Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: July 25, 2024
Current
vaccines
against
COVID-19
elicit
immune
responses
that
are
overall
strong
but
wane
rapidly.
As
a
consequence,
the
necessary
booster
shots
have
contributed
to
vaccine
fatigue.
Hence,
would
provide
lasting
protection
needed,
still
unavailable.
Cytomegaloviruses
(CMVs)
and
uniquely
responses.
Used
as
vectors,
they
may
be
attractive
tools
obviate
need
for
boosters.
Therefore,
we
tested
murine
CMV
(MCMV)
vector
in
relevant
preclinical
models
of
immunization
challenge.
We
previously
developed
recombinant
MCMV
expressing
spike
protein
ancestral
SARS-CoV-2
(MCMV
Viruses,
Journal Year:
2023,
Volume and Issue:
15(4), P. 899 - 899
Published: March 31, 2023
The
nasal
mucosa
is
the
main
gateway
for
entry,
replication
and
elimination
of
SARS-CoV-2
virus,
pathogen
that
causes
severe
acute
respiratory
syndrome
(COVID-19).
presence
virus
in
epithelium
damage
to
compromises
mucociliary
clearance.
aim
this
study
was
investigate
viral
antigens
patients
with
a
history
mild
COVID-19
persistent
inflammatory
rhinopathy.
We
evaluated
eight
adults
without
previous
diseases
olfactory
dysfunction
more
than
80
days
after
diagnosis
infection.
Samples
were
collected
via
brushing
middle
concha.
detection
performed
using
immunofluorescence
through
confocal
microscopy.
Viral
detected
all
patients.
Persistent
anosmia
observed
four
Our
findings
suggest
may
lead
rhinopathy
prolonged
or
relapsing
anosmia.
This
sheds
light
on
potential
mechanisms
underlying
symptoms
highlights
importance
monitoring
nasal-related
symptoms.
Frontiers in Cardiovascular Medicine,
Journal Year:
2022,
Volume and Issue:
9
Published: July 27, 2022
Coronavirus
disease
2019
(COVID-19),
which
was
caused
by
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2),
had
already
resulted
in
widespread
epidemics
worldwide
and
millions
of
people's
deaths
since
its
outbreak
2019.
COVID-19
also
been
demonstrated
to
affect
cardiac
function.
However,
the
specific
mechanism
influence
this
damage
were
not
clear
yet.
The
purpose
present
study
provide
a
bibliometric
analysis
current
studies
related
involvement
after
SARS-CoV-2
infection.A
literature
search
performed
on
web
science.
number
type
publications,
countries,
institutional
sources,
journals,
citation
patterns
analyzed.
In
addition,
qualitative
quantitative
evaluations
carried
out
visualize
scientific
achievements
field
using
VOSviewer
software.Web
science
recorded
2,24,097
documents
at
time
data
collection
(May
12,
2022).
A
total
2,025
last.
countries
with
most
published
articles
United
States
America
(USA)
(n
=747,
36.9%),
Italy
=324,
16%),
England
=213,
10.5%).
Although
institutions
that
mainly
from
USA,
top
three
authors
Germany,
England,
Poland.
Frontiers
Cardiovascular
Medicine
journal
(65
3.2%),
followed
ESC
Heart
Failure
(59
2.9%)
Journal
Clinical
(56
2.8%).
We
identified
13,739
authors,
among
Karin
Klingel
Amer
Harky
articles,
Shaobo
Shi
co-cited
often.
There
existed
some
cooperation
between
different
but
scope
limited.
Myocarditis
heart
failure
(HF)
main
research
hotspots
dysfunction
may
be
crucial
prognosis
patients.It
first
publications
COVID-19-associated
disorder.
This
provided
academics
researchers
useful
information
influential
dysfunction.
Cooperation
must
strengthened
myocarditis
HF
during
pandemic.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(4), P. 2212 - 2212
Published: Feb. 12, 2024
The
pandemic
period
due
to
coronavirus
disease
2019
(COVID-19)
revolutionized
all
possible
areas
of
global
health.
Significant
consequences
were
also
related
diverse
extrapulmonary
manifestations
this
pathology.
liver
was
found
be
a
relatively
common
organ,
beyond
the
respiratory
tract,
affected
by
severe
acute
syndrome
coronavirus-2
(SARS-CoV-2).
Multiple
studies
revealed
essential
role
chronic
(CLD)
in
general
outcome
infection.
Present
concerns
field
are
direct
hepatic
caused
COVID-19
and
pre-existing
disorders
as
risk
factors
for
course
Which
mechanism
has
key
phenomenon—previously
existing
disorder
or
failure
SARS-CoV-2—is
still
not
fully
clarified.
Alcoholic
(ALD)
constitutes
another
elucidated
context
Should
toxic
effects
ethanol
already
developed
cirrhosis
its
perceived
causative
triggering
factor
impairment
patients?
In
face
these
discrepancies,
we
decided
summarize
whole
picture
infection,
paying
special
attention
ALD
focusing
on
pathological
pathways
COVID-19,
toxicity
cirrhosis.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 30, 2024
The
emergence
of
severe
acute
respiratory
syndrome
coronavirus-2
(SARS-CoV-2)
and
the
ensuing
COVID-19
pandemic
had
far-reaching
multifaceted
effects
on
global
health.
This
paper
provides
a
comprehensive
overview
physical,
extrapulmonary,
psychological
manifestations
associated
with
COVID-19.
It
highlights
wide-ranging
impact
virus
various
organ
systems,
including
respiratory,
cardiovascular,
renal,
gastrointestinal,
ocular,
dermatologic,
nervous
systems.
