Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(5), P. 1098 - 1098
Published: May 15, 2023
Spermatozoa
are
highly
differentiated
cells
that
produce
reactive
oxygen
species
(ROS)
due
to
aerobic
metabolism.
Below
a
certain
threshold,
ROS
important
in
signal
transduction
pathways
and
cellular
physiological
processes,
whereas
overproduction
damages
spermatozoa.
Sperm
manipulation
preparation
protocols
during
assisted
reproductive
procedures—for
example,
cryopreservation—can
result
excessive
production,
exposing
these
oxidative
damage.
Thus,
antioxidants
relevant
topic
sperm
quality.
This
narrative
review
focuses
on
human
spermatozoa
as
an
vitro
model
study
which
can
be
used
supplement
media.
The
comprises
brief
presentation
of
the
structure,
general
overview
main
items
reduction–oxidation
homeostasis
ambivalent
relationship
between
ROS.
body
paper
deals
with
studies
have
been
test
antioxidant
compounds,
including
natural
extracts.
presence
synergic
effects
different
molecules
could
potentially
lead
more
effective
products
and,
future,
vivo.
Cells,
Journal Year:
2023,
Volume and Issue:
12(9), P. 1322 - 1322
Published: May 5, 2023
Physiologically,
autophagy
is
an
evolutionarily
conserved
and
self-degradative
process
in
cells.
Autophagy
carries
out
normal
physiological
roles
throughout
mammalian
life.
Accumulating
evidence
shows
as
a
mechanism
for
cellular
growth,
development,
differentiation,
survival,
homeostasis.
In
male
reproductive
systems,
spermatogenesis
steroidogenesis
need
balance
between
degradation
energy
supply
to
preserve
metabolic
The
main
of
includes
the
formation
maturation
phagophore,
autophagosome,
autolysosome.
controlled
by
group
autophagy-related
genes
that
form
core
machinery
autophagy.
Three
types
mechanisms
have
been
discovered
cells:
macroautophagy,
microautophagy,
chaperone-mediated
classified
non-selective
or
selective.
Non-selective
macroautophagy
randomly
engulfs
cytoplasmic
components
autophagosomes
are
degraded
lysosomal
enzymes.
While
selective
precisely
identifies
degrades
specific
element,
current
findings
shown
novel
functional
reproduction.
It
has
recognized
dysfunction
can
be
associated
with
infertility.
Overall,
this
review
provides
overview
molecular
basics
summarizes
latest
on
key
role
physiology.
Animals,
Journal Year:
2023,
Volume and Issue:
13(14), P. 2286 - 2286
Published: July 12, 2023
Ram
semen
traits
play
a
significant
role
in
conception
outcomes,
which
turn
may
influence
reproductive
efficiency
and
the
overall
productivity
profitability
of
sheep
enterprises.
Since
hundreds
ewes
be
inseminated
from
single
ejaculate,
it
is
important
to
evaluate
quality
prior
use
breeding
programs.
Given
that
have
been
found
heritable,
genetic
variation
likely
contributes
variability
observed
these
traits.
Identifying
such
variants
could
provide
novel
insights
into
molecular
mechanisms
underlying
Therefore,
this
study
aimed
identify
quantitative
trait
loci
(QTLs)
associated
with
Merino
sheep.
A
genome-wide
association
(GWAS)
was
undertaken
using
4506
collection
records
246
rams
collected
between
January
2002
May
2021.
The
R
package
RepeatABEL
used
perform
GWAS
for
volume,
gross
motility,
concentration,
percent
post-thaw
motility.
total
35
QTLs,
located
on
16
Ovis
aries
autosomes
(OARs),
were
significantly
either
four
study.
89,
95,
33,
73
candidate
genes
identified,
via
modified
Bonferroni,
within
QTLs
respectively.
Among
SORD,
SH2B1,
NT5E
previously
described
spermatogenesis,
spermatozoal
high
Several
identified
potentially
ram
based
existing
evidence
literature.
As
such,
validation
putative
candidates
offer
potential
develop
future
strategies
improve
efficiency.
Furthermore,
are
lowly
heritable
(0.071-0.139),
thus
improved
by
selective
breeding.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(5), P. 1098 - 1098
Published: May 15, 2023
Spermatozoa
are
highly
differentiated
cells
that
produce
reactive
oxygen
species
(ROS)
due
to
aerobic
metabolism.
Below
a
certain
threshold,
ROS
important
in
signal
transduction
pathways
and
cellular
physiological
processes,
whereas
overproduction
damages
spermatozoa.
Sperm
manipulation
preparation
protocols
during
assisted
reproductive
procedures—for
example,
cryopreservation—can
result
excessive
production,
exposing
these
oxidative
damage.
Thus,
antioxidants
relevant
topic
sperm
quality.
This
narrative
review
focuses
on
human
spermatozoa
as
an
vitro
model
study
which
can
be
used
supplement
media.
The
comprises
brief
presentation
of
the
structure,
general
overview
main
items
reduction–oxidation
homeostasis
ambivalent
relationship
between
ROS.
body
paper
deals
with
studies
have
been
test
antioxidant
compounds,
including
natural
extracts.
presence
synergic
effects
different
molecules
could
potentially
lead
more
effective
products
and,
future,
vivo.
