Impact of action observation therapy on motor and cognitive outcomes in older adults with mild cognitive impairment: a randomized controlled study

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 21, 2025

Mild Cognitive Impairment (MCI) affects both cognitive and motor function, increasing the risk of immobility, falls, compromising independence. The aim this study is to determine whether implementing Action Observation Therapy (AOT) in a population with MCI would yield positive outcomes status, activities daily living (ADLs), upper limb (UL) functionality, gait balance, if these results differ based on observation modality employed. Thirty participants, aged 65 above MCI, were assigned three groups: therapist group (TOG), peer (POG), control (CG). intervention comprised physical exercises over 5 weeks, assessments before after. significant differences post-intervention improvement found between groups, excluding Box block test. No TOG POG any variable. Significant CG groups. AOT proved beneficial for individuals yielding when observing compared CG, domains: cognition, ADLs, balance.

Language: Английский

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Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 28, 2025

This review aimed to elucidate the mechanisms through which (i) physical activity (PA) enhances neuroplasticity and cognitive function in neurodegenerative disorders, (ii) identify specific PA interventions for improving rehabilitation programs. We conducted a literature search PubMed, Medline, Scopus, Web of Science, PsycINFO, covering publications from January 1990 August 2024. The strategy employed key terms related neuroplasticity, exercise, function, personalized activity. Inclusion criteria included original research on relationship between while exclusion eliminated studies focusing solely pharmacological interventions. identified multiple pathways may enhance including releasing neurotrophic factors, modulation neuroinflammation, reduction oxidative stress, enhancement synaptic connectivity neurogenesis. Aerobic exercise was found increase hippocampal volume by 1–2% improve executive scores 5–10% older adults. Resistance training enhanced control memory performance 12–18% elderly individuals. Mind–body exercises, such as yoga tai-chi, improved gray matter density memory-related brain regions 3–5% emotional regulation 15–20%. Dual-task attention processing speed 8–14% individuals with disorders. also discuss potential role AI-based AI preventing rehabilitating illnesses, highlighting innovative approaches patient outcomes. significantly disorders various mechanisms. resistance training, mind–body practices, dual-task exercises each offer unique benefits. Implementing these activities clinical settings can Future should focus creating tailored conditions, incorporating programs optimize rehabilitation.

Language: Английский

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Effects of Exercise Intervention for the Management of Delirium in Hospitalized Older Adults: A Randomized Clinical Trial

Journal of the American Medical Directors Association, Journal Year: 2024, Volume and Issue: 25(8), P. 104980 - 104980

Published: April 7, 2024

Language: Английский

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Microbiota–gut–brain axis: the mediator of exercise and brain health

Deleted Journal, Journal Year: 2024, Volume and Issue: 4

Published: Jan. 1, 2024

Abstract The brain controls the nerve system, allowing complex emotional and cognitive activities. microbiota–gut–brain axis is a bidirectional neural, hormonal, immune signaling pathway that could link gastrointestinal tract to brain. Over past few decades, gut microbiota has been demonstrated be an essential component of plays crucial role in regulating most functions various body organs. effects on occur through production neurotransmitters, hormones, metabolites, regulation host-produced or synthesis metabolites by themselves. This affects host's behavior, mood, attention state, brain's food reward system. Meanwhile, there intimate association between exercise. Exercise can change numerically qualitatively, which may partially responsible for widespread benefits regular physical activity human health. Functional magnetic resonance imaging (fMRI) non-invasive method show areas enabling delineation specific regions involved neurocognitive disorders. Through combining exercise tasks fMRI techniques, researchers observe higher functions. However, exercise's health via have little studied. article reviews highlights connections these three interactions, will help us further understand positive provide new strategies approaches prevention treatment diseases.

