Phytomedicine,
Journal Year:
2024,
Volume and Issue:
133, P. 155900 - 155900
Published: Aug. 1, 2024
Although
blood
flow
is
restored
after
treatment
of
myocardial
infarction
(MI),
ischemia
and
reperfusion
(I/R)
can
cause
cardiac
injury,
which
a
leading
heart
failure.
Gastrodin
(GAS)
exerts
protective
effects
against
brain,
heart,
kidney
I/R.
However,
its
pharmacological
mechanism
in
I/R
injury
(MIRI)
remains
unclear.
GAS
regulates
autophagy
various
diseases,
such
as
acute
hepatitis,
vascular
dementia,
stroke.
We
hypothesized
that
could
repair
mitochondrial
damage
regulate
to
protect
MIRI.
Male
C57BL/6
mice
H9C2
cells
were
subjected
hypoxia-reoxygenation
(H/R)
administration,
respectively,
assess
the
impact
on
cardiomyocyte
phenotypes,
structure
function.
The
effect
function
patients
undergoing
surgery
has
been
observed
clinical
practice.
function,
structure,
expression
related
molecules
an
animal
model
MIRI
evaluated
using
immunohistochemical
staining,
enzyme-linked
immunosorbent
assay
(ELISA),
transmission
electron
microscopy,
western
blotting,
gene
sequencing.
Its
morphological,
molecular,
functional
phenotypes
cardiomyocytes
H/R
real-time
quantitative
PCR,
blotting.
significantly
reduces
infarct
size
improves
models
increases
viability
cellular
models.
In
practice,
was
alleviated
with
better
application
GAS;
improvements
mitochondria
activation
also
observed.
primarily
cardioprotective
through
PINK1/Parkin
pathway,
promotes
clear
damaged
mitochondria.
promote
mitophagy
preserve
PINK1/Parkin,
thus
indicating
tremendous
potential
effective
perioperative
agent.
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(10), P. 1530 - 1530
Published: Sept. 27, 2021
The
antioxidant
activity
(AA),
total
phenolic
content
(TPC),
and
flavonoid
(TFC)
of
selected
Indonesian
Zingiberaceae
herbs
were
determined.
An
optimization
extraction
procedure
was
conducted
by
using
Taguchi
L16
orthogonal
array.
Four
chemical
assays
applied,
including
2,2-diphenyl-2-picrylhydrazyl
(DPPH)
radical
scavenging
assay,
H2O2
Folin-Ciocalteau
(F-C)
NaNO2-AlCl3-NaOH
which
revealed
remarkable
differences
in
AA,
TPC,
TFC.
result
indicated
the
diversity
AA
composition
among
herbs,
C.
longa
exhibited
highest
AA.
HPLC-PAD
analysis
that
curcumin
present
five
high
amount
longa.
Pearson
correlation
identified
TPC
TFC
significant
contributors
to
likely
main
contributing
compound.
Our
approach
concluded
is
greatest
source
natural
antioxidants
12
indigenous
herbs.
use
a
mixed-method
augment
findings
solitary
methods
might
facilitate
future
researchers
uncover
deeper
hidden
meanings.
Forests,
Journal Year:
2021,
Volume and Issue:
12(5), P. 648 - 648
Published: May 20, 2021
Cinnamon
is
an
unusual
tropical
plant
belonging
to
the
Lauraceae
family.
It
has
been
used
for
hundreds
of
years
as
a
flavor
additive,
but
it
also
in
natural
Eastern
medicine.
extracts
are
vital
oils
that
contain
biologically
active
compounds,
such
cinnamon
aldehyde,
cinnamic
alcohol,
acid,
and
cinnamate.
antioxidant,
anti-inflammatory,
antibacterial
properties
treat
diseases
diabetes
cardiovascular
disease.
In
folk
medicine,
species
have
medicine
respiratory
digestive
disorders.
Their
potential
prophylactic
therapeutic
use
Parkinson’s
Alzheimer’s
disease
discovered.
This
review
summarizes
available
isolation
methods
analytical
techniques
identify
compounds
present
bark
leaves
influence
these
treatment
Biomedicine & Pharmacotherapy,
Journal Year:
2021,
Volume and Issue:
146, P. 112514 - 112514
Published: Dec. 25, 2021
Cancer
retains
a
central
place
in
fatality
rates
among
the
wide
variety
of
diseases
known
world
over,
and
conventional
synthetic
medicaments,
albeit
used
until
now,
produce
numerous
side
effects.
As
result,
newer,
better,
safer
alternatives
such
as
natural
plant
products,
are
gravely
required.
Essential
oils
(EOs)
offer
plethora
bioactivities
including
antibacterial,
antiviral,
antioxidant,
anticancer
properties,
therefore,
use
EOs
combination
with
drugs
or
aromatherapy
continues
to
be
popular
many
settings.
In
view
paramount
importance
their
potential
bioactivities,
this
review
summarizes
current
knowledge
on
interconnection
between
cancer
treatment.
particular,
presents
an
updated
summary
chemical
composition
EOs,
applications
treatments
based
clinical
studies,
mechanism
action
against
cell
lines.
Similarly,
overview
using
enhancing
immunity
during
treatment
is
provided.
Further,
focuses
recent
technological
advancements
loading
protein
microspheres,
ligands,
nanoemulsions/nanoencapsulation,
which
multiple
benefits
via
site-specific
target-oriented
delivery
drugs.
The
continuing
studies
implicate
that
pharmacological
rewarding
research
area.
International Journal of Microbiology,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 7
Published: March 23, 2022
Edible
mushrooms
are
fungi
that
can
be
seen
with
the
naked
eye
and
relatively
easy
to
gather
by
hand.
