Therapeutic Benefits and Dietary Restrictions of Fiber Intake: A State of the Art Review

Nutrients, Journal Year: 2022, Volume and Issue: 14(13), P. 2641 - 2641

Published: June 26, 2022

Throughout history, malnutrition and deficiency diseases have been a problem for our planet's population. A balanced diet significantly influences everyone's health, fiber intake appears to play more important role than previously thought. The natural dietary fibers are category of carbohydrates in the constitution plants that not completely digested human intestine. High-fiber foods, such as fruits, vegetables whole grains, consistently highly beneficial health effectively reduced risk disease. Although mode action consumer body is fully understood, nutritionists professionals unanimously recognize therapeutic benefits. This paper presents consumption different countries, metabolism range benefits associated with intake. In addition, influence on intestinal microbiome, metabolic (obesity diabetes), neurological aspects, cardiovascular diseases, autoimmune cancer prevention discussed. Finally, restrictions excess addressed, which can cause episodes diarrhea dehydration increase likelihood bloating flatulence or even bowel obstruction. However, extensive studies needed regarding composition required amount relation saprotrophic microorganisms from enteral level various pathologies they be correlated.

Language: Английский

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Botanical Origin, Phytochemical Profile, and Antioxidant Activity of Bee Pollen from the Mila Region, Algeria

Antioxidants, Journal Year: 2025, Volume and Issue: 14(3), P. 291 - 291

Published: Feb. 28, 2025

Bee pollen is a complex mixture of floral pollen, and nectar fused substances from bee saliva. It well known for its high content proteins, carbohydrates, lipids, vitamins, phenolic compounds, among various other physiologically active components. Its composition varies significantly depending on botanical sources environmental conditions. This study investigates the relationship between origins, chemical compositions, antioxidant activities 15 samples collected different areas in Mila region northeastern Algeria. The origins were identified using palynological method, categorizing 11 as monofloral rest polyfloral. total flavonoid contents measured, their capacities evaluated through DPPH radical scavenging assay, reducing power assay (FRAP), capacity (TAC). HPLC analysis was conducted to measure 17 compounds. data indicated that (TPC) (TFC) ranged 7.72 ± 0.29 23.49 1.48 mg GAE/g 0.00 5.57 0.27 QE/g respectively. variations concentration bioactive compounds led significant differences activities: (IC50: 1.12 0.15 0.21 mg/mL), FRAP (EC50: 0.06 TAC (262.17 3.41 677.14 12.81 EAA mg/100 g pollen), with most being types Cistus type Brassica type. A strong correlation observed TPC, TFC, activity. Among tested only coumaric acid, rutin, myricetin, naringenin, resveratrol, kaempferol detected. In conclusion, both polyfloral represent rich source polyphenols potential.

Language: Английский

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Bee Pollen: Clinical Trials and Patent Applications

Nutrients, Journal Year: 2022, Volume and Issue: 14(14), P. 2858 - 2858

Published: July 12, 2022

Bee pollen is a natural cocktail of floral nectar, flower pollen, enzymes, and salivary secretions produced by honeybees. one the bee products most enriched in proteins, polysaccharides, polyphenols, lipids, minerals, vitamins. It has significant health medicinal impact provides protection against many diseases, including diabetes, cancer, infectious, cardiovascular. commonly promoted as cost-effective functional food. In particular, been applied clinical trials for allergies prostate illnesses, with few investigations on cancer skin problems. However, it involved several patents recipes to combat chronic This review aimed highlight involving different cases present role supplementary food potential product cosmetic applications.

Language: Английский

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Increasing Bioavailability of Trans-Ferulic Acid by Encapsulation in Functionalized Mesoporous Silica

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(2), P. 660 - 660

Published: Feb. 16, 2023

Two types of mesoporous materials, MCM-41 and MCM-48, were functionalized by the soft-template method using (3-aminopropyl)triethoxysilane (APTES) as a modifying agent. The obtained silica materials loaded with trans-ferulic acid (FA). In order to establish morphology structure series specific techniques used such as: X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Brunauer-Emmet-Teller (BET), Fourier Transform Infrared Spectroscopy (FTIR) thermogravimetric analysis (TGA). We monitored in vitro release FA at two different pH values, simulated gastric fluid (SGF) intestinal (SIF). Additionally, Staphylococcus aureus ATCC 25923, Escherichia coli 25922, Pseudomonas aeruginosa 27853 Candida albicans 10231 evaluate antimicrobial activity materials. conclusion can be employed controlled systems for polyphenols extracted from natural sources.

Language: Английский

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Bee Bread: A Promising Source of Bioactive Compounds with Antioxidant Properties—First Report on Some Antimicrobial Features

Antioxidants, Journal Year: 2024, Volume and Issue: 13(3), P. 353 - 353

Published: March 15, 2024

Bee bread has received attention due to its high nutritional value, especially phenolic composition, which enhances life quality. The present study aimed evaluate the chemical and antimicrobial properties of bee (BB) samples from Romania. Initially, alcoholic extracts (BBEs) were obtained BB collected prepared by Apis mellifera carpatica bees. composition BBE was characterized Fourier Transform Infrared Spectroscopy (FTIR) total phenols flavonoid contents determined. Also, a UHPLC-DAD-ESI/MS analysis compounds (PCs) antioxidant activity evaluated. Furthermore, BBEs evaluated qualitative quantitative assessments. BBs studied in this paper are provided 31 families plant species, with content varying between 7.10 18.30 mg gallic acid equivalents/g 0.45 1.86 quercetin BB, respectively. Chromatographic revealed these had significant compounds, flavonoids much higher quantities than acids. All presented against all clinical standard pathogenic strains tested. Salmonella typhi, Candida glabrata, albicans, kefyr most sensitive, while BBEs’ antifungal on C. krusei not investigated any prior research. In addition, reports inhibitory microbial (bacterial fungi) adhesion capacity inert substratum for first time.

