Chronic Pain and Joint Hypermobility: A Brief Diagnostic Review for Clinicians and the Potential Application of Infrared Thermography in Screening Hypermobile Inflamed Joints DOI Creative Commons
João Alberto de Souza Ribeiro, Guilherme Gomes, Alexandre Aldred

et al.

The Yale Journal of Biology and Medicine, Journal Year: 2024, Volume and Issue: 97(2), P. 225 - 238

Published: June 28, 2024

Joint hypermobility syndromes, particularly chronic pain associated with this condition, including Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD), present diagnostic challenges due to their multifactorial origins remain poorly understood from biomechanical genomic-molecular perspectives. Recent guidelines have differentiated hEDS, HSD, benign joint hypermobility, providing a more objective framework. However, incorrect diagnoses underdiagnoses persist, leading prolonged journeys for affected individuals. Musculoskeletal manifestations, pain, dysautonomia, gastrointestinal symptoms illustrate the impact of these conditions, affecting both physical emotional well-being Infrared thermography (IRT) emerges as promising tool assessment, especially in detecting inflammatory processes. Thermal distribution patterns offer valuable insights into dysfunctions, although direct correlation between inflammation remains challenging. The prevalence neuropathies among hypermobile individuals accentuates discordance perception thermographic findings, further complicating diagnosis management. Despite its potential, clinical integration IRT faces challenges, conflicting evidence hindering adoption. studies demonstrate temperature disparities healthy diseased joints, under dynamic thermography, suggesting potential utility practice. Future research focused on refining criteria elucidating underlying mechanisms syndromes will be essential improve accuracy enhance patient care complex multidimensional context.

Language: Английский

Wound management materials and technologies from bench to bedside and beyond DOI
Canran Wang, Ehsan Shirzaei Sani, Chia-Ding Shih

et al.

Nature Reviews Materials, Journal Year: 2024, Volume and Issue: 9(8), P. 550 - 566

Published: June 17, 2024

Language: Английский

Citations

83
Sensors and Devices Guided by AI for Personalized Pain Medicine DOI Creative Commons
Yantao Xing, Kaiyuan Yang,

Albert Lu

et al.

Cyborg and Bionic Systems, Journal Year: 2024, Volume and Issue: 5

Published: Jan. 1, 2024

Personalized pain medicine aims to tailor treatment strategies for the specific needs and characteristics of an individual patient, holding potential improving outcomes, reducing side effects, enhancing patient satisfaction. Despite existing markers treatments, challenges remain in understanding, detecting, treating complex conditions. Here, we review recent engineering efforts developing various sensors devices addressing personalized pain. We summarize basics pathology introduce monitoring, assessment, relief. also discuss advancements taking advantage rapidly medical artificial intelligence (AI), such as AI-based analgesia devices, wearable sensors, healthcare systems. believe that these innovative technologies may lead more precise responsive medicine, greatly improved quality life, increased efficiency systems, incidence addiction substance use disorders.

Language: Английский

Citations

18
Flexible and temperature-responsive hydrogel dressing for real-time and remote wound healing monitoring DOI

Ji Jiang,

Jie Ding, Xiaoyang Wu

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 11(22), P. 4934 - 4945

Published: Jan. 1, 2023

A flexible hydrogel based on PAA- g -PNIPAM/PAM-AgNWs was established as a conductive and temperature-responsive matrix. By integrating wireless Bluetooth module, real-time remote monitoring of wound temperature is realized for smart management.

Language: Английский

Citations

39
Application of Infrared Thermography for Predicting Pressure Injury Healing: A Prospective Study DOI Creative Commons

Lu‐Lu Lin,

Dongwei Zhuang,

Hailei Guo

et al.

Journal of Tissue Viability, Journal Year: 2025, Volume and Issue: 34(2), P. 100857 - 100857

Published: Jan. 9, 2025

An accurate assessment of pressure injury healing is crucial for the timely implementation nursing intervention. This study aimed to investigate accuracy infrared thermography-based wound temperature measurement in predicting outcomes. prospective, 16 days observational included 156 adults with injury. The bed, periwound skin and normal was recorded by using thermography every three days. After that, relative temperatures PI were analyzed. aim assess significance outcomes injuries. Relative between positively correlated (r > 0.64). Particularly first day follow up, it found be closely related = 0.687). On last median time (the eighth ninth day) optimal cutoff values indicator negative (periwound lower than skin). COX proportional hazard regression model analysis showed that on follow-up most significant predictor healing, risk increased largest- 8.79 times (95%CI: 4.53, 17.05), when its greater 0.000 °C. monitoring better visual which can objectively serve as an status

Language: Английский

Citations

1
Impact of professional experience on clinical judgment and muscular response in various neuromuscular tests DOI Creative Commons

Jorge Rey-Mota,

Guillermo Escribano-Colmena, Jesús Fernández‐Lucas

et al.

Physiology & Behavior, Journal Year: 2024, Volume and Issue: 283, P. 114602 - 114602

Published: June 6, 2024

Muscle testing is an integral component in assessing musculoskeletal function and tailoring rehabilitation efforts. This study aimed i. to identify objective evaluation system sensitive analyze changes different muscular conditions neuromuscular tests across a spectrum of professional experience levels; ii. differences parameters clinical judgment between participants levels expertise tests. Participants included 60 subjects with Level I III who performed blinded on the middle deltoid rectus femoris muscles 40 volunteer subjects. The methodology centered standardizing test protocols minimize variability, employing EMG quantify muscle activity, thermography capture thermographic response, digital dynamometry measure resistance. findings revealed that while traditional methods like electromyography provide valuable insights, stands out for its sensitivity detecting condition test. Moreover, data underscored pivotal role advanced training enhancing precision accuracy diagnostics, since there were significant Middle Rectus analyzed, presenting higher participant validated instrument.

