Cell consciousness: a dissenting opinion

EMBO Reports, Journal Year: 2024, Volume and Issue: 25(5), P. 2162 - 2167

Published: March 28, 2024

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In search for consciousness in animals: Using working memory and voluntary attention as behavioral indicators

Neuroscience & Biobehavioral Reviews, Journal Year: 2022, Volume and Issue: 142, P. 104865 - 104865

Published: Sept. 9, 2022

Language: Английский

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Growing Confidence and Remaining Uncertainty About Animal Consciousness

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: July 3, 2024

While the study of consciousness has had a controversial history and, until recently, pessimistic prognosis, recent views within neuroscientific community suggest that maturing if incomplete scientific understanding is close at hand. The purpose this essay to specify major points on which in my opinion there widespread though not universal agreement, as proposed benchmarks for current state research across phylogenetic spectrum. Most published definitions boil down focus it process arising nervous system engaged with body and its environment, giving rise subjective (personal) experience. A broad consensus phenomenology sees consisting minimum (1) awareness_ _and focused attention, (2) unity perception, (3) qualitative variations content, (4) mental causation, (5) sense self. There also agreement substrate requires sizeable, complex systems organized into several hierarchical levels processing. Further insight gained by reconstructing evolution phenomenological experience ― most likely from multiple origins, hosted diversity brain architectures, diverging markedly different forms animal kingdom. However, three mysteries about remain unresolved are neurological correlates consciousness, apparent gap between mechanism, monitors activity admitted consciousness.

Language: Английский

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Cognitive Control and Consciousness in Open Biological Systems

Biosystems, Journal Year: 2025, Volume and Issue: unknown, P. 105457 - 105457

Published: April 1, 2025

Thermodynamically open biological systems not only sustain a life-supporting mutual relationship with their environment by exchanging matter and energy but constantly seek information to navigate probabilistic changes in surroundings. This work argues that cognition conscious thought should be viewed isolation rather as parts of an integral control identify act upon meaningful, semantic viability. Under this framework, the development key cognitive capacities centralized nervous resulting behavior are categorized into distinct Markov decision processes: decision-making partially observable sensory exteroceptive interoceptive information, learning memory, symbolic communication. It is proposed state arises from mechanism for speech production resembling actuator engineered systems. Also known phonological loop, feedback motor cortex provides third type flowing cortex. The continuous, dissipative loop updates fleeting working memory humans advanced layer through sense self, agency perception flow time. These define degrees fitness evolution information-powered organisms.

Language: Английский

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Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories

Journal of Neuroscience, Journal Year: 2024, Volume and Issue: 44(34), P. e0468242024 - e0468242024

Published: July 11, 2024

The medial prefrontal cortex (mPFC) is a major contributor to relapse cocaine in humans and reinstatement rodent models of use disorder. output from the mPFC potently modulated by parvalbumin (PV)-containing fast-spiking interneurons, majority which are surrounded perineuronal nets. We previously showed that treatment with chondroitinase ABC (ABC) reduced consolidation reconsolidation conditioned place preference memory. However, self-administration memories more difficult disrupt. Here we report male rats attenuated blocked was when were given novel, but not familiar, type retrieval session. Furthermore, prior to, after, memory reconsolidation. This same did alter sucrose memory, indicating specificity for cocaine-induced In naive rats, altered levels PV intensity cell firing properties. vivo recordings dorsal hippocampus (dHIP) during novel session revealed prevented reward-associated increases high-frequency oscillations synchrony these between dHIP mPFC. Together, this first study show disrupts original combined elicits coupling after may serve as fundamental signature how disrupt reduce relapse.

Language: Английский

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Machine learning approach for early onset dementia neurobiomarker using EEG network topology features

Frontiers in Human Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: June 16, 2023

Modern neurotechnology research employing state-of-the-art machine learning algorithms within the so-called "AI for social good" domain contributes to improving well-being of individuals with a disability. Using digital health technologies, home-based self-diagnostics, or cognitive decline managing approaches neuro-biomarker feedback may be helpful older adults remain independent and improve their wellbeing. We report results on early-onset dementia neuro-biomarkers scrutinize cognitive-behavioral intervention management non-pharmacological therapies.We present an empirical task in EEG-based passive brain-computer interface application framework assess working memory forecasting mild impairment. The EEG responses are analyzed network neuroscience technique applied time series evaluation confirm initial hypothesis possible ML modeling impairment prediction.We findings from pilot study group Poland prediction. utilize two emotional tasks by analyzing facial emotions reproduced short videos. A reminiscent interior image oddball is also employed validate proposed methodology further.The three experimental current showcase critical utilization artificial intelligence prognosis adults.

