The Combination of Chitosan-Based Biomaterial and Cellular Therapy for Successful Treatment of Diabetic Foot—Pilot Study

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(15), P. 8388 - 8388

Published: Aug. 1, 2024

Diabetic foot ulceration is one of the most common complications in patients treated for diabetes mellitus. The presented pilot study describes successful treatment diabetic heel with ongoing osteomyelitis a 39-year-old patient after using combination modified chitosan-based biomaterial autologous mesenchymal stem cells isolated from bone marrow and dermal fibroblasts. population fulfilled all attributes given by International Society Stem Cell Research, such as fibroblast-like morphology, high expression positive surface markers (CD29: 99.1 ± 0.4%; CD44: 99.8 0.2% CD90: 98.0 0.6%) ability to undergo multilineage differentiation. Likewise, fibroblasts showed positivity widely accepted collagen I, III vimentin, which was confirmed immunocytochemical staining. Moreover, we were able describe newly formed blood vessels shown angio CT almost complete closure skin defect 8 months treatment.

Language: Английский

---

Empirical Use, Phytochemical, and Pharmacological Effects in Wound Healing Activities of Compounds in Diospyros Leaves: A Review of Traditional Medicine for Potential New Plant-Derived Drugs

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 337, P. 118966 - 118966

Published: Oct. 18, 2024

Language: Английский

---

Bioengineering the Heart: Harnessing Biomaterials for Innovative Cardiovascular Interventions

Journal of Cardiovascular Intervention, Journal Year: 2024, Volume and Issue: 3(3), P. 136 - 136

Published: Jan. 1, 2024

Language: Английский

---

FTY720P-treated macrophages in PEG-4MAL hydrogels promote oral wound healing

Cytotherapy, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

---