International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(3), P. 1806 - 1806
Published: Feb. 2, 2024
The
gut
microbiota
of
healthy
breastfed
infants
is
often
dominated
by
bifidobacteria.
In
an
effort
to
mimic
the
infants,
modern
formulas
are
fortified
with
bioactive
and
bifidogenic
ingredients.
These
ingredients
promote
optimal
health
development
as
well
infant
microbiota.
Here,
we
used
INFOGEST
in
vitro
batch
fermentation
model
investigate
health-promoting
effects
a
commercial
formula
supplemented
blend
containing
docosahexaenoic
acid
(DHA)
(20
mg/100
kcal),
polydextrose
galactooligosaccharides
(PDX/GOS)
(4
g/L,
1:1
ratio),
milk
fat
globule
membrane
(MFGM)
(5
g/L),
lactoferrin
(0.6
Bifidobacterium
animalis
subsp.
lactis,
BB-12
(BB-12)
(106
CFU/g).
Using
fecal
inoculates
from
three
assessed
changes,
effect,
short-chain
fatty
(SCFA)
production
test
compared
those
data
obtained
unsupplemented
base
breast
control.
Our
results
show
that
even
after
digestion
formula,
can
still
maintain
its
bioactivity
modulate
infants'
composition,
faster
bifidobacterial
growth,
stimulate
SCFAs.
Thus,
it
may
be
concluded
promotes
SCFA
profile
something
similar,
but
not
identical
infants.
Discover Food,
Journal Year:
2024,
Volume and Issue:
4(1)
Published: June 13, 2024
Abstract
The
water
buffalo
breed
known
as
the
Murrah
(
Bubalus
bubalis
)
is
primarily
raised
for
its
milk.
It
preserved
in
Indian
states
of
Haryana
and
Punjab,
namely
districts
Bhiwani,
Agra,
Hisar,
Rohtak,
Jind,
Jhajhar,
Fatehabad,
Gurgaon,
Delhi
capital
city.
fat
from
milk
also
contains
ketoglycerides.
While
β-lactoglobulin,
which
branched
chain
essential
amino
acids
well
a
retinol-binding
protein
that
may
modulate
lymphatic
processes,
absent
human
milk,
has
somewhat
more
this
than
cow’s
primary
source
whey
protein.
ability
to
create
antimicrobial
peptides
work
against
gram-positive
bacteria
are
released
by
proteolytic
enzymes
during
trypsin-catalyzed
digestion.
International
dairy
product
production
increasingly
shifting
domestic
substitute
source.
Buffalo
high
amount
calcium,
mineral
necessary
development
bones.
Moreover,
it
casein-derived
peptides,
promote
bone
health
reduce
likelihood
osteoporosis,
disorder
characterized
weakening
bones
an
increased
risk
fractures.
Customers
love
because
excellent
nutritional
value.
be
eaten
raw
or
used
manufacture
premium
products
like
cheese,
yogurt,
ice
cream,
other
traditional
products.
Cell Metabolism,
Journal Year:
2024,
Volume and Issue:
36(8), P. 1882 - 1897.e7
Published: June 3, 2024
Comprehensive
whole-body
models
(WBMs)
accounting
for
organ-specific
dynamics
have
been
developed
to
simulate
adult
metabolism,
but
such
do
not
exist
infants.
Here,
we
present
a
resource
of
360
organ-resolved,
sex-specific
newborn
and
infant
metabolism
(infant-WBMs)
spanning
the
first
180
days
life.
These
infant-WBMs
were
parameterized
represent
distinct
metabolic
characteristics
newborns
infants,
including
nutrition,
energy
requirements,
thermoregulation.
We
demonstrate
that
predicted
growth
was
consistent
with
recommendation
by
World
Health
Organization.
assessed
infant-WBMs'
reliability
capabilities
personalization
simulating
10,000
based
on
their
blood
metabolome
birth
weight.
Furthermore,
accurately
changes
in
known
biomarkers
over
time
responses
treatment
strategies
inherited
diseases.
The
infant-WBM
holds
promise
personalized
medicine,
as
could
be
step
digital
twins
metabolism.
Foods,
Journal Year:
2025,
Volume and Issue:
14(3), P. 512 - 512
Published: Feb. 5, 2025
The
rapid
development
of
nanotechnology
provides
new
approaches
to
manufacturing
food-related
nanoparticles
in
various
food
industries,
including
formulation,
functional
foods,
packaging,
and
quality
control.
Once
ingested,
will
immediately
adsorb
proteins
the
biological
fluids,
forming
a
corona
around
them.
Protein
coronas
alter
properties
nanoparticles,
their
toxicity,
cellular
uptake,
targeting
characteristics,
by
altering
aggregation
state.
In
addition,
conformation
function
enzymes
are
also
influenced
formation
protein
coronas,
affecting
digestion
products.
Since
inevitable
application
industries
subsequent
digestion,
comprehensive
understanding
is
essential.
This
systematic
review
introduces
explains
with
interactions
between
nanoparticles.
Furthermore,
potential
origin
that
migrate
from
packaging
materials
fates
gastrointestinal
tract
has
been
reviewed.
Finally,
this
explores
possible
effects
on
bioactive
compounds,
probiotics
prebiotics.
Understanding
mechanisms
crucial,
as
it
enables
design
tailored
delivery
systems
optimize
bioavailability
compounds.
