Ashwagandha (Withania somnifera) and Shunthi (Zingiber officinale) in mild and moderate COVID-19: An open-label randomized controlled exploratory trial

Complementary Therapies in Medicine, Journal Year: 2023, Volume and Issue: 76, P. 102966 - 102966

Published: July 22, 2023

Ayurveda interventions have been used for prophylaxis and care during the COVID-19 pandemic in India shown promising results promoting early clinical recovery from COVID-19.

Language: Английский

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Perceptions of medicinal herbal products during the COVID-19 pandemic period among Saudi patients: a cross-sectional study

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2023, Volume and Issue: 397(1), P. 497 - 506

Published: July 21, 2023

Language: Английский

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A Comprehensive Review on the Use of Herbal Dietary Supplements in the USA, Reasons for Their Use, and Review of Potential Hepatotoxicity

Livers, Journal Year: 2022, Volume and Issue: 2(3), P. 119 - 138

Published: Aug. 2, 2022

Herbal and dietary supplement (HDS) use has grown exponentially in the United States. Unfortunately, incidence of HDS-related liver injury proportionally increased. Despite potential for certain HDSs to cause clinically significant injury, they are not regulated by Food Drug Administration. Recent efforts have been made regulate but far removed from scrutiny prescription medications. Scant literature exists on their risks causing injury. In this comprehensive review, we examine trends HDS States pathophysiologic mechanisms drug-induced (DILI) HDSs. Finally, review usage rates; benefits, if any; purported pathophysiology DILI; propensity progression fulminant hepatic failure nine linked DILI.

Language: Английский

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Unlocking the therapeutic potential of edible mushrooms: Ganoderma and their secondary metabolites as novel antiviral agents for combating COVID-19

New Zealand Journal of Botany, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 59

Published: Aug. 8, 2024

The global COVID-19 pandemic, caused by SARS-CoV-2, has created an urgent need for novel antiviral agents, as it led to a devastating loss of lives worldwide. In response, numerous vaccines were developed in 2022, with ongoing efforts more candidates. Despite significant progress, reports vaccine-related issues and side effects have emerged. effectiveness been challenged new viral variants, lack well-designed vivo experiments, randomised controlled trials. Currently, no clinically approved medications exist treating COVID-19. However, few broad-spectrum drugs shown promising outcomes clinical studies. Many scientists believe that natural compounds derived from herbal medicines mushrooms could offer substantial benefits patients. Ganoderma, known its traditional use promoting health longevity, rich history therapeutic applications dietary supplementation. Numerous epidemiological studies demonstrated Ganoderma derivatives can enhance innate adaptive immune responses against various pathogens, including viruses, laboratory settings living organisms. Therefore, the secondary metabolites such triterpenoids, polysaccharides, glycoproteins, hold potential developing drugs. These mechanisms, inhibition replication, modulation responses, direct virucidal effects. Given search effective treatments COVID-19, bioactive stand out candidates further research development. Their multifaceted mechanisms make them suitable exploration agents potentially contributing enhancing existing treatments.

Language: Английский

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Prospect of herbal medication as prevention against COVID variants

Journal of King Saud University - Science, Journal Year: 2022, Volume and Issue: 35(1), P. 102360 - 102360

Published: Oct. 11, 2022

Personal immunity frolicked an essential role in combating COVID-19 impacts on human health individually and collectively community. Literature represented the fact about food or nutritional supplements are certified to protect against diseases; this was reason behind public trust certain plants other commercial products boost up coronavirus disease. Present study conducted observe attitude of common towards natural herbs treating various diseases assess possible potential herbal medication prevention negative different variants at clinic named "Pakistan Matab". Results concluded that most patients (About 80%) avoided testing even experiencing major symptoms they preferred medication. Patients who died by were also like liver Kideny malfunctioning; old age another significant factor case. About 90% COVID symptomatic 10% carrying during observational period clinic. Study visited clinic, have a faith with 60% favor vaccine allopathic combination treatment. investigated only for one type variant use medicines could be better option variants.

Language: Английский

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Ginger - Cultivation and Use

IntechOpen eBooks, Journal Year: 2022, Volume and Issue: unknown

Published: Oct. 13, 2022

Zingiber officinale, often referred to as ginger, is the scientific name for blooming plant-producing underground rhizome. The rhizome may be used both in kitchen and traditional forms of healing. It a herbaceous perennial that survive many years generates annual pseudostems (false stems made coiled bases leaves) reach heights around one meter, bare, thin leaf blades. Antioxidants bioactive compounds are present ginger. This book explores recent developments ginger production biochemical research against background current impending environmental change.