This
review
article
highlights
health
benefit
biochemistry
of
several
mushroom
species.
Advanced Engineering Materials,
Journal Year:
2022,
Volume and Issue:
24(6)
Published: April 5, 2022
Since
ancient
times,
wound
dressings
have
experienced
many
significant
improvements.
Evolution
began
using
natural
materials
to
merely
cover
wounds
and
advanced
used
innovative
techniques
that
can
be
customized
perform
different
impressive
functions.
Recent
dressings,
which
are
made
of
electrospun
polymers,
contain
active
compounds,
such
as
antimicrobial
agents,
aid
in
healing
prevent
dehydration
infection.
The
mentioned
issues
may
influence
the
process,
leading
even
serious
health
risks
for
patients.
As
a
result,
scientists
now
working
on
novel
bandages
with
improved
properties.
Electrospun
polymeric
nanofibers,
because
their
structural
similarities
normal
skin's
extracellular
matrix
(ECM),
bactericidal
activity,
appropriateness
distribute
bioactive
molecules
location,
regarded
good
resources
enhancing
skin
regeneration
controlling
Herein,
latest
findings
approaches
producing
nanofibers
electrospinning
related
processes
discussed.
advances
antibacterial
biopolymeric
incorporating
nanoparticles
(silver,
zinc
oxide,
copper
etc.)
This
review
paper
raise
issues,
encourage
additional
research,
offer
important
insight
into
potential
area
fibers.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(4), P. 787 - 787
Published: March 23, 2023
Natural-based
biomaterials
play
an
important
role
in
developing
new
products
for
medical
applications,
primarily
cutaneous
injuries.
A
large
panel
of
with
antioxidant
properties
has
revealed
advancement
supporting
and
expediting
tissue
regeneration.
However,
their
low
bioavailability
preventing
cellular
oxidative
stress
through
the
delivery
system
limits
therapeutic
activity
at
injury
site.
The
integration
compounds
implanted
biomaterial
should
be
able
to
maintain
while
facilitating
skin
recovery.
This
review
summarises
recent
literature
that
reported
natural
antioxidant-incorporated
promoting
wound
healing
regeneration,
which
is
supported
by
evidence
from
vitro,
vivo,
clinical
studies.
Antioxidant-based
therapies
have
shown
promising
numerous
animal
studies,
even
though
studies
remain
very
limited.
We
also
described
underlying
mechanism
reactive
oxygen
species
(ROS)
generation
provided
a
comprehensive
ROS-scavenging
found
last
six
years.
Veterinary World,
Journal Year:
2023,
Volume and Issue:
unknown, P. 369 - 379
Published: Feb. 25, 2023
Poultry
is
one
of
the
most
consumed
sources
animal
protein
around
world.
To
meet
global
demands
for
poultry
meat
and
eggs,
it
necessary
to
improve
their
nutrition
sustain
industry.
However,
industry
faces
several
challenges,
including
feedstuff
availability,
banning
antibiotics
as
growth
promoters,
environmental
stressors.
Therefore,
there
a
critical
need
include
available
nutraceuticals
in
diet
Nutraceuticals
are
natural
chemical
substances
that
positively
influence
physiological
productive
traits.
Botanical
products
(such
fenugreek
seeds,
ginger
roots,
olive
leaves)
among
commonly
used
gradually
gaining
popularity
due
immense
benefits
therapeutic
properties.
They
can
be
added
separately
or
combination
(as
antioxidant
immunostimulant)
health
production.
rich
essential
oils
fatty
acids,
which
have
multiple
on
animal's
digestive
system,
such
activating
enzymes
restoring
microbiota
balance,
enhancing
health,
These
been
shown
stimulate
expression
genes
related
growth,
metabolism,
immunity.
In
addition,
oil
supplementation
diets
up-regulated
some
crucial
associated
with
nutrient
transportation
glucose
transporter-2
sodium-glucose
cotransporter-1).
Previous
studies
suggested
botanical
compounds
increased
broiler
body
weight
hen
egg
production
by
approximately
7%
15%,
respectively.
Furthermore,
enhanced
reproductive
efficiency
hens
semen
quality
roosters
13%.
This
review
article
discusses
significant
effects
how
they
benefit
poultry,
especially
light
ban
promoters.
The
burden
of
foodborne
diseases
and
their
associated
illness/death
is
a
global
concern.
Hazard
analysis
critical
control
points
(HACCP)
food
safety/quality
management
are
employed
to
combat
this
problem.
With
the
existing
emerging
concerns,
study
aims
evaluate
traditional
modern/novel
approach
improving
HACCP,
safety,
quality
in
agricultural
systems.
modern
innovations
safety
were
integrated
into
HACCP
system,
including
its
principles,
applications,
steps,
plans,
standards,
etc.,
as
well
factors
management,
for
improved
food,
agricultural,
pharmaceutical
industries.
identified
many
responsible
contamination,
chemical
contaminants,
such
allergens,
histamine,
cyanogenic
glycosides,
mycotoxins,
toxic
elements,
biological
Campylobacter,
Brucella,
viruses,
Escherichia
coli,
prions,
Staphylococcus
aureus,
Listeria
monocytogenes,
protozoa,
parasitic
pathogens,
physical
bone,
glass,
metal,
personal
effects,
plastic,
stones,
wood,
etc.
results
present
descriptive
preliminary
safe
handling
procedures,
ISO
22000,
Water
labelling,
with
recent
developments
ensure
management.
also
technologies
light
technologies,
artificial
intelligence
(AI),
novel
freezing
(isochoric
freezing),
automation,
software
easy
detection
contaminants.
all
these
understanding
development,
domestic,
industries
can
be
position
products.
