medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: July 3, 2023
ABSTRACT
A
timely
diagnosis
of
autism
is
paramount
to
allow
early
therapeutic
intervention
in
preschoolers.
Deep
Learning
(DL)
tools
have
been
increasingly
used
identify
specific
autistic
symptoms,
and
offer
promises
for
automated
detection
at
an
age.
Here,
we
leverage
a
multi-modal
approach
by
combining
two
neural
networks
trained
on
video
audio
features
semi-standardized
social
interactions
sample
160
children
aged
1
5
years
old.
Our
ensemble
model
performs
with
accuracy
82.5%
(F1
score:
0.816,
Precision:
0.775,
Recall:
0.861)
ASD
screening.
Additional
combinations
our
were
developed
achieve
higher
specificity
(92.5%,
i.e.,
few
false
negatives)
or
sensitivity
(90%,
i.e.
positives).
Finally,
found
relationship
between
the
network
modalities
versus
characteristics,
bringing
evidence
that
implementation
was
effective
taking
into
account
different
are
currently
standardized
under
gold
standard
assessment.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: June 13, 2023
Autism
spectrum
disorder
(ASD)
presents
a
neurological
and
developmental
that
has
an
impact
on
the
social
cognitive
skills
of
children
causing
repetitive
behaviours,
restricted
interests,
communication
problems
difficulty
in
interaction.
Early
diagnosis
ASD
can
prevent
from
its
severity
prolonged
effects.
Federated
learning
(FL)
is
one
most
recent
techniques
be
applied
for
accurate
diagnoses
early
stages
or
prevention
long-term
In
this
article,
FL
technique
been
uniquely
autism
detection
by
training
two
different
ML
classifiers
including
logistic
regression
support
vector
machine
locally
classification
factors
adults.
Due
to
FL,
results
obtained
these
have
transmitted
central
server
where
meta
classifier
trained
determine
which
approach
Four
patient
datasets,
each
containing
more
than
600
records
effected
adults
repository
features
extraction.
The
proposed
model
predicted
with
98%
accuracy
(in
children)
81%
adults).
Health Information Science and Systems,
Journal Year:
2023,
Volume and Issue:
11(1)
Published: Aug. 14, 2023
Autism
Spectrum
Disorder
(ASD)
is
a
complex
neurodevelopmental
disease
that
impacts
child's
way
of
behavior
and
social
communication.
In
early
childhood,
children
with
ASD
typically
exhibit
symptoms
such
as
difficulty
in
interaction,
limited
interests,
repetitive
behavior.
Although
there
are
disease,
most
people
do
not
understand
these
therefore
have
enough
knowledge
to
determine
whether
or
child
has
ASD.
Thus,
detection
based
on
accurate
diagnosis
model
Artificial
Intelligence
(AI)
techniques
critical
process
reduce
the
spread
control
it
early.
Through
this
paper,
new
Diagnostic
(DASD)
strategy
presented
quickly
accurately
detect
children.
DASD
contains
two
layers
called
Data
Filter
Layer
(DFL)
(DL).
Feature
selection
outlier
rejection
processes
performed
DFL
filter
dataset
from
less
important
features
incorrect
data
before
using
diagnostic
method
DL
diagnose
patients.
DFL,
Binary
Gray
Wolf
Optimization
(BGWO)
technique
used
select
significant
set
while
Genetic
Algorithm
(BGA)
eliminate
invalid
training
data.
Then,
Ensemble
Diagnosis
Methodology
(EDM)
precisely
main
contribution
EDM
consists
several
models
including
Enhanced
K-Nearest
Neighbors
(EKNN)
one
them.
EKNN
represents
hybrid
consisting
three
methods
(KNN),
Naïve
Bayes
(NB),
Chimp
(COA).
NB
weighed
convert
feature
space
weight
space.
COA
generation
size
dataset.
Finally,
KNN
applied
reduced
small
size.
blood
tests
test
proposed
against
other
recent
strategies
[1].
