A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(1), P. 124 - 124
Published: Jan. 18, 2024
The
extraction
of
bioactive
compounds
pharmaceutical
interest
from
natural
sources
has
been
significantly
explored
in
recent
decades.
However,
the
techniques
used
were
not
very
efficient
terms
time
and
energy
consumption;
additionally,
solvents
for
harmful
environment.
To
improve
environmental
impact
extractions
at
same
increase
yields,
several
new
developed.
Among
most
ones
are
ultrasound-assisted
microwave-assisted
extraction.
These
increased
yield
selectivity
a
smaller
amount
with
decrease
consumption.
Nevertheless,
high
volume
organic
was
still
extraction,
causing
subsequent
problem.
Neoteric
appeared
as
green
alternatives
to
solvents.
neoteric
solvents,
deep
eutectic
evidenced
be
one
best
due
their
intrinsic
characteristics.
considered
because
they
made
up
such
sugars,
amino
acids,
carboxylic
acids
having
low
toxicity
degradability.
In
addition,
simple
prepare,
an
atomic
economy
100%,
attractive
physicochemical
properties.
Furthermore,
huge
number
that
can
synthesize
these
make
them
useful
since
tailored
selective
towards
specific
component
or
class
components.
main
aim
this
paper
is
give
comprehensive
review
which
describes
properties,
characteristics,
production
methods
well
its
application
extract
interest.
Additionally,
overview
more
sustainable
also
given.
Language: Английский
Green Extraction of Polyphenols via Deep Eutectic Solvents and Assisted Technologies from Agri-Food By-Products
Molecules,
Journal Year:
2023,
Volume and Issue:
28(19), P. 6852 - 6852
Published: Sept. 28, 2023
Polyphenols
are
the
largest
group
of
phytochemicals
with
important
biological
properties.
Their
presence
in
conveniently
available
low-cost
sources,
such
as
agri-food
by-products,
has
gained
considerable
attention
their
recovery
and
further
exploitation.
Retrieving
polyphenols
a
green
sustainable
way
is
crucial.
Recently,
deep
eutectic
solvents
(DESs)
have
been
identified
safe
environmentally
benign
medium
capable
extracting
efficiently.
This
review
encompasses
current
knowledge
applications
DESs
assisted
technologies
to
extract
from
by-products.
Particular
paid
fundamental
mechanisms
potential
food,
cosmetic,
pharmaceutical
industries.
In
this
way,
DESs-assisted
advanced
techniques
offer
promising
opportunities
recover
by-products
efficiently,
contributing
circular
economy.
Language: Английский
Upgrading hazelnut skins: Green extraction of polyphenols from lab to semi-industrial scale
Food Chemistry,
Journal Year:
2024,
Volume and Issue:
463, P. 140999 - 140999
Published: Aug. 26, 2024
Hazelnut
skins
(HS)
are
usually
managed
as
waste;
however,
this
by-product
is
a
source
of
bioactive
compounds,
with
potential
applications
in
feed
and
food
sectors.
Phenolic
compounds
can
be
extracted
using
green
protocols
combining
enabling
technologies
solvents.
This
work
investigates
subcritical
water
extraction
(SWE)
from
HS.
A
laboratory-scale
study
was
performed
on
four
different
batches,
significant
batch-to-batch
heterogeneity.
The
evaluation
polyphenolic
profiles
antioxidant
activities
afforded
promising
results
compared
to
the
benchmark
reflux
maceration.
To
evaluate
process
effectiveness,
protocol
replicated
semi-industrial
plant
that
processed
8
kg
matrix.
Downstream
processes
have
been
optimized
for
scale-up,
demonstrating
effectiveness
SWE
retaining
product
concentration
bioactivity
avoiding
excipients
spray-drying
phase.
extracts
exhibited
antibacterial
properties
against
animal-
food-borne
pathogens,
supporting
their
use
sustainable
ingredients
improved
hazelnut
production
animal
farming
practices.
Language: Английский
From waste to therapeutics: extraction methodologies and biological properties of bioactive compounds from fruit and vegetable waste
Food Bioscience,
Journal Year:
2024,
Volume and Issue:
62, P. 105389 - 105389
Published: Nov. 1, 2024
Language: Английский
Usos de los subproductos de la papa en la industria alimentaria: RSL
TAYACAJA,
Journal Year:
2024,
Volume and Issue:
7(1), P. 02 - 19
Published: March 19, 2024
Este
artículo
de
revisión
sistemática
analiza
los
usos
subproductos
la
papa
en
industria
alimentaria,
resaltando
que
muchos
estos
son
desechados
al
medio
ambiente
sin
tratamiento
debido
a
su
bajo
valor
comercial,
lo
representa
un
riesgo
ambiental.
El
objetivo
del
estudio
es
realizar
una
literatura
acerca
se
realizan
identificando
32
artículos
relevantes
entre
3547
encontrados
base
datos
Scopus.
Los
resultados
muestran
pueden
ser
utilizados
como
ingrediente
formulaciones
alimentos,
extracción
compuestos
bioactivos
y
para
conservar
alimentos.