Language: Английский

Citations

7
Infrared Thermography in Symptomatic Knee Osteoarthritis: Joint Temperature Differs Based on Patient and Pain Characteristics DOI Open Access
Luca De Marziani, Angelo Boffa, Lucia Angelelli

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(6), P. 2319 - 2319

Published: March 16, 2023

The aim of this study was to evaluate osteoarthritis (OA) patients with infrared thermography investigate imaging patterns as well demographic and clinical characteristics that influence knee inflammation. Forty one-sided symptomatic OA were included evaluated through knee-specific PROMs the PainDETECT Questionnaire for neuropathic pain evaluation. Thermograms captured using a thermographic camera FLIR-T1020 temperatures extracted software ResearchIR overall five ROIs: medial, lateral, medial patella, lateral suprapatellar. mean temperature total 31.9 ± 1.6 °C. It negatively correlated age (rho = −0.380, p 0.016) positively BMI 0.421, 0.007) IKDC objective score (tau 0.294, 0.016). Men had higher in suprapatellar areas (p 0.017, 0.019, 0.025, respectively). Patients lower area (31.5 1.0 vs. 32.3 1.1, 0.042), correlating 0.045). This demonstrated skin knees is influenced by patients, joint younger male worst scores affected pain.

Language: Английский

Citations

16
Exploring Thermal Dynamics in Wound Healing: The Impact of Temperature and Microenvironment DOI Creative Commons
Jun Huang,

Chunjie Fan,

Yindong Ma

et al.

Clinical Cosmetic and Investigational Dermatology, Journal Year: 2024, Volume and Issue: Volume 17, P. 1251 - 1258

Published: May 1, 2024

Abstract: Exploring the critical role of thermal dynamics in wound healing, this manuscript navigates through complex biological responses initiated upon infliction and how temperature variations influence healing trajectory. Integrating biothermal physics, clinical medicine, biomedical engineering, it highlights significance management care, emphasizing microenvironment's division into internal external domains their collaborative impact on tissue repair. Innovations real-time monitoring, especially intelligent wireless sensor dressings, are spotlighted as transformative, enabling precise condition management. The text underscores necessity for further research to elucidate regulation's molecular cellular mechanisms processes. It advocates standardized protocols localized heating treatments, integrating them personalized care strategies enhance therapeutic outcomes, improve patient well-being, achieve cost-effective healthcare practices. This work presents a forward-looking perspective refining sophisticated, evidence-based interventions, interplay between healing. Keywords: dynamics, microenvironment, treatment

Language: Английский

Citations

6
Stimuli-Responsive Drug Delivery Systems for Inflammatory Skin Conditions DOI Creative Commons

Luna Gade,

Ben J. Boyd, Martin Malmsten

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 187, P. 1 - 19

Published: Aug. 28, 2024

Inflammatory skin conditions highly influence the quality of life patients suffering from these disorders. Symptoms include red, itchy and painful lesions, which are visible to rest world, causing stigmatization a significantly lower mental health patients. Treatment options often unsatisfactory, as they suffer either low patient adherence or risk severe side effects. Considering this, there is need for new treatments, notably ways delivering drugs. Stimuli-responsive drug delivery systems able deliver their cargo in response given stimulus are, thus, promising treatment inflammatory conditions. For example, use external stimuli such ultraviolet light, near infrared radiation, alteration magnetic field enables release be precisely controlled space time. On other hand, internal induced by pathological condition, including pH upregulation reactive oxygen species enzymes, can utilized create that specifically target diseased achieve better efficacy safety. In latter context, however, it key importance match trigger mechanism system actual features specific condition. Hence, focus this article placed not only on reviewing stimuli-responsive developed treat conditions, but also critically evaluating context diseases. STATEMENT OF SIGNIFICANCE: Skin diseases affect one-third world's population, lowering patients, who deal with symptoms well due visibility symptoms. Current treatments hampered serious Therefore, more emphasis should developing innovative formulations provide safety hold considerable promise regard, where when needed, reducing adverse effects potentially offering outcomes.

Language: Английский

Citations

6
Thermal Imaging as a Method to Indirectly Assess Peripheral Vascular Integrity and Tissue Viability in Veterinary Medicine: Animal Models and Clinical Applications DOI Creative Commons
Daniel Mota‐Rojas, Asahi Ogi, Dina Villanueva‐García

et al.

Animals, Journal Year: 2023, Volume and Issue: 14(1), P. 142 - 142

Published: Dec. 31, 2023

Infrared thermography (IRT) is a technique that indirectly assesses peripheral blood circulation and its resulting amount of radiated heat. Due to these properties, thermal imaging currently applied in human medicine noninvasively evaluate vascular disorders such as thrombosis, thromboembolisms, other ischemic processes. Moreover, tissular damage (e.g., burn injuries) also causes microvasculature compromise. Therefore, can be determine the degree according viability tissues vessels, it used monitor skin transplant procedures grafting free flaps. The present review aims summarize analyze application IRT veterinary method assess integrity relation heat diagnostic for tissue viability, damage, wound care.

Language: Английский

Citations

11
Advancements in Dermatological Imaging Modalities DOI Creative Commons
Vishal Gaurav, Sushant Agrawal,

Aysha Najeeb

et al.

Indian Dermatology Online Journal, Journal Year: 2024, Volume and Issue: 15(2), P. 278 - 292

Published: Feb. 28, 2024

Language: Английский

Citations

4