Application of Nanomaterials in Biomedical Imaging and Cancer Therapy

Nanomaterials, Journal Year: 2020, Volume and Issue: 10(9), P. 1700 - 1700

Published: Aug. 29, 2020

Nanomaterials, such as nanoparticles, nanorods, nanosphere, nanoshells, and nanostars, are very commonly used in biomedical imaging cancer therapy. They make excellent drug carriers, contrast agents, photothermal photoacoustic radiation dose enhancers, among other applications. Recent advances nanotechnology have led to the use of nanomaterials many areas functional imaging, therapy, synergistic combinational platforms. This review will systematically explore various applications The medical modalities include magnetic resonance computed tomography, positron emission single photon computerized optical ultrasound, imaging. Various therapeutic methods also be included, including photodynamic chemotherapy, immunotherapy. covers theranostics, which same agent diagnosis includes recent multimodality image-guided combination We found that continuous synthesis design novel enhance future development However, more resources should available examine side effects cell toxicity when using humans.

Language: Английский

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Interactions of Nanoparticles and Biosystems: Microenvironment of Nanoparticles and Biomolecules in Nanomedicine

Nanomaterials, Journal Year: 2019, Volume and Issue: 9(10), P. 1365 - 1365

Published: Sept. 24, 2019

Nanotechnology is a multidisciplinary science covering matters involving the nanoscale level that being developed for great variety of applications. Nanomedicine one these attractive and challenging uses focused on employment nanomaterials in medical applications such as drug delivery. However, handling nanometric systems require defining specific parameters to establish possible advantages disadvantages This review presents fundamental factors nanoparticles its microenvironment must be considered make an appropriate design applications, mainly: (i) Interactions between their biological environment, (ii) interaction mechanisms, (iii) physicochemical properties nanoparticles. On other hand, repercussions control, alter modify biomedical Additionally, we briefly report implications nanomedicine precision medicine, provide perspectives immunotherapy, which opening novel immune-oncology.

Language: Английский

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A Critical Review of the Use of Surfactant-Coated Nanoparticles in Nanomedicine and Food Nanotechnology

International Journal of Nanomedicine, Journal Year: 2021, Volume and Issue: Volume 16, P. 3937 - 3999

Published: June 1, 2021

Abstract: Surfactants, whose existence has been recognized as early 2800 BC, have had a long history with the development of human civilization. With rapid nanotechnology in latter half 20th century, breakthroughs nanomedicine and food using nanoparticles remarkable, new applications developed. The technology surfactant-coated nanoparticles, which provides functions to for use fields nanotechnology, is attracting lot attention basic research industry. This review systematically describes these “surfactant-coated nanoparticles” through various sections order: 1) surfactants, 2) application 3) nanomedicine, 4) nanotechnology. Furthermore, current progress problems recent reports discussed. Keywords: drug delivery system, targeting, science, packaging, nonionic safety assessment

Language: Английский

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Polymeric micelles and cancer therapy: an ingenious multimodal tumor-targeted drug delivery system

Drug Delivery and Translational Research, Journal Year: 2022, Volume and Issue: 13(1), P. 135 - 163

Published: June 21, 2022

Language: Английский

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Nanoparticles: A New Approach to Upgrade Cancer Diagnosis and Treatment

Nanoscale Research Letters, Journal Year: 2021, Volume and Issue: 16(1)

Published: May 20, 2021

Abstract Traditional cancer therapeutics have been criticized due to various adverse effects and insufficient damage targeted tumors. The breakthrough of nanoparticles provides a novel approach for upgrading traditional treatments diagnosis. Actually, can not only solve the shortcomings diagnosis treatment, but also create brand-new perspectives cutting-edge devices tumor treatment. However, most research about stays in vivo vitro stage, few clinical researches reported. In this review, we first summarize current applications After that, propose challenges that hinder NPs provide feasible solutions combination with updated literature last two years. At end, will our opinions on future developments

Language: Английский

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Treasure on the Earth—Gold Nanoparticles and Their Biomedical Applications

