Placental histopathology after SARS-CoV-2 infection in pregnancy: a systematic review and meta-analysis

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2021, Volume and Issue: 3(6), P. 100468 - 100468

Published: Aug. 21, 2021

Language: Английский

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The role of pharmacological interventions in managing urological complications during pregnancy and childbirth: A review

Medicine, Journal Year: 2025, Volume and Issue: 104(7), P. e41381 - e41381

Published: Feb. 14, 2025

Pregnancy leads to a number of structural and functional changes in the urinary system, which makes females susceptible urological complications. This review aims discuss epidemiology, complications prevention management tract infections (UTIs), kidney stones bladder dysfunction pregnancy. UTIs are most common problem presenting 10% pregnant women; Escherichia coli is causative organism. If left untreated, lead acute pyelonephritis occurs about 2% women has serious consequences for both mother baby. Kidney stones, although rare, hazardous, occurring 1 200 1500 pregnancies, may cause obstructive uropathy, aggravation “labor-like” pain. Urological frequent pregnancy; alone been documented affect 50% women. can have severe when not properly managed including preterm labor renal dysfunction. In order best pharmacological care, safe use antibiotics needed along with other measures stones. highlights importance team approach patient optimize outcome touches briefly on some ethical dilemmas that be encountered drug therapy pregnancy being considered. Therefore, it feasible enhance health fetus during this period through focused care innovative interventions.

Language: Английский

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SARS-CoV-2 infection during pregnancy and pregnancy-related conditions: Concerns, challenges, management and mitigation strategies–a narrative review

Journal of Infection and Public Health, Journal Year: 2021, Volume and Issue: 14(7), P. 863 - 875

Published: April 23, 2021

The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), is a global public health problem. SARS-CoV-2 triggers hyper-activation of inflammatory and immune responses resulting in cytokine storm increased on several organs like lungs, kidneys, intestine, placenta. Although affects individuals all age groups physiological statuses, immune-compromised such as pregnant women are considered highly vulnerable group. This review aims to raise the concerns high risk infection, morbidity mortality COVID-19 provides critical reviews pathophysiology pathobiology how infection potentially increases severity fatality during pregnancy. article also discussion current evidence vertical transmission pregnancy breastfeeding. Lastly, guidelines management, treatment, preventive, mitigation strategies pregnancy-related conditions delivery breastfeeding discussed.

Language: Английский

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Counseling in maternal–fetal medicine: SARS‐CoV‐2 infection in pregnancy

Ultrasound in Obstetrics and Gynecology, Journal Year: 2021, Volume and Issue: 57(5), P. 687 - 697

Published: March 16, 2021

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a zoonotic that crossed species to infect humans, causing disease 2019 (COVID‐19). Despite potentially higher risk of pregnant women acquiring SARS‐CoV‐2 infection compared with the non‐pregnant population (particularly in some ethnic minorities), no additional specific recommendations avoid exposure are needed pregnancy. The most common clinical symptoms and laboratory signs pregnancy fever, cough, lymphopenia elevated C‐reactive protein levels. Pregnancy associated severe population, including pneumonia, admission intensive care unit death, even after adjusting for potential factors outcomes. miscarriage does not appear be increased infection. Evidence regards preterm birth perinatal mortality conflicting, but these risks generally only symptomatic, hospitalized women. vertical transmission, defined as transmission from mother fetus or newborn, low. Fetal invasive procedures considered safe infection, although evidence still limited. In COVID‐19, use steroids should avoided if clinically indicated; preferred regimen 2‐day course dexamethasone followed by an 8‐day methylprednisolone. Non‐steroidal anti‐inflammatory drugs may used there contraindications. Hospitalized COVID‐19 undergo thromboprophylaxis throughout duration hospitalization at least until discharge, preferably low molecular weight heparin. who have recovered period serious critical illness offered fetal growth scan about 14 days recovery their illness. asymptomatic mildly symptomatic tested positive full term (i.e. ≥ 39 weeks gestation), induction labor might reasonable. To date, clear consensus on optimal timing delivery critically ill few symptoms, management follow routine evidence‐based guidelines. Regardless status, mothers infants remain together breastfeeding, skin‐to‐skin contact, kangaroo rooming‐in day night practiced, while applying necessary prevention control measures. Many already undergone vaccination, mostly USA where first reports show significant difference outcomes receiving vaccination during background risk. Vaccine‐generated antibodies were present umbilical cord blood breast milk samples lactating received mRNA vaccine. Based available limited data safety vaccine pregnancy, it seems reasonable offer option accurate counseling unknown © 2021 International Society Ultrasound Obstetrics Gynecology.

