Post-COVID Symptoms in Occupational Cohorts: Effects on Health and Work Ability

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(9), P. 5638 - 5638

Published: April 25, 2023

Post-acute COVID-19 syndrome is frequently observed in workers and has a substantial impact on work ability. We conducted health promotion program to identify cases of post-COVID syndrome, analyze the distribution symptoms their association with Of 1422 who underwent routine medical examination 2021, 1378 agreed participate. Among latter, 164 had contracted SARS-CoV-2 115 (70% those were infected) persistent symptoms. A cluster analysis showed that most characterized by sensory disturbances (anosmia dysgeusia) fatigue (weakness, fatigability, tiredness). In one-fifth these cases, additional included dyspnea, tachycardia, headache, sleep disturbances, anxiety, muscle aches. Workers found have poorer quality sleep, increased fatigue, depression, decreased ability compared whose rapidly disappeared. It important for occupational physician diagnose workplace since this condition may require temporary reduction tasks supportive treatment.

Language: Английский

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Effects of Aerobic Exercise Therapy through Nordic Walking Program in Lactate Concentrations, Fatigue and Quality-of-Life in Patients with Long-COVID Syndrome: A Non-Randomized Parallel Controlled Trial

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(4), P. 1035 - 1035

Published: Feb. 11, 2024

Background: Long-COVID syndrome comprises a variety of signs and symptoms that develop during or after infection with COVID-19 which may affect the physical capabilities. However, there is lack studies investigating effects in sport capabilities suffering from infection. The purpose study was to evaluate compare lactate concentration quality life (QoL) patients those who have not developed non-Long-COVID Nordic walking exercise therapy. Methods: Twenty-nine (25.5 ± 7.1 years) took part non-randomized controlled trial, divided into two groups: group (n = 16) control 13). Patients were confirmed as having if they experienced fatigue tiredness when performing daily activities worsening vigorous mental activity. All participants underwent 12-week Walking program. Lactate distance covered all sessions measured. Pre- Long-Nordic program, Modified Fatigue Impact Scale (MFIS), Short Form 36 Health Survey (SF-36), EURO QoL-5D (EQ-ED) administered assess life, respectively. Results: There effect between groups (F 5.604; p 0.024). no significant result session 3.521; 0.121) interaction × 1.345; 0.414). main 23.088; < 0.001), time 6.625; 0.026), 4.632; 0.002) on SF-36 scale noted. Also, 38.372; 12.424; 0.005), 4.340; 0.014) EQ-5D. only 26.235; 0.001) 2.265; 0.160) 1.584; 0.234) MFIS scale. Conclusions: showed higher compared 12 weeks presented decrease respect according scale, well improvement aerobic

Language: Английский

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Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-center, population-based cohort study

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 352, P. 296 - 305

Published: Feb. 13, 2024

Depression and fatigue are commonly observed sequelae following viral diseases such as COVID-19. Identifying symptom constellations that differentially classify post-COVID depression may be helpful to individualize treatment strategies. Here, we investigated whether self-reported associated with the same or different constellations. To address this question, used data from COVIDOM, a population-based cohort study conducted part of NAPKON-POP platform. Data was collected in three German regions (Kiel, Berlin, Würzburg). We analyzed >2000 individuals at least six months past PCR-confirmed COVID-19 disease, using elastic net regression cluster analysis. The model developed Kiel set, externally validated sets Berlin Würzburg. Our results revealed overlapping consisting difficulties daily activities, perceived health-related quality life, chronic exhaustion, unrestful sleep, impaired concentration. Confirming overlap constellations, follow-up analysis could categorize scoring high low on but not differentiate between both dimensions. presented cross-sectional, primarily questionnaire medical records rather than biometrically data. In summary, our suggest strong link thus highlighting need for integrative approaches.

