Restoring the missing person to personalized medicine and precision psychiatry

Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Feb. 9, 2023

Precision psychiatry has emerged as part of the shift to personalized medicine and builds on frameworks such U.S. National Institute Mental Health Research Domain Criteria (RDoC), multilevel biological “omics” data and, most recently, computational psychiatry. The is prompted by realization that a one-size-fits all approach inadequate guide clinical care because people differ in ways are not captured broad diagnostic categories. One first steps developing this treatment was use genetic markers pharmacotherapeutics based predictions pharmacological response or non-response, potential risk adverse drug reactions. Advances technology have made greater degree specificity precision potentially more attainable. To date, however, search for largely focused parameters. Psychiatric disorders involve multi-level dynamics require measures phenomenological, psychological, behavioral, social structural, cultural dimensions. This points need develop fine-grained analyses experience, self-construal, illness narratives, interpersonal interactional dynamics, contexts determinants health. In paper, we review limitations arguing it cannot reach its goal if does include core elements processes give rise psychopathological states, which agency experience person. Drawing from contemporary systems biology, epidemiology, developmental psychology, cognitive science, propose cultural-ecosocial integrating with person-centered care.

Language: Английский

---

Toward an embodied cognitive science of religion: enaction, evolution, emergence

Religion Brain & Behavior, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Dec. 20, 2024

To secure the scientific credibility of its theoretical foundations, CSR needs to update cognitive model. Seminal work in CSR, and much contemporary research, employs a model cognition that is subject mounting criticism (i.e., cognitivism). The most significant these critiques come from 4E cognition. This paper focuses on enactive cognition, arguing reconstructing along lines enactivism will put field firmer grounding can resolve long standing debates within field. Beginning with an in-depth critique key component cognitivist model, representationalism, also argues non-representational fits better evolutionary commitments CSR. Next, it considers case study reconstruction CSR: agency detection. foundational concept has under scrutiny due lack empirical support, raising concerns may need be abandoned. Enactivism recasts as "embodied agency-attunement." allows sensitivity continue role while addressing leveled against it. approach compared predictive processing concludes suggestions about next steps towards embodied

Language: Английский

---

Turn-Taking Mechanisms in Imitative Interaction: Robotic Social Interaction Based on the Free Energy Principle

Entropy, Journal Year: 2023, Volume and Issue: 25(2), P. 263 - 263

Published: Jan. 31, 2023

This study explains how the leader-follower relationship and turn-taking could develop in a dyadic imitative interaction by conducting robotic simulation experiments based on free energy principle. Our prior showed that introducing parameter during model training phase can determine leader follower roles for subsequent interactions. The is defined as w, so-called meta-prior, weighting factor used to regulate complexity term versus accuracy when minimizing energy. be read sensory attenuation, which robot’s beliefs about action are less sensitive evidence. current extended examines possibility shifts depending changes w phase. We identified space structure with three distinct types of behavioral coordination using comprehensive sweeps both robots interaction. Ignoring behavior follow their own intention was observed region ws were set large values. One robot leading, followed other one larger smaller. Spontaneous, random between at smaller or intermediate Finally, we examined case slowly oscillating anti-phase two agents experiment resulted switched determined sequences, accompanied periodic ws. An analysis transfer entropy found direction information flow also shifted along turn-taking. Herein, discuss qualitative differences random/spontaneous agreed-upon sequential reviewing synthetic empirical studies.

Language: Английский

---

How preferences enslave attention: calling into question the endogenous/exogenous dichotomy from an active inference perspective

Phenomenology and the Cognitive Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Language: Английский

---

On Embedded Normativity - An Active Inference account of agency beyond flesh

Published: June 1, 2023

We introduce and motivate the concept of \emph{embedded normativity} to account for externalization social norms in material environment through human activity. ground this notion Active Inference framework, more specifically derived Skilled Intentionality framework ecological perception action. This considers that skilled agent experience world as a landscape affordances, or opportunities is inherently normative, its tied agent's anticipations over own behaviour (and therefore, indirectly, motivations). emphasize given normativity does not exist inside outside boundaries, but brought about by engagement with world. discuss dynamics \emph{internalization} \emph{externalization} which agents come project onto elements their environment, simple attraction toward favoured states. Given account, we revisit earlier descriptions shared sociocultural niche enable broadcasting integration norms. Finally, how embedded can be into existence humans, relate our discussion ontological stance participatory realism.

Language: Английский

---

The cognitive archeology of sociocultural lifeforms

Published: March 17, 2023

We draw from the recent enactivist literature to articulate an operational definition of Wittgensteinien forms life as a self-productive collection constraints over collective behavior. propose that humans integrate and enact those account through Active Inference shared “regimes attentions”, which are experienced embedded normativity within direct engagement with sociocultural niche. Given elements, we discuss how lifeforms “encode information” in material niche, this information may be recovered by cognitive archeologists.

Language: Английский

---

If AI machine cannot think, can QI machine think?—from negative numbers to quantum intelligence for mind-light-matter unity

Quantum Machine Intelligence, Journal Year: 2023, Volume and Issue: 5(1)

Published: March 23, 2023

Language: Английский

---

The Inherent Normativity of Concepts

Minds and Machines, Journal Year: 2024, Volume and Issue: 34(4)

Published: Sept. 25, 2024

Language: Английский

---

Digitally embodied lifespan neurocognitive development and Tactile Internet: Transdisciplinary challenges and opportunities

Frontiers in Human Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Feb. 10, 2023

Mechanisms underlying perceptual processing and inference undergo substantial changes across the lifespan. If utilized properly, technologies could support buffer relatively more limited neurocognitive functions in still developing or aging brains. Over past decade, a new type of digital communication infrastructure, known as “Tactile Internet (TI),” is emerging fields telecommunication, sensor actuator machine learning. A key aim TI to enable humans experience interact with remote virtual environments through digitalized multimodal sensory signals that also include haptic (tactile kinesthetic) sense. Besides their applied focus, such may offer opportunities for research tapping into mechanisms digitally embodied perception cognition well how they differ age cohorts. However, there are challenges translating empirical findings theories about lifespan development day-to-day practices engineering technological development. On one hand, capacity efficiency affected by signal transmission noise according Shannon’s (1949) Information Theory. other neurotransmitters, which have been postulated means regulate signal-to-noise ratio neural information (e.g., Servan-Schreiber et al., 1990 ), decline substantially during aging. Thus, here we highlight neuronal gain control illustrate potential interfaces age-adjusted plausible multisensory embodiments cognitive interactions environments.

Language: Английский

---

On Embedded Normativity an Active Inference Account of Agency Beyond Flesh

Communications in computer and information science, Journal Year: 2023, Volume and Issue: unknown, P. 91 - 105

Published: Nov. 15, 2023

Language: Английский

---