Bioinorganic Nanoparticles for the Remediation of Environmental Pollution: Critical Appraisal and Potential Avenues

Bioinorganic Chemistry and Applications, Journal Year: 2023, Volume and Issue: 2023, P. 1 - 26

Published: April 10, 2023

Nowadays, environmental pollution has become a critical issue for both developed and developing countries. Because of excessive industrialization, burning fossil fuels, mining exploration, extensive agricultural activities, plastics, the environment is being contaminated rapidly through soil, air, water. There are variety approaches treating toxins, but each its own set restrictions. As result, various therapies accessible, that effective, long-lasting, less harmful, have superior outcome extensively demanded. Modern research advances focus more on polymer-based nanoparticles, which frequently used in drug design, delivery systems, remediation, power storage, transformations, other fields. Bioinorganic nanomaterials could be better candidate to control contaminants environment. In this article, we focused their synthesis, characterization, photocatalytic process, contributions remediation against numerous ecological hazards. review also tried explore recent advancements futuristic prevent pollutants

Language: Английский

---

Revisiting the Therapeutic Effects of Essential Oils on the Oral Microbiome

Pharmacy, Journal Year: 2023, Volume and Issue: 11(1), P. 33 - 33

Published: Feb. 10, 2023

The extensive use of antibiotics has resulted in the development drug-resistant bacteria, leading to a decline efficacy traditional antibiotic treatments. Essential oils (EOs) are phytopharmaceuticals, or plant-derived compounds, that possess beneficial properties such as anti-inflammatory, antibacterial, antimicrobial, antiviral, bacteriostatic, and bactericidal effects. In this review, we present scientific findings on activity EOs an alternative therapy for common oral diseases. This narrative review provides deeper understanding medicinal their application dentistry. It not only evaluates effectiveness these antibacterial agents against bacteria but also covers general information composition, methods extraction, potential toxicity. Further nonclinical clinical studies must be conducted determine safety treating

Language: Английский

---

The Burden of Antimicrobial Resistance in Zambia, a Sub-Saharan African Country: A One Health Review of the Current Situation, Risk Factors, and Solutions

Pharmacology &amp Pharmacy, Journal Year: 2024, Volume and Issue: 15(12), P. 403 - 465

Published: Jan. 1, 2024

Language: Английский

---

Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review

Oxidative Medicine and Cellular Longevity, Journal Year: 2022, Volume and Issue: 2022, P. 1 - 20

Published: Aug. 26, 2022

Molecules with at least one unpaired electron in their outermost shell are known as free radicals. Free radical molecules produced either within our bodies or by external sources such ozone, cigarette smoking, X-rays, industrial chemicals, and air pollution. Disruption of normal cellular homeostasis redox signaling may result cardiovascular, neurodegenerative diseases cancer. Although ROS (reactive oxygen species) formed the GI tract, little is about how they contribute to pathophysiology disease etiology. When reactive species antioxidants imbalance bodies, can cause cell structure damage, diseases, diabetes, hypercholesterolemia, atherosclerosis, cancer, cardiovascular metabolic disorders, other obesity-related well protein misfolding, mitochondrial dysfunction, glial activation, subsequent apoptosis. Neuron cells gradually destroyed diseases. The production inappropriately aggregated proteins strongly linked oxidative stress. This review’s goal provide much information possible numerous illnesses possibilities multimodal neuroprotective therapy human illness, using already accessible medications demonstrating promise animal models, highlighted. Neuroprotection neurolongevity improve from use bioactive substances medicinal herbs like Allium stadium, Celastrus paniculatus, Centella asiatica. Many drugs’ role has been addressed. Preventing neuroinflammation demonstrated several models.

Language: Английский

---

Synthesis and characterization of silver nanoparticles developed using a novel lipopeptide(s) biosurfactant and evaluating its antimicrobial and cytotoxic efficacy.