Language: Английский

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Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea

Journal of Neural Transmission, Journal Year: 2024, Volume and Issue: 131(3), P. 203 - 212

Published: Feb. 12, 2024

Abstract Cognitive impairment, depression and (mental) fatigue represent the most frequent neuropsychiatric symptoms of post-COVID syndrome. Neuroinflammation, oxidative stress mitochondrial dysfunction have been identified as common pathophysiological mechanisms underlying these symptoms. Attempts to treat post-COVID-associated cognitive impairment with different drugs available for other diseases not yet successful. One probable explanation could be that work by one specific mechanism action only in a broad multi-target way. Therefore, they will address spectrum possibly responsible Notably, nearly all currently under investigation syndrome are rather addressing single target instead several pathomechanisms this condition. Contrary approach, herbal often consist many ingredients pharmacological properties targets. might promising approach treatment symptomatic presentation following SARS-CoV-2 infection. Of drugs, extracts Ginkgo biloba Rhodiola rosea probably best investigated candidates. Their vitro vivo includes anti-oxidative, anti-inflammatory, antidepressant well reducing fatigue. In studies, both showed positive effects on physical mental impaired cognition. Moreover, depressive were also reduced some studies. However, even if results promising, data still preliminary require additional proof further

Language: Английский

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Unveiling the Clinical Spectrum of Post-COVID-19 Conditions: Assessment and Recommended Strategies

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 23, 2024

SARS-CoV-2 caused the pandemic of rapidly evolving COVID-19. As December 6, 2023, there were 765,152,854 COVID-19-recovering cases. Long-term consequences known as "long COVID" and "post-COVID-19 conditions" (PCCs) or "post-acute COVID-19 syndrome" are being reported more frequently in a subset recovering patients. Systemic, neuropsychiatric, cardio-respiratory, gastrointestinal symptoms most prevalent. The management PCCs poses unique challenges due to lack official guidelines complex nature illness. This abstract highlights key principles derived from recent reviews expert recommendations provide healthcare professionals with comprehensive approach manage post-COVID-19 Preventive medicine plays crucial role managing PCCs. While no specific medications available for treatment, preventive measures such vaccination, adherence precautionary measures, regular consultations medical professionals, monitoring progress, seeking information on symptom essential assist patients their recovery improve quality life. Medical requires transparent goal-setting collaborative decision-making based patient's symptoms, comorbidities, treatment objectives. Treatment plans should focus patient education, using registries calendars track triggers, providing support reassurance, offering holistic through peer networks supportive psychotherapy techniques. Symptomatic rehabilitative care, including well-established techniques, physical rehabilitation programs, addressing mental health well-being, vital components management. Lifestyle factors stress reduction, nutrition, sleep be incorporated into underlying conditions Regular follow-up visits referrals specialists recommended monitor progress address organ system involvement additional care needs. In summary, effective PCCs, include psychotherapy, symptomatic management, counseling lifestyle elements, appropriate plans. However, it is stay updated authorities evidence-based

Language: Английский

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Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airways diseases in the UK: a multicentre, longitudinal cohort study (PHOSP-COVID)

ERJ Open Research, Journal Year: 2024, Volume and Issue: 10(4), P. 00982 - 2023

Published: March 28, 2024

The long-term outcomes of COVID-19 hospitalisation in individuals with pre-existing airway diseases are unknown.

Language: Английский

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Determinants of post-acute COVID-19 syndrome among hospitalized severe COVID-19 patients: A 2-year follow-up study