Language: Английский

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Conscious Experience of Stimulus Presence and Absence Is Actively Encoded by Neurons in the Crow Brain

Journal of Cognitive Neuroscience, Journal Year: 2024, Volume and Issue: 36(3), P. 508 - 521

Published: Jan. 1, 2024

The emergence of consciousness from brain activity constitutes one the great riddles in biology. It is commonly assumed that only conscious perception presence a stimulus elicits neuronal activation to signify "neural correlate consciousness," whereas subjective experience absence associated with resting state. Here, we demonstrate two states "stimulus present" and absent" are represented by specialized neuron populations crows, corvid birds. We recorded single-neuron nidopallium caudolaterale crows trained report or images presented near visual threshold. Because task design, tracking "present" versus "absent" percept was dissociated involved planning motor response. Distinct signaled percepts increases activation. response selectivity these similar strength time course. This suggests balanced code for "presence" "absence" experiences, which might be beneficial when both need maintained active service goal-directed behavior.

Language: Английский

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Growing Confidence and Remaining Uncertainty About Animal Consciousness

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 17, 2024

While the study of consciousness has had a controversial history and, until recently, pessimistic prognosis, recent views within neuroscientific community suggest that maturing if incomplete scientific understanding is close at hand. Most published definitions boil down to focus on it as process arising in nervous system engaged with body and its environment, giving rise subjective (personal) experience. A broad consensus phenomenology sees consisting minimum (1) awarenessand focused attention, (2) unity perception, (3) qualitative variations content, (4) mental causation, (5) sense self. There also agreement substrate requires sizeable, complex systems organized into several hierarchical levels processing. Further insight gained by reconstructing evolution phenomenological experience ― most likely from multiple origins, hosted diversity brain architectures, diverging markedly different forms across animal kingdom. The three major mysteries remain about are neurological correlates consciousness, apparent gap between mechanism, agent monitors activity admitted consciousness.

Language: Английский

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Growing Confidence and Remaining Uncertainty About Animal Consciousness

Qeios, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 26, 2024

While the study of consciousness has had a controversial history and, until recently, pessimistic prognosis, recent views within neuroscientific community suggest that maturing if incomplete scientific understanding is close at hand. The purpose this essay to specify major points on which in my opinion there widespread though not universal agreement, as proposed benchmarks for current state research across phylogenetic spectrum. Most published definitions boil down focus it process arising nervous system engaged with body and its environment, giving rise subjective (personal) experience. A broad consensus phenomenology sees consisting minimum (1) awarenessand focused attention, (2) unity perception, (3) qualitative variations content, (4) mental causation, (5) sense self. There also agreement substrate requires sizeable, complex systems organized into several hierarchical levels processing. Further insight gained by reconstructing evolution phenomenological experience ― most likely from multiple origins, hosted diversity brain architectures, diverging markedly different forms animal kingdom. However, three mysteries about remain unresolved are neurological correlates consciousness, apparent gap between mechanism, monitors activity admitted consciousness.

Language: Английский

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Neuro-functional modeling of near-death experiences in contexts of altered states of consciousness

Frontiers in Psychology, Journal Year: 2023, Volume and Issue: 13

Published: Jan. 18, 2023

Near-death experiences (NDEs) including out-of-body (OBEs) have been fascinating phenomena of perception both for affected persons and communities in science medicine. Modern progress the recording changing brain functions during time between clinical death opened perspective to address understand generation NDEs states altered consciousness. Changes consciousness can experimentally be induced well-controlled or laboratory settings. Reports having experienced changes inform about similarity with those from original NDEs. Thus, we collected neuro-functional models OBEs experimental backgrounds drug consumption, epilepsy, stimulation, ischemic stress, included so far largely unappreciated data fighter pilot tests under gravitational stress generating cephalic nervous system ischemia. Since found a large overlap NDE themes topics reports models, state that, collectively, offer scientifically appropriate causal explanations occurrence The OBEs, one themes, localized temporo-parietal junction (TPJ) brain, multimodal association area. evaluated literature suggests that may emerge as hallucination-like (ASCs).

Language: Английский

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