Bioengineering, Journal Year: 2023, Volume and Issue: 10(5), P. 613 - 613
Published: May 19, 2023
As the global health care system grapples with steadily rising costs, increasing numbers of admissions, and chronic defection doctors nurses from profession, appropriate measures need to be put in place reverse this course before it is too late [...].
Language: Английский
Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: 21(11), P. 1573 - 1594
Published: May 29, 2024
Chronic wounds require more sophisticated care than standard wound because they are becoming severe as a result of diseases like diabetes. By resolving shortcomings in existing methods, 3D-bioprinting offers viable path toward personalized, mechanically strong, and cell-stimulating dressings.
Language: Английский
Citations
4
Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 797 - 797
Published: June 17, 2024
To create a review of the published scientific literature on benefits and potential perspectives use 3D bio-nitrification in field pharmaceutics. This work was performed accordance with Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) guidelines reporting meta-analyses systematic reviews. The databases PubMed, Scopus, Google Scholar, ScienceDirect were used to search extract data using following keywords: bioprinting, drug research development, personalized medicine, pharmaceutical companies, clinical trials, testing. points several aspects application bioprinting pharmaceutics reviewed. main applications are development new molecules as well preparation drugs, but greatest terms screening Growth printing has facilitated applications, enabling delivery systems individual patients. Bioprinting presents opportunity print drugs demand according needs patient, making shape, structure, dosage suitable each patient’s physical conditions, i.e., specific controlled release rates; porous tablets reduce swallowing difficulties; make transdermal microneedle patches patient pain; so on. On other hand, can precisely control distribution cells biomaterials build organoids, or an Organ-on-a-Chip, testing printed organs mimicking specified disease characteristics instead animal trials. offer customized platforms meeting range individualized needs, prospects at different stages therapy. role preclinical is also significant importance shortening time launch medicinal product market.
Language: Английский
Citations
4
European Polymer Journal, Journal Year: 2024, Volume and Issue: 217, P. 113210 - 113210
Published: July 18, 2024
Language: Английский
Citations
4
Pakistan BioMedical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 02 - 10
Published: Jan. 31, 2025
Cartilage repair is a major clinical problem because of the poor intrinsic healing capacity cartilage coupled with limitations conventional therapies and synthetic substitutes. These challenges have been pursued by bioprinting, which technique that can generate scaffolds mimic native cartilage. This review aims to discuss current future development bioprinting for tissue regeneration focus on most common biomaterials such as alginate, gelatin, collagen, along emerging materials smart hydrogels, nanomaterials, bioactive molecules. The also outlines other technologies like high resolution, 4D, hybrid, microfluidic assisted are believed improve mechanical properties, biological integration vascularization constructs produced through bioprinting. Some problems still unresolved those scale up, biocompatibility immune response hinders application bioprinted further concludes owing some regulatory issues lack an ideal practice in persists. prospects highlighted include use patient derived cells, artificial intelligence process optimization adaptive biomaterials. Mitigating these challenged integrated advanced will enable translation develop personalized, functional, durable constructs.
Language: Английский
Citations
0
Procedia Computer Science, Journal Year: 2025, Volume and Issue: 253, P. 1276 - 1282
Published: Jan. 1, 2025
Language: Английский
Citations
0
Patient-Oriented Medicine and Pharmacy, Journal Year: 2025, Volume and Issue: unknown
Published: March 7, 2025
Bioprinting has emerged as a groundbreaking technology in the realms of organ transplantation and regenerative medicine, addressing critical challenges such shortages tissue repair. This review explores technological advancements innovations bioprinting, highlighting state-of-the-art techniques, bioinks, applications engineering. Key milestones printing functional tissues, including vascularized transplantable prototypes, are discussed alongside role bioprinting personalized where patient-oriented models revolutionizing drug testing therapeutic strategies. Furthermore, this article examines ethical considerations associated with offering insights into its future potential to transform global healthcare.
