International Journal of Nanomedicine,
Journal Year:
2021,
Volume and Issue:
Volume 16, P. 4289 - 4319
Published: June 1, 2021
Abstract:
Recent
developments
in
three-dimensional
(3D)
printing
technology
offer
immense
potential
fabricating
scaffolds
and
implants
for
various
biomedical
applications,
especially
bone
repair
regeneration.
As
the
availability
of
autologous
sources
commercial
products
is
limited
surgical
methods
do
not
help
complete
regeneration,
it
necessary
to
develop
alternative
approaches
repairing
large
segmental
defects.
The
3D
can
effectively
integrate
different
types
living
cells
within
a
construct
made
up
conventional
micro-
or
nanoscale
biomaterials
create
an
artificial
graft
capable
regenerating
damaged
tissues.
This
article
reviews
applications
tissue
engineering
highlights
numerous
nanomaterials
that
have
been
used
production
3D-printed
scaffolds.
A
comprehensive
overview
such
as
stereolithography
(SLA),
selective
laser
sintering
(SLS),
fused
deposition
modeling
(FDM),
ink-jet
printing,
their
technical
clinical
regeneration
has
provided.
review
expected
be
useful
readers
gain
insight
into
state-of-the-art
substitutes
translational
perspectives.
Keywords:
bone,
engineering,
biomaterials,
Polymers,
Journal Year:
2021,
Volume and Issue:
13(5), P. 753 - 753
Published: Feb. 28, 2021
The
use
of
additive
manufacturing
(AM)
has
moved
well
beyond
prototyping
and
been
established
as
a
highly
versatile
method
with
demonstrated
potential
to
completely
transform
traditional
in
the
future.
In
this
paper,
comprehensive
review
critical
analyses
recent
advances
achievements
field
different
AM
processes
for
polymers,
their
composites
nanocomposites,
elastomers
multi
materials,
shape
memory
polymers
thermo-responsive
materials
are
presented.
Moreover,
applications
fields
such
bio-medical,
electronics,
textiles,
aerospace
industries
also
discussed.
We
conclude
article
an
account
further
research
needs
future
perspectives
process
polymeric
materials.
Bioactive Materials,
Journal Year:
2018,
Volume and Issue:
4, P. 22 - 36
Published: Nov. 26, 2018
The
application
of
various
materials
in
biomedical
procedures
has
recently
experienced
rapid
growth.
One
area
that
is
currently
receiving
significant
attention
from
the
scientific
community
treatment
a
number
different
types
bone-related
diseases
and
disorders
by
using
biodegradable
polymer-ceramic
composites.
Biomaterials,
most
common
used
to
repair
or
replace
damaged
parts
human
body,
can
be
categorized
into
three
major
groups:
metals,
ceramics,
polymers.
Composites
manufactured
combining
two
more
achieve
enhanced
biocompatibility
biomechanical
properties
for
specific
applications.
Biomaterials
must
display
suitable
their
applications,
about
strength,
durability,
biological
influence.
Metals
alloys
such
as
titanium,
stainless
steel,
cobalt-based
have
been
widely
investigated
implant-device
applications
because
excellent
mechanical
properties.
However,
these
may
also
manifest
issues
toxicity,
poor
tissue
adhesion
stress
shielding
effect
due
high
elastic
modulus.
To
mitigate
issues,
hydroxyapatite
(HA)
coatings
on
metals
chemical
composition
similar
bone
teeth.
Recently,
wide
range
synthetic
polymers
poly
(l-lactic
acid)
(l-lactide-co-glycolide)
studied
owing
promising
biodegradability.
This
article
gives
an
overview
composites
with
particular
emphasis
calcium
phosphate
group
potential
engineering.
It
hoped
PLLA/HA
PCL/HA
will
provide
advantages
eliminating
consequent
need
revision
surgery.
Pharmaceutics,
Journal Year:
2019,
Volume and Issue:
11(4), P. 165 - 165
Published: April 4, 2019
Lignin
(LIG)
is
a
natural
biopolymer
with
well-known
antioxidant
capabilities.
Accordingly,
in
the
present
work,
method
to
combine
LIG
poly(lactic
acid)
(PLA)
for
fused
filament
fabrication
applications
(FFF)
proposed.
For
this
purpose,
PLA
pellets
were
successfully
coated
powder
and
biocompatible
oil
(castor
oil).
The
resulting
placed
into
an
extruder
at
200
°C.
filaments
contained
loadings
ranging
from
0%
3%
(w/w).
obtained
used
FFF
applications.
content
affected
mechanical
surface
properties
of
overall
material.
inclusion
yielded
materials
lower
resistance
fracture
higher
wettabilities.
