop
new
topical
medicines.
After
a
brief
history
drug
delivery,
structure
function
skin,
routes
absorption
their
limitations
then
provided.
most
prevalent
diseases
current
treatment
approaches
are
detailed,
organization
which
reflects
key
disease
categories
autoimmune
inflammatory,
microbial
infections,
skin
cancers
genetic
diseases.
complexity
product
development
through
large
scale
manufacture
along
with
recommended
risk
mitigation
highlighted.
As
such
treatments
externally
patient
preferences
challenges
they
invoke
described
finally
future
delivery
discussed
emphasis
on
areas
more
likely
yield
significant
improvements
over
use
or
would
expand
range
treatable
by
route
administration.
Significance
Statement
This
its
associated
intricacies
formulation
should
be
helpful
making
judicious
decisions
about
improved
These
include
choices
active
ingredients,
formulations,
target
populations
regards
medicine
approaches.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(11), P. 2487 - 2487
Published: Nov. 17, 2022
Recently,
the
United
States
Food
and
Drug
Administration
published
a
series
of
product-specific
guidance
for
development
topical
drugs,
with
in
vitro
options
consisting
qualitative
sameness
(Q1)
quantitative
(Q2)
assessment
formulations,
physiochemical
structural
characterization
formulations
(Q3),
and,
potentially,
drug
release
permeation
tests.
In
these
tests,
semisolid
product’s
critical
quality
attributes
(CQAs),
such
as
rheological
properties,
thermodynamic
activity,
particle
size,
globule
rate/extent
release/permeation,
are
evaluated
to
ensure
desired
product
quality.
However,
alterations
CQAs
products
may
occur
under
‘in
use’
conditions
because
various
metamorphosis
events,
evaporation
that
leads
supersaturation
crystallization,
which
eventually
result
specific
failure
modes
products.
Under
conditions,
limited
amount
formulation
is
applied
skin,
where
physicochemical
characteristics
substantially
altered
from
primary
state
secondary
eventually,
tertiary
on
skin.
There
an
urgent
need
understand
behavior
conditions.
this
review,
we
attempt
cover
events
their
impact
(Q3
attributes),
viscosity,
release/permeation
Plants,
Journal Year:
2023,
Volume and Issue:
12(14), P. 2661 - 2661
Published: July 16, 2023
Transdermal
delivery
devices
and
wound
dressing
materials
are
constantly
improved
upgraded
with
the
aim
of
enhancing
their
beneficial
effects,
biocompatibility,
biodegradability,
cost
effectiveness.
Therefore,
researchers
in
field
have
shown
an
increasing
interest
using
natural
compounds
as
constituents
for
such
systems.
Plants,
important
source
so-called
“natural
products”
enormous
variety
structural
diversity
that
still
exceeds
capacity
present-day
sciences
to
define
or
even
discover
them,
been
part
medicine
since
ancient
times.
However,
benefits
just
at
beginning
being
fully
exploited
modern
dermal
transdermal
Thus,
plant-based
primary
compounds,
without
biological
activity,
contained
gums
mucilages,
traditionally
used
gelling
texturing
agents
food
industry,
now
explored
valuable
cost-effective
components
biomedical
field.
Their
non-toxicity
compensate
local
availability
compositional
variations.
Also,
secondary
metabolites,
classified
based
on
chemical
structure,
intensively
investigated
wide
pharmacological
toxicological
effects.
impact
is
highlighted
detail
through
most
recent
reported
studies.
Innovative
isolation
purification
techniques,
new
drug
systems,
advanced
evaluation
procedures
presented.
