Exploration of the Muribaculaceae Family in the Gut Microbiota: Diversity, Metabolism, and Function

Nutrients, Journal Year: 2024, Volume and Issue: 16(16), P. 2660 - 2660

Published: Aug. 12, 2024

The gut microbiota are mainly composed of

Language: Английский

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Fermented Feed in Broiler Diets Reduces the Antinutritional Factors, Improves Productive Performances and Modulates Gut Microbiome—A Review

Agriculture, Journal Year: 2024, Volume and Issue: 14(10), P. 1752 - 1752

Published: Oct. 4, 2024

The aim of this review is to highlight the most beneficial effects dietary fermented feed in correlation with decreasing antinutrient concentration vegetal matrices usually used for broiler nutrition. Rational formulation critical animals because it improves animal performance, and provides necessary nutrients develop strong bones, muscles tissues, a properly functioning immune system. Fermentation useful as compounds high molecular mass are converted into energy lower presence enzymes produced mainly by bacteria yeasts. products contain probiotic on health microbiome. Feed fermentation has other roles such converting antinutrients substances organisms, some studies have shown that decreases risk components presence. For bibliographic research, different platforms were (PubMed, Science Direct, MDPI resources), numerous words or combinations terms find latest information. Fermented utilization been enhance growth performance while promoting healthier gut microbiome animals.

Language: Английский

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Fermented Kamut Wheat Diet Prevents DSS-Induced Colitis via Modulating Gut Microbiota in Mice

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3017 - 3017

Published: March 26, 2025

Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disorder of the gastrointestinal tract with limited treatment options. This study investigates preventive effects fermented Kamut wheat enzyme (FKW) diet on progression dextran sulfate sodium (DSS)-induced colitis in mice, focus gut microbiota modulation cytokine regulation. Female C57BL/6J mice were divided into groups fed consisting either FKW (containing 39.80% FKW) or control under 1.25% 2.50% DSS conditions. The was formulated based AIN-93G standard rodent formula, providing comparable amounts total proteins, crude lipids, dietary fibers as diet. effectively mitigated colitis, evidenced by improvements key indicators such intake, body weight, colon length, stool consistency, bleeding, particularly group. Histopathological analysis revealed preservation colonic architecture reduced mucosal damage also resulted significant reduction pro-inflammatory cytokines (TNF-α, IL-6, IL-1β, IFN-γ) myeloperoxidase (MPO) levels, coupled an increase anti-inflammatory IL-10. Gut showed increased abundance beneficial bacteria Muribaculaceae, Lachnospiraceae NK4A136 Bacteroides acidifaciens decreased pathogenic like Escherichia/Shigella Bilophila. These findings underscore potential intervention for mitigating emphasizing role supporting intestinal health. results highlight FKW's to reduce risk development, foundation future research its applications.

Language: Английский

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Bacillus spp. as potential probiotics: promoting piglet growth by improving intestinal health

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: July 26, 2024

The application of

Language: Английский

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Effects of fermented unconventional protein feed on pig production in China

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: July 31, 2024

Unconventional protein feeds, characterized by low nutritional value, high variability, and poor palatability, have limited their application in swine production. Fermentation technology holds the key to addressing these shortcomings. Given ban on antibiotics China, inferior quality of imported pig breeds, long-term dependence soybean, prospects for fermented unconventional feeds are promising. This paper delves into common types factors influencing fermentation process, mechanisms which they enhance health, challenges offering theoretical insights future development feed industry.

Language: Английский

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The Effects of Fermented Cauliflower Residue Feed on the Diarrhea Rate, Intestinal Morphology, Immune Indicators, and Intestinal Flora of Weaned Piglets

Fermentation, Journal Year: 2024, Volume and Issue: 10(9), P. 465 - 465

Published: Sept. 9, 2024

This study investigated the effects of incorporating fermented feed into post-weaning piglet diet, with a focus on its impact growth, health, serum markers, immune function, diarrhea rate, and microbial community piglets. Forty-two piglets (Duroc × [Landrace Yorkshire], castrated male), good health similar weight (11.40 ± 1.36 kg) at 40 days age, were randomly assigned to two groups. Throughout trial, one group received standard diet (control group) while other was given supplemented (experimental group), respectively. The findings revealed that compared control group, fed showed increased daily gain. also led an increase in height villi duodenum or jejunum (p < 0.05), accompanied by improved ratio villus crypt depth experimental 0.05). Furthermore, enhanced richness diversity intestinal particularly increasing relative abundance Lactobacillaceae Bifidobacteriaceae. These demonstrate can reduce improve growth performance, enhance promote development

