NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview

Gels, Journal Year: 2024, Volume and Issue: 10(2), P. 107 - 107

Published: Jan. 28, 2024

Natural deep eutectic solvents (NaDES) represent a new generation of green, non-flammable solvents, useful as an efficient alternative to the well-known ionic liquids. They can be easily prepared and exhibit unexpected solubilizing power for lipophilic molecules, although those hydrophilic nature are mostly used. For their unique properties, they recommend different cosmetic pharmaceutical applications, ranging from sustainable extraction, obtaining ready-to-use ingredients, development biocompatible drug delivery responsive systems. In biomedical field, NaDES used biopolymer modifiers, acting compounds also known “therapeutic systems”, being able solubilize stabilize chemical galenical formulations. The aim this review is give overview current knowledge regarding natural specifically applied in fields. work could help disclose opportunities challenges implementation not only green but potential pathways deliver bioactive ingredients innovative

Language: Английский

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Trends and perspectives on the ultrasound-assisted extraction of bioactive compounds using natural deep eutectic solvents

Current Opinion in Chemical Engineering, Journal Year: 2025, Volume and Issue: 47, P. 101088 - 101088

Published: Jan. 10, 2025

Language: Английский

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Comparison, optimization and antioxidant activity of ultrasound-assisted natural deep eutectic solvents extraction and traditional method: A greener route for extraction of flavonoid from Moringa oleifera Lam. leaves

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 109, P. 107003 - 107003

Published: July 27, 2024

To develop an environmentally sustainable and efficient extraction method for flavonoids from Moringa oleifera Lam. (M. oleifera) leaves, natural deep eutectic solvents (NADES) with ultrasound-assisted was utilized in this study. After optimization of parameters NADES, including ultrasonic power, time, liquid–solid ratio, the yield NADES (UAN) composed betaine urea (Bet-Urea) reached 54.69 ± 0.19 mg RE/g DW, which made a 1.7-fold increase compared to traditional solvent (UATS). UPLC-Q Exactive/MS analysis revealed that M. leaves (MOLF) mainly Quercetin 3-β-D-glucoside, Rutin, Kaempferol-3-O-glucoside, Vitexin Quercetin. Furthermore, COSMO-RS model employed verify optimal compatibility solubility activity coefficient between Bet-Urea five primary MOLF. In vitro antioxidant assays verified MOLF extracted by UAN exhibited superior UATS. Overall, devised process not only augmented but also effectively preserved bioactive compounds, thus promoting utilization green food industry.

Language: Английский

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Natural deep eutectic solvents (NaDES): translating cell biology to processing

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(22), P. 9045 - 9062

Published: Jan. 1, 2023

This review examines the possible functional roles of liquid natural deep eutectic solvents (NaDES) in plants and translating it to laboratory.

Language: Английский

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Optimization of an ultrasound‐assisted extraction method to obtain gallic acid‐rich extracts from mango seed kernels

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(6), P. 4038 - 4048

Published: April 12, 2024

Abstract Gallic acid is a widely recognized bioactive compound that falls under the category of secondary polyphenolic metabolites and fairly found in mango fruit waste, specifically seed kernel (MSK). This study aimed to adopt green extraction approach extract this valuable via ultrasound‐assisted (UAE) without using organic solvents but only water obtain hazard‐free extracts, cost can be minimal. pH (2–8), solvent ratio (20–60 mL/g), temperature (30–60°C) time (30–60 min) were independent variables used for optimization. Single‐factor experiments working ranges selected carried out. A central composite design response surface methodology was determine optimum condition maximum yield gallic from MSK. The optimized conditions 3.9 pH, 36.25 mL/g ratio, 39.4°C 21.3 min. As result, 5.76 ± 0.41 mg/g, which comparably equal and/or better than other systems. results showed could efficiently extracted UAE these optimal conditions. It safer systems involving hazardous feasibly its nutraceutical therapeutic applications.

Language: Английский

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Controlled cross-linking and tailored affinity characteristic of Janus silica nanosheets hydrogel via pickering high internal phase emulsions (HIPEs) system for high-accuracy separation of naringin

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 131355 - 131355

Published: Jan. 1, 2025

Language: Английский

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A customizable CO2-Responsive supramolecular solvent for the simultaneous extraction of Multi-Polar phytochemicals from plants

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112959 - 112959

Published: Feb. 1, 2025

Language: Английский

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Research progress on extraction of flavonoids with deep eutectic solvents from natural products

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 127356 - 127356

Published: March 1, 2025

Language: Английский

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A Review of Classical and Rising Approaches the Extraction and Utilization of Marine Collagen

BioTech, Journal Year: 2025, Volume and Issue: 14(2), P. 26 - 26

Published: April 3, 2025

This comprehensive review explores the extraction and utilization of marine collagen, a sustainable alternative to traditional mammalian sources. The covers conventional methods like acid pepsin solubilization, highlighting their limitations contributing search for improved efficiency sustainability. It also delves into innovative technologies, such as ultrasound-assisted extraction, deep eutectic solvents, supercritical carbon dioxide, showing potential revolutionize field. significance collagen hydrolysis in generating bioactive peptides with diverse functionalities is discussed, emphasizing applications various sectors. By providing an analysis its implications, this presents perspective leveraging valuable bioresource, promoting circular economy, satisfying increasing demand high-quality industries.

Language: Английский

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Novel Insights Into Naringenin: A Multifaceted Exploration of Production, Synthesis, Health Effects, Nanodelivery Systems, and Molecular Simulation

Molecular Nutrition & Food Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 14, 2025

ABSTRACT Naringenin, a flavonoid widely present in citrus fruits, has garnered considerable attention due to its diverse biological activities and health‐promoting benefits. As research on naringenin advances, the application scope of significantly expanded. This paper provides systematic overview production synthesis methods naringenin, focusing especially green extraction techniques strategies for constructing microbial metabolic engineering. Naringenin not only achieves including antioxidant, antiinflammatory, glucolipid metabolism regulation through multiple mechanisms but also modulates balance gut microbiota, thereby mediating synergistic health effects via host–microbial axis. Given low oral bioavailability various nanodelivery systems have been developed improve bioavailability. Meanwhile, molecular simulation elucidate binding conformation characteristics with receptors at level, providing novel insights into action. In conclusion, this review seeks offer theoretical basis future directions further naringenin.

Language: Английский

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