Additionally,
it
explores
complex
connections
between
infection
neuropsychiatric
symptoms,
shedding
light
potential
underlying
mechanisms.
also
delves
into
phenomenon
"long
COVID,"
condition
characterized
by
persistent
symptoms
extending
well
beyond
disease's
phase.
discusses
diverse
often
debilitating
that
individuals
long
COVID
may
experience,
encompassing
cognitive,
aspects.
complexity
variability
underscore
challenges
poses
to
healthcare
professionals
importance
ongoing
research
understand
its
Furthermore,
touches
current
state
knowledge
regarding
aetiology
approaches
symptom
management
treatment.
While
definitive
cure
remains
elusive,
efforts
are
underway
alleviate
burden
through
pharmacological
interventions,
physical
therapy,
cognitive-behavioral
support
networks.
comprehensively
COVID-19's
effects,
emphasizing
need
for
holistic
interdisciplinary
approach
understanding
managing
this
health
challenge.
Ongoing
collaborative
essential
in
addressing
evolving
nature
aftermath.
Clinics and Practice,
Journal Year:
2023,
Volume and Issue:
13(6), P. 1319 - 1330
Published: Oct. 26, 2023
The
COVID-19
pandemic
due
to
the
SARS-CoV-2
coronavirus
showed
acute
and
prolonged
effects
on
human
health.
In
addition,
over
past
four
years,
there
has
been
a
tremendous
surge
in
COVID-19-related
scientific
publications,
as
shown
by
bibliometric
scientometric
studies.
However,
such
analysis
of
literature
is
lacking
area
male
reproduction.
current
study
analyzes
publication
characteristics
articles
related
reproduction
infection.
We
used
Scopus
database
analyze
data
(the
number
journals,
countries,
type
documents,
subject
area)
reproductive
research.
Our
search
identified
345
Most
were
published
USA
(n
=
72),
Italy
55),
China
51).
Such
research
was
mainly
focused
around
medicine
(57.1%),
followed
biochemistry,
genetics,
molecular
biology
(25.7%).
Also,
reproduction,
only
37.1%
128)
contributed
towards
original
research,
whereas
52.8%
182)
review
editorials
focusing
more
sexual
dysfunction
than
infertility.
small
studies
warrants
significant
increase
which
required
decipher
mechanism(s)
underlying
infection-associated
impairment
function.
Highlights in Science Engineering and Technology,
Journal Year:
2023,
Volume and Issue:
36, P. 1186 - 1192
Published: March 21, 2023
The
SARS-CoV-2
virus
has
the
potential
to
infect
a
number
of
organs
and
systems
varying
degrees.
Human
immune
system
will
respond
it
within
few
days
with
symptoms
such
as
fever,
cough
trouble
breathing.
Despite
fact
that
COVID-19
is
considered
disease
mostly
affects
lungs,
may
also
have
an
impact
on
kidneys,
brain
heart.
Many
individuals
mistakenly
think
COVID
temporary
illness.
However
scientific
research
shown
organ
damage
can
result
in
both
short-term
long-term
health
issues
continue
for
up
six
months
irreversible
body.
However,
clinically,
human
body
not
completely
clear
about
body,
especially
after
recovery,
still
be
harassed
by
some
symptoms.This
paper
aims
discuss
how
coronavirus
influences
Cureus,
Journal Year:
2023,
Volume and Issue:
unknown
Published: April 24, 2023
As
we
enter
the
fourth
year
of
coronavirus
disease
2019
(COVID-19)
pandemic,
it
has
become
obvious
that
adult
survivors
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
infection
are
susceptible
to
numerous
complications
in
various
organ
systems.
SARS-CoV-2
placental
is
an
unanticipated
complication
COVID-19
during
pregnancy.
We
hypothesize
fetal
placentitis
long-term
cardiovascular
complications.
Biodemography and Social Biology,
Journal Year:
2023,
Volume and Issue:
68(2-3), P. 87 - 100
Published: June 12, 2023
The
COVID-19
pandemic
and
its
social,
economic,
health
implications
have
generally
reduced
women's
fertility
intentions
in
different
countries.
In
this
article,
we
aimed
to
review
studies
of
the
impact
infection
on
interventions
provide
a
theoretical
basis
practical
benchmark
for
development
effective
intervention
strategies
China,
which
lifted
zero
COVID
system
early
December
2022.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Aug. 1, 2023
SARS-CoV-2
patients
have
been
reported
to
high
rates
of
secondary
Klebsiella
pneumoniae
infections.
is
a
commensal
that
typically
found
in
the
respiratory
and
gastrointestinal
tracts.
However,
it
can
cause
severe
disease
when
person's
immune
system
compromised.
Despite
number
K.
cases
patients,
co-infection
animal
model
evaluating
pathogenesis
not
available.
We
describe
mouse
study
co-infection.
BALB/cJ
mice
were
inoculated
with
mouse-adapted
followed
by
challenge
.
Mice
monitored
for
body
weight
change,
clinical
signs,
survival
during
infection.
The
bacterial
load,
viral
titers,
cell
accumulation
phenotype,
histopathology
evaluated
lungs.
co-infected
showed
higher
mortality
rate
within
48
h
had
significantly
elevated
load
lungs,
however,
loads
similar
between
single-infected
mice.
Histopathology
bronchointerstitial
pneumonia
copious
intralesional
bacteria.
Flow
cytometry
analysis
numbers
neutrophils
macrophages
Collectively,
our
results
demonstrated
causes
increased