Language: Английский

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Overexpression of miRNA29a gene inhibits proliferation and promotes apoptosis of jejunal epithelial cells in yak

Animal Biotechnology, Journal Year: 2024, Volume and Issue: 35(1)

Published: Sept. 2, 2024

MicroRNAs (miRNAs) were identified to be involved in various biological functions by regulating the degradation or suppressing translation of their downstream target genes. Recent studies have miR-29a play a key role mammal cell differentiation, proliferation, apoptosis, and signal transduction. However, underlying for jejunal epithelial cells function still investigated. In order explore yak proliferation barrier dysfunction with over expression gene, three 0-day-old Pamir male yaks randomly selected slaughtered present study, isolated cultured determine protein composition on differential gene plateau. Here, we demonstrated that overexpression could inhibit jejunum cells, contribute apoptosis some extent. A total 133 differentially expressed proteins different groups label-free Mass Spectrometry (MS), which concluded two predominant themes: inflammatory response. Interestingly, GPR41, as bridge protein, was contacted themes Yaks mechanical PPI network, displayed strong mutual interactions complex network. Overall, our study suggested over-expression inhibited expressions specific proteins, damaged slow down intestine structure advanced mature development during young livestock period influence enhanced performance production efficiency.

Language: Английский

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Solubilized β-Glucan Supplementation in C57BL/6J Mice Dams Augments Neurodevelopment and Cognition in the Offspring Driven by Gut Microbiome Remodeling

Foods, Journal Year: 2024, Volume and Issue: 13(19), P. 3102 - 3102

Published: Sept. 28, 2024

A maternal diet rich in dietary fiber, such as β-glucan, plays a crucial role the offspring’s acquisition of gut microbiota and subsequent shaping its microbiome profile metabolome. This turn has been shown to aid neurodevelopmental processes, including early microglial maturation immunomodulation via metabolites like short chain fatty acids (SCFAs). study aimed investigate effects oat β-glucan supplementation, solubilized by citric acid hydrolysis, from gestation adulthood. Female C57BL/6J mice were orally supplemented with soluble (ObG) or carboxymethyl cellulose (CMC) drinking water at 200 mg/kg body weight during breeding while control group received 50 cellulose. ObG supplementation increased butyrate production guts both dams 4-week-old pups, attributing alterations profile. One-week-old pups showed markers similar four-week-old that also exhibited serum metabolism anti-inflammatory cytokines. Notably, 8 weeks, ObG-supplemented highest levels spatial memory cognition compared CMC groups. These findings suggest potential enhancement neonatal neurodevelopment early-life profile, later-life cognitive function.

Language: Английский

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Optimization of Fermentation Process of Zanthoxylum bungeanum Seeds and Evaluation of Acute Toxicity of Protein Extract in Mice

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4004 - 4004

Published: Dec. 11, 2024

The seeds of Zanthoxylum bungeanum seeds, a high-quality vegetable protein source, encounter application limitations due to their high molecular weight and anti-nutritional factors. This study focused on optimizing the fermentation process by investigating key parameters such as inoculation amount, ratio, material-to-liquid temperature, time. Both single-factor experiments response surface methodology were used determine optimal conditions. effects particle size, morphology (scanning electron microscopy), water holding capacity, oil solubility, emulsification properties seed analyzed. In addition, acute toxicity was investigated at doses 1.5 g/kg, 3 6 12 g/kg. results showed that conditions an inoculum concentration 10%, ratio Bacillus subtilis Lactobacillus plantarum 1:1, 0.8:1, temperature 35 °C, period 4 days. Under these optimized conditions, soluble content reached 153.1 mg/g. After fermentation, functional improved significantly: capacity increased 89%, 68%, while emulsifying activity stability indices 6% 17%, respectively. macromolecular proteins in effectively broken down into smaller fragments during resulting more folded porous structure. tests, all mice treated with fermented Zanthoxum survived for than 7 days after injection, there no significant differences body weight, organ index, hematological tests between groups, but FZBSP g/kg~12 g/kg caused varying degrees steatosis inflammatory damage heart liver. conclusion, this confirms follow-up pilot studies using have potential further development utilization.

Language: Английский

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