Language: Английский

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Management of cognitive frailty: A network meta‐analysis of randomized controlled trials

International Journal of Geriatric Psychiatry, Journal Year: 2023, Volume and Issue: 38(9)

Published: Sept. 1, 2023

We aimed to compare the effectiveness of interventions in cognitive function and frailty status rank these interventions.Data Sources-We searched PubMed, Embase, CINAHL, PsycINFO, Web Science, Cochrane Library, Central Register Controlled Trials (CENTRAL), CNKI, Wanfang, VIP Google scholar. Data synthesis-The risk bias was assessed using assessment tool. Statistical heterogeneity Chi-square test quantified by I2 . The results were pooled standardized mean difference (SMD). probability for each intervention calculated surface under cumulative ranking curve (SUCRA). Additionally, quality evidence evaluated GRADE approach.A total 10 randomized controlled trials (RCTs) involving 1110 patients included our analysis. network map comprised 9 RCTs with 1347 participants, examining eight different interventions. Nutritional support (SUCRA = 99.9%, SMD 3.02, 95% CI: 2.53, 3.51) may be most effective improve function. (including 1017 participants interventions) suggested that multicomponent exercises 96.4%, -5.10, -5.96, -4.23) tended have a greater effect.Community-based shown significant benefits improving older adults, moderate certainty. For hospitalized Cognitive (CF), current suggests nutritional yields improvement. aerobic exercise dual-task training proven managing CF. Further studies are needed validate preliminary findings exploring more accessible physical prevent CF aging.

Language: Английский

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The effectiveness of exercise interventions targeting sleep in older adults with cognitive impairment or Alzheimer's disease and related dementias (AD/ADRD): A systematic review and meta‐analysis

Journal of Sleep Research, Journal Year: 2024, Volume and Issue: 33(6)

Published: March 10, 2024

Summary Sleep loss is associated with reduced health and quality of life, increased risk Alzheimer's disease related dementias. Up to 66% persons dementias experience poor sleep, which can predict or accelerate the progression cognitive decline. Exercise a widely accessible intervention for sleep that protect against functional No previous systematic reviews have investigated effectiveness exercise in older adults mild impairment We systematically reviewed controlled interventional studies targeting subjectively objectively (polysomnography/actigraphy) assessed conducted searches PubMed, Embase, Scopus Cochrane‐Library ( n = 6745). Nineteen randomised one non‐randomised trials were included, representing experiences 3278 Ten had low‐risk, nine moderate‐risk, high‐risk bias. Six subjective eight objective outcomes meta‐analysed (random‐effects model). found moderate‐ high‐quality evidence beneficial effects on self‐reported objectively‐measured However, no examined key potential moderators these effects, such as sex, napping medication use. Our results important implications clinical practice. may be most modifiable factors range conditions, including decline Given our findings, clinicians consider adding an effective adjuvant strategy improving

Language: Английский

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Does resistance training in older adults lead to structural brain changes associated with a lower risk of Alzheimer’s dementia? A narrative review

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 98, P. 102356 - 102356

Published: May 31, 2024

Language: Английский

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Does Therapeutic Exercise Support Improvement in Cognitive Function and Instrumental Activities of Daily Living in Patients with Mild Alzheimer’s Disease? A Randomized Controlled Trial

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(7), P. 1112 - 1112

Published: July 22, 2023

This randomized controlled trial aims to investigate the effect of 12 weeks therapeutic exercise on cognitive function and daily activities in patients with mild Alzheimer's disease (AD). A total 171 AD from Amarousion Day Care Center Alzheimer Society Athens General Hospital "G. Gennimatas" were randomly divided into three groups. Group (aerobic resistance exercise, n = 57), group B (resistance C (control group, 57). followed a weekly program consisting 5 days 30 min walking 3 exercises for about 45 min. only program, same as A. did not participate any program. After intervention, was assessed Cognitive Examination-Revised (ACE-R), Trail Making Test A-B (TMT A-B), Digit Span Forward Backward (DST F-B) instrumental living scale (IADLs). significant intervention observed all outcome measures (global living). ANCOVA Bonferroni corrected post hoc tests revealed that aerobic improved compared control measurement scales. The also showed an improvement group. No effects found between measures.

Language: Английский

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Systematic review and meta-analysis of randomized controlled trials on the effects of exercise interventions on amyloid beta levels in humans

Experimental Brain Research, Journal Year: 2024, Volume and Issue: 242(5), P. 1011 - 1024

Published: March 29, 2024

Language: Английский

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Physical exercise on cortical brain activity in patients with mild cognitive impairment: A meta-analysis

Medicine, Journal Year: 2024, Volume and Issue: 103(35), P. e39452 - e39452

Published: Aug. 30, 2024

Physical exercise is recognized as a potential strategy to mitigate the cognitive decline associated with mild impairment (MCI). This systematic review aims examine specific effects of physical on cortical brain activity in patients MCI, an area that has not been thoroughly explored.

Language: Английский

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