The Comparison of the Profile of Phenolic Compounds in Noni (Morinda citrifolia L.) Fruit by Different Drying Methods DOI Creative Commons

Qianxin Li,

J Y Chai,

Su Deng

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(8), P. 1398 - 1398

Published: April 17, 2025

In this study, the compositional shifts in free and bound phenolic compounds of Morinda citrifolia L. (Noni) processed by different drying methods were investigated. Twenty-seven compounds, predominantly rutin quinic acid, discovered fresh Noni fruit. Vacuum freeze-drying retained highest content, with (1809.83 mg/kg DW) acid (198.72 as primary constituents, while phenolics dominated benzoic (35.56 DW). Hot-air reduced 51.59% (80% methanol) (base hydrolysis) 35.55%, a significant degradation acid. Microwave similarly decreased phenolics, though caffeic increased to 46.45 DW due thermal stability. Bound showed content (alkaline fruits, primarily (220.67 (77.02 DW), surpassing acid/enzyme methods. While vacuum effectively preserved (hot-air/microwave drying) promoted release quercetin (free phenols) 3,4-dihydroxybenzoic (bound phenols). The findings study elucidate species-specific dynamics under regimes, providing quantitative guidelines for advancing understanding underlying health-promoting phytochemical profiles Noni.

Language: Английский

Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health DOI
Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Language: Английский

Citations

7
Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review DOI Creative Commons
Maroua Jalouli, Md. Ataur Rahman, Partha Biswas

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 24, 2025

Polyphenols, naturally occurring phytonutrients found in plant-based foods, have attracted significant attention for their potential therapeutic effects neurological diseases and neuroinflammation. These compounds possess diverse neuroprotective capabilities, including antioxidant, anti-inflammatory, anti-amyloid properties, which contribute to mitigating the progression of neurodegenerative conditions such as Alzheimer's Disease (AD), Parkinson's (PD), Dementia, Multiple Sclerosis (MS), Stroke, Huntington's (HD). Polyphenols been extensively studied ability regulate inflammatory responses by modulating activity pro-inflammatory genes influencing signal transduction pathways, thereby reducing neuroinflammation neuronal death. Additionally, polyphenols shown promise various cellular signaling pathways associated with viability, synaptic plasticity, cognitive function. Epidemiological clinical studies highlight polyphenol-rich diets decrease risk alleviate symptoms disorders Furthermore, demonstrated through regulation key Akt, Nrf2, STAT, MAPK, play critical roles neuroprotection body's immune response. This review emphasizes growing body evidence supporting combating neurodegeneration neuroinflammation, well enhancing brain health. Despite substantial promising hypotheses, further research investigations are necessary fully understand role establish them advanced targets age-related neuroinflammatory conditions.

Language: Английский

Citations

3
The Role of Dietary Antioxidants, Food Supplements and Functional Foods for Energy Enhancement in Healthcare Professionals DOI Creative Commons

Theodora Kalogerakou,

Μαρία Αντωνιάδου

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1508 - 1508

Published: Dec. 10, 2024

Healthcare professionals frequently experience significant work overload, which often leads to substantial physical and psychological stress. This stress is closely linked increased oxidative a corresponding decline in energy levels. scoping review investigates the potential impact of dietary antioxidants food supplements conjunction with diet controlling these negative effects. Through an analysis biochemical pathways involved metabolism, paper emphasizes effectiveness targeted interventions. Key antioxidants, such as vitamins C E, polyphenols, carotenoids, are evaluated for their ability counteract enhance Additionally, assesses various supplements, including omega-3 fatty acids, coenzyme Q10, ginseng, mechanisms action enhancement. Practical guidelines incorporating energy-boost strategies into routine healthcare provided, emphasizing importance modifications reducing improving overall well-being performance high-stress environments. The concludes by suggesting directions future research validate findings explore new interventions that may further support under overload.