Materials, Journal Year: 2022, Volume and Issue: 15(9), P. 3355 - 3355

Published: May 7, 2022

Recent advances in the synthesis of metal nanoparticles (NPs) have led to tremendous expansion their potential applications different fields, ranging from healthcare research microelectronics and food packaging. Among approaches for exploiting nanotechnology medicine, gold nanomaterials particular been found as most promising due unique advantages, such sensing, image enhancement, delivery agents. Although, first scientific article on was presented 1857 by Faraday, during last few years, progress manufacturing these has taken an enormous step forward. Due nanoscale counterparts gold, which exhibit distinct properties functionality compared bulk material, stand out, particular, therapy, imaging, detection, diagnostics, precise drug delivery. This review summarizes current state-of-the-art knowledge terms biomedical nanoparticles. The application AuNPs following aspects are discussed: (i) imaging diagnosing specific target; (ii) treatment therapies using AuNPs; (iii) systems with a carrier. medical here we either consider contrast agent computed tomography (CT), or particle used optical instead fluorophores. Moreover, nontoxic feature, gadolinium-based agents magnetic resonance shown. tunable size, shape, make them great carriers targeted Therefore, here, summarize gold-based nanodrugs that FDA approved. Finally, various treat diseases discussed, i.e., photothermal photodynamic immunotherapy.

Language: Английский

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Hybrid Nanomaterials for Cancer Immunotherapy

Advanced Science, Journal Year: 2022, Volume and Issue: 10(6)

Published: Dec. 25, 2022

Abstract Nano‐immunotherapy has been recognized as a highly promising strategy for cancer treatment in recent decades, which combines nanotechnology and immunotherapy to combat against tumors. Hybrid nanomaterials consisting of at least two constituents with distinct compositions properties, usually organic inorganic, have engineered integrated functions enormous potential boosting immunotherapy. This review provides summary hybrid reported immunotherapy, including nanoscale metal–organic frameworks, metal–phenolic networks, mesoporous organosilica nanoparticles, metallofullerene nanomaterials, polymer–lipid, biomacromolecule‐based nanomaterials. The combination chemotherapy, chemodynamic therapy, radiotherapy, radiodynamic photothermal photodynamic sonodynamic therapy based on is also discussed. Finally, the current challenges prospects designing their application are outlined.

Language: Английский

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Nanoparticles in Cancer Diagnosis and Treatment

Materials, Journal Year: 2023, Volume and Issue: 16(15), P. 5354 - 5354

Published: July 30, 2023

The use of tailored medication delivery in cancer treatment has the potential to increase efficacy while decreasing unfavourable side effects. For researchers looking improve clinical outcomes, chemotherapy for continues be most challenging topic. Cancer is one worst illnesses despite limits current therapies. New anticancer medications are therefore required treat cancer. Nanotechnology revolutionized medical research with new and improved materials biomedical applications, a particular focus on therapy diagnostics. In research, application metal nanoparticles as substitute drugs growing. Metals exhibit inherent or surface-induced properties, making metallic extremely useful. development proceeding rapidly many directions, offering alternative therapeutic strategies improving outcomes treatments. This review aimed present commonly used applications.

Language: Английский

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Theranostic applications of selenium nanomedicines against lung cancer

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: March 20, 2023

Abstract The incidence and mortality rates of lung cancer are among the highest in world. Traditional treatment methods include surgery, chemotherapy, radiotherapy. Although rapid progress has been achieved past decade, limitations remain. It is therefore imperative to identify safer more effective therapeutic methods, research currently being conducted efficient less harmful drugs. In recent years, discovery antitumor drugs based on essential trace element selenium (Se) provided good prospects for treatments. particular, compared inorganic Se (Inorg-Se) organic (Org-Se), nanomedicine (Se nanoparticles; SeNPs) shows much higher bioavailability antioxidant activity lower toxicity. SeNPs can also be used as a drug delivery carrier better regulate protein DNA biosynthesis kinase C activity, thus playing role inhibiting cell proliferation. effectively activate antigen-presenting cells stimulate immunity, exert regulatory effects innate enhance immunotherapy. This review summarizes application Se-based species materials diagnosis, including fluorescence, MR, CT, photoacoustic imaging other diagnostic well treatments, direct killing, radiosensitization, chemotherapeutic sensitization, photothermodynamics, enhanced addition, challenges examined, their forecasted future clinical applications sustainable development. Graphical

Language: Английский

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Nanoparticles in cancer diagnosis and treatment: Progress, challenges, and opportunities

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105599 - 105599

Published: March 26, 2024

Despite considerable progress in patient care, the global incidence of various cancer types continues to rise. Developing safer and more efficient anti-cancer treatment approaches are great interest. In recent decades, nanotechnology has emerged as a promising innovative medical approach for diagnosis treatment. However, nanomedicine advances, it is important understand address challenges. Herein, we identify gaps current understanding effectiveness on clinical outcomes provide an outlook improved application medicine. We discuss use different nanoparticles therapy impact efficiency existing treatments, such chemotherapeutic, anti-angiogenic, immunotherapeutic drugs, radiotherapy. Additionally, update status trials nanoparticle-based treatments provided.

Language: Английский

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