Language: Английский

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Effects of the Covid-19 pandemic on maternity staff in 2020 – a scoping review

BMC Health Services Research, Journal Year: 2021, Volume and Issue: 21(1)

Published: Dec. 1, 2021

Abstract In the spring of 2020, SARS-CoV-2 virus caused Covid-19 pandemic, bringing with it drastic changes and challenges for health systems medical staff. Among affected were obstetricians midwives, whose close physical contact pregnant women, women who recently gave birth, their children was indispensable. obstetric setting, births cannot be postponed, maternity staff had to adapt assure safety while balancing evidence-based standards new posed by pandemic. This scoping review gives a comprehensive overview effecs pandemic on We followed approach described Arksey & O’Malley: we searched several databases English German articles published between January 2020 2021 that discussed or touched upon effects in OECD countries China. found structural crisis its subjective fell into two main topic areas. Structural (the first topic) divided five subtopics: shortages restructuring; personal protective equipment tests; switching virtual communication; handling positive infection; excluding accompanying persons. The also strongly staff’s mental second topic.) Attempting meet afraid contamination, suffering overwork exhaustion, struggling resolve ethical-moral dilemmas severe negative effects. Several studies indicated increased depression, anxiety, stress levels, risk post-traumatic symptoms, although generated strong occupational solidarity. Care pregnant, birthing, breast-feeding interrupted, even during requires social distancing. Maternity sometimes abandon normal care confronted enormous adjustments did not leave them unscathed: suffered considerably. Researchers should study experiences prepare recommendations will protect future epidemics.

Language: Английский

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Psychological and Biochemical Effects of an Online Pilates Intervention in Pregnant Women during COVID-19: A Randomized Pilot Study

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(17), P. 10931 - 10931

Published: Sept. 1, 2022

The purpose of this study was to analyze the effect real-time online Pilates exercise during COVID-19 on women’s body composition, blood lipids, and psychological health after childbirth. participants were 16 pregnant women (24–28 weeks pregnant) enrolled at C Women’s Culture Center in Seoul, South Korea, classified into groups non-exercise (PE, n = 8; CON, 8). program conducted for 8 weeks, twice a week, 50 min day using video chat app. Participants visited hospital composition tests. Questionnaires postpartum depression, sleep disorder, stress 6 12 We found significant difference between composition. weight, percentage fat, fat mass, BMI PE group decreased. Blood lipids showed differences TC, TG, LDL CRP, while insulin HDL no difference. All insulin, CRP reduced. There disorders, perceived indices performed post-test, serotonin concentration increased. Serotonin levels significantly correlated with rate. Pregnant effective reducing weight depression childbirth should be used promote mental COVID-19.

Language: Английский

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Pregnancy and Severe ARDS with COVID-19: Epidemiology, Diagnosis, Outcomes and Treatment

Seminars in Fetal and Neonatal Medicine, Journal Year: 2023, Volume and Issue: 28(1), P. 101426 - 101426

Published: Feb. 1, 2023

Pregnancy-related acute respiratory distress syndrome (ARDS) is fast becoming a growing and clinically relevant subgroup of ARDS amidst global outbreaks various viral pathogens that include H1N1-influenza, severe (SARS), middle east (MERS), the most recent COVID-19 pandemic. Pregnancy risk factor for viral-induced commonly associated with poor maternal fetal outcomes including growth-restriction, preterm birth, spontaneous abortion. Physiologic changes pregnancy further compounded by mechanical immunologic alterations are theorized to impact development from pneumonia. The sub-phenotype share overlapping molecular features pathogenicity respect immune-dysregulation endothelial/microvascular injury (i.e., preeclampsia) may in part explain trend toward seen infections. To date, current diagnostic criteria treatment management fail consider physiologic adaptations unique physiology consideration maternal-fetal interactions. Treatment focused on lung-protective ventilation strategies have been shown improve clinical adults but adverse interactions when applied pregnancy-related ARDS. No specific pharmacotherapy has identified Adjunctive therapies aimed at immune-modulation anti-viral infection during reported data regard its efficacy safety currently lacking.