Language: Английский

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Herbal products and food supplements consumption and belief during the COVID-19 pandemic: A study in Java Island, Indonesia

Jurnal Agercolere, Journal Year: 2022, Volume and Issue: 4(1), P. 1 - 13

Published: May 21, 2022

The popularity of herbal products in Indonesia during the COVID-19 pandemic has risen recently. It is believed to be preventive measures lower probability infection and boost immunity. This study explored knowledge Java Island population about their belief supplements consumption for prevention infection. A total 485 respondents participated this research. About 84.7% (n = 411) participants claimed that they had used or before pandemic. Recommendations from friends relatives (51.1%, n 248) were main reason consume supplements. Multivitamins (19.6%, 95) most commonly chosen supplement increase immunity reduce chance governments are suggested provide more evidence-based campaigns awareness use ensure patient safety.

Language: Английский

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Paving New Roads Using Allium sativum as a Repurposed Drug and Analyzing its Antiviral Action Using Artificial Intelligence Technology

Deleted Journal, Journal Year: 2023, Volume and Issue: 21(1)

Published: Jan. 21, 2023

Context: The whole universe is facing a coronavirus catastrophe, and prompt treatment for the health crisis primarily significant. primary way to improve conditions in this battle boost our immunity alter diet patterns. A common bulb veggie used flavor cuisine garlic. Compounds plant that are physiologically active present, contributing its pharmacological characteristics. Among several food items with nutritional value improvement, garlic stood predominant more resourceful natural antibiotic broad spectrum of antiviral potency against diverse viruses. However, earlier reports have depicted efficacy variety viral illnesses. Nonetheless, there no information on activities underlying molecular mechanisms. Objectives: bioactive compounds include organosulfur (allicin alliin) flavonoid (quercetin) compounds. These shown immunomodulatory effects inhibited attachment angiotensin-converting enzyme 2 (ACE2) receptor Mpro severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Further, we discussed contradictory impacts as preventive measure novel coronavirus. Method: GC/MS analysis revealed 18 chemicals, including 17 Using docking technique, report first time inhibitory effect under-consideration host ACE2 protein human body, providing crucial foundation understanding individual compound resistance main protease SARS-CoV-2. Allyl disulfide allyl trisulfide, which make up majority garlic, exhibit most potent activity. Results: Conventional medicine has proven efficiency from ancient times. Currently, article's prime spotlight was activity Allium sativum relegation load further highlighted artificial intelligence technology study allicin SARS-CoV-2 reveal efficacy. Conclusions: COVID-19 pandemic triggered interest among researchers conduct future research clinical trials before releasing salutary remedies deadly malady.

Language: Английский

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Perceptions and Patterns of Dietary Supplements’ Use during COVID-19 among Undergraduate Female Students in Saudi Arabia

Nutrients, Journal Year: 2022, Volume and Issue: 14(18), P. 3728 - 3728

Published: Sept. 9, 2022

(1) Background: During the COVID-19 pandemic, use of Dietary Supplements (DSs) has increased for health promotion purposes. Few data records were found on safe DSs among university students in Saudi Arabia, during COVID-19. This study aimed to assess perceptions and patterns at a selected female university. (2) Methods: A descriptive cross-section design was used. convenient sample undergraduate (n = 651) recruited via email, fill an online validated questionnaire: The nutrition intake Data analyzed using inferential statistics. (3) Results: Among 509 who did not have chronic diseases, 85% them had taken DSs. About 35.5% changed their dietary habits since beginning COVID-19, but 78.6% thought that they needed improve immunity by taking Half 51.2% believed healthy may reduce chance being infected with most used vitamin C (84.3%), followed honey (65.3%), D (47.7%). At top students' references personal judgment or previous knowledge benefits (27.3%). (4) Conclusion: usage impacted pandemic. Taking without doctor's prescription lead several complications. users should be educated effectively about proper as external supplementation.

Language: Английский

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Association of Healthy Diet with Recovery Time from COVID-19: Results from a Nationwide Cross-Sectional Study

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(16), P. 8248 - 8248

Published: Aug. 4, 2021

The world is still in need of an effective therapy to treat coronavirus disease-19 (COVID-19). This cross-sectional study was conducted on COVID-19 survivors Saudi Arabia investigate the influence a healthy diet recovery time from COVID-19. A questionnaire developed assess participants' dietary habits, based 2015 Dutch food-based guidelines. total 738 participated study, whom 237 (32.1%) were hospitalized for treatment while 501 (76.9%) not hospitalized, and 320 (43.4%) females 418 (56.6%) males. Overall, no significant difference noted score between males females; however, this significantly lower Saudis compared non-Saudis. Among non-hospitalized patients, eating more associated with shorter duration (p < 0.05) affected by gender (15.8 ± 9.3 male vs. 12.1 8.9 female; p 0.001) marital status (12.1 8.4 singles 13.7 married 16.1 11.8 divorced; 0.05). In contrast, correlation found age or BMI. However, further studies are needed thoroughly relationship

Language: Английский

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