Process Biochemistry, Journal Year: 2022, Volume and Issue: 124, P. 51 - 62

Published: Nov. 8, 2022

Language: Английский

---

Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products

Frontiers in Pharmacology, Journal Year: 2022, Volume and Issue: 13

Published: Sept. 8, 2022

Cancer is commonly thought to be the product of irregular cell division. According World Health Organization (WHO), cancer major cause death globally. Nature offers an abundant supply bioactive compounds with high therapeutic efficacy. Anticancer effects have been studied in a variety phytochemicals found nature. When Food and Drug Administration (FDA)-approved anticancer drugs are combined natural compounds, effectiveness improves. Several agents already progressed clinical trials based on these promising results against various forms. Natural prevent proliferation, development, metastasis by inducing cycle arrest, activating intrinsic extrinsic apoptosis pathways, generating reactive oxygen species (ROS), down-regulating activated signaling pathways. These chemicals known affect numerous important cellular such as NF-B, MAPK, Wnt, Notch, Akt, p53, AR, ER, many others, signals induce pre-cancerous or cells without harming normal cells. As result, non-toxic “natural drugs” taken from nature’s bounty could effective for prevention tumor progression and/or therapy human malignancies, either alone combination conventional treatments. also shown preclinical studies improve sensitivity resistant cancers currently available chemotherapy agents. To summarize, findings indicate that natural-sourced The vital purpose target pathways compounds.

Language: Английский

---

Herbal medicine: the magic way crouching microbial resistance

Natural Product Research, Journal Year: 2023, Volume and Issue: 37(24), P. 4280 - 4289

Published: Jan. 31, 2023

Bacterial resistance to antibiotics poses a high level of danger worldwide. mechanisms are spreading globally, impeding our ability treat common infectious diseases. Misuse and overuse accelerate microbial antibiotics. Despite the exerted efforts, none newly developed expected be effective against dangerous forms antibiotic-resistant bacteria. Since many plants have been shown contain powerful antimicrobial compounds that can act synergistically or alternatively antibiotics, demand for herbal medicines has recently increased co-treat microbes resistant Maximum benefit achieved when pharmacokinetics pharmacodynamics natural products match antibiotic. This review article refers nine highly key herbs use alongside overcome crises antibiotic resistance. Their unique molecular action highlighted.

Language: Английский

---

Response surface methodology for optimization of operational parameters to remove tetracycline from contaminated water by new magnetic Ho2MoO6/Fe2O3 nano adsorbent

Results in Engineering, Journal Year: 2024, Volume and Issue: 21, P. 101746 - 101746

Published: Jan. 12, 2024

World-wide, tetracycline is among the most commonly used and produced antibiotics. The entry of these chemicals into domestic sewage can result in water pollution. purpose this study to evaluate a new nano-adsorbent for separating from aquatic environments. Lab-scale batch experiments were conducted. Tetracycline removal parameters, such as temperature, adsorbent amount, initial concentration antibiotic, well contact time, investigated. Using Response Surface Methodology (Central Composite Design), effective parameters optimized appropriate model was developed predicting removal. We determined structure morphological properties nano absorbents by using Fourier transform infrared (FT-IR), X-ray powder diffraction (XRD), field emission scanning electron microscope (FE-SEM), transmission (TEM), vibrating sample magnetometer (VSM), diffuse reflectance spectroscopy (DRS) Brunauer-Emmett-Teller (BET) analysis. Data obtained practical tests compared with Langmuir Freundlich isotherms. Furthermore, adsorption kinetics studied. Results showed that best absorption, which equal 99.96 %, occurred at 30 °C, 1000 mg per liter, 20 90 min incubation. According RSM, quadratic equation calculate separation R2 = 0.9931. results studies related isotherms demonstrate process follows pseudo-second-order high ability nanocomposite absorb its ease due magnetic make an ideal choice removing water.

Language: Английский

---

Addressing Emerging Antibiotic Resistance Patterns: Implications for Public Health and Treatment Strategies

Indian Journal of Respiratory Care, Journal Year: 2025, Volume and Issue: 13(4), P. 270 - 270

Published: Feb. 17, 2025

Language: Английский

---

Pollution by Antimicrobials and Antibiotic Resistance Genes in East Africa: Occurrence, Sources, and Potential Environmental Implications

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101969 - 101969

Published: Feb. 22, 2025

Language: Английский

---