Language: Английский

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Translational Research on Bee Pollen as a Source of Nutrients: A Scoping Review from Bench to Real World

Nutrients, Journal Year: 2023, Volume and Issue: 15(10), P. 2413 - 2413

Published: May 22, 2023

The emphasis on healthy nutrition is gaining a forefront place in current biomedical sciences. Nutritional deficiencies and imbalances have been widely demonstrated to be involved the genesis development of many world-scale public health burdens, such as metabolic cardiovascular diseases. In recent years, bee pollen emerging scientifically validated candidate, which can help diminish conditions through nutritional interventions. This matrix being extensively studied, has proven very rich well-balanced nutrient pool. this work, we reviewed available evidence interest source. We mainly focused richness nutrients its possible roles main pathophysiological processes that are directly linked imbalances. scoping review analyzed scientific works published last four focusing clearest inferences perspectives translate cumulated experimental preclinical into clinically relevant insights. promising uses for malnutrition, digestive health, disorders, other bioactivities could helpful readjust homeostasis (as it also true case anti-inflammatory or anti-oxidant needs), well benefits diseases, were identified. knowledge gaps identified, along with practical challenges hinder establishment fructification these uses. A complete data collection made major range botanical species allows more robust clinical information.

Language: Английский

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Resistance, Tolerance, Virulence and Bacterial Pathogen Fitness—Current State and Envisioned Solutions for the Near Future

Pathogens, Journal Year: 2023, Volume and Issue: 12(5), P. 746 - 746

Published: May 22, 2023

The current antibiotic crisis and the global phenomena of bacterial resistance, inherited non-inherited, tolerance—associated with biofilm formation—are prompting dire predictions a post-antibiotic era in near future. These refer to increases morbidity mortality rates as consequence infections multidrug-resistant or pandrug-resistant microbial strains. In this context, we aimed highlight status resistance phenomenon significance virulence properties/fitness for human health review main strategies alternative complementary therapy, some them being already clinically applied clinical trials, others only foreseen research phase.

Language: Английский

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Antibacterial Effect of Gallic Acid in UV-C Light Treatment Against Escherichia coli O157:H7 and the Underlying Mechanism

Food and Bioprocess Technology, Journal Year: 2023, Volume and Issue: 17(8), P. 2216 - 2231

Published: Nov. 14, 2023

Language: Английский

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Biochemical properties of different Algerian bee pollen samples

Mediterranean Journal of Nutrition and Metabolism, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Background Bee pollen is a hive derived product formed from the agglomeration of flower pollen, nectar and bee saliva. It's hailed for its potential health benefits such as antioxidant, antibacterial anti-inflammatory effect. Objective The present work aims to assess Algerian quality by highlighting their phenolic composition, antimicrobial, enzymatic antiviral activities, in addition wound healing Deoxyribonucleic acid (DNA) protection Methods In this study, fourteen 70% ethanol extracts samples were analyzed determine profils biological activities. Thus, Reversed-phase high-performance liquid chromatography with Ultraviolet Detection RP-HPLC-UV done, antibacterial, enzymatic, healing, DNA anti-Herpes Simplex Virus 1 (anti- HSV-1) tests are carried out. Results showed good antioxidant activity, variation selective activity against Gram negative bacteria strains (Escherichia coli “E.coli”, Salmonella typhimurium Yersinia pestis), inhibition acetylcholinesterase α-glucosidase activation Superoxide Dismutase (SOD). P4, P7, P8 P14 show high while P6 P10 have Only P7 anti-HSV-1 activity. Conclusion different activities varied according phytochemical composition each sample not harvest region. That confirmed Principal Component Analysis (PCA) correlations relationships between bioactive compounds where it can be seen that grouped region harvest.

Language: Английский

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Antioxidant-Rich Polyfloral Bee Pollen Exerts Antimicrobial Activity and Anti-Inflammatory Effect in A549 Lung Epithelial Cells by Modulating the NF-κB Pathway

Foods, Journal Year: 2025, Volume and Issue: 14(5), P. 802 - 802

Published: Feb. 26, 2025

Bee pollen is produced by honeybees from the agglutination of grains belonging to one or more plant species. Although it intended be a nutritional source for hive, its remarkable concentration nutrients and phytochemicals, combined with pleasant organoleptic qualities, makes appealing human consumption. This study examined phytochemical content antioxidant antimicrobial activities polyfloral bee collected in Tuscany (Italy). Additionally, less studied anti-inflammatory potential towards tumor necrosis factor-alpha (TNF-α)-inflamed A549 cells was evaluated assess possible use inflammatory respiratory diseases. extract (BPE) chemically characterized terms total polyphenol (20.2 ± 1.5 mg gallic acid equivalents/g fw), flavonoid (9.22 0.64 quercetin carotenoid (10.4 1.4 µg carotenoids/g fw) contents. BPE exerted good antiradical ferric reducing power (38.6 4.5 Fe2+/g oxygen radical absorbance capacity (433.77 18.95 μmol TE/g 2,2-diphenyl-1-picrylhydrazyl (EC50 = 613.8 79.2 μg/mL) assays. inhibited growth Bacillus subtilis Pseudomonas stutzeri (MIC 10 mg/mL) microdilution assay. When TNF-α-inflamed were pretreated (10 50 µg/mL), upregulated interleukin-8 gene cyclooxygenase-2 protein expression significantly attenuated. modulated nuclear factor-κB signaling pathway decreasing active phosphorylated form levels. These encouraging results confirm that honeybee valuable health-promoting food could alleviate component various chronic pulmonary conditions.

Language: Английский

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