Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives

Food Chemistry X, Journal Year: 2022, Volume and Issue: 13, P. 100217 - 100217

Published: Jan. 19, 2022

Essential oils (EOs) are volatile and concentrated liquids extracted from different parts of plants. Bioactive compounds found in EOs, especially terpenes terpenoids possess a wide range biological activities including anticancer, antimicrobial, anti-inflammatory, antioxidant, antiallergic. Available literature confirms that EOs exhibit antimicrobial food preservative properties considered as real potential application industry. Hence, the purpose this review is to present an overview current knowledge for pharmaceutical medical industries well their preservatives

Language: Английский

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Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms

Pharmacological Research, Journal Year: 2020, Volume and Issue: 163, P. 105224 - 105224

Published: Sept. 29, 2020

Language: Английский

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Forest Volatile Organic Compounds and Their Effects on Human Health: A State-of-the-Art Review

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(18), P. 6506 - 6506

Published: Sept. 7, 2020

The aim of this research work is to analyze the chemistry and diversity forest VOCs (volatile organic compounds) outline their evidence-based effects on health. This was designed as a narrative overview scientific literature. Inhaling like limonene pinene can result in useful antioxidant anti-inflammatory airways, pharmacological activity some terpenes absorbed through inhalation may be also beneficial promote brain functions by decreasing mental fatigue, inducing relaxation, improving cognitive performance mood. tree composition markedly influence concentration specific air, which exhibits cyclic diurnal variations. Moreover, psychological physiological visiting cannot solely attributed VOC but are due global integrated stimulation five senses, induced all characteristics natural environment, with visual component probably playing fundamental role overall effect. Globally, these findings have implications for individual wellbeing, public health, landscape design. Further clinical environmental studies advised, since majority existing evidence derived from laboratory findings.

Language: Английский

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Therapeutic Applications of Terpenes on Inflammatory Diseases

Frontiers in Pharmacology, Journal Year: 2021, Volume and Issue: 12

Published: Aug. 13, 2021

In the last decades, search for natural products with biological applications as alternative treatments several inflammatory diseases has increased. this respect, terpenes are a family of organic compounds obtained mainly from plants and trees, such tea, cannabis, thyme, citrus fruits like lemon or mandarin. These molecules present attractive properties analgesic anticonvulsant activities. Furthermore, studies have demonstrated that certain could reduce inflammation symptoms by decreasing release pro-inflammatory cytokines example, nuclear transcription factor-kappa B, interleukin 1, tumor necrosis factor-alpha. Thus, due to various anti-inflammatory drugs provoking side effects, analysis novel therapeutics attractive. review, terpenes’ chemical structure their mechanisms in functions addressed. Additionally, we general recent investigations about an treatment diseases. focus on terpenes-based nanoformulations employed dosages offer global perspective state-of-the-art.

Language: Английский

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Terpenoids in essential oils: Chemistry, classification, and potential impact on human health and industry

Phytomedicine Plus, Journal Year: 2024, Volume and Issue: 4(2), P. 100549 - 100549

Published: March 24, 2024

Terpenoids, present in essential oils (EOs), have gained significant attention due to their diverse pharmacological properties and alignment with the growing global interest natural sustainable products. EOs, derived from various plants, shown promise antimicrobial, anti-inflammatory, antioxidant, other valuable applications. This comprehensive review aims elucidate chemistry roles of terpenoids covering classification, extraction techniques, potential pharmaceutical We delve into functions human immune system, impact on health, contributions environmental sustainability. The synthesizes existing literature, categorizing distinct classes, including monoterpenoids, sesquiterpenoids, diterpenoids, sesterterpenoids, triterpenoids. explore purification methods, such as steam distillation, solvent extraction, chromatography. Additionally, we discuss terpenoids, anticancer activities. Terpenoids EOs exhibit potent antimicrobial antioxidant activities, making them pivotal plant disease resistance. They also offer therapeutic applications phytomedicine, aromatherapy, beyond, capacity enhance system combat viruses, inflammation, cancer. demonstrated multifaceted benefits, contributing well-being highlights medical treatments everyday life, emphasizing need understand pharmacokinetics efficacy for harnessing full beyond.