Language: Английский

Citations

5
The Release of Bound Phenolics to Enhance the Antioxidant Activity of Cornmeal by Liquid Fermentation with Bacillus subtilis DOI Creative Commons
Ping Zhang, Jialan Zhang, Li Li

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 499 - 499

Published: Feb. 4, 2025

This study investigated the influence of Bacillus subtilis fermentation on composition phenolic substances and antioxidant activity in cornmeal. The results indicate that process significantly increased both total content (TPC) flavonoid (TFC). After 5 days fermentation, TPC rose from 31.68 ± 1.72 mg/g to 39.46 2.95 mg/g, representing a 24.56% increase, while TFC 2.13 0.11 7.56 0.29 marking 254.93% increase. Additionally, proportion free compounds cornmeal 20.24% 83.98%, bound decreased 79.76% 16.02%. Furthermore, hydrolytic enzyme activities cellulase, β-glucosidase, xylanase were correlated with (FPC) (r > 0.85, p < 0.05), indicating their crucial role releasing Employing scanning electron microscopy, differential calorimetry, X-ray diffraction, Fourier-transform infrared spectroscopy analyses, we inferred enzymes produced by microorganisms disrupted cellular structure weakened interactions between phenolics food matrix, thereby facilitating release compounds. resulted an overall increase provided novel approach enhancing bioavailability acids cornmeal, potential benefits processing.

Language: Английский

Citations

0
Unveiling roles of beneficial gut bacteria and optimal diets for health DOI Creative Commons
Thallapuranam Krishnaswamy Suresh Kumar, Riya Mukherjee, Pratibha Gaur

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 18, 2025

The gut microbiome plays a pivotal role in human health, influencing digestion, immunity, and disease prevention. Beneficial bacteria such as Akkermansia muciniphila, Adlercreutzia equolifaciens, Christensenella minuta contribute to metabolic regulation immune support through bioactive metabolites like short-chain fatty acids (SCFAs). Dietary patterns rich prebiotics, fermented foods, plant-based compounds, including polyphenols flavonoids, promote diversity stability. However, challenges individual variability, bioavailability, dietary adherence, the dynamic nature of microbiota remain significant. This review synthesizes current insights into bacteria's emphasizing mechanisms by which interventions modulate microbiota. Additionally, it highlights advancements microbiome-targeted therapies transformative potential personalized nutrition, leveraging profiling artificial intelligence (AI) develop tailored strategies for optimizing health mitigating chronic inflammatory disorders. Addressing these requires multidisciplinary approach that integrates scientific innovation, ethical frameworks, practical implementation strategies.

Language: Английский

Citations

0
Prebiotic potential of enzymatically modified lingonberry polyphenols DOI Creative Commons
Diana Karcheva‐Bahchevanska, Niko Benbassat, M Nikolova

et al.

Pharmacia, Journal Year: 2025, Volume and Issue: 72, P. 1 - 8

Published: March 27, 2025

In the present study, enzymatic glycosylation of polyphenolic compounds obtained from fruits Vaccinium vitis-idaea L. (lingonberries) was performed. The individual components were identified by HPTLC and HPLC analysis. Fructosyltransferase – levansucrase L17 (FTF) used for purposes. To investigate prebiotic potential glycosylated polyphenols, metabolic profile probiotic strain Lactobacillus plantarum L10 monitored in presence lyophilized lingonberry extract at concentrations ranging 0.1 to 0.5%. An increase lactate acetate concentration observed among organic acids studied. values increased 18% 33% lyophilizate 0.1% 0.5%, respectively. same trend acetate, 13% 18%. Enzymatically modified polyphenols are very promising as prebiotics due their ability selectively modulate gut microbiota short-chain fatty (SCFAs) production, which is associated with improved human intestinal systemic health.

Language: Английский

Citations

0
The Comparison of the Profile of Phenolic Compounds in Noni (Morinda citrifolia L.) Fruit by Different Drying Methods DOI Creative Commons

Qianxin Li,

J Y Chai,

Su Deng

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(8), P. 1398 - 1398

Published: April 17, 2025

In this study, the compositional shifts in free and bound phenolic compounds of Morinda citrifolia L. (Noni) processed by different drying methods were investigated. Twenty-seven compounds, predominantly rutin quinic acid, discovered fresh Noni fruit. Vacuum freeze-drying retained highest content, with (1809.83 mg/kg DW) acid (198.72 as primary constituents, while phenolics dominated benzoic (35.56 DW). Hot-air reduced 51.59% (80% methanol) (base hydrolysis) 35.55%, a significant degradation acid. Microwave similarly decreased phenolics, though caffeic increased to 46.45 DW due thermal stability. Bound showed content (alkaline fruits, primarily (220.67 (77.02 DW), surpassing acid/enzyme methods. While vacuum effectively preserved (hot-air/microwave drying) promoted release quercetin (free phenols) 3,4-dihydroxybenzoic (bound phenols). The findings study elucidate species-specific dynamics under regimes, providing quantitative guidelines for advancing understanding underlying health-promoting phytochemical profiles Noni.

Language: Английский

Citations

0