Reactive and Functional Polymers, Journal Year: 2023, Volume and Issue: 192, P. 105729 - 105729
Published: Sept. 20, 2023
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(36), P. 46988 - 47002
Published: Aug. 27, 2024
Early cancer detection is crucial for effective treatment, but current methods have limitations. Novel biomaterials, such as hydrogels, offer promising alternatives developing biosensors detection. Hydrogels are three-dimensional and cross-linked networks of hydrophilic polymers that properties similar to biological tissues. They can be combined with various achieve high sensitivity, specificity, stability. This review summarizes the recent advances in hydrogel-based detection, their synthesis, applications, challenges. It also discusses implications future directions this emerging field.
Language: Английский
Citations
15
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134015 - 134015
Published: July 20, 2024
Language: Английский
Citations
7
Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 149, P. 104546 - 104546
Published: May 17, 2024
Language: Английский
Citations
6
Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 401, P. 124629 - 124629
Published: March 31, 2024
Language: Английский
Citations
4
Sensing and Bio-Sensing Research, Journal Year: 2025, Volume and Issue: unknown, P. 100783 - 100783
Published: April 1, 2025
Language: Английский
Citations
0
Critical Reviews in Food Science and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20
Published: April 6, 2025
DNAzyme-based biosensors have emerged as a promising tool for ensuring food safety due to their high sensitivity, specificity, and potential rapid, cost-effective detection of hazardous substances. These leverage DNAzymes-catalytically active DNA molecules-to detect range contaminants, including metal ions, fungal toxins, pesticides, pathogens. While show significant advantages over conventional techniques, challenges such nuclease degradation, interference from complex sample matrices, the costs associated with DNAzyme synthesis still hinder widespread application. Recent advancements in stability DNAzymes, immobilization strategies, integration nanomaterials are progressively addressing these limitations, enhancing performance reliability sensors. This review highlights structural catalytic characteristics assesses current applications safety, discusses innovative strategies overcome existing challenges. The continuous evolution biosensors, particularly design device integration, holds great promise future role routine, reliable analysis.
Language: Английский
Citations
0
Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 10, 2025
Abstract DNA hydrogels have emerged as promising materials in tissue engineering due to their biocompatibility, programmability, and responsiveness stimuli. Synthesized through physical chemical crosslinking, these can be categorized into functionalized types, such those based on aptamers, stimuli‐responsive types that react pH, temperature, light. This review highlights applications engineering, including drug delivery, cell culture, biosensing, gene editing. encapsulate therapeutic agents, support growth, respond dynamically environmental changes, making them ideal for engineering. A comprehensive bibliometric analysis is included, identifying key research trends emerging areas of interest hydrogel design, synthesis, biomedical applications. The provides a deeper understanding the field's development future directions. Challenges mechanical strength, stability, biosafety persist, but integration AI design shows promise advancing functionality clinical
Language: Английский
Citations
0
ACS Applied Engineering Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 23, 2025
Language: Английский
Citations
0
TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117907 - 117907
Published: Aug. 13, 2024
Language: Английский
Citations
3
Biosensors, Journal Year: 2023, Volume and Issue: 13(7), P. 755 - 755
Published: July 23, 2023
DNA hydrogels have gained significant attention in recent years as one of the most promising functional polymer materials. To broaden their applications, it is critical to develop efficient methods for preparation bulk-scale with adjustable mechanical properties. Herein, we introduce a straightforward and molecular design approach producing physically pure hydrogel controlling its properties by adjusting degree hydrogen bonding ultralong single-stranded (ssDNA) precursors, which were generated using dual rolling circle amplification (RCA)-based strategy. The effect on performance was thoroughly investigated analyzing process, morphology, rheology, microstructure, entrapment efficiency Au nanoparticles (AuNPs)-BSA. Our results demonstrate that can be formed at 25 °C simple vortex mixing less than 10 s. experimental also indicate higher precursor resulted stronger internal interaction forces, more complex network hydrogel, denser improved properties, enhanced efficiency. This study intuitively demonstrates hydrogels. method presented this are great significance improving synthesis economy hydrogels, enhancing overall quality expanding application field
Language: Английский
Citations
6