Language: Английский

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“Never let a good crisis go to waste”: Positives from disrupted maternity care in Australia during COVID-19

Midwifery, Journal Year: 2022, Volume and Issue: 110, P. 103340 - 103340

Published: April 17, 2022

Due to the COVID-19 pandemic, a number of changes maternity care were rapidly introduced in all countries, including Australia, reduce risk infection for pregnant women and their providers. While many studies have reported on negative effects these changes, there is paucity evidence factors which providers perceived as positive useful future care.Data was analysed from Birth time (BITTOC 2020) study survey. Conventional content analysis descriptive statistics used analyse data examine aspects COVID-amended experienced positive. Data compared midwives.This project took place Australia 2020-2021.The survey distributed who gave birth midwives worked during pandemic (March 2020 onwards).Women variety positives COVID-19. These included both care-related well contextual factors. The most commonly mentioned postnatal care-related, namely fewer visitors hospital, having increased access telehealth services. also by midwives. Having midwifery continuity models, giving at home partner work highlighted positives.Despite effect COVID-19-related restrictions care, viewed midwives, with strong agreement between two groups.These findings provide support inclusion elements ensure that lessons learned are utilised improve going forward.

Language: Английский

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Home birth in Iran during the COVID-19 pandemic: a qualitative study

British Journal of Midwifery, Journal Year: 2025, Volume and Issue: 33(4), P. 200 - 207

Published: April 1, 2025

Background/Aims Various factors can influence a woman's decision on where to give birth, and the COVID-19 pandemic led reported increase in home births. This study aimed explore Iranian couples' experiences of birth at during pandemic. Methods qualitative gathered data from purposive sample six women four men via in-depth semi-structured interviews. Conventional content analysis was used. Results The main theme, ‘linking dread joy’, had two subthemes describing that influenced participants' experiences: subjective factors, such as faith, motivation curiosity, objective having an experienced midwife suitable equipment. Conclusions Home planning could be included safe guidelines for Iran. would need consider all aspects health (physical psychological) needs preferences with low-risk pregnancies. Implications practice It is recommended further efforts made examine status across

Language: Английский

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Postpartum Depressive Symptoms and Experiences During COVID-19

MCN The American Journal of Maternal/Child Nursing, Journal Year: 2021, Volume and Issue: 47(2), P. 77 - 84

Published: Nov. 30, 2021

Abstract Purpose: To identify postpartum depression risk and describe experiences of women in the first 6 weeks after giving birth during COVID-19 pandemic. Study Design Methods: Using a convergent mixed-methods approach, we recruited convenience sample living United States who gave March 1, 2020 or later from social media Web sites. Participants completed Postpartum Depression Screening Scale-Short Form provided written answers to open-ended questions regarding their at home with new infant. Results: Our 262 participants were on average 32.6 years age, majority White (82%), married partnered (91.9%), college educated (87.4%). Mean score was 17.7 ( SD = 5.9) 75% scoring ≥14, indicating significant depressive symptoms. Qualitative content analysis revealed five themes: Isolation seclusion continue ; Fear, anxiety, stress filled days Grieving loss normal: It's just so sad Complicated by depression: A dark time There is silver lining . Quantitative qualitative findings holistic view women's symptoms infants Clinical Implications: Although policies that reduce exposure infection for patients health care team must be implemented, adverse effects maternal–infant wellbeing within context increased isolation due pandemic need kept forefront. Nurses aware consequences sheltering place distancing outcomes, particularly likelihood breastfeeding.

Language: Английский

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