Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 24
Published: Jan. 1, 2024
Language: Английский
ACS Omega, Journal Year: 2023, Volume and Issue: 8(16), P. 14290 - 14320
Published: April 10, 2023
Cancer is ranked as the second leading cause of death globally. Traditional cancer therapies including chemotherapy are flawed, with off-target and on-target toxicities on normal cells, requiring newer strategies to improve cell selective targeting. The application nanomaterial has been extensively studied explored chemical biology tools in theranostics. It shows greater applications toward stability, biocompatibility, increased permeability, resulting precise targeting, mitigating shortcomings traditional therapies. nanoplatform offers an exciting opportunity gain targeting multifunctionality. advent nanotechnology, particular development smart nanomaterials, transformed diagnosis treatment. large surface area nanoparticles enough encapsulate many molecules ability functionalize various biosubstrates such DNA, RNA, aptamers, antibodies, which helps theranostic action. Comparatively, biologically derived nanomaterials perceive advantages over produced by conventional methods terms economy, ease production, reduced toxicity. present review summarizes techniques theranostics emphasizes (such organic (NPs), inorganic NPs, carbon-based NPs). We also critically discussed challenges impeding their translation treatment diagnostic applications. This concludes that use could significantly will facilitate new dimensions for tumor detection therapy.
Language: Английский
Citations
163
Biosensors, Journal Year: 2023, Volume and Issue: 13(1), P. 80 - 80
Published: Jan. 3, 2023
Breast cancer (BC) is the most common in women, which also second public worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond breast. In recent years, various biosensor strategies have been studied, including optical, electrical, electrochemical, mechanical biosensors. particular, high sensitivity short detection time of electrochemical biosensors make them suitable for recognition biomarkers. Moreover, increased by incorporating nanomaterials. this respect, outstanding electrical performances graphene led to an increasingly intense study graphene-based materials Hence, present review examines latest advances biosensing. For each biosensor, limit (LOD), linear range (LR), diagnosis technique are analyzed. This followed a discussion prospects current challenges, along with potential enhancing performance
Language: Английский
Citations
51
Cancer Cell International, Journal Year: 2024, Volume and Issue: 24(1)
Published: March 16, 2024
Abstract Conventional cancer treatments can cause serious side effects because they are not specific to cells and damage healthy cells. Aptamers often single-stranded oligonucleotides arranged in a unique architecture, allowing them bind specifically target sites. This feature makes an ideal choice for targeted therapeutics. They typically produced through the systematic evolution of ligands by exponential enrichment (SELEX) undergo extensive pharmacological revision modify their affinity, specificity, therapeutic half-life. act as drugs themselves, directly inhibiting tumor Alternatively, be used drug delivery systems transport cells, minimizing toxicity In this review, we will discuss latest most advanced approaches using aptamers treatment, particularly therapy overcoming resistance conventional therapies.
Language: Английский
Citations
34
Progress in Materials Science, Journal Year: 2023, Volume and Issue: 136, P. 101110 - 101110
Published: March 7, 2023
Language: Английский
Citations
35
Chinese Chemical Letters, Journal Year: 2023, Volume and Issue: 35(2), P. 108528 - 108528
Published: April 30, 2023
Language: Английский
Citations
23
International Immunopharmacology, Journal Year: 2025, Volume and Issue: 148, P. 114121 - 114121
Published: Jan. 31, 2025
Language: Английский
Citations
1
Chinese Chemical Letters, Journal Year: 2022, Volume and Issue: 33(9), P. 4208 - 4212
Published: Feb. 3, 2022
Language: Английский
Citations
31
Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14
Published: March 10, 2023
Immunotherapy is a type of treatment that uses our own immune system to fight cancer. Studies have shown traditional Chinese medicine (TCM) has antitumor activity and can enhance host immunity. This article briefly describes the immunomodulatory escape mechanisms in tumors, as well highlights summarizes activities some representative active ingredients TCM. Finally, this puts forward opinions on future research clinical application TCM, aiming promote applications TCM tumor immunotherapy provide new ideas for using
Language: Английский
Citations
18
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 262, P. 130032 - 130032
Published: Feb. 9, 2024
Language: Английский
Citations
7
Polymers, Journal Year: 2024, Volume and Issue: 16(5), P. 584 - 584
Published: Feb. 21, 2024
It has been shown that there exist conditions under which thermosensitive copolymers of N-vinylpyrrolidone with methyl acrylate form hydrophobic–hydrophilic associations, are unstable dynamic meshes, the bonds in continuously broken and created again, nature formation such meshes depends significantly on proportion hydrophobic component copolymer. is interaction above polyacrylic acid results not only classical interpolymer complexes, but also hydrophilic associates, represent networks existing a mode. In molecules serve as kind cross-agent connecting polyacid molecules. There acquire complex structure, since between macromolecular tangles both same different types take part their formation. transition from complexes to associates can occur, among other things, due changes acidity or concentration low-molecular salt solution.
Language: Английский
Citations
7