GSC Advanced Research and Reviews,
Journal Year:
2024,
Volume and Issue:
19(1), P. 004 - 015
Published: April 7, 2024
This
review
examines
the
landscape
of
baby
food
product
management,
highlighting
diverse
nutritional
needs,
innovative
practices,
and
regulatory
challenges
encountered
by
companies
operating
in
Nigeria
United
States
(US).
As
essential
stakeholders
infant
health,
manufacturers
must
navigate
a
complex
terrain
shaped
cultural
preferences,
economic
factors,
governmental
regulations
to
meet
requirements
infants
young
children.
In
both
US,
needs
are
paramount,
with
an
increasing
emphasis
on
providing
balanced
diets
that
support
optimal
growth
development.
However,
specific
dietary
may
vary
between
regions
due
regional
agricultural
availability,
socio-economic
factors.
Understanding
catering
these
nuanced
is
critical
for
establish
trust
credibility
among
consumers.
Moreover,
innovations
management
play
crucial
role
addressing
evolving
consumer
demands
preferences.
From
organic
natural
ingredients
convenient
packaging
solutions,
continuously
striving
enhance
quality
convenience
products.
These
not
only
reflect
shifting
trends
but
also
serve
as
competitive
differentiator
crowded
market.
Nevertheless,
navigating
presents
significant
US.
Regulatory
frameworks
governing
safety,
labeling
requirements,
advertising
standards
subject
frequent
updates
modifications,
requiring
maintain
agility
compliance.
Additionally,
perceptions
surrounding
feeding
practices
influence
approaches,
further
complicating
market
entry
expansion
strategies.
underscores
importance
understanding
unique
embracing
products
By
adopting
comprehensive
approach
considers
market-specific
factors
global
best
can
effectively
markets
contribute
health
well-being
Gut Microbes,
Journal Year:
2024,
Volume and Issue:
16(1)
Published: Aug. 19, 2024
Here,
we
explored
the
vast
potential
of
microbiome-based
interventions
in
preventing
and
managing
non-communicable
diseases
including
obesity,
diabetes,
allergies,
celiac
disease,
inflammatory
bowel
diseases,
malnutrition,
cardiovascular
across
different
life
stages.
We
discuss
intricate
relationship
between
microbiome
emphasizing
on
"window
opportunity"
for
microbe–host
interactions
during
first
years
after
birth.
Specific
biotics
also
live
biotherapeutics
fecal
microbiota
transplantation
emerge
as
pivotal
tools
precision
medicine,
acknowledging
"one
size
doesn't'
fit
all"
aspect.
Challenges
implementation
underscore
need
advanced
technologies,
scientific
transparency,
public
engagement.
Future
perspectives
advocate
understanding
maternal−neonatal
microbiome,
exploring
maternal
exposome
delving
into
human
milk's
role
establishment
restoration
infant
its
influence
over
health
disease.
An
integrated
approach,
employing
multi-omics
accounting
inter-individual
variance
composition
function
appears
central
to
unleash
full
early-life
revolutionizing
healthcare.
Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: Sept. 22, 2023
In
order
to
achieve
rapid
detection
of
galactooligosaccharides
(GOS),
fructooligosaccharides
(FOS),
calcium
(Ca),
and
vitamin
C
(Vc),
four
micronutrient
components
in
infant
formula
milk
powder,
this
study
employed
methods,
namely
Standard
Normal
Variate
(SNV),
Multiplicative
Scatter
Correction
(MSC),
Normalization
(Nor),
Savitzky–Golay
Smoothing
(SG),
preprocess
the
acquired
original
spectra
powder.
Then,
Competitive
Adaptive
Reweighted
Sampling
(CARS)
algorithm
Random
Frog
(RF)
were
used
extract
representative
characteristic
wavelengths.
Furthermore,
Partial
Least
Squares
Regression
(PLSR)
Support
Vector
(SVR)
models
established
predict
contents
GOS,
FOS,
Ca,
Vc
The
results
indicated
that
after
SNV
preprocessing,
GOS
FOS
could
effectively
feature
wavelengths
using
CARS
algorithm,
leading
favorable
predictive
through
CARS-SVR
model.
Similarly,
MSC
Ca
efficiently
resulting
optimal
outcomes
via
This
provides
insights
for
realization
online
nutritional
component
optimization
control
production
process
formula.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(9), P. 2044 - 2044
Published: April 29, 2024
The
quality
of
fat
in
infant
milk
is
determined
by
the
fatty
acid
profile
and
selected
indices
describing
nutritional
value.
aim
this
study
was
to
analyze
lipid
formulas
compare
these
data
with
breast
milk.
material
included
seven
types
cow’s
milk-based
follow-on
samples
mature
determination
acids
performed
using
gas
chromatography
(GC)
technique.
Lipid
were
calculated
based
on
relevant
equations.
Infant
contained
more
medium-chain
(MCFAs)
oleic
acid.
Moreover,
they
than
30%
linoleic
twice
as
much
α-linolenic
docosahexaenoic
In
contrast,
significant
amounts
trans
(TFAs)
noted
milk,
while
trace
amounts.
characterized
a
lower
AI
(Index
Atherogenicity)
(0.49–0.98)
TI
Thrombogenicity)
(0.48–0.60)
higher
H/H
(hypocholesterolemic/hypercholesterolemic)
ratio
(1.93–2.30)
compared
(1.47,
1.60,
1.21,
respectively).
composition
depended
type
added
at
production
stage
differed
significantly
from
particularly
terms
polyunsaturated
indices.