Según
el
análisis
manuscritos,
tienen
efecto
positivo
las
diversas
aplicaciones
mencionadas
por
sus
bioactivos,
donde
destacan
polifenoles
ácido
clorogénico,
cafeico
ferúlico
propiedades
antioxidantes
incorporadas
nuevas
alimentos
ofrecen
antimicrobianas,
antiinflamatorias
anticancerígenas.
Aunque
bibliografía
extensa,
aún
hay
áreas
requieren
más
investigación
aprovechar
manera
sostenible
siguiendo
economía
circular.
The Green Extraction of Blueberry By-Products: An Evaluation of the Bioactive Potential of the Anthocyanin/Polyphenol Fraction
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(20), P. 11032 - 11032
Published: Oct. 14, 2024
In
the
context
of
a
circular
economy,
this
study
explores
valorization
blueberry
pomace
(BP)
as
source
bioactive
compounds
using
sustainable
extraction
methods.
Microwave-assisted
(MAE)
and
microwave-assisted
subcritical
water
(MASWE)
were
employed
to
obtain
two
distinct
fractions:
MAE
1°
MASWE
2°.
The
first
extract,
1°,
obtained
at
80
°C,
had
high
total
anthocyanin
content
(21.96
mgCya-3-glu/gextract),
making
it
suitable
natural
pigment.
Additionally,
exhibited
significant
enzyme
inhibition,
particularly
against
α-amylase
β-glucosidase,
suggesting
potential
anti-diabetic
anti-viral
applications.
second
2°,
150
contained
higher
phenolic
(211.73
mgGAE/gextract)
demonstrated
stronger
antioxidant
activity.
2°
showed
greater
inhibition
acetylcholinesterase
tyrosinase,
indicating
its
for
use
in
Alzheimer’s
treatment,
skincare,
or
food
preservative.
cytotoxicity
HeLa
cells
effectively
mitigated
H2O2-induced
oxidative
stress
HaCat
cells,
with
showing
similar
but
less
pronounced
effects.
A
tested
formulation
combining
extracts
3:2
ratio
enhanced
stability,
demonstrating
heat-stable
extract
characteristics
compared
conventional
method
(MeOH-HCl
reflux
condition),
protocol’s
sustainability
was
assessed
several
green
metric
tools,
which
provided
insights
into
environmental
impact
efficiency.
Language: Английский
Potato waste and sweet potato waste utilization – some research trends
E3S Web of Conferences,
Journal Year:
2024,
Volume and Issue:
563, P. 03080 - 03080
Published: Jan. 1, 2024
The
aim
of
the
present
paper
was
to
show
in
a
summarized
and
systematized
form,
with
help
search
relevant
keywords
scientific
databases
applying
descriptive
approach,
some
current
research
trends
concerning
possibilities
for
potato
waste
sweet
utilization.
areas
which
intense
work
is
being
done
field
valorization
are
heterogeneous
diverse,
such
as
bioethanol
production,
anaerobic
digestion,
adsorption
dyes
heavy
metals,
recovery
bioactive
compounds,
production
composite
films,
synthesis
nanoparticles,
application
components
animal
nutrition,
attempts
include
them
ingredients
food
production.
goal
proper
treatment
sustainable
handling
these
materials
give
additional
value
utility,
derive
greatest
possible
benefit
from
them,
minimize
risks
negative
consequences
environment,
protect
wellbeing
society
whole.
Language: Английский
Natural deep eutectic solvents for efficient recovery of bioactive compounds from by-product of industrial hemp processing: Pretreatment, modeling and optimization
Industrial Crops and Products,
Journal Year:
2024,
Volume and Issue:
222, P. 119617 - 119617
Published: Sept. 12, 2024
Language: Английский
Research on the impact of domestic agricultural R&D on high-quality agricultural development in China
Frontiers in Sustainable Food Systems,
Journal Year:
2023,
Volume and Issue:
7
Published: Dec. 11, 2023
A
fresh
wave
of
technical
change
is
seen
as
one
the
most
effective
ways
to
achieve
sustainable
agricultural
development
due
declining
carrying
capacity
resources
and
environment.
China,
a
nation
with
sizable
population,
has
drawn
immense
research
attention
over
following
question:
How
can
China
promote
transformation
high-quality
through
technological
innovation?
Based
on
panel
data
that
considers
28
provincial-level
administrative
regions
in
mainland
from
2010
2018,
study
utilizes
two-way
fixed
models;
thus,
it
tests
impact
domestic
development.
Furthermore,
moderating
effect
verify
relationship
between
two
aforementioned
factors
under
influence
foreign
technology
introduction,
human
capital,
financial
support.
We
observed
following:
First,
characterized
all
Chinese
exhibited
steady
upward
trend.
The
industrial
system,
ecological
management
system
considerable
development,
whereas
production
was
lagging.
Second,
promoted
Third,
support,
promotion
gradually
weakened.
This
presents
various
proposals;
strengthens
role
promoting
Language: Английский