It
concluded
superior
many
performance
measures
accuracy,
error,
recall,
precision,
micro_average
macro_average
F1-measure,
implementation-time
values
equal
0.93,
0.07,
0.83,
0.82,
0.80,
0.79,
0.81,
1.5
s
respectively.
Autism
spectrum
disorder
(ASD)
is
a
global
concern,
with
prevalence
rate
of
approximately
1
in
36
children
according
to
estimates
from
the
Centers
for
Disease
Control
and
Prevention
(CDC).
Diagnosing
ASD
poses
challenges
due
absence
definitive
medical
test.
Instead,
doctors
rely
on
comprehensive
evaluation
child's
developmental
background
behavior
reach
diagnosis.
Although
can
occasionally
be
identified
aged
18
months
or
younger,
reliable
diagnosis
by
an
experienced
professional
typically
made
age
two.
Early
detection
crucial
timely
interventions
improved
outcomes.
In
recent
years,
field
early
has
been
greatly
impacted
emergence
deep
learning
models,
which
have
brought
about
revolution
improving
accuracy
efficiency
detection.
The
objective
this
review
paper
examine
progress
through
utilization
multimodal
techniques.
analysis
revealed
that
integrating
multiple
modalities,
including
neuroimaging,
genetics,
behavioral
data,
key
achieving
higher
It
also
evident
that,
while
neuroimaging
data
holds
promise
potential
contribute
detection,
it
most
effective
when
combined
other
modalities.
Deep
their
ability
analyze
complex
patterns
extract
meaningful
features
large
datasets,
offer
great
addressing
challenge
Among
various
models
used,
CNN,
DNN,
GCN,
hybrid
exhibited
encouraging
outcomes
ASD.
highlights
significance
developing
accurate
easily
accessible
tools
utilize
artificial
intelligence
(AI)
aid
healthcare
professionals,
parents,
caregivers
symptom
recognition.
These
would
enable
interventions,
ensuring
necessary
actions
are
taken
during
initial
stages.
e-Prime - Advances in Electrical Engineering Electronics and Energy,
Journal Year:
2024,
Volume and Issue:
8, P. 100602 - 100602
Published: May 18, 2024
The
diagnosis
and
classification
of
autism
spectrum
disorder
(ASD)
presents
anatomical
difficulty
owing
to
the
existence
a
wide
range
symptoms
that
may
be
organized
into
many
categories.
present
research
investigates
efficacy
machine
learning
methods
for
facilitating
recognition
individuals
who
have
been
diagnosed
with
ASD.
primary
aim
this
study
has
assess
effectiveness
multiple
algorithms
based
on
in
identifying
intricate
patterns
seen
datasets
related
ASD,
which
includes
diagnostic
results
indicate
Logistic
Regression
approach
demonstrated
great
levels
accuracy,
rates
94.3%
children
99%
adolescents
binary
system.
Similarly,
it
reported
Support
Vector
Machine
(SVM)
had
superior
performance
compared
all
other
systems
test
focused
adults
exclusively,
an
accuracy
rate
98.5%.
Moreover,
supplementary
series
experiments
conducted
combined
dataset
children,
adolescents,
resulted
observation
SVM
exhibited
notable
97.2%
99.55%
multiclass
classification,
encompassing
from
diverse
age
groups.
provide
evidence
favor
progress
achieved
treatment
ASD
as
result
capacity
detect
categorize
at
earlier
developmental
phase.
IEEE Transactions on Affective Computing,
Journal Year:
2023,
Volume and Issue:
14(4), P. 2982 - 3000
Published: Jan. 23, 2023
Behavioral
observation
plays
an
essential
role
in
the
diagnosis
of
Autism
Spectrum
Disorder
(ASD)
by
analyzing
children's
atypical
patterns
social
activities
(e.g.,
impaired
interaction,
restricted
interests,
and
repetitive
behavior).
To
date,
this
process
still
heavily
relies
on
questionnaire
survey,
clinical
observation,
or
retrospective
video
analysis,
leading
to
high
demand
for
professionals
with
massive
labor
costs.
