Horticulturae,
Journal Year:
2022,
Volume and Issue:
8(9), P. 828 - 828
Published: Sept. 8, 2022
The
increasing
salinization
of
agricultural
soils
urges
us
to
find
alternative
and
sustainable
farming
systems
in
order
allow
the
exploitation
areas
that
are
otherwise
becoming
less
suitable
for
conventional
crops.
Thanks
their
adaptation
extreme
saline
conditions,
halophytes
promising
plants
resilient
systems,
such
as
intercropping
with
glycophytes,
ameliorate
productivity
soils.
This
research
aimed
evaluate
whether
nutritional
profile
content
some
health-promoting
compounds
edible
portion
Salicornia
europaea
were
influenced
by
its
cultivation
consociation
tomato
plants.
Moreover,
antioxidant,
antibacterial,
anti-inflammatory
properties
S.
studied
characterize
bioactivity.
system
did
not
influence
concentration
nutrients
bioactive
compounds,
except
flavonoids.
antimicrobial
extract
suggested
importance
this
halophyte
animal
human
health.
Foods,
Journal Year:
2024,
Volume and Issue:
13(4), P. 628 - 628
Published: Feb. 19, 2024
Flavonoid
compounds
have
a
variety
of
biological
activities
and
play
an
essential
role
in
preventing
the
occurrence
metabolic
diseases.
However,
many
structurally
similar
flavonoids
are
present
foods
usually
low
concentrations,
which
increases
difficulty
their
isolation
identification.
Therefore,
developing
optimizing
effective
extraction
detection
methods
for
extracting
from
food
is
essential.
In
this
review,
we
review
structure,
classification,
chemical
properties
flavonoids.
The
research
progress
on
recent
years
comprehensively
summarized,
as
application
mathematical
models
experimental
conditions.
results
provide
theoretical
basis
technical
support
detecting
analyzing
high-purity
foods.
Foods,
Journal Year:
2024,
Volume and Issue:
13(15), P. 2441 - 2441
Published: Aug. 2, 2024
Aging
is
a
natural
and
irreversible
process,
affecting
living
organisms
by
negatively
impacting
the
tissues'
cells'
morphology
functionality
consequently
being
responsible
for
aging-related
diseases.
Taking
into
account
actual
preoccupations
of
both
consumers
researchers,
healthy
anti-aging
alternatives
are
intensively
studied
in
order
to
address
such
concerns.
Due
their
functional
features,
plant
flavonoids
can
be
considered
valuable
nutraceuticals.
This
paper
highlights
possibilities
use
extracted
from
various
plants
potential
on
skin,
brain,
heart.
Moreover,
anticarcinogenic,
anti-inflammatory,
anti-diabetic
properties
summarized,
along
with
senescence-associated
mechanisms.
Both
nutraceutical
cosmeceutical
fields
continuously
developing
originating
promising
candidates
obtain
products.
Thus,
bioactive
compounds'
extraction
subsequent
involvement
innovative
product
manufacturing
must
carefully
performed
while
aware
intrinsic
extrinsic
factors
that
may
affect
phytochemicals'
structures,
bioavailability,
health
effects.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: April 10, 2024
The
senescence
of
fruit
is
a
complex
physiological
process,
with
various
cell
types
within
the
pericarp,
making
it
highly
challenging
to
elucidate
their
individual
roles
in
senescence.
In
this
study,
single-cell
expression
atlas
pericarp
pitaya
(Hylocereus
undatus)
constructed,
revealing
exocarp
and
mesocarp
cells
undergoing
most
significant
changes
during
process.
Pseudotime
analysis
establishes
cellular
differentiation
gene
trajectories
Early-stage
oxidative
stress
imbalance
followed
by
activation
resistance
cells,
subsequently
senescence-associated
proteins
accumulate
at
late-stage
central
role
early
response
factor
HuCMB1
unveiled
regulatory
network.
This
study
provides
spatiotemporal
perspective
for
deeper
understanding
dynamic
process
plants.
Biomedicine & Pharmacotherapy,
Journal Year:
2024,
Volume and Issue:
176, P. 116827 - 116827
Published: June 10, 2024
Colorectal
cancer
(CRC)
is
a
major
cause
of
cancer-related
deaths
worldwide,
underscoring
the
importance
understanding
diverse
molecular
and
genetic
underpinnings
CRC
to
improve
its
diagnosis,
prognosis,
treatment.
This
review
delves
into
adenoma-carcinoma-metastasis
model,
emphasizing
"APC-KRAS-TP53"
signature
events
in
development.
categorized
four
consensus
subtypes,
each
characterized
by
unique
alterations
responses
therapy,
illustrating
complexity
heterogeneity.
Furthermore,
we
explore
role
chronic
inflammation
gut
microbiome
progression,
potential
targeting
these
factors
for
prevention
discusses
impact
dietary
carcinogens
lifestyle
critical
early
detection
improving
outcomes,
also
examines
conventional
chemotherapy
options
associated
challenges.
There
significant
focus
on
therapeutic
flavonoids
management,
discussing
various
types
flavonoids,
their
sources,
mechanisms
action,
including
antioxidant
properties,
modulation
cell
signaling
pathways,
effects
cycle
apoptosis.
article
presents
evidence
synergistic
with
therapies
modulating
immune
response,
thereby
offering
new
avenues
We
conclude
multidisciplinary
approach
research
treatment,
incorporating
insights
from
genetic,
molecular,
factors.
Further
needed
preventive
natural
compounds,
such
as
CRC,
need
personalized
targeted
treatment
strategies.
Antioxidants and Redox Signaling,
Journal Year:
2024,
Volume and Issue:
40(7-9), P. 564 - 593
Published: Jan. 22, 2024
Significance:
Currently,
a
large
amount
of
evidence
beneficial
effects
diets
enriched
with
polyphenols
on
various
aspects
health
has
been
accumulated.
These
phytochemicals
have
geroprotective
potential
slowing
down
the
pathological
processes
associated
aging
and
ensuring
longevity.
In
this
study,
comprehensive
analysis
was
conducted
to
determine
adherence
individual
geroprotector
criteria.
Data
from
experimental
models,
clinical
trials,
epidemiological
studies
were
analyzed.
Recent
Advances:
Sixty-two
described
increase
life
span
improve
biomarkers
in
animal
models.
They
act
via
evolutionarily
conserved
molecular
mechanisms,
including
hormesis
maintenance
redox
homeostasis,
epigenetic
regulation,
response
cellular
damage,
metabolic
control,
anti-inflammatory
senolytic
activity.
Epidemiological
suggest
that
certain
for
prevention
treatment
diseases,
cancer,
disorders,
cardiovascular
conditions
humans.
Critical
Issues:
Among
reviewed
phytochemicals,
chlorogenic
acid,
quercetin,
epicatechin,
genistein,
resveratrol,
curcumin
identified
as
compounds
highest
potential.
However,
there
is
lack
unambiguous
information
effectiveness
safety
increasing
span,
preventing
treating
aging-associated
diseases
Future
Directions:
Further
research
needed
fully
understand
considering
their
long-term
consumption,
modification
bioavailability,
complex
interactions
between
different
groups
other
well
individuals
status.
Antioxid.
Redox
Signal.
40,
564–593.
Color
images
are
available
online.