Moreover,
3D
printed
showed
By
using
2,2-diphenyl-1-picrylhydrazyl
(DPPH)
method,
capable
reducing
concentration
compound
up
ca.
80%
5
h.
This
radical
scavenging
activity
could
be
potentially
beneficial
healthcare
applications,
especially
wound
care.
PLA/LIG
design
meshes
different
designs
dressing
purposes.
A
healing
model
compound,
curcumin
(CUR),
was
applied
mesh
its
diffusion
studied.
It
observed
that
dimensions
permeation
rate
CUR.
modified
according
patient's
needs.
Journal of Manufacturing and Materials Processing,
Journal Year:
2021,
Volume and Issue:
5(3), P. 69 - 69
Published: June 29, 2021
Fused
filament
fabrication
(FFF)
is
one
of
the
most
popular
additive
manufacturing
(AM)
processes
that
utilize
thermoplastic
polymers
to
produce
three-dimensional
(3D)
geometry
products.
The
FFF
materials
have
a
significant
role
in
determining
properties
final
part
produced,
such
as
mechanical
properties,
thermal
conductivity,
and
electrical
conductivity.
This
article
intensively
reviews
state-of-the-art
for
filaments.
To
date,
there
are
many
different
types
been
developed.
range
from
pure
thermoplastics
composites,
bioplastics,
composites
bioplastics.
Different
reinforcements
particles,
fibers,
nanoparticles
incorporated
into
composite
filaments
improve
build
properties.
performance,
limitations,
opportunities
specific
type
will
be
discussed.
Additionally,
challenges
requirements
production
evaluated.
In
addition,
provide
concise
review
fundamental
knowledge
about
filament,
this
also
highlight
potential
research
directions
stimulate
future
development.
Finally,
importance
scopes
using
bioplastics
their
developing
eco-friendly
introduced.
Advanced Science,
Journal Year:
2022,
Volume and Issue:
9(12)
Published: Feb. 18, 2022
The
treatment
of
peripheral
nerve
defects
has
always
been
one
the
most
challenging
clinical
practices
in
neurosurgery.
Currently,
autograft
is
preferred
modality
for
defects,
while
therapy
constantly
plagued
by
limited
donor,
loss
donor
function,
formation
neuroma,
distortion
or
dislocation,
and
diameter
mismatch.
To
address
these
issues,
emerged
guide
conduits
(NGCs)
are
expected
to
offer
effective
platforms
repair
especially
those
with
large
complex
topological
structures.
Up
now,
numerous
technologies
developed
preparing
diverse
NGCs,
such
as
solvent
casting,
gas
foaming,
phase
separation,
freeze-drying,
melt
molding,
electrospinning,
three-dimensional
(3D)
printing.
3D
printing
shows
great
potential
advantages
because
it
can
quickly
accurately
manufacture
required
NGCs
from
various
natural
synthetic
materials.
This
review
introduces
application
personalized
printed
precision
predicts
their
future
directions.
Materials Science and Engineering C,
Journal Year:
2021,
Volume and Issue:
127, P. 112216 - 112216
Published: May 29, 2021
Additive
manufacturing
(AM)
is
recently
imposing
as
a
fast,
reliable,
and
highly
flexible
solution
to
process
various
materials,
that
range
from
metals
polymers,
achieve
broad
variety
of
customized
end-goods
without
involving
the
injection
molding
process.
The
employment
biomaterials
utmost
relevance
environmental
footprint
and,
consequently,
significantly
decreased.
can
provide,
in
particular,
an
all-in-one
platform
fabricate
complex-shaped
biobased
items
such
bone
implants
or
biomedical
devices,
would
be,
otherwise,
extremely
troublesome
costly
achieve.
Polyhydroxyalkanoates
(PHAs)
emerging
class
biodegradable
polymeric
materials
achievable
by
fermentation
bacteria.
There
are
some
promising
scientific
technical
reports
on
several
commodities
PHAs
additive
manufacturing.
However,
many
challenges
must
still
be
faced
order
expand
further
use
PHAs.
In
this
framework,
present
work
reviews
classifies
relevant
papers
focused
design
development
for
different
3D
printing
techniques
overviews
most
recent
applications
approach.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(2), P. 464 - 464
Published: Feb. 21, 2022
Skin
tissue
engineering
and
regeneration
aim
at
repairing
defective
skin
injuries
progress
in
wound
healing.
Until
now,
even
though
several
developments
are
made
this
field,
it
is
still
challenging
to
face
the
complexity
of
with
current
methods
fabrication.
In
review,
short,
state-of-the-art
on
using
3D
bioprinting
as
a
new
tool
described.
The
summary
bioink
formulations,
parameters,
properties
discussed.
Finally,
representative
number
examples
advances
field
together
limitations
future
needs
provided.