Language: Английский

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Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications

Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 284 - 284

Published: Jan. 13, 2025

Essential oils (EOs) are highly valued in the cosmetic and food industries for their diverse properties. However, traditional extraction methods often result low yields, inconsistent compositions, lengthy times, use of potentially harmful solvents. Natural deep eutectic solvents (NADES) have emerged as promising alternatives, offering advantages such higher efficiency, cost-effectiveness, biodegradability, tunable This review explores application NADES enhancing EO extraction, focusing on current methodologies, key insights, practical applications. It examines factors that influence with NADES, including optimization physicochemical properties, techniques, operational conditions, role sample pretreatment improving efficiency. Additionally, this covers chemical characterization biological activities EOs extracted using NADES. By providing a comprehensive overview, it highlights potential to improve suggests directions future research field.

Language: Английский

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Bacterial terpenome

Natural Product Reports, Journal Year: 2020, Volume and Issue: 38(5), P. 905 - 980

Published: Nov. 10, 2020

We highlight the current state of bacterial terpenome, emphasizing discoveries, structures, biosynthetic pathways, and biological activities these terpenoid natural products.

Language: Английский

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Essential Oils in Livestock: From Health to Food Quality

Antioxidants, Journal Year: 2021, Volume and Issue: 10(2), P. 330 - 330

Published: Feb. 23, 2021

Using plant essential oils (EOs) contributes to the growing number of natural plants’ applications in livestock. Scientific data supporting efficacy EOs as anti-inflammatory, antibacterial and antioxidant molecules accumulates over time; however, cumulative evidence is not always sufficient. properties have been investigated mainly from human perspectives. Still, so far, our review first combine beneficial a One Health approach an animal product quality enhancer, opening new possibilities for their utilization livestock nutrition sectors. We aim compile currently available on main anti-inflammatory effects EOs, whether encapsulated or not, with focus mammary gland inflammation. will also EOs’ activities when given diet food preservative counteract oxidative stress. emphasize vitro vivo ruminal microbiota mechanisms action promote health performance. Given concept DOHaD (Developmental Origin Diseases), supplementing animals early life opens perspectives sector. However, effective evaluation significant safety components required before extending use veterinary medicine.

Language: Английский

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Nature Exposure and Its Effects on Immune System Functioning: A Systematic Review

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(4), P. 1416 - 1416

Published: Feb. 3, 2021

Given the drastic changes in our lifestyles and ecosystems worldwide, potential health effects of natural environments have grown into a highly pervasive topic. Recent scientific findings suggest beneficial from nature exposure on human immune responses. This review aims at providing comprehensive overview literature published immunomodulatory by inhalation substances. A systematic database search was performed SCOPUS PubMed. The quality bias included studies (n = 33) were assessed applying EPHPP (Effective Public Health Practice Project) tool for ARRIVE (Animal Research: Reporting In Vivo Experiments) SYRCLE (Systematic Review Centre Laboratory Animal Experimentation) tools animal studies. synthesis reviewed points to positive immunological parameters; such as anti-inflammatory, anti-allergic, anti-asthmatic or increased NK (natural killer) cell activity. Decreased expression pro-inflammatory molecules, infiltration leukocytes release cytotoxic mediators are outcomes that may serve baseline further However, partially weak study designs evoked uncertainties about outcome reproducibility key questions remain open concerning effect sizes, duration contributions specific vegetation ecosystem types.

Language: Английский

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Lower COVID-19 mortality in Italian forested areas suggests immunoprotection by Mediterranean plants

Environmental Chemistry Letters, Journal Year: 2020, Volume and Issue: 19(1), P. 699 - 710

Published: Aug. 14, 2020

The COVID-19 pandemic has induced dramatic effects on the population of industrialized north Italy, whereas it not heavily affected inhabitants southern regions. This might be explained in part by human exposure to high levels fine particulate matter (PM) air northern thus exacerbating mortality. Since trees mitigate pollution intercepting PM onto plant surfaces and bolster immune system emitting bioactive volatile organic compounds (VOCs), we hypothesize a protective role evergreen forested areas Italy. We compared mortality rate due COVID-19, death number, positivity forest coverage per capita various Italian Hectares prevalence deciduous versus forestal species were also estimated. In silico docking studies potentially found Laurus nobilis L., typical Mediterranean plant, performed search for potential antivirals. that pandemic's severity was generally lower regions, especially those with more than 0.3 hectares capita. lowest rates mainly regions like Molise (0.007%) Basilicata (0.005%) where ratio is higher 0.5 Ha/person. Our findings suggest forests shrubland plants could have protected emission immuno-modulating VOCs provision dietary sources compounds. Moreover, revealed anti-COVID-19 activity laurusides, which are unexplored glycosides from bay laurel. Overall, our results highlight importance nature conservation applications natural

Language: Английский

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