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(5), P. e0298409 - e0298409

Published: May 10, 2024

Background Post-acute COVID-19 syndrome is a condition where individuals experience persistent symptoms after the acute phase of infection has resolved, which lowers their quality life and ability to return work. This study assessed prevalence associated risk factors post-acute (PACS) among severe patients who were discharged from Millennium Care Center, Addis Ababa, Ethiopia. Methods A cross-sectional using data collected patient charts follow-up telephone interview two years discharge. Systematic random sampling was used select total 400 patients. structured questionnaire developed case report form for PACS World Health Organization (WHO) used. Frequency cross-tabulation descriptive statistics. Predictor variables with p-value <0.25 in bivariate analyses included logistic regression. Result Out patients, 20 dead, 14 refused give consent, 26 couldn’t be reached because phones weren’t working. Finally, 340 study. The majority (68.5%) males mean age 53.9 (±13.3 SD) years. More than third (38.1%) reported persistence at least one symptom hospital most common fatigue (27.5%) Cough (15.3%). Older (AOR 1.04, 95% CI 1.02–1.07), female sex 1.82, 1.00–3.29), presence comorbidity 2.38, 1.35–4.19), alcohol use 3.05, 1.49–6.26), presentation 2.18, 1.21–3.95), longer stay 1.06, 1.02–1.10) found increase odds developing syndrome. Higher hemoglobin level decrease subsequent 0.84, 0.71–0.99). Conclusion high, wide range experienced by survivors identified are more susceptible require targeted monitoring care multidisciplinary approach.

Language: Английский

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Fatigue after COVID‐19 in non‐hospitalized patients according to sex

Brain and Behavior, Journal Year: 2023, Volume and Issue: 13(2)

Published: Jan. 9, 2023

Abstract Background Limited evidence exists on sex differences in post‐COVID fatigue among non‐hospitalized patients. Therefore, aim of the study was to evaluate course chronic symptoms subjects with SARS‐CoV‐2 infection, according sex. Methods Patients and staff from University Hospital Krakow anonymously retrospectively completed neuropsychological questionnaire that included eight syndrome. The presence these assessed before COVID‐19 0–4, 4–12, >12 weeks postinfection. inclusion criteria were as follows: age 18 or more years, since onset diagnosis confirmed by RT‐PCR anasopharyngeal swab. Results We 303 patients (79.53% women, 47.52% medical personnel) after a median 30 (interquartile range: 23–35) symptoms. A higher prevalence at least one symptom found females all time intervals compared males ( p < .036). Women, men, often experienced persistent fatigue, not caused effort persisting rest (for <4 weeks, odds ratio [OR] = 2.31, 95% confidence interval [CI]: 1.13–4.73; for 4–12 OR 1.95, CI: 1.06–3.61), non‐restorative sleep 2.17, 1.23–3.81; 1.03–3.71), sore throat 1.97, 1.03–3.78; 2.76, 1.05–7.27). Sex headache, arthralgia, prolonged postexercise observed only during first 4 (OR 2.59, 1.45–4.60, 2.97, 1.02–8.64, 1.87, 1.01–3.51, respectively). There no between women men myalgia self‐reported lymph node enlargement. Conclusions differs significantly sexes individuals COVID‐19, suffering rest, sleep, throat.

Language: Английский

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Long COVID: An approach to clinical assessment and management in primary care

South African Family Practice, Journal Year: 2023, Volume and Issue: 65(1)

Published: June 23, 2023

Long COVID is an emerging public health threat, following swiftly behind the surges of acute infection over course COVID-19 pandemic. It estimated that there are already approximately 100 million people suffering from globally, 0.5 whom South African, and for our incomplete understanding condition has forestalled appropriate diagnosis clinical care. There several leading postulates complex, multi-mechanistic pathogenesis COVID. Patients with may present a diversity phenotypes, often significant overlap, which exhibit temporal heterogeneity evolution. Post-acute care follow-up, targeted screening, diagnosis, broad initial assessment more directed subsequent assessments necessary at primary level. Symptomatic treatment, self-management rehabilitation mainstays However, evidence-based pharmacological interventions prevention treatment beginning to emerge. This article presents rational approach assessing managing patients in setting.

Language: Английский

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Intrarelationships between suboptimal health status and anxiety symptoms: A network analysis

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 354, P. 679 - 687

Published: March 23, 2024

Suboptimal health status is a global public concern of worldwide academic interest, which an intermediate between and illness. The purpose the survey to investigate relationship anxiety statuses suboptimal identify central symptoms bridge symptoms.

Language: Английский

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