Traceability Research on Dendrobium devonianum Based on SWATHtoMRM DOI Creative Commons
Tao Lin,

Xinglian Chen,

Lijuan Du

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(19), P. 3608 - 3608

Published: Sept. 28, 2023

SWATHtoMRM technology was used in this experiment to further identify and trace the sources of Dendrobium devonianum officinale produced same area using TOF MS-MRM. After conversion R package SWATHtoMRM, 191 MRM pairs positive ions 96 negative were obtained. can be separated very well PCA PLS-DA analysis ion pairs; shows that there are obvious differences chemical composition between officinale, which clearly proves pseudotargeted metabolomics method based on for traceability identification research. A total 146 characteristic compounds obtained, with 20 devonianum. The enrichment pathways mainly concentrated lipids atherosclerosis, chagas disease, fluid shear stress proteoglycans cancer, IL-17 signaling pathway, sphingolipid diabetic cardiomyopathy, arginine proline metabolism, etc., among lipid atherosclerosis more enriched, 11 affected expression levels IL-1, TNFα, CD36, IL-1β, etc. These as a reference research variety improvement active substance accumulation officinale.

Language: Английский

Chemical Constituents, Bioactivities, and Pharmacological Mechanisms of Dendrobium officinale: A Review of the Past Decade DOI
P Zhang, Xingyu Zhang, Xingyi Zhu

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2023, Volume and Issue: 71(41), P. 14870 - 14889

Published: Oct. 6, 2023

Dendrobium officinale, a plant in the Orchidaceae family, has been used traditional Chinese medicine for thousands of years. Sweet and slightly cold nature, it can invigorate stomach, promote fluid production, nourish Yin, dissipate heat. Over past decade, more than 60 compounds have derived from D. including flavonoids, bibenzyl, phenanthrene. Various studies explored underlying pharmacological mechanisms these compounds, which shown antitumor, hypoglycemic, hypertensive, gastrointestinal-regulatory, visceral organ protection, antiaging, neurorestorative effects. This paper presents systematic review structural classification, biological activity, different chemical components obtained officinale over decade. aims to provide reference future study establish foundation clinical applications. Furthermore, this identifies potential shortcomings current research as well directions methodologies research.

Language: Английский

Citations

23
Phytochemical analysis and investigation of antioxidant and anti-inflammatory activities of selected Ethiopian traditional medicinal plants DOI
Juhar Zemede,

Belay Melese,

Tegenu Mekuria

et al.

Journal of Herbal Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100984 - 100984

Published: Jan. 1, 2025

Language: Английский

Citations

0
Alkaloids extracted from Dendrobium officinale grown in diverse environments exhibited robust antioxidative and antiaging activity DOI
Yichen Liu, Arome Solomon Odiba,

Qi Yu

et al.

Journal of Future Foods, Journal Year: 2025, Volume and Issue: 5(6), P. 591 - 604

Published: Jan. 29, 2025

Language: Английский

Citations

0
Polyamine-containing natural products: structure, bioactivity, and biosynthesis DOI
Qingshan Long, Wen Zhou, Haibo Zhou

et al.

Natural Product Reports, Journal Year: 2023, Volume and Issue: 41(4), P. 525 - 564

Published: Oct. 24, 2023

Polyamine-containing natural products have been isolated from a wide range of terrestrial and marine organisms. Most them exhibit remarkable diverse activities with potential applications in human health agriculture.

Language: Английский

Citations

9
The spatiotemporal profile of Dendrobium huoshanense and functional identification of bHLH genes under exogenous MeJA using comparative transcriptomics and genomics DOI Creative Commons

Xiaomei He,

Wenwu Zhang, Irfan Ali Sabir

et al.

Frontiers in Plant Science, Journal Year: 2023, Volume and Issue: 14

Published: May 10, 2023

Alkaloids are one of the main medicinal components

Language: Английский

Citations

8
Metabolomics-Based Analysis of the Effects of Different Cultivation Strategies on Metabolites of Dendrobium officinale Kimura et Migo DOI Creative Commons
Yang Da,

Yeyang Song,

Anjin Lu

et al.