This
article
proposes
a
standardized
platform
stimulating,
gathering,
analyzing,
modeling,
interpreting
human
behavioral
data
application
computer-aided
ASD
diagnosis.
By
structured
assessment
process,
proposed
system
can
automatically
evaluate
multiple
interaction
skills
using
captured
audio-visual
provide
final
diagnostic
suggestions.
We
collect
multimodal
database
95
participants
(71
children
24
age-matched
typical
controls)
real
clinic
environment,
Third
Affiliated
Hospital
Sun
Yat-sen
University,
China.
On
database,
our
obtains
accuracy
88.42%
identifying
average
age
months,
representing
performance
comparable
top-level
experts.
As
unified
replicable
solution,
it
has
good
potential
be
promoted
less
developed
areas
limited
high-quality
medical
resources.
Psychiatry Research,
Journal Year:
2025,
Volume and Issue:
344, P. 116353 - 116353
Published: Jan. 5, 2025
Early
screening
for
autism
spectrum
disorder
(ASD)
is
crucial,
yet
current
assessment
tools
in
Chinese
primary
child
care
are
limited
efficacy.
This
study
aims
to
employ
machine
learning
algorithms
identify
key
indicators
from
the
20-item
Modified
Checklist
Autism
Toddlers,
revised
(M-CHAT-R)
combining
with
ASD-related
sociodemographic
and
environmental
factors,
distinguish
ASD
typically
developing
children.
Data
our
prior
validation
of
M-CHAT-R
(August
2016-March
2017,
n
=
6,049
toddlers)
were
reviewed.
We
extracted
data
integrated
17
risk
factors
associated
development
strengthen
M-CHAT-R's
screening.
Five
feature
selection
methods
used
extract
subsets
original
set.
Six
applied
optimal
subset
distinguishing
clinically
diagnosed
toddlers
toddlers.
Nine
features
grouped
into
three
subsets:
1
contained
unanimously
recommended
items
(A1
[Follows
point],
A3
[Pretend
play],
A9
[Brings
objects
show],
A10
[Response
name]
A16
[Gazing
following]).
Subset
2
added
two
(A17
[Gaining
parent's
attention]
A18
[Understands
what
said]),
3
included
more
(A8
[Interest
other
children]
child's
age).
The
top-performing
algorithm
resulted
a
seven-item
classifier
92.5
%
sensitivity,
90.1
specificity,
10.0
positive
predictive
value.
Machine
classifiers
effectively
differentiate
using
reduced
item
highlights
clinical
significance
learning-optimized
models
health
centers
broader
applications.
International Journal of Scientific Research in Science and Technology,
Journal Year:
2025,
Volume and Issue:
12(1), P. 213 - 227
Published: Jan. 27, 2025
Autism
Spectrum
Disorder
is
one
of
the
biggest
concerns
in
healthcare
sector,
and
it’s
crucial
to
diagnose
it
at
an
early
stage
for
patients
with
Disorder.
This
review
focuses
on
use
machine
learning
diagnosing
Disorder,
drawing
data
from
100
papers
between
2015
2024.
We
touched
every
possible
method
starting
classic
ones
like
Support
Vector
Machines
(SVMs)
new
federated
learning.
Proving
actually
great
since
very
precise
(up
98%)
while
keeping
people’s
information
personal,
which
a
matter
industry.
But
cannot
write-off
basic
framework
where
people
standard
models
such
as
SVMs,
this
point
achieve
around
92%
accuracy.
Also,
they
are
more
convenient
be
implemented
small
clinics
that
do
not
possess
many
computers,
etcetera.
suggests
most
suitable
ML
approaches
detection
need
consider
accuracy,
privacy
availability
resources.
Lately,
developed
technologies
provide
even
better
outcomes;
nevertheless,
conventional
techniques
terrific
options
without
much
complicated
systems
available.
Thus,
study
offers
meaningful
suggestions
facilitate
choice
methods
based
comparison
these
approaches.
In
sum,
spans
existing
gap
research
advancements
state-of-art
practical
settings
provides
important
recommendations
enhancing
screening
across
various
contexts.