A polarization independent highly sensitive metasurface-based biosensor for lab-on-chip applications

Measurement, Journal Year: 2024, Volume and Issue: 231, P. 114652 - 114652

Published: April 6, 2024

Language: Английский

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Recent advancements of smartphone-based sensing technology for diagnosis, food safety analysis, and environmental monitoring

Talanta, Journal Year: 2024, Volume and Issue: 275, P. 126080 - 126080

Published: April 10, 2024

Language: Английский

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Design and Analysis of a Plasmonic Metasurface-Based Graphene Sensor for Highly Sensitive and Label-Free Detection of COVID-19 Biomarkers

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: July 27, 2024

Language: Английский

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Design and Analysis of a Graphene/Gold Nanostructure Metasurface Surface Plasmon Resonance Sensor for Biomedical Applications

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 8, 2024

Language: Английский

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Emerging Multifunctional Carbon‐Nanomaterial‐Based Biosensors for Cancer Diagnosis

Small Science, Journal Year: 2024, Volume and Issue: 4(3)

Published: Jan. 22, 2024

Despite significant advancements in medical technology, cancer remains the world's second‐leading cause of death, largely attributed to late‐stage diagnoses. While traditional detection methodologies offer foundational insights, they often lack specificity, affordability, and sensitivity for early‐stage identification. In this context, development biosensors offers a distinct possibility precise rapid identification biomarkers. Carbon nanomaterials, including graphene, carbon nitride, quantum dots, other carbon‐based nanostructures, are highly promising detection. Their simplicity, high sensitivity, cost‐effectiveness contribute their potential field. This review aims elucidate emerging carbon‐nanomaterial‐based early diagnosis. The relevance various biosensor mechanisms performance physicochemical properties nanomaterials is discussed depth, focusing on demonstrating broad creating biosensors. Diverse techniques, such as electrochemical, fluorescence, surface plasmon resonance, electrochemiluminescence, quartz crystal microbalance, emphasized At last, summary existing challenges future outlook field elaborated.

Language: Английский

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A Novel CRISPR/Cas12a-Mediated Ratiometric Dual-Signal Electrochemical Biosensor for Ultrasensitive and Reliable Detection of Circulating Tumor Deoxyribonucleic Acid

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(18), P. 6930 - 6939

Published: April 23, 2024

Circulating tumor DNA (ctDNA) holds great promise as a noninvasive biomarker for cancer diagnosis, treatment, and prognosis. However, the accurate specific quantification of low-abundance ctDNA in serum remains significant challenge. This study introduced, first time, novel exponential amplification reaction (EXPAR)-assisted CRISPR/Cas12a-mediated ratiometric dual-signal electrochemical biosensor ultrasensitive reliable detection ctDNA. To implement strategy, signal unit (ssDNA-MB@Fc/UiO-66-NH

Language: Английский

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Machine Learning Optimized Optical Surface Plasmon Resonance Biosensor Using Locally Weighted Linear Regression for Rapid and Accurate Detection of Tuberculosis Biomarkers

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 8, 2025

Language: Английский

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SPR Biosensor Based on Bilayer MoS2 for SARS-CoV-2 Sensing

Biosensors, Journal Year: 2025, Volume and Issue: 15(1), P. 21 - 21

Published: Jan. 4, 2025

The COVID-19 pandemic has highlighted the urgent need for rapid, sensitive, and reliable diagnostic tools detecting SARS-CoV-2. In this study, we developed optimized a surface plasmon resonance (SPR) biosensor incorporating advanced materials to enhance its sensitivity specificity. Key parameters, including thickness of silver layer, silicon nitride dielectric molybdenum disulfide (MoS2) layers, ssDNA recognition were systematically achieve best balance between sensitivity, resolution, attenuation. configuration, consisting 45 nm 13 2 MoS2 5 demonstrated superior performance SARS-CoV-2 in PBS solution. exhibited high at low viral concentrations, achieving 375.01°/RIU, detection accuracy 0.002, quality factor 38.34 1.0 mM concentration. Performance metrics validated sensor’s capability detection, particularly early-stage diagnostics where timely intervention is critical. Moreover, biosensor’s linear response refractive index changes confirmed potential quantitative concentration analysis. This study underlines significance integrating materials, such as nitride, SPR performance. findings establish proposed robust precise tool with applications clinical epidemiological monitoring.

Language: Английский

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Optimizing drug discovery: Surface plasmon resonance techniques and their multifaceted applications

Chemical Physics Impact, Journal Year: 2023, Volume and Issue: 8, P. 100414 - 100414

Published: Dec. 5, 2023

In recent years, researchers have made significant contributions to the field of Surface Plasmon Resonance sensors and their potential applications. SPR features include real-time monitoring biomolecular interactions, label-free detection, high sensitivity, ability analyze multiple samples at same time. These characteristics make biosensors a valuable tool in pharmaceutical industry for ensuring drug efficacy safety. Furthermore, reputation providing quantitative qualitative superior performance applications such as development, environmental monitoring, food safety, medical diagnostics, clinical diagnosis, biological investigations, biomolecule interactions. This review will go over advances how they can be used discovery development. We also look challenges opportunities using industry.

Language: Английский

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Detection of Proteins in a Surface Plasmon Resonance Biosensor Based on Hybrid Metasurface Architecture and Behaviour Prediction Using Random Forest Regression

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Language: Английский

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