Metabolites, Journal Year: 2023, Volume and Issue: 13(3), P. 389 - 389

Published: March 6, 2023

Dendrobium officinale Kimura et Migo is a famous plant with high medicinal value which has been recorded in the Chinese Pharmacopoeia (2020 Edition). The properties of D. are based on its chemical composition. However, there no reports how different cultivation methods affect In order to reveal this issue, samples were collected study through tree epiphytic cultivation, stone and greenhouse cultivation. Polysaccharides determined by phenol sulfuric acid method secondary metabolites detected UPLC-MS technique. addition, regards metabolomics, we used multivariate analyses including principal component analysis (PCA) orthogonal partial least squares (OPLS-DA) screen for differential met conditions variable importance projection values >1, fold change >4, p < 0.05. taken further metabolic pathway enrichment analysis, was Kyoto Encyclopedia Genes Genomes (KEGG) database, validated antioxidant activity. Comparing three groups according standards ChP edition), results showed that polysaccharide content from stony significantly higher than live Metabolomic revealed 185 among 3 methods, 99 being highest strategies mainly effected four carbohydrate pathways, five metabolite synthesis six amino one nucleotide metabolism pathway, cofactor vitamin translation genetic information processing. Furthermore, had best activity implicated production. This effects composition also provided reference establishing quality control aid development utilization.

Language: Английский

Citations

7
Effects of Inonotus obliquus on ameliorating podocyte injury in ORG mice through TNF pathway and prediction of active compounds DOI Creative Commons
Zhaodi Han, Le Gong,

Yani Xue

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 21, 2024

Background Podocyte injury is a common pathologic mechanism in diabetic kidney disease (DKD) and obesity-related glomerulopathy (ORG). Our previous study confirmed that Inonotus obliquus (IO) improved podocyte on DKD rats. The current explored the pharmacological effects, related mechanisms possible active components of IO ORG mice. Methods Firstly, by combining ultra-high performance liquid chromatography tandem mass spectrometry analysis (UPLC-Q-TOF-MS) with network pharmacology to construct human protein-protein interaction enrich pathway, which led discover crucial against ORG. Then, mice were established high-fat diet biochemical assays, histopathology, Western blot used explore effects obesity injury. Finally, pharmacology-based findings immunohistochemistry. compositions absorbed plasma analyzed UPLC-Q-TOF-MS molecular docking was predict compounds. Results result suggested alleviated inflammatory response modulating TNF signal. 20-week vivo experiment glomerular hypertrophy, under electron microscopy, renal nephrin, synaptopodin, TNF-α IL-6 expressions blotting immunohistochemical staining. Other indicators such as body weight, serum total cholesterol, liver triglyceride also intervention. showed triterpenoids, including inoterpene F trametenolic acid, might be pharmacodynamic basis. Conclusion research based analysis, amelioration via its modulation Triterpenoids predicated acting components.

Language: Английский

Citations

2
Overview and limitations of database in global traditional medicines: A narrative review DOI
Xiaolan Li, Jianqing Zhang, Xuanjing Shen

et al.

Acta Pharmacologica Sinica, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 2, 2024

Language: Английский

Citations

1
Effect of storage temperature on the long term stability of Dendrobium catenatum Lindl. blended liquor DOI
Jiangbo Wang, Zhiwen Liu, Xiangrui Jiang

et al.

Journal of Food Measurement & Characterization, Journal Year: 2024, Volume and Issue: 18(4), P. 2618 - 2630

Published: Feb. 3, 2024

Language: Английский

Citations

1
Plant AT-rich protein and zinc-binding protein (PLATZ) family in Dendrobium huoshanense: identification, evolution and expression analysis DOI Creative Commons

Fangli Gu,

Yanshuang Ren,

Muhammad Aamir Manzoor

et al.

BMC Plant Biology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Dec. 30, 2024

PLATZ (plant A/T-rich protein and zinc-binding protein) transcription factors are essential for plant growth, development, responses to abiotic stress. The regulatory role of genes in the environmental adaptation D. huoshanense is inadequately comprehended. genome-wide identification elucidates functions processes gene family. Our investigation encompassed examination structures chromosome distribution, construction phylogenetic tree with its relatives, analysis cis-acting elements expression profiles potentially implicated growth stress responses. Eleven DhPLATZs were classified into three clades (I, II, III) according their evolutionary homology. distribution these over six chromosomes indicated that both whole genome duplication (WGD) segmental events have contributed expansion this Ka/Ks revealed a pattern purifying selection after occurrences, suggesting little alterations functional divergence. collinearity microsynteny results DhPLATZ shared same conserved domains as paralogs from chrysotoxum. Expression profiling quantitative demonstrated had unique patterns response phytohormones cold Subcellular localization expressed nucleus, factors. These findings enhance our understanding genes' involvement species underscore significance important areas further research.

Language: Английский

Citations

1