Kinetics and toxicity of nanoplastics in ex vivo exposed human whole blood as a model to understand their impact on human health DOI Creative Commons
Jéssica Arribas Arranz, A. Villacorta, Laura Rubio

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 948, P. 174725 - 174725

Published: July 14, 2024

The ubiquitous presence of nanoplastics (NPLs) in the environment is considered great health concern. Due to their size, NPLs can cross both intestinal and pulmonary barriers and, consequently, blood compartment expected. Understanding interactions between human components required. In this study, simulate more adequate real exposure conditions, whole healthy donors was exposed five different NPLs: three polystyrene approximately 50 nm (aminated PS-NH

Language: Английский

Microplastic production, distribution, and removal from the environment: a review DOI
Yu. V. Ioni,

Muhammad Farooq,

D. Roshka

et al.

Russian Chemical Reviews, Journal Year: 2025, Volume and Issue: 94(3), P. RCR5155 - RCR5155

Published: March 1, 2025

The presence of microplastics (MPs) in the environment is a highly relevant and aggravating environmental problem, which concern not only for specialists various fields but also everyone who cares about future Earth. ever-increasing production polymers expanding use plastic products enlarged MP concentrations Earth's ecosystem. need to control accumulation spread MPs caused by current crisis where no microplastic-free areas have remained on number studies dealing with existing potential threat living organisms from consumption increasing every year. aim this review systematize available information occurrence briefly describe main types polymer materials acting as sources mechanisms formation transport environment. hazardous behaviour analyzed considering their impact physiology aquatic soil organisms. Special emphasis demonstrating adverse effect emissions 3D printing materials. An overview methods capture given facilitate analysis development more reliable removal disposal. As result review, we assess long-term human health consequences exposure. Understanding formation, lifecycle environment, ways interaction will controlling design implementation effective techniques remediation prevent ecological consequences. <br>The bibliography includes 244 references.

Language: Английский

Citations

1

Microplastics induced inflammation in the spleen of developmental Japanese quail (Coturnix japonica) via ROS-mediated p38 MAPK and TNF signaling pathway activation1 DOI
Qingyu Zhang, Yuxin Zhang,

Lingyang Jing

et al.

Environmental Pollution, Journal Year: 2023, Volume and Issue: 341, P. 122891 - 122891

Published: Nov. 9, 2023

Language: Английский

Citations

18

Unraveling the micro- and nanoplastic predicament: A human-centric insight DOI
Sybren De Boever, Lindsey Devisscher, Mathieu Vinken

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 916, P. 170262 - 170262

Published: Jan. 20, 2024

Language: Английский

Citations

8

Pollutants, microbiota and immune system: frenemies within the gut DOI Creative Commons
Pierluigi Rio, Antonio Gasbarrini,

Giovanni Gambassi

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: May 10, 2024

Pollution is a critical concern of modern society for its heterogeneous effects on human health, despite widespread lack awareness. Environmental pollutants promote several pathologies through different molecular mechanisms. Pollutants can affect the immune system and related pathways, perturbing regulation triggering pro-inflammatory responses. The exposure to also leads alterations in gut microbiota with decreasing abundance beneficial microbes, such as short-chain fatty acid-producing bacteria, an overgrowth species. subsequent intestinal barrier dysfunction, together oxidative stress increased inflammatory responses, plays role pathogenesis gastrointestinal diseases. Moreover, encourage inflammation-dysplasia-carcinoma sequence various mechanisms, stress, dysregulation cellular signalling cell cycle impairment genomic instability. In this narrative review, we will describe interplay between pollutants, microbiota, system, focusing their relationship bowel diseases colorectal cancer. Understanding biological mechanisms underlying health-to-disease transition may allow design public health policies aimed at reducing burden disease pollutants.

Language: Английский

Citations

8

Kinetics and toxicity of nanoplastics in ex vivo exposed human whole blood as a model to understand their impact on human health DOI Creative Commons
Jéssica Arribas Arranz, A. Villacorta, Laura Rubio

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 948, P. 174725 - 174725

Published: July 14, 2024

The ubiquitous presence of nanoplastics (NPLs) in the environment is considered great health concern. Due to their size, NPLs can cross both intestinal and pulmonary barriers and, consequently, blood compartment expected. Understanding interactions between human components required. In this study, simulate more adequate real exposure conditions, whole healthy donors was exposed five different NPLs: three polystyrene approximately 50 nm (aminated PS-NH

Language: Английский

Citations

6