Language: Английский
Citations
0
Journal of Biomechanics, Journal Year: 2025, Volume and Issue: 184, P. 112677 - 112677
Published: April 6, 2025
Root-analog implants are frequently fabricated from titanium, which can be associated with various problems, e.g. hypersensitivity to titanium. In this study, we evaluate the bending moments of different polyetheretherketone-based root analog as a metal-free alternative. For this, an extracted tooth 31 and 36 was scanned create STL data set each tooth. These were used fabricate n = 8 per group, 5 groups being type. Two additively manufactured using material extrusion. The other milled differnet polyetheretherketone grades. After artificial ageing, samples statically loaded until fracture in order determine moment. Of form 31, white, grade showed highest moment 2835.3 ± 509.8 Nmm unfilled, processed lowest. RAIs 36, 29342.6 854.7 lowest 19880.5 7188.6 Nmm. Basically, results between subtractively significantly different. terms mechanical requirements oral cavity, one-piece -based appear provide more predictable than ones. Taken together, our study suggests that solidly designed made molars able withstand cavity.
Language: Английский
Citations
0
Review of Scientific Instruments, Journal Year: 2025, Volume and Issue: 96(4)
Published: April 1, 2025
Soft material research has seen significant growth in recent years, with emerging applications robotics, electronics, and healthcare diagnostics where understanding the mechanical response is crucial for precision design. Traditional methods measuring nonlinear properties of soft materials require specially sized samples that are extracted from their natural environment to be mounted on testing instrument. This been shown compromise data accuracy various biological materials. To overcome this, Volume Controlled Cavity Expansion (VCCE) method was developed. technique tests by controlling formation rate a liquid cavity inside at tip an injection needle simultaneously resisting pressure describes response. Despite VCCE’s early successes, expansion its application beyond academia hindered cost, size, expertise. In first portable, benchtop instrument utilizing VCCE presented here. device, built affordable, readily available components open-source software, streamlines experimentation without sacrificing performance or precision. It especially suitable space-limited settings designed use non-experts, promoting widespread adoption. The instrument’s efficacy demonstrated through polydimethylsiloxane varying stiffness. study not only validates but also sets stage further advancements broader testing. All data, along acquisition, control, post-processing scripts, made GitHub.
Language: Английский
Citations
0
Brazilian Journal of Transplantation, Journal Year: 2025, Volume and Issue: 28(1)
Published: April 25, 2025
Background: Bioprinting has emerged as an innovative technology in organ transplantation and regenerative medicine, aiming to address pressing challenges such the shortage of donor organs need for effective tissue repair. By leveraging advanced 3D printing techniques, bioprinting enables fabrication functional tissues with precise architectural biological properties. Methods: This review provides in-depth analysis latest advancements bioprinting, focusing on cutting-edge development bioinks, their applications engineering. It examines significant breakthroughs creation vascularized transplantable prototypes explores role personalized medicine. Results: The findings highlight transformative impact biomedical field, particularly drug testing, therapeutic modeling, patient-specific treatment strategies. Additionally, key challenges—including technological limitations, ethical concerns, regulatory considerations—are discussed provide a comprehensive understanding field’s progress potential obstacles. Conclusion: holds immense promise revolutionizing global healthcare by offering solutions shortages advancing However, continued research innovation are necessary overcome existing facilitate its clinical translation into mainstream medical practice.
Language: Английский
Citations
0
Brazilian Journal of Transplantation, Journal Year: 2025, Volume and Issue: 28(1)
Published: April 25, 2025
Introdução: A bioimpressão despontou como uma tecnologia inovadora no transplante de órgãos e na medicina regenerativa, visando solucionar desafios urgentes, a escassez doadores necessidade reparo eficaz tecidos. Ao aproveitar as técnicas avançadas impressão 3D, permite fabricação tecidos funcionais com propriedades arquitetônicas biológicas precisas. Métodos: Esta revisão fornece análise detalhada dos últimos avanços em bioimpressão, concentrando-se ponta, desenvolvimento biotintas suas aplicações engenharia Ela examina os significativos criação protótipos vascularizados transplantáveis explora função da personalizada. Resultados: As descobertas destacam o impacto transformador campo biomédico, particularmente testes medicamentos, modelagem terapêutica estratégias tratamento específicas para paciente. Além disso, principais — incluindo limitações tecnológicas, preocupações éticas considerações regulatórias são discutidos fornecer compreensão abrangente do progresso possíveis obstáculos. Conclusão: é imensamente promissora revolucionar saúde global, oferecendo soluções avanço regenerativa. No entanto pesquisa inovação contínuas necessárias superar existentes facilitar sua tradução clínica prática médica convencional.
Citations
0