Role of plant secondary metabolites in defence and transcriptional regulation in response to biotic stress

Plant Stress, Journal Year: 2023, Volume and Issue: 8, P. 100154 - 100154

Published: April 3, 2023

Secondary metabolites in plants have been recognized as a novel basis of potential bio-pesticides, paving the way for their use sustainable agriculture. Plant secondary pivotal roles plant-pathogen interactions. Some important are terpenoids, flavanols, flavones, etc., stress-inducible phytochemicals playing an role plant immune response development. Pathogen enters into host cell, multiply and utilise biological mechanism plants, causing hazard to world food assembly. Under stressed circumstances, evolve powerful intricate system growth defensive action. On other hand, transcription factors (TFs) assist counter adverse environments by acting mediators stress signal regulating stress-responsive gene expression. The transcriptional post-transcriptional manipulation is capable aid molecular breeding genetic modification meant improved metabolite synthesis. Although presence numerous has established life, very slight known about interaction with pathogens specific mechanisms involved leading immunity. Chemical pesticides wreaking havoc on our environment. As consequence, environmental-friendly alternatives disease management, like plant-based metabolites, should be explored. In this appraisal, we reviewed relation pathogens, contribution innate immunity, action, regulation TFs combating infections eco-friendly approach.

Language: Английский

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Plant defense against fungal pathogens by antagonistic fungi with Trichoderma in focus

Microbial Pathogenesis, Journal Year: 2019, Volume and Issue: 129, P. 7 - 18

Published: Jan. 30, 2019

Language: Английский

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Role of environmental factors in shaping the soil microbiome

Environmental Science and Pollution Research, Journal Year: 2020, Volume and Issue: 27(33), P. 41225 - 41247

Published: Aug. 23, 2020

Language: Английский

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The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus

Proceedings of the National Academy of Sciences, Journal Year: 2020, Volume and Issue: 117(11), P. 6003 - 6013

Published: Feb. 28, 2020

Filamentous fungi, such as Neurospora crassa , are very efficient in deconstructing plant biomass by the secretion of an arsenal cell wall-degrading enzymes, remodeling metabolism to accommodate production secreted and enabling transport intracellular utilization components. Although a number enzymes transcriptional regulators involved have been identified, how filamentous fungi sense integrate nutritional information encoded wall into regulatory hierarchy for optimal complex carbon sources is not understood. Here, we performed profiling N. on 40 different sources, including biomass, provide data simple carbohydrates. From these data, identified factors characterized one (PDR-2) associated with pectin pectin/hemicellulose (ARA-1). Using vitro DNA affinity purification sequencing (DAP-seq), direct targets transcription regulating genes encoding enzymes. In particular, our clarified role factor VIB-1 regulation nutrient scavenging revealed major catabolite repressor CRE-1 expression facilitator transporter genes. These contribute more complete understanding cross talk between their target genes, which sensing global level.

Language: Английский

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Molecular basis and regulation of pathogenicity and patulin biosynthesis in Penicillium expansum

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2020, Volume and Issue: 19(6), P. 3416 - 3438

Published: Aug. 28, 2020

Abstract Penicillium expansum is a necrotrophic plant pathogen with wide range of fruit hosts. It causes blue mold rot during storage, transport, and sale, resulting in huge economic losses to the industry. Moreover, this also main producer patulin, toxic secondary metabolite that contaminates fruit‐derived products impairs human health. Therefore, understanding molecular basis pathogenicity patulin biosynthesis fungal has important scientific significance plays an guiding role research development new control technologies. Here, we comprehensively summarize recent progress, particularly regarding aspects pathogenicity, biosynthesis, related regulatory mechanisms, as well technologies for

Language: Английский

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Engineered microbial host selection for value-added bioproducts from lignocellulose

Biotechnology Advances, Journal Year: 2019, Volume and Issue: 37(6), P. 107347 - 107347

Published: Feb. 13, 2019

Language: Английский

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Transcription factor control of virulence in phytopathogenic fungi

Molecular Plant Pathology, Journal Year: 2021, Volume and Issue: 22(7), P. 858 - 881

Published: May 11, 2021

Plant-pathogenic fungi are a significant threat to economic and food security worldwide. Novel protection strategies required therefore it is critical we understand the mechanisms by which these pathogens cause disease. Virulence factors pathogenicity genes have been identified, but in many cases their roles remain elusive. It becoming increasingly clear that gene regulation vital enable plant infection transcription play an essential role. Efforts determine regulatory functions plant-pathogenic expanded since annotation of fungal genomes revealed ubiquity from broad range families. This review establishes significance as elements provides systematic overview those functionally characterized. Detailed analysis provided on regulators well-characterized families controlling various aspects metabolism, development, stress tolerance, production virulence such effectors secondary metabolites. covers conserved with either specialized or nonspecialized roles, well recently identified targeting key pathways. Fundamental knowledge factor avenues identify novel improve our understanding networks linked pathogen evolution, while can themselves be specifically targeted for disease control. Areas requiring further insight regarding molecular and/or specific classes direction future investigation presented.

Language: Английский

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From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi

Biotechnology Advances, Journal Year: 2021, Volume and Issue: 50, P. 107770 - 107770

Published: May 11, 2021

Language: Английский

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Regulation of Conidiogenesis in Aspergillus flavus

Cells, Journal Year: 2022, Volume and Issue: 11(18), P. 2796 - 2796

Published: Sept. 7, 2022

Aspergillus flavus is a representative fungal species in the section Flavi and has been used as model system to gain insights into development toxin production. A. several adverse effects on humans, including production of most carcinogenic mycotoxin aflatoxins causing aspergillosis immune-compromised patients. In addition, infection crops results economic losses due yield loss aflatoxin contamination. saprophytic fungus that disperses ecosystem mainly by producing asexual spores (conidia), which also provide long-term survival harsh environmental conditions. Conidia are composed rodlet layer, cell wall, melanin produced from an specialized structure called conidiophore. The conidiophores tightly regulated various regulators, central regulatory cascade BrlA-AbaA-WetA, fungi-specific velvet upstream developmental repressors. this review, we summarize findings series recent studies related for better understanding other Flavi.

Language: Английский

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A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae

Communications Biology, Journal Year: 2025, Volume and Issue: 8(1)

Published: Jan. 28, 2025

Carbon catabolite repression (CCR) and de-repression (CCDR) are critical for fungal development pathogenicity, yet the underlying regulatory mechanisms remain poorly understood in pathogenic fungi. Here, we identify a serine/threonine protein phosphatase catalytic subunit, Pp4c, as essential growth, conidiation, virulence, utilization of carbohydrates lipids Magnaporthe oryzae. We demonstrate that 4 complex (Pp4c Smek1 subunits), AMP-activated kinase (AMPK) Snf1, transcriptional regulators CreA (repressor) Crf1 (activator) collaboratively regulate non-preferred carbon sources. Protein interaction phosphorylation analyses reveal under glucose-rich conditions, Snf1 directly status Crf1. In contrast, l-arabinose-rich indirectly modulates dephosphorylation these transcription factors via Pp4c Smek1. Phosphorylation-mediated activation or inactivation drives CCR CCDR, thereby governing metabolism sources derived from plant cell walls contributing to pathogenicity. These findings provide deep insights into regulation emphasizing their significance pathogenicity phytopathogenic The complex, kinase, control rice blast fungus

Language: Английский

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