Open Medicine,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: Jan. 1, 2024
Abstract
Objectives
This
narrative
review
aims
to
update
the
current
evidence
and
offer
insight
into
new
non-invasive
ultrasound
techniques
used
early
identify
degenerative
vascular
changes
in
subjects
with
periodontitis
investigate
if
these
methodologies
could
be
useful
subclinical
cardiovascular
disease
(CVD)
dysfunction
patients
monitor
CVD
risk
after
periodontal
treatment.
Methods
Studies
examining
assessment
of
endothelial
function
through
latest
were
analyzed.
Systematic
reviews,
observational
studies,
clinical
trials
English
language
identified
using
PubMed,
Web
Science,
Google
Scholar
databases
key
search
terms
such
as
“periodontitis,”
“endothelial
(ED),”
“arterial
stiffness,”
“periodontal
therapy.”
Results
Several
mechanisms
are
involved
association
between
CVD.
The
players
bacteria
their
toxins,
which
can
enter
circulation
infiltrate
blood
vessel
walls.
increase
proinflammatory
molecules
interleukins
chemokines,
c-reactive
protein,
fibrinogen,
oxidative
stress
also
plays
a
decisive
role.
In
addition,
an
parameters
ED,
arterial
stiffness,
atherosclerosis,
carotid
intima-media
thickness,
pulse
wave
velocity,
flow-mediated
dilatation,
has
been
shown
patients.
Conclusions
literature
today
agrees
on
positive
role
therapy
systemic
inflammatory
indices
outcomes.
Hopefully,
extended
provide
comprehensive
understanding
CVD-periodontitis
link
from
perspective
personalized
medicine
approach
periodontology.
Endocrine Reviews,
Journal Year:
2024,
Volume and Issue:
46(1), P. 80 - 148
Published: Sept. 6, 2024
Abstract
Treatment
of
classic
congenital
adrenal
hyperplasia
(CAH)
is
directed
at
replacing
deficient
hormones
and
reducing
androgen
excess.
However,
even
in
the
era
early
diagnosis
lifelong
hormonal
substitution,
presence
CAH
still
associated
with
numerous
complications
also
increased
mortality.
The
aim
this
article
was
to
create
an
authoritative
balanced
review
concerning
cardiometabolic
risk
patients
CAH.
authors
searched
all
major
databases
scanned
reference
lists
potentially
eligible
articles
find
relevant
articles.
compared
that
other
forms
insufficiency.
reviewed
articles,
most
which
were
published
recently,
provided
conflicting
results,
can
be
partially
explained
by
differences
inclusion
criteria
treatment,
small
sample
sizes,
gene–environment
interactions.
many
studies
showed
weight
gain,
worsening
insulin
sensitivity,
high
blood
pressure,
endothelial
dysfunction,
atherosclerotic
changes
vascular
wall,
left
ventricular
diastolic
dysfunction.
These
more
consistently
reported
than
nonclassic
part
related
functional
abnormalities
disorder
and/or
impact
overtreatment
undertreatment.
An
analysis
available
suggests
individuals
are
risk.
Excess
cardiovascular
metabolic
morbidity
likely
multifactorial,
glucocorticoid
overtreatment,
imperfect
hormone
replacement
therapy,
excess,
adrenomedullary
failure.
Cardiometabolic
effects
new
therapeutic
approaches
require
future
targeted
studies.
Diagnostics,
Journal Year:
2024,
Volume and Issue:
14(22), P. 2499 - 2499
Published: Nov. 8, 2024
Flow-mediated
dilation
(FMD)
is
a
noninvasive
method
to
evaluate
vascular
endothelial
function,
which
manifests
the
inflammatory
response,
cell
proliferation,
and
autoregulation.
Since
FMD
assesses
commonly
in
brachial
artery
by
ultrasound,
compared
other
invasive
methods
such
as
optical
coherence
tomography
(OCT)
intravascular
ultrasound
(IVUS),
it
widely
used
function
allows
serial
assessment.
In
this
review,
we
present
currently
accepted
mechanisms
of
measurement
with
studies
applied
current
clinical
practice
using
FMD.
After
all,
association
cardiovascular
diseases
substance,
so
introduce
related
disease
diabetes,
hyperlipidemia,
chronic
kidney
disease,
coronary
peripheral
disease.
addition,
pregnancy
COVID-19
were
also
inspected.
Yet,
examination
not
endorsed
prevention
measure,
for
lack
clear
standardized
value
methodology.
Still,
many
recommend
practicable
would
be
better
prognostic
prognosis
future
research.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
14(1), P. 53 - 53
Published: Dec. 26, 2024
Cardiovascular
diseases
(CVDs)
are
one
of
the
most
critical
public
health
problems
in
contemporary
world
because
they
leading
cause
morbidity
and
mortality.
Diabetes
mellitus
(DM)
is
substantial
risk
factors
for
developing
CVDs.
Glycated
hemoglobin
a
product
non-enzymatic
glycation
present
erythrocytes.
The
determination
percentage
glycated
(HbA1c)
commonly
used
clinical
practice
to
assess
glycemic
control
patients
diagnosed
with
DM.
This
method
much
more
informative
than
repeated
blood
glucose
tests,
HbA1c
value
reflects
degree
over
last
three
months.
It
is,
therefore,
not
surprising
that
correlates
presence
severity
diabetes
complications,
including
CVDs,
population
diabetic
patients.
purpose
this
publication
was
results
literature
review
on
relationship
between
people
without
DM,
subclinical
cardiovascular
dysfunction,
clinically
overt
important
tools
dysfunction
included
measurement
intima-media
thickness
(IMT),
especially
carotid
IMT
(cIMT),
arterial
stiffness
assessment
by
pulse
wave
velocity
(PWV),
ankle–brachial
index
(ABI).
According
studies
cited
review,
it
can
be
concluded
there
certain
relationships
HbA1c,
CVDs
such
as
coronary
heart
disease,
cerebrovascular
chronic
lower
extremity
ischemia
non-diabetic
worth
noting,
however,
conducted
so
far
area
fully
unambiguous.
Further
needed
better
understand
influence
additional
